Aliases for SLC2A5 Gene
External Ids for SLC2A5 Gene
Previous HGNC Symbols for SLC2A5 Gene
Previous GeneCards Identifiers for SLC2A5 Gene
GeneCards Summary for SLC2A5 Gene
SLC2A5 (Solute Carrier Family 2 Member 5) is a Protein Coding gene. Diseases associated with SLC2A5 include Testis Seminoma and Testicular Malignant Germ Cell Cancer. Among its related pathways are Glycosaminoglycan metabolism and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include transmembrane transporter activity and glucose transmembrane transporter activity. An important paralog of this gene is ENSG00000251357.
UniProtKB/Swiss-Prot for SLC2A5 Gene
Functions as a fructose transporter that has only low activity with other monosaccharides (PubMed:8333543). Can mediate the uptake of 2-deoxyglucose, but with low efficiency (PubMed:1695905). Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake (By similarity).