Aliases for SLC35A2 Gene
External Ids for SLC35A2 Gene
Previous Symbols for SLC35A2 Gene
This gene encodes a member of the nucleotide-sugar transporter family. The encoded protein is a multi-pass membrane protein. It transports UDP-galactose from the cytosol into Golgi vesicles, where it serves as a glycosyl donor for the generation of glycans. Mutations in this gene cause congenital disorder of glycosylation type IIm (CDG2M). Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
GeneCards Summary for SLC35A2 Gene
SLC35A2 (Solute Carrier Family 35 (UDP-Galactose Transporter), Member A2) is a Protein Coding gene. Diseases associated with SLC35A2 include congenital disorder of glycosylation, type iim and slc35a2-cdg. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include sugar:proton symporter activity and UDP-galactose transmembrane transporter activity. An important paralog of this gene is SLC35A5.
UniProtKB/Swiss-Prot for SLC35A2 Gene
Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function