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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC30A1 Gene

protein-coding   GIFtS: 59
GCID: GC01M211744

Solute Carrier Family 30 (Zinc Transporter), Member 1


(Previous symbol: ZNT1)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 30 (Zinc Transporter), Member 11 2     Zinc Transporter 12
ZNT11 2 3 5     znT-12
Solute Carrier Family 30 Member 12 3     ZnT-13
ZRC12     

External Ids:    HGNC: 110121   Entrez Gene: 77792   Ensembl: ENSG000001703857   OMIM: 6095215   UniProtKB: Q9Y6M53   

Export aliases for SLC30A1 gene to outside databases

Previous GC identifers: GC01M210481 GC01M207611 GC01M208387 GC01M208828 GC01M208137 GC01M209811 GC01M182425


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SLC30A1 Gene: 
SLC30A1 (solute carrier family 30 (zinc transporter), member 1) is a protein-coding gene. Diseases associated with SLC30A1 include epidermodysplasia verruciformis, and acrodermatitis, and among its related super-pathways are Transmembrane transport of small molecules and Zinc transporters. GO annotations related to this gene include zinc ion transmembrane transporter activity and calcium channel inhibitor activity. An important paralog of this gene is SLC30A3.

UniProtKB/Swiss-Prot: ZNT1_HUMAN, Q9Y6M5
Function: May be involved in zinc transport out of the cell

Gene Wiki entry for SLC30A1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_167186.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC30A1 gene promoter:
         Egr-3   Sox5   Pax-5   FOXD3   CUTL1   FOXL1   AREB6   Pax-3   Sox9   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SLC30A1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC30A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.3   Ensembl cytogenetic band:  1q32.3   HGNC cytogenetic band: 1q32.3

SLC30A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC30A1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M211744:  view genomic region     (about GC identifiers)

Start:
211,744,910 bp from pter      End:
211,752,099 bp from pter
Size:
7,190 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZNT1_HUMAN, Q9Y6M5 (See protein sequence)
Recommended Name: Zinc transporter 1  
Size: 507 amino acids; 55300 Da
Subunit: Multimer (Probable)
Subcellular location: Cell membrane; Multi-pass membrane protein (Probable)
Secondary accessions: Q0VAK9 Q9BZF6

Explore the universe of human proteins at neXtProt for SLC30A1: NX_Q9Y6M5

Explore proteomics data for SLC30A1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y6M5

  • SLC30A1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC30A1 Protein Expression
    REFSEQ proteins: NP_067017.2  
    ENSEMBL proteins: 
     ENSP00000355968  
    Reactome Protein details: Q9Y6M5
    Human Recombinant Protein Products for SLC30A1: 
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    Novus Biologicals SLC30A1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SLC30A1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IEA--
    GO:0030315T-tubule ISS--

    SLC30A1 for ontologies           About GeneDecksing



    SLC30A1 Antibody Products: 
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    Assay Products for SLC30A1: 
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    Cloud-Clone Corp. CLIAs for SLC30A1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Zinc transporter 1 
    SLC30 zinc transporter family

    2 InterPro protein domains:
     IPR027469 Cation_efflux_TMD
     IPR002524 Cation_efflux

    Graphical View of Domain Structure for InterPro Entry Q9Y6M5

    ProtoNet protein and cluster: Q9Y6M5

    1 Blocks protein domain: IPB002524 Cation efflux protein

    UniProtKB/Swiss-Prot: ZNT1_HUMAN, Q9Y6M5
    Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily


    SLC30A1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZNT1_HUMAN, Q9Y6M5
    Function: May be involved in zinc transport out of the cell

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005385zinc ion transmembrane transporter activity IEA--
    GO:0008324cation transmembrane transporter activity ----
    GO:0019855calcium channel inhibitor activity ISS--
         
    SLC30A1 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Slc30a1):
     embryogenesis  mortality/aging  reproductive system 

    SLC30A1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC30A1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SLC30A1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC30A1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC30A1 

    miRNA
    Products:
        
    miRTarBase miRNAs that target SLC30A1:
    hsa-mir-155 (MIRT001501)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC30A1
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC30A1 (see all 13):
    hsa-miR-411* hsa-miR-892b hsa-miR-379* hsa-miR-548e hsa-miR-551b* hsa-miR-4294 hsa-miR-548a-3p hsa-miR-182
    SwitchGear 3'UTR luciferase reporter plasmidSLC30A1 3' UTR sequence
    Inhib. RNA
    Products:
        
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    OriGene RNAi products in human, mouse, rat for SLC30A1
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    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: SLC30A1 (NM_021194)
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC30A1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC30A1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1SLC-mediated transmembrane transport
    SLC-mediated transmembrane transport0.50
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    Transmembrane transport of small molecules0.50
    2Zinc transporters
    Zinc transporters0.68
    Zinc efflux and compartmentalization by the SLC30 family0.41
    Metal ion SLC transporters0.68
    3Mineral absorption
    Mineral absorption

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/6        Reactome Pathways for SLC30A1 (see all 6)
        Zinc efflux and compartmentalization by the SLC30 family
    SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Metal ion SLC transporters


    1         Kegg Pathway  (Kegg details for SLC30A1):
        Mineral absorption


    SLC30A1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC30A1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for SLC30A1 (Q9Y6M53 ENSP000003559684) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL37AP615133I2D: score=2 
    UBCENSP000003448184STRING: ENSP00000344818
    SPTLC1ENSP000002625544STRING: ENSP00000262554
    SLC30A10ENSP000003558934STRING: ENSP00000355893
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001701in utero embryonic development IEA--
    GO:0006812cation transport ----
    GO:0006829zinc ion transport ISS--
    GO:0006874cellular calcium ion homeostasis ISS--
    GO:0006882cellular zinc ion homeostasis ISS--

    SLC30A1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC30A1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC30A1 (ZNT1)

    3 Novoseek inferred chemical compound relationships for SLC30A1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    zinc 77.7 101 9560190 (4), 15378655 (4), 15451416 (3), 9521625 (3) (see all 32)
    cadmium 29.4 1 14568174 (1)
    calcium 14.8 12 17196651 (3), 19059322 (1), 17971132 (1), 19767393 (1) (see all 6)

    Search CenterWatch for drugs/clinical trials and news about SLC30A1 / ZNT1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC30A1 gene: 
    NM_021194.2  

    Unigene Cluster for SLC30A1:

    Solute carrier family 30 (zinc transporter), member 1
    Hs.519469  [show with all ESTs]
    Unigene Representative Sequence: BX647120
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000367001(uc001hio.1)

    miRNA
    Products:
         
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    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC30A1 (see all 13):
    hsa-miR-411* hsa-miR-892b hsa-miR-379* hsa-miR-548e hsa-miR-551b* hsa-miR-4294 hsa-miR-548a-3p hsa-miR-182
    SwitchGear 3'UTR luciferase reporter plasmidSLC30A1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC30A1
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    Primer
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    OriGene qPCR primer pairs and template standards for SLC30A1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC30A1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC30A1

    Additional mRNA sequence: 

    AB451467.1 AF364518.1 BC121015.1 BC121016.1 BX647120.1 

    3 DOTS entries:

    DT.456013  DT.75166694  DT.92422197 

    7 AceView cDNA sequences:

    AI621266 AI467909 AW079607 BE675653 AI804642 AW183618 AW195319 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC30A1 expression in normal human tissues (normalized intensities)      SLC30A1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGCTTTATG
    SLC30A1 Expression
    About this image


    SLC30A1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Hair (Integumentary System)
             mouse/organ system/integumental system   
     
     Tooth
             mouse/organ system/integumental system   
     
     Neural Tube (Nervous System)
             Telencephalon
     
     Brain (Nervous System)
             Cerebral Cortex

     -- (Nervous System)
             mouse/organ system/nervous system/central nervous system   

    See SLC30A1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC30A1

    SOURCE GeneReport for Unigene cluster: Hs.519469
        SABiosciences Custom PCR Arrays for SLC30A1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC30A1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC30A1 gene from 8/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc30a11 , 5 solute carrier family 30 (zinc transporter), member more1, 5 83.77(n)1
    86.23(a)1
      1 (97.01 cM)5
    227821  NM_009579.31  NP_033605.11 
     1919067675 
    chicken
    (Gallus gallus)
    Aves SLC30A11 solute carrier family 30 (zinc transporter), member more 70.52(n)
    65.51(a)
      421377  XM_419437.3  XP_419437.3 
    lizard
    (Anolis carolinensis)
    Reptilia SLC30A16
    SLC30A16
    Solute carrier family 30 member 1; Uncharacterized...
    solute carrier family 30 (zinc transporter), membe...
    60(a)
    25(a)
    possible ortholog
    1 ↔ 1
    1(238034214-238042154)
    AAWZ02037424(12988-16612)
    African clawed frog
    (Xenopus laevis)
    Amphibia slc30a1-prov2 solute carrier family 30 (zinc transporter), member more 77.9(n)    BC046675.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc775892 hypothetical protein MGC77589 76.07(n)   393853  BC063939.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta ZnT63C1 CG17723-PA 53.78(n)
    49.73(a)
      38407  NM_168016.1  NP_728857.1 
    worm
    (Caenorhabditis elegans)
    Secernentea cdf-11 Protein CDF-1 49.73(n)
    39.95(a)
      180923  NM_076694.3  NP_509095.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes COT11 Cot1p 47.45(n)
    37.7(a)
      854494   NP_014961.3 


    ENSEMBL Gene Tree for SLC30A1 (if available)
    TreeFam Gene Tree for SLC30A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC30A1 gene
    SLC30A32  SLC30A22  SLC30A82  SLC30A102  SLC30A42  
    1 SIMAP similar gene for SLC30A1 using alignment to 2 protein entries:     ZNT1_HUMAN (see all proteins):
    SLC30A10

    SLC30A1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/103 SNPs in SLC30A1 are shown (see all 103)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs75312771,2
    C,F--211747902(+) CTTATA/TTATTT 1 -- ds5001 ese36Minor allele frequency- T:0.15WA CSA NA EA 364
    rs1879059521,2
    --211747942(+) ATACCA/GATCTT 1 -- ds50010--------
    rs1921479351,2
    --211747943(+) TACCAA/GTCTTT 1 -- ds50010--------
    rs75198651,2
    C,F,A,H--211748118(+) TGCCCC/TATTGT 1 -- ds5001 ese320Minor allele frequency- T:0.19NA NS EA WA CSA 1444
    rs1822901621,2
    --211748335(+) AATTAA/TAATTC 1 -- ds50010--------
    rs1873231901,2
    --211748514(+) TCCAAA/GACAGT 1 -- ut310--------
    rs2017904871,2
    C--211748686(+) TCCTCC/TTGCAG 1 -- ut310--------
    rs2010497091,2
    --211748718(+) CACATC/GTTTTT 1 -- ut310--------
    rs1917334771,2
    C--211748792(+) AGGGAA/TGTTTT 2 I F mis10--------
    rs2004636481,2
    --211748819(+) GGGCTG/TCTTCT 2 K Q mis10--------

    HapMap Linkage Disequilibrium report for SLC30A1 (211744910 - 211752099 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SLC30A1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv832514CNV Loss17160897
    esv27192CNV Loss19812545
    nsv826542CNV Gain20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609521    OMIM disorders: --

    13 diseases for SLC30A1:    About MalaCards
    epidermodysplasia verruciformis    acrodermatitis    enteropathica    acrodermatitis enteropathica
    prostate cancer    ischemia    alzheimer's disease    hepatocellular carcinoma
    prostatitis    obesity    breast cancer    lung cancer
    neuronitis

    1 disease from the University of Copenhagen DISEASES database for SLC30A1:
    Epidermodysplasia verruciformis

    SLC30A1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    2 Novoseek inferred disease relationships for SLC30A1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    prostate cancer 25.6 1 14568174 (1)
    ischemia 0 1 10801948 (1)

    Genetic Association Database (GAD): SLC30A1
    Human Genome Epidemiology (HuGE) Navigator: SLC30A1 (4 documents)

    Export disorders for SLC30A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC30A1 gene, integrated from 9 sources (see all 66):
    (articles sorted by number of sources associating them with SLC30A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic susceptibility to distinct bladder cancer sub phenotypes. (PubMed id 19692168)1, 4 Guey L.T....Malats N. (2010)
    2. PTEN identified as important risk factor of chronic o bstructive pulmonary disease. (PubMed id 19625176)1, 4 Hosgood H.D....Lan Q. (2009)
    3. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PubMed id 19170196)1, 4 Shen M....Lan Q. (2009)
    4. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680)1, 4 Hosgood H.D....Lan Q. (2008)
    5. Correlation between atrial ZnT-1 expression and atrial fibrillation in humans: a pilot study. (PubMed id 17971132)1, 9 Etzion Y....Katz A. (2008)
    6. A role for ZnT-1 in regulating cellular cation influx. (PubMed id 15451416)1, 9 Segal D....Sekler I. (2004)
    7. Alterations in zinc transporter protein-1 (ZnT-1) in the brain of subjects with mild cognitive impairment, early, and late-stage Alzheimer's disease. (PubMed id 16179263)1, 9 Lovell M.A....Markesbery W.R. (2005)
    8. The involvement of ZnT-1, a new modulator of cardiac L-type calcium channels, in [corrected] atrial tachycardia remodeling. [correct ed] (PubMed id 20201890)1, 9 Beharier O....Moran A. (2010)
    9. Molecular basis for zinc transporter 1 action as an e ndogenous inhibitor of L-type calcium channels. (PubMed id 19767393)1, 9 Levy S....Moran A. (2009)
    10. Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses. (PubMed id 18158319)1, 9 Lazarczyk M....Favre M. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7779 HGNC: 11012 AceView: SLC30A1.1 Ensembl:ENSG00000170385 euGenes: HUgn7779
    ECgene: SLC30A1 Kegg: 7779 H-InvDB: SLC30A1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC30A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC30A1 gene:
    Search GeneIP for patents involving SLC30A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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