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SLC31A2 Gene

protein-coding   GIFtS: 55
GCID: GC09P115913

Solute Carrier Family 31 (Copper Transporter), Member 2


(Previous symbol: COPT2)
  Search for SLC31A2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 31 (Copper Transporter), Member 21 2     hCTR22 3
COPT21 2 3 5     Probable Low Affinity Copper Uptake Protein 22
Copper Transporter 21 2 3     Solute Carrier Family 31 (Copper Transporters), Member 22
CTR22 3 5     SLC13A25
Solute Carrier Family 31 Member 22 3     

External Ids:    HGNC: 110171   Entrez Gene: 13182   Ensembl: ENSG000001368677   OMIM: 6030885   UniProtKB: O154323   

Export aliases for SLC31A2 gene to outside databases

Previous GC identifers: GC09P106711 GC09P107645 GC09P109366 GC09P111289 GC09P112992 GC09P114953 GC09P085521


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SLC31A2 Gene:
SLC31A2 (solute carrier family 31 (copper transporter), member 2) is a protein-coding gene. GO annotations related to this gene include copper ion transmembrane transporter activity. An important paralog of this gene is SLC31A1.

UniProtKB/Swiss-Prot: COPT2_HUMAN, O15432
Function: Involved in low-affinity copper uptake (Potential)

Gene Wiki entry for SLC31A2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NT_008470.20  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC31A2 gene promoter:
         RP58   AML1a   Olf-1   NF-kappaB   CREB   PPAR-gamma1   deltaCREB   MRF-2   NF-kappaB1   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC31A2 promoter sequence
   Search Chromatin IP Primers for SLC31A2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC31A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q32   Ensembl cytogenetic band:  9q32   HGNC cytogenetic band: 9q32

SLC31A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC31A2 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P115913:  view genomic region     (about GC identifiers)

Start:
115,913,222 bp from pter      End:
115,926,422 bp from pter
Size:
13,201 bases      Orientation:
plus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for SLC31A2

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: COPT2_HUMAN, O15432 (See protein sequence)
Recommended Name: Probable low affinity copper uptake protein 2  
Size: 143 amino acids; 15681 Da

Explore the universe of human proteins at neXtProt for SLC31A2: NX_O15432

Explore proteomics data for SLC31A2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SLC31A2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001851.1  
    ENSEMBL proteins: 
     ENSP00000259392   ENSP00000363337  

    SLC31A2 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Copper transporter 2
    SLC31 family of copper transporters

    1 InterPro protein domain:
     IPR007274 Cop_transporter

    Graphical View of Domain Structure for InterPro Entry O15432

    ProtoNet protein and cluster: O15432

    1 Blocks protein domain: IPB007274 Ctr copper transporter

    UniProtKB/Swiss-Prot: COPT2_HUMAN, O15432
    Similarity: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily


    Find genes that share domains with SLC31A2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COPT2_HUMAN, O15432
    Function: Involved in low-affinity copper uptake (Potential)

         Genatlas biochemistry entry for SLC31A2:
    solute carrier family 31,copper uptake transport,low affinity,homolog to yeast ctr2,with an alternatively spliced
    form CTR2X,ubiquitously expressed

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005375copper ion transmembrane transporter activity IEA--
         
    Find genes that share ontologies with SLC31A2           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for SLC31A2:
     Increased cilium length after   Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC31A2
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    miRNA
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    miRTarBase miRNAs that target SLC31A2:
    hsa-mir-124-3p (MIRT022361)

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    Selected qRT-PCR Assays for microRNAs that regulate SLC31A2 (see all 22):
    hsa-miR-3910 hsa-let-7d hsa-let-7c hsa-miR-449a hsa-let-7g hsa-miR-9 hsa-miR-124 hsa-let-7a
    SwitchGear 3'UTR luciferase reporter plasmidSLC31A2 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC31A2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    COPT2_HUMAN, O15432: Membrane; Multi-pass membrane protein (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane4
    cytoskeleton1
    cytosol1
    endosome1
    extracellular1
    lysosome1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral component of plasma membrane TAS9207117
    GO:0016021integral component of membrane ----

    Find genes that share ontologies with SLC31A2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC31A2
    Interactions:

        GeneGlobe Interaction Network for SLC31A2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for SLC31A2 (O154322, 3 ENSP000002593924) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAMP2O608953, ENSP000002537964I2D: score=1 STRING: ENSP00000253796
    RAMP1O608943, ENSP000002546614I2D: score=1 STRING: ENSP00000254661
    RAMP3O608963, ENSP000002422494I2D: score=1 STRING: ENSP00000242249
    --Q9WMX22MINT-7047095
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006825copper ion transport TAS9207117
    GO:0035434copper ion transmembrane transport ----

    Find genes that share ontologies with SLC31A2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC31A2 (COPT2)

    1 HMDB Compound for SLC31A2    About this table
    CompoundSynonyms CAS #PubMed Ids
    CopperCu (see all 2)7440-50-8--

    2 DrugBank Compounds for SLC31A2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    CarboplatinCBDCA (see all 2)41575-94-4transportersubstrate19509135
    CisplatinCDDP (see all 7)15663-27-1transportersubstrate19509135

    1 Novoseek inferred chemical compound relationship for SLC31A2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    copper 63.3 24 17617060 (5), 19509135 (2), 20194531 (1), 11054564 (1) (see all 7)



    Find genes that share compounds with SLC31A2           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SLC31A2 gene: 
    NM_001860.2  

    Unigene Cluster for SLC31A2:

    Solute carrier family 31 (copper transporters), member 2
    Hs.24030  [show with all ESTs]
    Unigene Representative Sequence: AK131071
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000259392(uc011lxb.2 uc004bgq.3) ENST00000490809 ENST00000374220

    miRNA
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    Block miRNA regulation of human, mouse, rat SLC31A2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLC31A2 (see all 22):
    hsa-miR-3910 hsa-let-7d hsa-let-7c hsa-miR-449a hsa-let-7g hsa-miR-9 hsa-miR-124 hsa-let-7a
    SwitchGear 3'UTR luciferase reporter plasmidSLC31A2 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat SLC31A2
      QuantiFast Probe-based Assays in human, mouse, rat SLC31A2

    Additional mRNA sequence: 

    AK057903.1 AK131071.1 AK295544.1 BC026252.1 CR407615.1 U83461.1 

    11 DOTS entries:

    DT.415604  DT.100830727  DT.100718199  DT.91732872  DT.95119320  DT.100789283  DT.121207562  DT.121207565 
    DT.91755272  DT.95192679  DT.409020 

    Selected AceView cDNA sequences (see all 202):

    CR600675 AW572808 BQ694914 AW029537 CR613559 CK430917 CR626490 BQ922540 
    CR623857 BI771145 CR593518 CR597706 CK429346 CR622921 BP355947 CR597160 
    CR609858 BM920294 BI764916 CR592959 AI460229 CD358158 CD723093 BM919547 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SLC31A2 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b
    SP1:                          -     -                 -                 -                                 
    SP2:                          -     -                 -     -           -                                 
    SP3:                          -     -           -     -     -           -                                 
    SP4:                          -     -           -     -     -           -     -     -     -               
    SP5:                                            -     -     -           -                                 


    ECgene alternative splicing isoforms for SLC31A2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC31A2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCAGGTACTG
    SLC31A2 Expression
    About this image


    SLC31A2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Neurons
             Mature Rod Cells Outer Nuclear Layer
     
     Kidney (Urinary System)
             Metanephros
     
     Blood (Hematopoietic System)
             Monocytes Peripheral Blood
     
     Eye (Sensory Organs)
             Mature Rod Cells Outer Nuclear Layer
    SLC31A2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC31A2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.24030

    UniProtKB/Swiss-Prot: COPT2_HUMAN, O15432
    Tissue specificity: Ubiquitous

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC31A2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SLC31A2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc31a21 , 5 solute carrier family 31, member 21, 5 81.32(n)1
    78.01(a)1
      4 (33.07 cM)5
    205301  NM_025286.21  NP_079562.11 
     622625625 
    chicken
    (Gallus gallus)
    Aves SLC31A21 solute carrier family 31 (copper transporters), member more 64.34(n)
    60.84(a)
      425778  NM_001277685.1  NP_001264614.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia slc31a21 solute carrier family 31 (copper transporter), member more 57.21(n)
    51.06(a)
      733902  XM_002937224.2  XP_002937270.1 
    zebrafish
    (Danio rerio)
    Actinopterygii slc31a21 solute carrier family 31 (copper transporters), member more 57.11(n)
    50.74(a)
      563012  NM_001198749.1  NP_001185678.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Ctr1B6
    Ctr1C6
    (see all 3)
    Copper transporter 1C
    (see all 3)
    20(a)
    17(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    3R(4143337-4144927)
    3R(26789011-26790042)


    ENSEMBL Gene Tree for SLC31A2 (if available)
    TreeFam Gene Tree for SLC31A2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC31A2 gene
    SLC31A12  

    Find genes that share paralogs with SLC31A2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC31A2 (see all 313)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs39236021,2
    C,F,A,H--115911257(-) GTCATT/CTCTCC 1 -- us2k1 trp322Minor allele frequency- C:0.11NS EA NA CSA WA 2480
    rs39236011,2
    C,F,A,H--115911276(-) TAGAGC/TGGAAA 1 -- us2k123Minor allele frequency- T:0.09NS EA NA WA 2768
    rs1501943821,2
    --115911540(+) TGCAAC/TAAGCT 1 -- us2k10--------
    rs1134665781,2
    C,F--115911685(+) AGCCAG/ACAAAA 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1123218211,2
    C,F--115911736(+) CAGGTG/TGGGGG 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs1493816541,2
    --115911737(+) AGGTGC/GGGGGA 1 -- us2k10--------
    rs1916174351,2
    --115911738(+) GGTGGC/GGGGAG 1 -- us2k10--------
    rs1124427501,2
    F--115911745(+) GGAGTG/AGGGTG 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs108174461,2
    C,F,A,H--115911904(+) TCCCCA/CTGGCC 1 -- us2k117Minor allele frequency- C:0.08NS EA NA WA 2340
    rs1831298271,2
    --115912045(+) TGGCTC/TACGTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SLC31A2 (115913222 - 115926422 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for SLC31A2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv466507CNV Loss19166990
    nsv831691CNV Loss17160897
    dgv8274n71CNV Gain21882294
    nsv8563CNV Gain18304495
    nsv483127CNV Complex15286789
    dgv2416e1CNV Complex17122850
    dgv2412e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603088    OMIM disorders: --


    Find genes that share disorders with SLC31A2           About GenesLikeMe

    Genetic Association Database (GAD): SLC31A2

    Export disorders for SLC31A2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC31A2 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with SLC31A2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. hCTR1: a human gene for copper uptake identified by complementation in yeast. (PubMed id 9207117)1, 2, 3, 9 Zhou B. and Gitschier J. (Proc. Natl. Acad. Sci. U.S.A. 1997)
    2. Copper transporter 2 regulates the cellular accumulation and cytotoxicity of Cisplatin and Carboplatin. (PubMed id 19509135)1, 7, 9 Blair B.G....Howell S.B. (Clin. Cancer Res. 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake. (PubMed id 17617060)1, 9 van den Berghe P.V....Klomp L.W. (Biochem. J. 2007)
    5. Ctr2 is partially localized to the plasma membrane and stimulates copper uptake in COS-7 cells. (PubMed id 17944601)1, 9 Bertinato J....L'abbAc M.R. (Biochem. J. 2008)
    6. Association of copper transporter expression with platinum resistance in epithelial ovarian cancer. (PubMed id 23564780)1 Yoshida H....Ishiko O. (Anticancer Res. 2013)
    7. The identification of novel proteins that interact with the GLP-1 receptor and restrain its activity. (PubMed id 23864651)1 Huang X....Wheeler M.B. (Mol. Endocrinol. 2013)
    8. Brain transcriptome-wide screen for HIV-1 Nef protein interaction partners reveals various membrane-associated proteins. (PubMed id 23284715)1 Kammula E.C....Willbold D. (PLoS ONE 2012)
    9. Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation. (PubMed id 21103663)1 Schaafhausen A....MA1ller C.R. (Thromb. Haemost. 2011)
    10. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)4 Vasan R.S....Benjamin E.J. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
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    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1318 HGNC: 11017 AceView: SLC31A2 Ensembl:ENSG00000136867 euGenes: HUgn1318
    ECgene: SLC31A2 H-InvDB: SLC31A2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC31A2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC31A2 gene:
    Search GeneIP for patents involving SLC31A2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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