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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC30A3 Gene

protein-coding   GIFtS: 56
GCID: GC02M027476

Solute Carrier Family 30 (Zinc Transporter), Member 3


(Previous symbol: ZNT3)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 30 (Zinc Transporter), Member 31 2     Zinc Transporter ZnT-32
ZNT31 2 3 5     znT-32
Solute Carrier Family 30 Member 32 3     ZnT-33
Zinc Transporter 32     

External Ids:    HGNC: 110141   Entrez Gene: 77812   Ensembl: ENSG000001151947   OMIM: 6028785   UniProtKB: Q997263   

Export aliases for SLC30A3 gene to outside databases

Previous GC identifers: GC02M027398 GC02M027570 GC02M027452 GC02M027454 GC02M027388 GC02M027330 GC02M027219


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SLC30A3 Gene: 
SLC30A3 (solute carrier family 30 (zinc transporter), member 3) is a protein-coding gene. Diseases associated with SLC30A3 include borna disease, and alzheimer's disease, and among its related super-pathways are Transmembrane transport of small molecules and Zinc transporters. GO annotations related to this gene include zinc transporting ATPase activity. An important paralog of this gene is SLC30A2.

UniProtKB/Swiss-Prot: ZNT3_HUMAN, Q99726
Function: Involved in accumulation of zinc in synaptic vesicles (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_022184.15  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC30A3 gene promoter:
         E2F-4   E2F-3a   E2F-5   Bach2   Nkx2-5   E2F-2   LCR-F1   Arnt   E2F   E2F-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC30A3 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC30A3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC30A3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p23.3   Ensembl cytogenetic band:  2p23.3   HGNC cytogenetic band: 2p23.3

SLC30A3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC30A3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M027476:  view genomic region     (about GC identifiers)

Start:
27,476,552 bp from pter      End:
27,498,685 bp from pter
Size:
22,134 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZNT3_HUMAN, Q99726 (See protein sequence)
Recommended Name: Zinc transporter 3  
Size: 388 amino acids; 41945 Da
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane
protein (Probable). Cell junction, synapse, synaptosome (By similarity)
Secondary accessions: Q8TC03

Explore the universe of human proteins at neXtProt for SLC30A3: NX_Q99726

Explore proteomics data for SLC30A3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q99726

  • SLC30A3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC30A3 Protein Expression
    REFSEQ proteins: NP_003450.2  
    ENSEMBL proteins: 
     ENSP00000233535   ENSP00000388219   ENSP00000414320   ENSP00000393545   ENSP00000403959  
     ENSP00000403912   ENSP00000392673   ENSP00000415226  
    Reactome Protein details: Q99726
    Human Recombinant Protein Products for SLC30A3: 
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    Novus Biologicals SLC30A3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SLC30A3 

    Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA17349999
    GO:0005768endosome TAS8962159
    GO:0005770late endosome IDA17349999
    GO:0005887integral to plasma membrane TAS8962159
    GO:0008021synaptic vesicle TAS8962159

    SLC30A3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Zinc transporter 3 
    SLC30 zinc transporter family

    2 InterPro protein domains:
     IPR027469 Cation_efflux_TMD
     IPR002524 Cation_efflux

    Graphical View of Domain Structure for InterPro Entry Q99726

    ProtoNet protein and cluster: Q99726

    1 Blocks protein domain: IPB002524 Cation efflux protein

    UniProtKB/Swiss-Prot: ZNT3_HUMAN, Q99726
    Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily


    SLC30A3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZNT3_HUMAN, Q99726
    Function: Involved in accumulation of zinc in synaptic vesicles (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008324cation transmembrane transporter activity ----
    GO:0015633zinc transporting ATPase activity TAS8962159
         
    SLC30A3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC30A3:
     Synthetic lethal with Ras 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Slc30a3):
     homeostasis/metabolism  nervous system  other 

    SLC30A3 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC30A3 
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    SwitchGear 3'UTR luciferase reporter plasmidSLC30A3 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC30A3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1SLC-mediated transmembrane transport
    SLC-mediated transmembrane transport0.50
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    Transmembrane transport of small molecules0.50
    2Zinc transporters
    Zinc transporters0.68
    Zinc efflux and compartmentalization by the SLC30 family0.41
    Metal ion SLC transporters0.68

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/6        Reactome Pathways for SLC30A3 (see all 6)
        Zinc efflux and compartmentalization by the SLC30 family
    SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Metal ion SLC transporters



    SLC30A3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC30A3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for SLC30A3 (Q997263 ENSP000002335354) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AP3B1O002033, ENSP000002551944I2D: score=3 STRING: ENSP00000255194
    AP3D1O146173, ENSP000003440554I2D: score=2 STRING: ENSP00000344055
    AP3S1Q925723, ENSP000003253694I2D: score=2 STRING: ENSP00000325369
    YWHABP319463I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport TAS8962159
    GO:0006812cation transport ----
    GO:0051050positive regulation of transport IEA--
    GO:0055085transmembrane transport TAS--
    GO:0061088regulation of sequestering of zinc ion IDA17349999

    SLC30A3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC30A3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC30A3 (ZNT3)

    1 Novoseek inferred chemical compound relationship for SLC30A3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    zinc 67.5 43 15860731 (6), 8962159 (3), 14662799 (3), 19521526 (2) (see all 12)

    Search CenterWatch for drugs/clinical trials and news about SLC30A3 / ZNT3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC30A3 gene: 
    NM_003459.4  

    Unigene Cluster for SLC30A3:

    Solute carrier family 30 (zinc transporter), member 3
    Hs.467981  [show with all ESTs]
    Unigene Representative Sequence: AK127300
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000497341(uc002rjj.3) ENST00000482990 ENST00000233535(uc002rjk.3 uc010ylh.2)
    ENST00000445870 ENST00000432351 ENST00000426924 ENST00000424577 ENST00000486309
    ENST00000450118 ENST00000426569 ENST00000447008
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/34 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC30A3 (see all 34):
    hsa-miR-642a hsa-miR-3194-5p hsa-miR-106a hsa-miR-29a hsa-miR-449a hsa-miR-9 hsa-miR-93 hsa-miR-133a
    SwitchGear 3'UTR luciferase reporter plasmidSLC30A3 3' UTR sequence
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    Additional mRNA sequence: 

    AK127096.1 AK127300.1 AK302174.1 AK313600.1 BC028358.2 U76010.1 

    7 DOTS entries:

    DT.455877  DT.100648846  DT.101975540  DT.75189631  DT.97762692  DT.97803202  DT.91740278 

    24/33 AceView cDNA sequences (see all 33):

    BI754180 AK127096 BP369010 BC028358 BU633568 NM_003459 BM554028 CR605101 
    AK127300 BM552602 U76010 BX349088 BM560506 BM925306 CA423384 BI520363 
    BX283698 BG772695 AL580043 AL046404 BM551613 BM909692 AL558140 AA629061 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SLC30A3 (see all 7)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10
    SP1:                    -     -                 -                             -                       -         
    SP2:        -     -     -     -                 -                                                               
    SP3:                    -     -                 -           -     -     -     -                                 
    SP4:                          -     -           -                                                               
    SP5:                                                                                                  -         


    ECgene alternative splicing isoforms for SLC30A3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC30A3 expression in normal human tissues (normalized intensities)      SLC30A3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SLC30A3 Expression
    About this image


    SLC30A3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 6 entries
             Metencephalon
             brain/midbrain/lateral wall   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Medulla Oblongata
             brain/midbrain/lateral wall   
     
     Endothelium (Gastrointestinal Tract)    fully expand to see all 4 entries
             Human Renal Glomerular Endothelial Cells (HRGEC)   
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             Juxtaglomerular Cells Afferent Arteriole
             Human Renal Glomerular Endothelial Cells (HRGEC)   
     
     Smooth Muscle (Muscoskeletal System)
             Juxtaglomerular Cells Afferent Arteriole

    See SLC30A3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC30A3

    SOURCE GeneReport for Unigene cluster: Hs.467981
        SABiosciences Custom PCR Arrays for SLC30A3
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC30A3 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc30a31 , 5 solute carrier family 30 (zinc transporter), member more1, 5 86.43(n)1
    89.18(a)1
      5 (16.97 cM)5
    227841  NM_011773.31  NP_035903.21 
     310861065 
    lizard
    (Anolis carolinensis)
    Reptilia SLC30A36
    Uncharacterized protein
    58(a)
    1 ↔ 1
    AAWZ02035537(30352-43397)
    zebrafish
    (Danio rerio)
    Actinopterygii slc30a26
    solute carrier family 30 (zinc transporter), membe...
    47(a)
    1 ↔ 1
    20(38620726-38642219)
    fruit fly
    (Drosophila melanogaster)
    Insecta BG:DS07295.13 heavy metal ion porter 33(a)     --
    worm
    (Caenorhabditis elegans)
    Secernentea T18D3.33 cobalt uptake like protein 41(a)
    (best of 3)
      X(12499995-12502401)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ZRC16
    COT16
    Vacuolar membrane zinc transporter, transports zin...
    Vacuolar transporter that mediates zinc transport ...
    20(a)
    19(a)
    many ↔ many
    many ↔ many
    XIII(754838-756166)
    XV(906236-907555)


    ENSEMBL Gene Tree for SLC30A3 (if available)
    TreeFam Gene Tree for SLC30A3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC30A3 gene
    SLC30A22  SLC30A82  SLC30A102  SLC30A42  SLC30A12  
    4 SIMAP similar genes for SLC30A3 using alignment to 8 protein entries:     ZNT3_HUMAN (see all proteins):
    SLC30A8    SLC30A4    ZNT4    SLC30A2

    SLC30A3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/239 SNPs in SLC30A3 are shown (see all 239)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs19753831,2
    C--27476992(+) GGCTGC/GTATCA 1 -- ds50014Minor allele frequency- G:0.07MN NA WA 306
    rs1886601721,2
    --27477238(+) AGGACC/GCAGGC 1 -- ds50010--------
    rs1510870251,2
    --27477302(+) TCTGAA/GGGTGG 1 -- ds50010--------
    rs2003650371,2
    C--27477425(+) CAGCA-/CCACAG 1 -- ds50010--------
    rs1410147031,2
    --27477428(+) GCACAC/TAGGCT 1 -- ds50010--------
    rs38208301,2
    C,F,H--27477476(+) GCAGCG/AGAGTC 1 -- ut31 ese39Minor allele frequency- A:0.05NS EA 1230
    rs1465044301,2
    --27477539(+) ATAGAA/CCCCCA 1 -- ut310--------
    rs1145673111,2
    C,F--27477547(+) CCAAAC/TAGACA 1 -- ut311Minor allele frequency- T:0.03WA 118
    rs1390700201,2
    C--27477605(+) CAGAGA/GCACAC 1 -- ut310--------
    rs1929638021,2
    --27477655(+) ACACAA/CACACA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SLC30A3 (27476552 - 27498685 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SLC30A3:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv873754CNV Loss21882294
    nsv833603CNV Loss17160897


    Human Gene Mutation Database (HGMD): SLC30A3
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC30A3
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC30A3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602878    OMIM disorders: --

    4 diseases for SLC30A3:    About MalaCards
    borna disease    alzheimer's disease    pneumonia    neuronitis


    SLC30A3 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for SLC30A3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC30A3 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with SLC30A3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ZnT-3, a putative transporter of zinc into synaptic vesicles. (PubMed id 8962159)1, 2, 3, 9 Palmiter R.D.... Findley S.D. (1996)
    2. SLC30A3 (ZnT3) oligomerization by dityrosine bonds re gulates its subcellular localization and metal transport capacity. (PubMed id 19521526)1, 9 Salazar G....Faundez V. (2009)
    3. The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation. (PubMed id 14657250)1, 9 Salazar G....Faundez V. (2004)
    4. Zinc and metallothionein levels and expression of zinc transporters in androgen-independent subline of LNCaP cells. (PubMed id 14662799)1, 9 Iguchi K....Hirano K. (2004)
    5. Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomes. (PubMed id 17349999)1, 9 Falcon-Perez J.M. and Dell'Angelica E.C. (2007)
    6. Abundant expression of zinc transporters in the amyloid plaques of Alzheimer's disease brain. (PubMed id 18639746)1 Zhang L.H....Wang Z.Y. (2008)
    7. Intracellular zinc homeostasis in leukocyte subsets is regulated by different expression of zinc exporters ZnT-1 to ZnT-9. (PubMed id 17971500)1 Overbeck S.... Rink L. (2008)
    8. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
    9. In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression. (PubMed id 15154973)1 Seve M.... Favier A. (2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7781 HGNC: 11014 AceView: SLC30A3 Ensembl:ENSG00000115194 euGenes: HUgn7781
    ECgene: SLC30A3 H-InvDB: SLC30A3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC30A3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC30A3 gene:
    Search GeneIP for patents involving SLC30A3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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