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SLC30A7 Gene

protein-coding   GIFtS: 52
GCID: GC01P101361

Solute Carrier Family 30 (Zinc Transporter), Member 7

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 30 (Zinc Transporter), Member 71 2     ZnTL22
ZNT72 3 5     Zinc Transporter 72
Solute Carrier Family 30 Member 72 3     Zinc Transporter Like 22
Znt-Like Transporter 22 3     Zinc Transporter ZnT-72
ZnT-72 3     ZNTL23

External Ids:    HGNC: 193061   Entrez Gene: 1488672   Ensembl: ENSG000001626957   OMIM: 6111495   UniProtKB: Q8NEW03   

Export aliases for SLC30A7 gene to outside databases

Previous GC identifers: GC01P100542 GC01P100652 GC01P100824 GC01P101073 GC01P101134 GC01P099486


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC30A7 Gene:
Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and
intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion
facilitator family, such as SLC30A7, permit cellular efflux of zinc (Seve et al., 2004 (PubMed
15154973)).(supplied by OMIM, Mar 2008)

GeneCards Summary for SLC30A7 Gene:
SLC30A7 (solute carrier family 30 (zinc transporter), member 7) is a protein-coding gene. Diseases associated with SLC30A7 include acrodermatitis, and enteropathica. GO annotations related to this gene include cation transmembrane transporter activity. An important paralog of this gene is SLC30A5.

UniProtKB/Swiss-Prot: ZNT7_HUMAN, Q8NEW0
Function: Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates
cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases
(ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate,
thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity)

Gene Wiki entry for SLC30A7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC30A7 gene promoter:
         RFX1   FOXJ2 (long isoform)   FOXJ2   STAT5A   c-Ets-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC30A7 promoter sequence
   Search Chromatin IP Primers for SLC30A7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC30A7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p21.2   Ensembl cytogenetic band:  1p21.2   HGNC cytogenetic band: 1p21.1

SLC30A7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC30A7 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P101361:  view genomic region     (about GC identifiers)

Start:
101,361,632 bp from pter      End:
101,447,311 bp from pter
Size:
85,680 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZNT7_HUMAN, Q8NEW0 (See protein sequence)
Recommended Name: Zinc transporter 7  
Size: 376 amino acids; 41626 Da
Subunit: Homooligomer
Secondary accessions: B2R949 D3DT61 Q8TCH2

Explore the universe of human proteins at neXtProt for SLC30A7: NX_Q8NEW0

Explore proteomics data for SLC30A7 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys15
  • Modification sites at PhosphoSitePlus

  • See SLC30A7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001138356.1  NP_598003.2  

    ENSEMBL proteins: 
     ENSP00000359130   ENSP00000350278   ENSP00000359129  
    Reactome Protein details: Q8NEW0

    SLC30A7 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Zinc transporter 7
    SLC30 zinc transporter family

    2 InterPro protein domains:
     IPR027469 Cation_efflux_TMD
     IPR002524 Cation_efflux

    Graphical View of Domain Structure for InterPro Entry Q8NEW0

    ProtoNet protein and cluster: Q8NEW0

    1 Blocks protein domain: IPB002524 Cation efflux protein

    UniProtKB/Swiss-Prot: ZNT7_HUMAN, Q8NEW0
    Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily


    SLC30A7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZNT7_HUMAN, Q8NEW0
    Function: Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates
    cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases
    (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate,
    thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity)
    Induction: Increased intracellular zinc level, resulting from extracellular zinc supplementation, do not induce
    any up- or down-regulation of gene expression. Up-regulated by zinc depletion

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008324cation transmembrane transporter activity IEA--
         
    SLC30A7 for ontologies           About GeneDecksing


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Slc30a7):
     adipose tissue  behavior/neurological  digestive/alimentary  growth/size/body  homeostasis/metabolism 

    SLC30A7 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC30A7
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    miRNA
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    miRTarBase miRNAs that target SLC30A7:
    hsa-mir-124-3p (MIRT002641), hsa-mir-221-3p (MIRT046965), hsa-mir-155-5p (MIRT020907), hsa-let-7b-5p (MIRT032430), hsa-mir-193b-3p (MIRT016502)

    Block miRNA regulation of human, mouse, rat SLC30A7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLC30A7 (see all 115):
    hsa-miR-323-3p hsa-miR-1321 hsa-miR-3607-3p hsa-miR-607 hsa-miR-188-5p hsa-miR-106a hsa-miR-218-1* hsa-miR-128
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC30A7


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZNT7_HUMAN, Q8NEW0: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus4
    plasma membrane3

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0005737cytoplasm IDA17349999
    GO:0005794Golgi apparatus IDA--
    GO:0016021integral component of membrane IEA--
    GO:0016023cytoplasmic membrane-bounded vesicle IEA--

    SLC30A7 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SLC30A7 About    
    See pathways by source

    SuperPathContained pathways About
    1Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    SLC-mediated transmembrane transport0.47
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    Transmembrane transport of small molecules0.47
    2Metal ion SLC transporters
    Metal ion SLC transporters
    Zinc transporters0.00
    Zinc efflux and compartmentalization by the SLC30 family0.00
    3Peptide hormone metabolism
    Peptide hormone metabolism0.30
    Insulin Processing0.30
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 Reactome Pathways for SLC30A7
        Zinc efflux and compartmentalization by the SLC30 family
    Insulin processing



    SLC30A7 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC30A7
    Interactions:

        Search GeneGlobe Interaction Network for SLC30A7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    Selected Interacting proteins for SLC30A7 (Q8NEW03 ENSP000003502784) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CD40P259423, ENSP000003613594I2D: score=2 STRING: ENSP00000361359
    INS-IGF2ENSP000003489864STRING: ENSP00000348986
    UBCENSP000003448184STRING: ENSP00000344818
    PIGNENSP000003502634STRING: ENSP00000350263
    ARHGEF7ENSP000003648934STRING: ENSP00000364893
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006812cation transport ----
    GO:0006829zinc ion transport IEA--
    GO:0032119sequestering of zinc ion IEA--
    GO:0044267cellular protein metabolic process TAS--
    GO:0055085transmembrane transport TAS--

    SLC30A7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC30A7 (ZNT7)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SLC30A7 gene (2 alternative transcripts): 
    NM_001144884.1  NM_133496.4  

    Unigene Cluster for SLC30A7:

    Solute carrier family 30 (zinc transporter), member 7
    Hs.533903  [show with all ESTs]
    Unigene Representative Sequence: NM_133496
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370112(uc001dtn.2 uc001dto.2) ENST00000357650 ENST00000370111

    miRNA
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    Block miRNA regulation of human, mouse, rat SLC30A7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLC30A7 (see all 115):
    hsa-miR-323-3p hsa-miR-1321 hsa-miR-3607-3p hsa-miR-607 hsa-miR-188-5p hsa-miR-106a hsa-miR-218-1* hsa-miR-128
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      QuantiTect SYBR Green Assays in human, mouse, rat SLC30A7
      QuantiFast Probe-based Assays in human, mouse, rat SLC30A7

    Additional mRNA sequence: 

    AF233345.1 AF529197.1 AK023089.1 AK313638.1 AY094606.1 BC064692.1 BX537375.1 BX640630.1 
    BX648884.1 CR936806.1 

    9 DOTS entries:

    DT.97836395  DT.101982541  DT.121442662  DT.95361141  DT.121442667  DT.121442793  DT.75125997  DT.91803880 
    DT.101959703 

    Selected AceView cDNA sequences (see all 156):

    AI241033 AI245002 AU130540 AI088029 BX648884 AL700318 AI189239 BM717753 
    AA311915 CB989038 BU682542 NM_133496 BQ953816 BM142196 AW083910 AA884217 
    AF529197 AI742593 BF434559 BG574433 CD677505 BM674946 AI913377 BC064692 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC30A7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SLC30A7 Expression
    About this image


    SLC30A7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Heart (Cardiovascular System)
             Outflow Tract
    SLC30A7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC30A7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.533903
        Custom PCR Arrays for SLC30A7
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC30A7 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc30a71 , 5 solute carrier family 30 (zinc transporter), member more1, 5 89.98(n)1
    96.28(a)1
      3 (50.16 cM)5
    665001  NM_023214.71  NP_075703.11 
     1159389735 
    chicken
    (Gallus gallus)
    Aves SLC30A71 solute carrier family 30 (zinc transporter), member more 77.84(n)
    83.24(a)
      424464  NM_001008788.1  NP_001008788.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC30A76
    solute carrier family 30 (zinc transporter), membe...
    80(a)
    1 ↔ 1
    4(87455776-87501486)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia MGC761892 hypothetical protein MGC76189 75.74(n)    BC063918.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi11a082 wufi11a08 74.16(n)   327439  BC044151.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG66721 CG6672 59.81(n)
    63.14(a)
      41342  NM_141792.3  NP_650049.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MSC26
    Member of the cation diffusion facilitator family,...
    14(a)
    1 → many
    IV(859346-861520) YDR205W


    ENSEMBL Gene Tree for SLC30A7 (if available)
    TreeFam Gene Tree for SLC30A7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC30A7 gene
    SLC30A52  SLC30A62  
    1 SIMAP similar gene for SLC30A7 using alignment to 2 protein entries:     ZNT7_HUMAN (see all proteins):
    SLC30A5

    SLC30A7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC30A7 (see all 1491)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1432475291,2
    C--101362944(+) TCTTAA/TGAAGT 2 -- int10--------
    rs1483152551,2
    --101363028(+) CTGATA/GAAAGC 2 -- int10--------
    rs1917784811,2
    --101363081(+) TTCCCC/TGTACT 2 -- int10--------
    rs1162830421,2
    C,F--101363278(+) TCAACC/TGTCAA 2 -- int11Minor allele frequency- T:0.06WA 118
    rs1824145101,2
    --101363626(+) TATCAA/GGAGTG 2 -- int10--------
    rs1486131291,2
    C--101363667(+) CAAGA-/GTGTATC 2 -- int10--------
    rs1406133851,2
    --101363681(+) AGCTTA/GTATAT 2 -- int10--------
    rs1874120391,2
    --101363716(+) CATAGA/CTTATA 2 -- int10--------
    rs1930225441,2
    --101363719(+) AGCTTA/GTATAT 2 -- int10--------
    rs746003131,2
    C,F--101363740(+) CTACAG/CATAGT 2 -- int11Minor allele frequency- C:0.05WA 118

    HapMap Linkage Disequilibrium report for SLC30A7 (101361632 - 101447311 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for SLC30A7:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2666592CNV Deletion23128226
    esv5152CNV Deletion18987735
    esv2715407CNV Deletion23290073
    esv1088978CNV Insertion17803354
    nsv522064CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611149    OMIM disorders: --

    9 diseases for SLC30A7:    
    About MalaCards
    acrodermatitis    enteropathica    acrodermatitis enteropathica    peritonitis
    multiple sclerosis    alzheimer's disease    prostate cancer    prostatitis
    malaria


    SLC30A7 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC30A7
    Human Genome Epidemiology (HuGE) Navigator: SLC30A7 (1 document)

    Export disorders for SLC30A7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC30A7 gene, integrated from 10 sources (see all 29):
    (articles sorted by number of sources associating them with SLC30A7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ZnT7, a novel mammalian zinc transporter, accumulates zinc in the Golgi apparatus. (PubMed id 12446736)1, 2, 3 Kirschke C.P. and Huang L. (J. Biol. Chem. 2003)
    2. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. (PubMed id 21833088)1, 4  ....Compston A. (Nature 2011)
    3. Polymorphisms in mitochondrial genes and prostate cancer risk. (PubMed id 19064571)1, 4 Wang L....Thibodeau S.N. (amp 2008)
    4. Differential regulation of zinc efflux transporters ZnT-1, ZnT-5 and ZnT-7 gene expression by zinc levels: a real-time RT-PCR study. (PubMed id 15276077)1, 2 Devergnas S.... Seve M. (Biochem. Pharmacol. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Zinc transporter 5 and zinc transporter 7 induced by high glucose protects peritoneal mesothelial cells from undergoing apoptosis. (PubMed id 23275032)1 Zhang X....Ma J. (Cell. Signal. 2013)
    7. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 JAoger S....Krogan N.J. (Nature 2012)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (J. Biol. Chem. 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 148867 HGNC: 19306 AceView: SLC30A7 Ensembl:ENSG00000162695 euGenes: HUgn148867
    ECgene: SLC30A7 H-InvDB: SLC30A7

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC30A7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC30A7 gene:
    Search GeneIP for patents involving SLC30A7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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