SLC30A5 Gene
protein-coding GIFtS: 53
GCID: GC05P068389
|
|
solute carrier family 30 (zinc transporter), member 5
| |
Aliases
for SLC30A5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Solute Carrier Family 30 (Zinc Transporter), Member 51 2 | | FLJ127561 | | ZNT51 2 3 5 | | MGC54991 | | ZTL11 2 3 5 | | Zinc Transporter 52 | | ZNTL11 2 3 | | Zinc Transporter ZTL12 | | ZnT-51 2 3 | | HZTL11 | | ZnT-Like Transporter 12 3 | | Solute Carrier Family 30 Member 53 | | FLJ124961 | | |
Export aliases for SLC30A5 gene to outside databasesPrevious GC identifers: GC05P068541 GC05P069955 GC05P068360 GC05P068405 GC05P068369 GC05P068425 GC05P065345 |
Summaries
for SLC30A5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SLC30A5:
This gene encodes a member of the SLC30A/ZnT family of zinc transporter proteins. ZnT proteins mediate both cellularzinc efflux and zinc sequestration into membrane-bound organelles. The encoded protein plays a role in the earlysecretory pathway as a heterodimer with zinc transporter 6, and may also regulate zinc sequestration into secretorygranules of pancreatic beta cells. Alternatively spliced transcript variants encoding multiple isoforms have beenobserved for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. (provided byRefSeq, Oct 2011)
UniProtKB/Swiss-Prot: ZNT5_HUMAN, Q8TAD4Function: Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulincrystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes,alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments whereALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP
|
Genomic Views
for SLC30A5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006713.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SLC30A5 gene promoter:
HTF FOXJ2 (long isoform) FOXJ2 Tal-1beta ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for SLC30A5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC30A5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q12.1 Ensembl cytogenetic band: 5q13.1 HGNC cytogenetic band: 5q13.1SLC30A5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P068389: view genomic region
(about GC identifiers)
Start:
|
68,389,473 bp from pter |
End:
|
68,426,896 bp from pter |
Size:
|
37,424 bases |
Orientation:
|
plus strand |
|
Proteins
for SLC30A5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZNT5_HUMAN, Q8TAD4 (See
protein sequence)Recommended Name: Zinc transporter 5 Size: 765 amino acids; 84047 Da
Subunit: Heterooligomer. Interacts with ZNT6
Subcellular location: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Perimeter ofgranules, localizes to the brush border membrane of the enterocyte. Concentrated in early compartments of thesecretory pathway such as COPII-coated vesicles
Miscellaneous: The histidine-rich loop is essential for ZNT5 and ZNT6 heterooligomeric complexes to activate TNAP
Sequence caution: Sequence=BAB14258.1; Type=Erroneous initiation;
Secondary accessions: B7ZM89 Q6UX54 Q7L4M4 Q8TDG3 Q9BVY8 Q9H9H1Alternative splicing: 4 isoforms: Q8TAD4-1 Q8TAD4-2 Q8TAD4-3 Q8TAD4-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SLC30A5: NX_Q8TAD4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TAD4
SLC30A5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001238898.1 NP_075053.2 NP_076960.1
ENSEMBL proteins: ENSP00000379836 ENSP00000370241 ENSP00000426751 ENSP00000421251 ENSP00000427111 ENSP00000423078 Reactome Protein details: Q8TAD4
Human Recombinant Protein Products for SLC30A5:
Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10): About this table
SLC30A5 for ontologies About GeneDecksing
SLC30A5 Antibody Products:
Assay Products for SLC30A5: |
Protein
Domains /
Families
for SLC30A5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SLC30A5 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8TAD4ProtoNet protein and cluster: Q8TAD4 1 Blocks protein family: IPB002524 Cation efflux protein
UniProtKB/Swiss-Prot: ZNT5_HUMAN, Q8TAD4Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily |
Function
for SLC30A5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZNT5_HUMAN, Q8TAD4Function: Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulincrystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes,alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments whereALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAPInduction: Increased intracellular zinc level, resulting from extracellular zinc supplementation, do not induce any up-or down-regulation of gene expression. Up-regulated by zinc depletion Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
SLC30A5 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for SLC30A5:
7 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Slc30a5):
SLC30A5 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Slc30a5tm1Ynak for SLC30A5
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC30A5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC30A5 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SLC30A5 (NM_022902) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC30A5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC30A5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC30A5 |
|
Pathways & Interactions
for SLC30A5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Zinc transporters | | | 2 | SLC-mediated transmembrane transport | | | 3 | Insulin Processing | | | 4 | Asparagine N-linked glycosylation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/10 
Reactome Pathways for SLC30A5 (see all 10)
SLC30A5 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC30A5
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
3 Interacting proteins for SLC30A5 (ENSP000003798364) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
SLC30A5 for ontologies About GeneDecksing
|
Drugs & Compounds
for SLC30A5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SLC30A5 for compounds About GeneDecksing
 Browse Tocris compounds for SLC30A5
1 HMDB Compound for SLC30A5 About this table
1 Novoseek chemical compound relationship for SLC30A5 gene About this table
Search CenterWatch for drugs/clinical trials and news about SLC30A5 / ZNT5
|
Transcripts
for SLC30A5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SLC30A5 gene (3 alternative transcripts): NM_001251969.1 NM_022902.4 NM_024055.4 Unigene Cluster for SLC30A5: Solute carrier family 30 (zinc transporter), member 5 Hs.631975 [show with all ESTs]Unigene Representative Sequence: NM_0229028 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000396591(uc003jvh.3 uc003jvj.3 uc003jvk.3) ENST00000380860(uc003jvg.3 uc011crc.2)
ENST00000504103 ENST00000502979 ENST00000507354(uc003jvi.3) ENST00000513937
ENST00000512367 ENST00000511158
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC30A5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC30A5 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): SLC30A5 (NM_022902) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC30A5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC30A5 |
Additional cDNA sequence: AF212235.1 AF461760.1 AK022558.1 AK022818.1 AK292925.1 AL833716.1 AY089991.1 AY358505.1 BC000808.1 BC003411.1 BC008198.1 BC017441.1 BC130452.1 BC130454.1 BC144349.1 BX537394.1 JF802034.1 8 DOTS entries: DT.441572 DT.100789490 DT.100789482 DT.100789487 DT.100789486 DT.91760957 DT.91999517 DT.95229902 24/172 AceView cDNA sequences (see all 172): N68128 AI758705 AF461760 AI762854 CA422485 BM564843 NM_024055 BC017441 AI800271 BX956264 BQ438983 AW613130 AA598723 BE883319 BX537394 BP352932 AI804954 AL833716 AA761684 BQ440211 AI913535 CD244170 NM_022902 AA491093
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for SLC30A5 (see all 12) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15a | · |
|---|
|
| SP1: | | | | | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | - | | |
| SP4: | | | | | | | | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | |
| ExUns: | 15b | · | 15c | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | · | 18c | · | 18d |
|---|
|
| SP1: | | | - | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | |
| SP3: | | | - | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | |
| SP5: | | | - | | - | | - | | | | | | | | | |
ECgene alternative splicing isoforms for SLC30A5
|
Expression
for SLC30A5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SLC30A5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGTTGCTGG
About this image
See SLC30A5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC30A5
SOURCE GeneReport for Unigene cluster: Hs.631975
UniProtKB/Swiss-Prot: ZNT5_HUMAN, Q8TAD4Tissue specificity: Ubiquitously expressed. Highly expressed in pancreas, liver and kidney. Expressed abundantly ininsulin-containing beta cells, undetectable in other endocrine cell types including glucagon-secreting alpha cells andmost acinar cells
SABiosciences Custom PCR Arrays for SLC30A5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC30A5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC30A5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC30A5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC30A5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC30A5 |
Orthologs
for SLC30A5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SLC30A5 gene from 8/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Slc30a51 , 5 |
solute carrier family 30 (zinc transporter), member more1, 5 |
89.44(n)1
95.4(a)1 |
|
13 (53.23 cM)5
690481 NM_022885.21 NP_075023.21
1008026495 |
chicken
(Gallus gallus) |
Aves |
SLC30A51 |
solute carrier family 30 (zinc transporter), member more |
80.88(n)
89.34(a) |
|
427173 NM_001031419.2 NP_001026590.2 |
lizard
(Anolis carolinensis) |
Reptilia |
SLC30A56 |
-- |
85(a) |
1 ↔ 1 |
2(12334591-12362251) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.331192 |
Xenopus laevis transcribed sequence with moderate similarity more |
74.93(n) |
|
48061894 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufi03d072 |
Transcribed sequence with weak similarity to protein more |
73.94(n) |
|
57062509 |
worm
(Caenorhabditis elegans) |
Secernentea |
CELE_Y105E8A.31 |
Protein Y105E8A.3 |
51.41(n)
44.3(a) |
|
173299 NM_170935.6 NP_740931.2 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT2G046206AT3G121006 |
metal tolerance protein C2 |
24(a)22(a) |
many → 1possible ortholog |
2(1610506-1612902) 3(3854515-3857319) |
rice
(Oryza sativa) |
Liliopsida |
---- |
cation efflux family protein, putative, expressed |
23(a)21(a) |
many → 1possible ortholog |
8(20216356-20219272) 2(35801176-35806577) |
ENSEMBL Gene Tree for SLC30A5 (if available)
TreeFam Gene Tree for SLC30A5 (if available) |
Paralogs
for SLC30A5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SLC30A5 gene
- SLC30A72 SLC30A62
1 SIMAP similar gene for SLC30A5 using alignment to 4 protein entries: ZNT5_HUMAN (see all proteins):SLC30A7
SLC30A5 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for SLC30A5
PGOHUM00000234358
|
Genomic Variants
for SLC30A5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SLC30A5 (68389473 - 68426896 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SLC30A5: --
Human Gene Mutation Database (HGMD): SLC30A5
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC30A5 |
|
Disorders
/ Diseases
for SLC30A5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SLC30A5 for disorders About GeneDecksing
OMIM gene information: 607819
OMIM disorders: --
9  diseases for SLC30A5: About MalaCardsacrodermatitis enteropathica pancreatitis enteropathica nonsyndromic deafness
acrodermatitis alzheimer's disease lung cancer pneumonia
prostatitis
1 disease from the University of Copenhagen DISEASES database for SLC30A5:Acrodermatitis enteropathica Human Genome Epidemiology (HuGE) Navigator: SLC30A5 (2 documents)
Export disorders for SLC30A5 gene to outside databases
|
Publications
for SLC30A5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SLC30A5 gene, integrated from 9 sources (see all 33):
(articles sorted by number of sources associating them with SLC30A5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells. (PubMed id 11904301)1, 2, 3, 9 Kambe T....Nagao M. (2002)
- A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane. (PubMed id 11937503)1, 2, 3 Cragg R.A.... Ford D. (2002)
- Differential regulation of zinc efflux transporters ZnT-1, ZnT-5 and ZnT-7 gene expression by zinc levels: a real-time RT-PCR study. (PubMed id 15276077)1, 2 Devergnas S.... Seve M. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Histidine pairing at the metal transport site of mamma lian ZnT transporters controls Zn2+ over Cd2+ selectivity. (PubMed id 22529353)1 Hoch E....Sekler I. (2012)
- Differential subcellular localization of the splice v ariants of the zinc transporter ZnT5 is dictated by the different C-terminal re gions. (PubMed id 21887337)1 Thornton J.K....Valentine R.A. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
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External Searches for SLC30A5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing SLC30A5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing SLC30A5 gene
(According to HUGE)
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Specialized Databases showing SLC30A5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for SLC30A5 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for SLC30A5 gene:
Search GeneIP for patents involving SLC30A5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SLC30A5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SLC30A5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC30A5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC30A5 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SLC30A5 | | OriGene 3'-UTR Clone for SLC30A5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC30A5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC30A5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC30A5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC30A5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC30A5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC30A5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC30A5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC30A5 |
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| | | | Search Tocris compounds for SLC30A5 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC30A5 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for SLC30A5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC30A5 |
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