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SLC2A6 Gene

protein-coding   GIFtS: 59
GCID: GC09M136336

Solute Carrier Family 2 (Facilitated Glucose Transporter),...

  See SLC2A6-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 61 2     GLUT92 3
Glucose Transporter Type 62 3     GLUT62
Glucose Transporter Type 92 3     HSA0113722
GLUT-62 3     Solute Carrier Family 2, Facilitated Glucose Transporter Member 62
GLUT-92 3     

External Ids:    HGNC: 110111   Entrez Gene: 111822   Ensembl: ENSG000001603267   OMIM: 6068135   UniProtKB: Q9UGQ33   

Export aliases for SLC2A6 gene to outside databases

Previous GC identifers: GC09M127425 GC09M127893 GC09M129689 GC09M131612 GC09M133366 GC09M135326 GC09M105837


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC2A6 Gene:
Hexose transport into mammalian cells is catalyzed by a family of membrane proteins, including SLC2A6, that
contain 12 transmembrane domains and a number of critical conserved residues.(supplied by OMIM, Jul 2002)

GeneCards Summary for SLC2A6 Gene:
SLC2A6 (solute carrier family 2 (facilitated glucose transporter), member 6) is a protein-coding gene. Diseases associated with SLC2A6 include testis seminoma. GO annotations related to this gene include glucose transmembrane transporter activity. An important paralog of this gene is SLC2A8.

UniProtKB/Swiss-Prot: GTR6_HUMAN, Q9UGQ3
Function: Facilitative glucose transporter; binds cytochalasin B with low affinity

Gene Wiki entry for SLC2A6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NT_008470.20  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC2A6 gene promoter:
         AML1a   Lmo2   LCR-F1   GATA-2   c-Ets-1   E2F-1   E2F   FOXO1a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC2A6 promoter sequence
   Search Chromatin IP Primers for SLC2A6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC2A6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34   Ensembl cytogenetic band:  9q34.2   HGNC cytogenetic band: 9q34

SLC2A6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC2A6 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M136336:  view genomic region     (about GC identifiers)

Start:
136,336,216 bp from pter      End:
136,344,276 bp from pter
Size:
8,061 bases      Orientation:
minus strand

1 alternative location:
Chr9-,NW_003315925 297,188-305,248     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: GTR6_HUMAN, Q9UGQ3 (See protein sequence)
Recommended Name: Solute carrier family 2, facilitated glucose transporter member 6  
Size: 507 amino acids; 54539 Da
Caution: Has been described as GLUT9 in literature, but this gene name has already been used for SLC2A9
Secondary accessions: A6NNU6 Q5SXD7 Q8NCC2
Alternative splicing: 2 isoforms:  Q9UGQ3-1   Q9UGQ3-2   

Explore the universe of human proteins at neXtProt for SLC2A6: NX_Q9UGQ3

Explore proteomics data for SLC2A6 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn370
  • Modification sites at PhosphoSitePlus

  • See SLC2A6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001138571.1  NP_060055.2  

    ENSEMBL proteins: 
     ENSP00000360964   ENSP00000360966   ENSP00000405124   ENSP00000398004  
    Reactome Protein details: Q9UGQ3

    SLC2A6 Human Recombinant Protein Products:

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    antibodies-online peptides for SLC2A6

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Glucose transporter 6
    Class II transporters

    5 InterPro protein domains:
     IPR005829 Sugar_transporter_CS
     IPR005828 Sub_transporter
     IPR003663 Sugar/inositol_transpt
     IPR020846 MFS_dom
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q9UGQ3

    ProtoNet protein and cluster: Q9UGQ3

    3 Blocks protein domains:
    IPB000803 Mammalian facilitated glucose transporter family signature
    IPB003663 Sugar transporter signature
    IPB005829 Sugar transporter superfamily


    UniProtKB/Swiss-Prot: GTR6_HUMAN, Q9UGQ3
    Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose
    transporter subfamily


    Find genes that share domains with SLC2A6           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GTR6_HUMAN, Q9UGQ3
    Function: Facilitative glucose transporter; binds cytochalasin B with low affinity

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005355glucose transmembrane transporter activity NAS10970791
    GO:0022857transmembrane transporter activity ----
    GO:0022891substrate-specific transmembrane transporter activity ----
         
    Find genes that share ontologies with SLC2A6           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC2A6:
     Decreased homologous recombina 

    Animal Models:
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    miRNA
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    4 qRT-PCR Assays for microRNAs that regulate SLC2A6:
    hsa-miR-3176 hsa-miR-1914 hsa-miR-3918 hsa-miR-3922-3p
    SwitchGear 3'UTR luciferase reporter plasmidSLC2A6 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GTR6_HUMAN, Q9UGQ3: Cell membrane; Multi-pass membrane protein (By similarity). Note=The dileucine
    internalization motif is critical for intracellular sequestration (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    endoplasmic reticulum1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016020membrane NAS10970791
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with SLC2A6           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SLC2A6 About    
    See pathways by source

    SuperPathContained pathways About
    1Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    SLC-mediated transmembrane transport0.47
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    Transmembrane transport of small molecules0.47
    Facilitative Na+-independent glucose transporters0.00
    2PAK Pathway
    Antioxidant Action of Vitamin-C0.56
    3HIF1Alpha Pathway
    HIF1Alpha Pathway


    Find genes that share SuperPaths with SLC2A6           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for SLC2A6
        Antioxidant Action of Vitamin-C
    HIF1Alpha Pathway


    1 Reactome Pathway for SLC2A6
        Facilitative Na+-independent glucose transporters


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC2A6
    Interactions:

        Search GeneGlobe Interaction Network for SLC2A6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    Selected Interacting proteins for SLC2A6 (ENSP000003609664) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    UBBENSP000003046974STRING: ENSP00000304697
    LAMP1ENSP000003332984STRING: ENSP00000333298
    LAMP2ENSP000004084114STRING: ENSP00000408411
    AP1G1ENSP000003771484STRING: ENSP00000377148
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015758glucose transport NAS10970791
    GO:0055085transmembrane transport TAS--

    Find genes that share ontologies with SLC2A6           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
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    Browse Tocris compounds for SLC2A6 (GTR6)

    Selected Novoseek inferred chemical compound relationships for SLC2A6 gene (see all 11)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glucose 59.9 21 19797240 (2), 1695905 (2), 11848285 (1), 12596094 (1) (see all 16)
    cytochalasin b 59 1 8168538 (1)
    fructose 58.5 4 19797240 (1), 12668090 (1), 9299540 (1), 11050206 (1)
    monosaccharide 56.2 1 19704840 (1)
    xylose 54.8 1 2040626 (1)
    lactose 53.5 1 10449337 (1)
    polysaccharide 33.7 1 20162350 (1)
    citrate 14.4 1 1970645 (1)
    tetracycline 12.6 1 1970645 (1)
    proline 11.2 2 10987651 (1), 2172229 (1)



    Find genes that share compounds with SLC2A6           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SLC2A6 gene (2 alternative transcripts): 
    NM_001145099.1  NM_017585.3  

    Unigene Cluster for SLC2A6:

    Solute carrier family 2 (facilitated glucose transporter), member 6
    Hs.244378  [show with all ESTs]
    Unigene Representative Sequence: AK096630
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371897 ENST00000485978 ENST00000371899(uc004cee.3 uc004cef.3 uc004ceg.3 uc011mdj.1)
    ENST00000432868 ENST00000414172
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    Additional mRNA sequence: 

    AJ011372.2 AK074836.1 AK074927.1 AK096630.1 AK222919.1 AK225106.1 AK294974.1 BC013740.1 
    Y17803.1 

    11 DOTS entries:

    DT.40219080  DT.100772809  DT.100682834  DT.100024074  DT.100644976  DT.121151878  DT.102823393  DT.121151730 
    DT.121152080  DT.100649936  DT.100772811 

    Selected AceView cDNA sequences (see all 60):

    BU857349 AI927723 BU195878 NM_017585 AK074836 AI886975 BU838134 Y17803 
    AJ011372 CA305966 BP354243 BU789540 AK074927 BC013740 BG119668 BU552447 
    BX458506 BU789810 BI837987 BQ943572 BU153379 BE260472 BF311508 BU859979 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SLC2A6 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11
    SP1:                          -                       -     -                                                                       -     -         
    SP2:                          -                       -     -                                                           -           -     -         
    SP3:                                                  -     -                                                                       -     -         
    SP4:                          -                       -     -           -     -                                                                     
    SP5:                                                  -     -                                                                                       


    ECgene alternative splicing isoforms for SLC2A6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC2A6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCCGCAGGA
    SLC2A6 Expression
    About this image

    SLC2A6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC2A6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.244378

    UniProtKB/Swiss-Prot: GTR6_HUMAN, Q9UGQ3
    Tissue specificity: Highly expressed in brain, spleen and peripheral blood leukocytes

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC2A6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC2A6 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc2a61 , 5 solute carrier family 2 (facilitated glucose transporter), more1, 5 82.76(n)1
    83.64(a)1
      2 (19.18 cM)5
    2276591  NM_172659.21  NP_766247.21 
     270213635 
    chicken
    (Gallus gallus)
    Aves SLC2A61 solute carrier family 2 (facilitated glucose transporter), more 68.77(n)
    66.47(a)
      425954  XM_004945944.1  XP_004946001.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC2A66
    solute carrier family 2 (facilitated glucose trans...
    60(a)
    1 ↔ 1
    GL344898.1(230-8954)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia slc2a61 solute carrier family 2 (facilitated glucose transporter), more 61.84(n)
    59.47(a)
      100485956  XM_002942917.2  XP_002942963.2 
    zebrafish
    (Danio rerio)
    Actinopterygii slc2a61 solute carrier family 2 (facilitated glucose transporter), more 58.46(n)
    57.02(a)
      560602  XM_684000.6  XP_689092.6 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG82343
    Tret1-11
    fructose transporter3
    Trehalose transporter 1-11
    32(a)
    (best of 8)3
    48.23(n)1
    34.56(a)1
      362481  NM_136849.11  NP_610693.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes HXT26
    HXT56
    (see all 20)
    High-affinity glucose transporter of the major fac...
    Hexose transporter with moderate affinity for gluc...
    (see all 20)
    21(a)
    20(a)
    (see all 20)
    many ↔ many
    many ↔ many
    (see all 20)
    XIII(288079-289704) YMR011W
    VIII(294669-296447) YHR096C


    ENSEMBL Gene Tree for SLC2A6 (if available)
    TreeFam Gene Tree for SLC2A6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC2A6 gene
    SLC2A82  
    1 SIMAP similar gene for SLC2A6 using alignment to 3 protein entries:     GTR6_HUMAN (see all proteins):
    SLC2A8

    Find genes that share paralogs with SLC2A6           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC2A6 (see all 281)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1507195591,2
    C--136336442(+) CTCCCA/GGGTTC 2 -- ut310--------
    rs1155656241,2
    F--136336496(+) GTGTGC/TCACCA 2 -- ut311Minor allele frequency- T:0.03WA 118
    rs1907153611,2
    --136336571(+) AACTCC/TTGGCC 2 -- ut310--------
    rs1127632911,2
    C--136336624(+) ACAGGC/TGTGAG 2 -- ut311Minor allele frequency- T:0.50WA 2
    rs1390055131,2
    --136336636(+) CACTGA/TGCCCG 2 -- ut310--------
    rs784427991,2
    C,F--136336708(+) AAAGCC/TGGGTC 2 -- ut311Minor allele frequency- T:0.02EA 120
    rs1424715421,2
    --136336723(+) TTGCAC/TAGCCA 2 -- ut310--------
    rs1459801451,2
    C--136336739(+) CACCAA/GATCAG 2 -- ut310--------
    rs1866243301,2
    --136336794(+) CCTCTC/TAGTCC 2 -- ut310--------
    rs413074281,2
    C,F--136336804(+) CTCCCC/TGTAGC 2 -- ut311Minor allele frequency- T:0.05NA 120

    HapMap Linkage Disequilibrium report for SLC2A6 (136336216 - 136344276 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for SLC2A6:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2739138CNV Deletion23290073
    nsv894096CNV Loss21882294
    nsv894081CNV Loss21882294
    dgv8330n71CNV Loss21882294
    nsv894097CNV Loss21882294
    dgv8328n71CNV Loss21882294
    dgv8325n71CNV Loss21882294
    nsv894094CNV Loss21882294
    nsv894086CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC2A6
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC2A6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606813    OMIM disorders: --

    1 disease for SLC2A6:    
    About MalaCards
    testis seminoma

    3 diseases from the University of Copenhagen DISEASES database for SLC2A6:
    Gout     Hyperuricemia     Testis seminoma

    Find genes that share disorders with SLC2A6           About GenesLikeMe

    2 Novoseek inferred disease relationships for SLC2A6 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 1 16523487 (1)
    cancer 0 2 15229399 (1), 16523487 (1)

    Genetic Association Database (GAD): SLC2A6
    Human Genome Epidemiology (HuGE) Navigator: SLC2A6 (2 documents)

    Export disorders for SLC2A6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC2A6 gene, integrated from 10 sources (see all 81):
    (articles sorted by number of sources associating them with SLC2A6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes. (PubMed id 10970791)1, 2, 3 Doege H.... Schuermann A. (Biochem. J. 2000)
    2. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)1, 4 He C....Hunter D.J. (Hum. Genet. 2010)
    3. Association between GLUT9 and gout in Japanese men. (PubMed id 20413573)1, 4 Urano W....Yamanaka H. (Ann. Rheum. Dis. 2010)
    4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin. (PubMed id 19729612)4 Paterson A.D....Bull S.B. (Arterioscler. Thromb. Vasc. Biol. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 11182 HGNC: 11011 AceView: SLC2A6 Ensembl:ENSG00000160326 euGenes: HUgn11182
    ECgene: SLC2A6 H-InvDB: SLC2A6

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SLC2A6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for SLC2A6 gene:
    Search GeneIP for patents involving SLC2A6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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