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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC2A8 Gene

protein-coding   GIFtS: 53
GCID: GC09P130159

solute carrier family 2 (facilitated glucose transporter),...

(Previous name: solute carrier family 2 (facilitated glucose transporter)...)
 Explore 6 diseases affiliated with
SLC2A8 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC2A8    

Aliases
for SLC2A8 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 81 2     Glucose Transporter Type X12 3
GLUT81 2 3 5     Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 81
GLUTX11 2 3     Solute Carrier Family 2, Facilitated Glucose Transporter Member 82
Glucose Transporter Type 82 3     GLUT-83

External Ids:    HGNC: 138121   Entrez Gene: 299882   Ensembl: ENSG000001368567   OMIM: 6052455   UniProtKB: Q9NY643   

Export aliases for SLC2A8 gene to outside databases

Previous GC identifers: GC09P121274 GC09P121806 GC09P123613 GC09P125535 GC09P127239 GC09P129199 GC09P099775


Summaries
for SLC2A8 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SLC2A8:
This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence
comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded
protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains
with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript
variants have been described for this gene. (provided by RefSeq, Nov 2012)

UniProtKB/Swiss-Prot: GTR8_HUMAN, Q9NY64
Function: Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner.
Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity)




Genomic Views
for SLC2A8 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC2A8 gene promoter:
         RP58   AP-1   HTF   NRSF form 1   MyoD   FOXD1   NRSF form 2   RORalpha1   AREB6   HOXA5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC2A8 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC2A8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC2A8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q33.3   Ensembl cytogenetic band:  9q33.3   HGNC cytogenetic band: 9q33.3

SLC2A8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC2A8 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P130159:  view genomic region     (about GC identifiers)

Start:
 130,159,421 bp from pter      End:
 130,170,703 bp from pter
Size:
 11,283 bases      Orientation:
 plus strand

Proteins
for SLC2A8 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: GTR8_HUMAN, Q9NY64 (See protein sequence)
Recommended Name: Solute carrier family 2, facilitated glucose transporter member 8  
Size: 477 amino acids; 50819 Da
Subunit: Interacts with AP2B1 (By similarity)
Subcellular location: Cell membrane; Multi-pass membrane protein (By similarity). Cytoplasmic vesicle membrane;
Multi-pass membrane protein (By similarity). Note=Principally intracellular. May move between intracellular vesicles
and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration (By
similarity)
Secondary accessions: Q8WUZ9 Q9NSC4

Explore the universe of human proteins at neXtProt for SLC2A8: NX_Q9NY64

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NY64

    • SLC2A8 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001258640.1  NP_001258641.1  NP_055395.2  

    ENSEMBL proteins: 
     ENSP00000362469   ENSP00000392434   ENSP00000411726   ENSP00000362450   ENSP00000362458  
     ENSP00000413973   ENSP00000404893   ENSP00000389070   ENSP00000391213  
    Reactome Protein details: Q9NY64
    Human Recombinant Protein Products: 
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    Novus Biologicals SLC2A8 Proteins
    Novus Biologicals SLC2A8 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SLC2A8

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane IEA--
    GO:0008021synaptic vesicle IEA--
    GO:0016021integral to membrane ----
    GO:0030659cytoplasmic vesicle membrane IEA--


    SLC2A8 for ontologies           About GeneDecksing



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    Uscn Antibodies for SLC2A8
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    Assay Products for SLC2A8: 
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    Uscn ELISAs and CLIAs for SLC2A8

    Protein Domains /
    Families
    for SLC2A8 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC2A8 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR005829 Sugar_transporter_CS
     IPR005828 Sub_transporter
     IPR003663 Sugar/inositol_transpt
     IPR020846 MFS_dom
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q9NY64

    ProtoNet protein and cluster: Q9NY64

    3 Blocks protein families:
    IPB000803 Mammalian facilitated glucose transporter family signature
    IPB003663 Sugar transporter signature
    IPB005829 Sugar transporter superfamily


    UniProtKB/Swiss-Prot: GTR8_HUMAN, Q9NY64
    Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter
    subfamily


    Function
    for SLC2A8 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: GTR8_HUMAN, Q9NY64
    Function: Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner.
    Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity)
    Induction: In testis, down-regulated by estrogen

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005355glucose transmembrane transporter activity IEA--
    GO:0005536glucose binding IEA--
    GO:0022857transmembrane transporter activity ----
    GO:0022891substrate-specific transmembrane transporter activity ----


    SLC2A8 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for SLC2A8: Slc2a8tm1.1Thor Slc2a8tm1.1Asch Slc2a8tm1Khm
         7 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Slc2a8):
     cardiovascular system  digestive/alimentary  growth/size  homeostasis/metabolism  mortality/aging 
     nervous system  reproductive system 

    SLC2A8 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for SLC2A8 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1SLC-mediated transmembrane transport
    		SLC-mediated transmembrane transport1.00
    		Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    		Transmembrane transport of small molecules0.50
    2Facilitative Na+-independent glucose transporters
    		Facilitative Na+-independent glucose transporters1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4        Reactome Pathways for SLC2A8
        SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Facilitative Na+-independent glucose transporters



    SLC2A8 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC2A8

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5 Interacting proteins for SLC2A8 (Q9NY643 ENSP000003624694) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AP1G1O437473I2D: score=1 
    AP2B1P630103I2D: score=1 
    LAMP1P112793I2D: score=1 
    LAMP2P134733I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001666response to hypoxia IEA--
    GO:0005975carbohydrate metabolic process TAS10671487
    GO:0007141male meiosis I IEA--
    GO:0008286insulin receptor signaling pathway IEA--
    GO:0008643carbohydrate transport ----


    SLC2A8 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC2A8 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC2A8 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC2A8
    1 Novoseek chemical compound relationship for SLC2A8 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glucose 43 23 10821868 (4), 11689004 (3), 15488990 (3), 11845330 (2) (see all 7)

    Search CenterWatch for drugs/clinical trials and news about SLC2A8 / GTR8 

    Transcripts
    for SLC2A8 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC2A8 gene (3 alternative transcripts): 
    NM_001271711.1  NM_001271712.1  NM_014580.4  

    Unigene Cluster for SLC2A8:

    Solute carrier family 2 (facilitated glucose transporter), member 8
    Hs.179522  [show with all ESTs]
    Unigene Representative Sequence: NM_014580
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373371(uc004bqu.3 uc010mxj.3) ENST00000451404 ENST00000476835
    ENST00000419917 ENST00000373352 ENST00000373360 ENST00000419132 ENST00000439597
    ENST00000423934 ENST00000430147 ENST00000484617 ENST00000489239 ENST00000477027
    ENST00000485806 ENST00000484208

    miRNA
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    hsa-miR-182 hsa-miR-185* hsa-miR-29a* hsa-miR-1271 hsa-miR-96
    SwitchGear 3'UTR luciferase reporter plasmid: SLC2A8 3' UTR sequence
    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AF289587.1 AJ245937.1 BC019043.2 NR_073416.1 Y17801.1 

    15 DOTS entries:

    DT.95276690  DT.113798  DT.92424096  DT.105642  DT.97819608  DT.95276688  DT.121163316  DT.100773111 
    DT.75159838  DT.95276682  DT.95276684  DT.40248217  DT.95276687  DT.100676293  DT.92424094 

    24/117 AceView cDNA sequences (see all 117):

    BF940419 AW248655 CB218134 BM545247 CA306503 CR625717 BQ773697 BI831086 
    NM_014580 BF732259 BI752171 BC019043 AI818661 BQ011294 BE261639 CA423844 
    AI971919 AI628848 BU684780 BI334832 BQ028209 BU626294 AL534131 AI094911 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for SLC2A8 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12a · 12b
    SP1:                                -           -     -                 -                                                               
    SP2:                          -     -     -     -     -           -     -                                                               
    SP3:                          -     -     -     -     -                 -                                                               
    SP4:                                                                    -     -                                                         
    SP5:                                                                    -                                                               


    ECgene alternative splicing isoforms for SLC2A8

    Expression
    for SLC2A8 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC2A8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CGCAAGACTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SLC2A8 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ progenitor W8 (Embryonic Progenitor Cell)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SLC2A8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC2A8

    SOURCE GeneReport for Unigene cluster: Hs.179522

    UniProtKB/Swiss-Prot: GTR8_HUMAN, Q9NY64
    Tissue specificity: Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other
    tissues

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    In Situ
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    Orthologs
    for SLC2A8 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC2A8 gene from 6/22 species (see all 22)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SLC2A81 solute carrier family 2 (facilitated glucose transporter), more 60.47(n)
    60.26(a)    		   378802  NM_204375.1  NP_989706.1 
    lizard
    (Anolis carolinensis)    		 Reptilia SLC2A86
    		 --
    		 60(a)
    		 1 ↔ 1
    		 GL344796.1(2909-16660)
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.174292 Danio rerio cDNA clone MGC56364 IMAGE5604396, complete more 74.87(n)    BC049409.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG82343
    Tret1-11    		 fructose transporter3
    Trehalose transporter 1-11    		 38(a)
    (best of 8)3
    49.03(n)1
    39.91(a)1    		   362481  NM_136849.11  NP_610693.11 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT1G194501 sugar transporter ERD6-like 4 45.74(n)
    41.16(a)    		   838529  NM_101801.2  NP_173377.1 
    rice
    (Oryza sativa)    		 Liliopsida Os05g05790001 hypothetical protein 49.18(n)
    39.76(a)    		   4339710  NM_001062951.1  NP_001056416.1 


    ENSEMBL Gene Tree for SLC2A8 (if available)
    TreeFam Gene Tree for SLC2A8 (if available) 

    Paralogs
    for SLC2A8 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC2A8 gene
    SLC2A62  
    7 SIMAP similar genes for SLC2A8 using alignment to 10 protein entries:     GTR8_HUMAN (see all proteins):
    SLC2A10    SLC2A6    SLC2A2    SLC2A1    SLC2A14    SLC2A3
    SLC2A7

    SLC2A8 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC2A8 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/230 NCBI SNPs in SLC2A8 are shown (see all 230)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1852854181,2
    		--130157521(+) CCCCAC/TGTCTG 4 -- us2k10--------
    rs1164780881,2
    		F,--130157530(+) TGCCAT/CGCAGA 4 -- us2k11Minor allele frequency- C:0.06WA 118
    rs1912275221,2
    		--130157549(+) CAGTGC/TCTTGT 4 -- us2k10--------
    rs38088401,2
    		C,H--130157727(-) AATTGT/CGGGTG 4 -- us2k16Minor allele frequency- C:0.00NS EA NA 422
    rs38088391,2
    		C,F,H,--130157777(-) TCCACC/GTCTTG 4 -- us2k119Minor allele frequency- G:0.17EA NS NA WA 3370
    rs1162609391,2
    		F,--130157906(+) CCATCG/AGCCAC 4 -- us2k11Minor allele frequency- A:0.03WA 118
    rs38088381,2
    		C,F,A,H,--130157934(-) GATTAT/CGTAGG 4 -- us2k124Minor allele frequency- C:0.24EA NS NA 3854
    rs1836408161,2
    		--130158069(+) TCCATA/TGGGGG 4 -- us2k10--------
    rs1886864961,2
    		--130158081(+) AGGACA/GGAAGT 4 -- us2k10--------
    rs1928310121,2
    		--130158122(+) CTGTGA/GTAAGA 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for SLC2A8 (130159421 - 130170703 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SLC2A8: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for SLC2A8 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC2A8 for disorders           About GeneDecksing

    OMIM gene information: 605245    OMIM disorders: --

    6 diseases for SLC2A8:    About MalaCards
    prostate cancer    hypoxia    prostatitis    adenocarcinoma
    neuronitis    carcinoma

    Human Genome Epidemiology (HuGE) Navigator: SLC2A8 (1 document)

    Export disorders for SLC2A8 gene to outside databases

    Publications
    for SLC2A8 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC2A8 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with SLC2A8)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. GLUT8, a novel member of the sugar transport facilitator family with glucose transport activity. (PubMed id 10821868)1, 2, 3, 9 Doege H.... Joost H.-G. (2000)
    2. GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues. (PubMed id 10671487)1, 2, 3 Ibberson M.R.... Thorens B. (2000)
    3. The glucose transport facilitator GLUT8 is predominantly associated with the acrosomal region of mature spermatozoa. (PubMed id 11845330)1, 9 Schurmann A....Joost H.G. (2002)
    4. Multiple myeloma exhibits novel dependence on GLUT4, G LUT8, and GLUT11: implications for glucose transporter-directed therapy. (PubMed id 22452979)1 McBrayer S.K....Shanmugam M. (2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    7. Genetic variability of the fatty acid synthase pathwa y is not associated with prostate cancer risk in the European Prospective Inves tigation on Cancer (EPIC). (PubMed id 20965718)1 Campa D....Canzian F. (2010)
    8. GLUT8, the enigmatic intracellular hexose transporter. (PubMed id 19176349)1 Schmidt S....Schurmann A. (2009)
    9. Expression of hexokinases and glucose transporters in treated and untreated oesophageal adenocarcinoma. (PubMed id 19554504)1 Fonteyne P....Van de Wiele C. (2009)
    10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)

    External Searches for SLC2A8 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SLC2A8 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29988 HGNC: 13812 AceView: SLC2A8 Ensembl:ENSG00000136856 euGenes: HUgn29988
    ECgene: SLC2A8 H-InvDB: SLC2A8

    Other Databases showing SLC2A8 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC2A8 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC2A8 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC2A8 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC2A8 gene:
    Search GeneIP for patents involving SLC2A8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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