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SLC2A4RG Gene

protein-coding   GIFtS: 51
GCID: GC20P062369

SLC2A4 Regulator

  See SLC2A4RG-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
SLC2A4 Regulator1 2     HDBP12 3
GLUT4 Enhancer Factor1 2 3     Si-1-22
Huntington'S Disease Gene Regulatory Region-Binding Protein 11 2     Si-1-2-192
GEF2 3     Huntington Disease Gene Regulatory Region-Binding Protein 13
HDBP-12 3     

External Ids:    HGNC: 159301   Entrez Gene: 567312   Ensembl: ENSG000001255207   OMIM: 6094935   UniProtKB: Q9NR833   

Export aliases for SLC2A4RG gene to outside databases

Previous GC identifers: GC20P062248 GC20P063050 GC20P063097 GC20P061841 GC20P059104


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC2A4RG Gene:
The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute
carrier family 2 member 4 gene. The encoded protein interacts with another transcription factor, myocyte enhancer
factor 2, to activate transcription of this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for SLC2A4RG Gene:
SLC2A4RG (SLC2A4 regulator) is a protein-coding gene. Diseases associated with SLC2A4RG include huntington's disease. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF704.

UniProtKB/Swiss-Prot: S2A4R_HUMAN, Q9NR83
Function: Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence
5'-GCCGGCG-3'

Gene Wiki entry for SLC2A4RG Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000020.10  NC_018931.2  NT_011362.11  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC2A4RG gene promoter:
         AhR   NF-1   AML1a   NRSF form 1   Cart-1   NRSF form 2   Ik-1   GATA-2   Arnt   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC2A4RG promoter sequence
   Search Chromatin IP Primers for SLC2A4RG

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC2A4RG


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.33   Ensembl cytogenetic band:  20q13.33   HGNC cytogenetic band: 20q13.33

SLC2A4RG Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC2A4RG gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P062369:  view genomic region     (about GC identifiers)

Start:
62,371,211 bp from pter      End:
62,375,403 bp from pter
Size:
4,193 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: S2A4R_HUMAN, Q9NR83 (See protein sequence)
Recommended Name: SLC2A4 regulator  
Size: 387 amino acids; 41267 Da
Subunit: Interacts with MEF2A
Sequence caution: Sequence=AAH17446.1; Type=Erroneous initiation; Sequence=BAD29732.1; Type=Erroneous initiation;
Secondary accessions: Q6F6I6 Q6F6I7 Q6GTK5 Q8TAH5 Q8WVW7 Q96QD3 Q9BV85
Alternative splicing: 2 isoforms:  Q9NR83-1   Q9NR83-2   (Incomplete sequence)

Explore the universe of human proteins at neXtProt for SLC2A4RG: NX_Q9NR83

Explore proteomics data for SLC2A4RG at MOPED


See SLC2A4RG Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_064446.2  
ENSEMBL proteins: 
 ENSP00000266077  

SLC2A4RG Human Recombinant Protein Products:

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antibodies-online proteins for SLC2A4RG (2 products) 

 
antibodies-online peptides for SLC2A4RG

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antibodies-online kits for SLC2A4RG (2 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro protein domains:
 IPR015880 Znf_C2H2-like
 IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q9NR83

ProtoNet protein and cluster: Q9NR83

UniProtKB/Swiss-Prot: S2A4R_HUMAN, Q9NR83
Similarity: Contains 1 C2H2-type zinc finger


Find genes that share domains with SLC2A4RG           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: S2A4R_HUMAN, Q9NR83
Function: Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence
5'-GCCGGCG-3'

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003677DNA binding IEA--
GO:0003700sequence-specific DNA binding transcription factor activity TAS10825161
GO:0046872metal ion binding IEA--
     
Find genes that share ontologies with SLC2A4RG           About GenesLikeMe


Phenotypes:
     1 GenomeRNAi human phenotype for SLC2A4RG:
 Decreased viability with pacli 

Animal Models:
   genOway: Develop your customized and physiologically relevant rodent model for SLC2A4RG

miRNA
Products:
    
miRTarBase miRNAs that target SLC2A4RG:
hsa-mir-744-5p (MIRT037461), hsa-mir-124-3p (MIRT022491), hsa-mir-26b-5p (MIRT029272)

Block miRNA regulation of human, mouse, rat SLC2A4RG using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate SLC2A4RG (see all 41):
hsa-miR-576-3p hsa-miR-301a hsa-miR-449a hsa-miR-519a hsa-miR-29b-1* hsa-miR-649 hsa-miR-3622b-3p hsa-miR-3613-3p
SwitchGear 3'UTR luciferase reporter plasmidSLC2A4RG 3' UTR sequence
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat SLC2A4RG

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GenScript: all cDNA clones in your preferred vector: SLC2A4RG (NM_020062)
Browse Sino Biological Human cDNA Clones
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC2A4RG

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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC2A4RG


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
S2A4R_HUMAN, Q9NR83: Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus5
cytosol2

Gene Ontology (GO): 3 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus NAS10825161
GO:0005730NOT nucleolus IDA--
GO:0005737cytoplasm IEA--

Find genes that share ontologies with SLC2A4RG           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for SLC2A4RG About    
See pathways by source

SuperPathContained pathways About
1AMPK signaling
AMPK signaling


1 BioSystems Pathway for SLC2A4RG
    AMPK signaling


    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC2A4RG
Interactions:

    GeneGlobe Interaction Network for SLC2A4RG

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for SLC2A4RG (Q9NR833 ENSP000002660774) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
HDAC5Q9UQL63, ENSP000002259834I2D: score=1 STRING: ENSP00000225983
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006351transcription, DNA-templated IEA--
GO:0006355regulation of transcription, DNA-templated TAS10825161

Find genes that share ontologies with SLC2A4RG           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for SLC2A4RG (S2A4R)

1 Novoseek inferred chemical compound relationship for SLC2A4RG gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
glucose 43.8 4 18245850 (1), 16620308 (1)



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(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for SLC2A4RG gene: 
NM_020062.3  

Unigene Cluster for SLC2A4RG:

SLC2A4 regulator
Hs.435126  [show with all ESTs]
Unigene Representative Sequence: NM_020062
8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000266077(uc002ygq.3 uc002ygr.3 uc011abj.2) ENST00000474248
ENST00000485897 ENST00000493772(uc002ygs.3) ENST00000491109 ENST00000473157
ENST00000482718 ENST00000496425
miRNA
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Block miRNA regulation of human, mouse, rat SLC2A4RG using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate SLC2A4RG (see all 41):
hsa-miR-576-3p hsa-miR-301a hsa-miR-449a hsa-miR-519a hsa-miR-29b-1* hsa-miR-649 hsa-miR-3622b-3p hsa-miR-3613-3p
SwitchGear 3'UTR luciferase reporter plasmidSLC2A4RG 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for SLC2A4RG
Predesigned siRNA for gene silencing in human, mouse, rat SLC2A4RG
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OriGene clones in human, mouse for SLC2A4RG (see all 6)
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GenScript: all cDNA clones in your preferred vector: SLC2A4RG (NM_020062)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC2A4RG
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC2A4RG
Primer
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OriGene qPCR primer pairs and template standards for SLC2A4RG
OriGene qSTAR qPCR primer pairs in human, mouse for SLC2A4RG
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat SLC2A4RG
  QuantiTect SYBR Green Assays in human, mouse, rat SLC2A4RG
  QuantiFast Probe-based Assays in human, mouse, rat SLC2A4RG

Additional mRNA sequence: 

AB044777.1 AB044786.1 AB052777.1 AF249267.3 AK298304.1 BC001402.2 BC017446.1 BC028349.2 
BC052306.1 

16 DOTS entries:

DT.100782599  DT.109291  DT.97803346  DT.75185917  DT.446689  DT.120825070  DT.40255572  DT.95251585 
DT.100782598  DT.91725069  DT.92432195  DT.120824958  DT.100038066  DT.100822146  DT.97847663  DT.97847666 

Selected AceView cDNA sequences (see all 291):

AI817998 AA302255 BM974581 CR626338 BM916471 AK000413 CR595933 BC028349 
CR616647 CD722647 BM423669 BQ673062 BM846083 AA328684 NM_017806 BQ054133 
BC017446 CB156612 BF337599 BC019338 NM_020062 BM912404 AI261465 AW192357 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for SLC2A4RG (see all 7)    About this scheme

ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c
SP1:                          -     -                                                                                 
SP2:                                                                          -     -     -                           
SP3:                          -     -                                                                                 
SP4:                                                                                                                  
SP5:                                                                                                                  


ECgene alternative splicing isoforms for SLC2A4RG

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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SLC2A4RG expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TTTGTTTTTG
SLC2A4RG Expression
About this image

SLC2A4RG Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

SLC2A4RG Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.435126

UniProtKB/Swiss-Prot: S2A4R_HUMAN, Q9NR83
Tissue specificity: According to PubMed:14630949, expressed in heart, skeletal muscle, liver, kidney and pancreas;
undetectable in lung, placenta or brain. According to PubMed:14625278, ubiquitously expressed, with lowest
expression in brain and ileum

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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC2A4RG

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for SLC2A4RG gene from Selected species (see all 9)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Slc2a4rg-ps5 Slc2a4 regulator, pseudogene   --   2 (103.63 cM) 181384250 
chicken
(Gallus gallus)
Aves SLC2A4RG6
SLC2A4 regulator
46(a)
1 ↔ 1
20(9958400-9961363)
lizard
(Anolis carolinensis)
Reptilia SLC2A4RG6
SLC2A4 regulator
42(a)
1 ↔ 1
4(156455858-156476054)
zebrafish
(Danio rerio)
Actinopterygii SLC2A4RG6
SLC2A4 regulator
32(a)
1 ↔ 1
23(14702946-14843882) ENSDARG00000077762
fruit fly
(Drosophila melanogaster)
Insecta Glut4EF6
Glucose transporter 4 enhancer factor
11(a)
1 → many
3R(5700403-5821086)


ENSEMBL Gene Tree for SLC2A4RG (if available)
TreeFam Gene Tree for SLC2A4RG (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for SLC2A4RG gene
ZNF7042  ZNF3952  
2 SIMAP similar genes for SLC2A4RG using alignment to 1 protein entry:     S2A4R_HUMAN:
Si-1-2-19    ZNF704

Find genes that share paralogs with SLC2A4RG           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for SLC2A4RG (see all 131)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 20 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs30326801,2
C--62369439(+) ggcggGGGCGG/-
        
ccggg
1 -- cds1 tfbs31Minor allele frequency- -:0.00NA 2
rs60110711,2
C,F--62372005(+) CACCCC/GCAAGC 1 -- int11Minor allele frequency- G:0.21WA 118
rs17417081,2
C,F,A,H--62372041(+) GAAATG/TATCGA 1 -- int120Minor allele frequency- T:0.24NS EA NA 2404
rs1859741691,2
--62372096(+) CTAGAG/TCTCAG 1 -- int10--------
rs60625101,2
C,F,A,H--62372148(+) TGCGCC/GGTCGG 1 -- int17Minor allele frequency- G:0.38NA CSA WA EA 365
rs60106361,2
C,F,A--62372456(+) GCCCAG/ACCCCA 1 -- int14Minor allele frequency- A:0.30NA CSA WA 124
rs1493147081,2
--62372653(+) CTGCAC/TGTGGA 1 -- int10--------
rs48092211,2
C,F--62372706(+) ACCCCA/GCCCCC 1 -- int1 ese39Minor allele frequency- G:0.34NA WA CSA EA EU 856
rs1902449641,2
C--62372711(+) GCCCCC/TATCTC 1 -- int10--------
rs1443009421,2
F--62372743(+) AGCCCG/TGCTGG 2 R L mis11Minor allele frequency- T:0.00NA 4508

HapMap Linkage Disequilibrium report for SLC2A4RG (62371211 - 62375403 bp)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for SLC2A4RG (see all 27):    About this table    
Variant IDTypeSubtypePubMed ID
esv2722959CNV Deletion23290073
nsv913250CNV Loss21882294
dgv4647n71CNV Loss21882294
dgv4644n71CNV Loss21882294
dgv4649n71CNV Loss21882294
dgv4645n71CNV Loss21882294
nsv913213CNV Loss21882294
dgv4618n71CNV Loss21882294
nsv913256CNV Loss21882294
dgv4651n71CNV Loss21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing SLC2A4RG
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 609493    OMIM disorders: --

1 disease for SLC2A4RG:    
About MalaCards
huntington's disease


Find genes that share disorders with SLC2A4RG           About GenesLikeMe

1 Novoseek inferred disease relationship for SLC2A4RG gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
huntington disease 49.8 4 18245850 (1), 14625278 (1)

Genetic Association Database (GAD): SLC2A4RG
Human Genome Epidemiology (HuGE) Navigator: SLC2A4RG (1 document)

Export disorders for SLC2A4RG gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for SLC2A4RG gene, integrated from 10 sources (see all 29):
(articles sorted by number of sources associating them with SLC2A4RG)
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  1. Identification of a 30-base pair regulatory element and novel DNA binding protein that regulates the human GLUT4 promoter in transgenic mice. (PubMed id 10825161)1, 2, 3 Oshel K.M.... Olson A.L. (J. Biol. Chem. 2000)
  2. Regulation of the human GLUT4 gene promoter: interaction between a transcriptional activator and myocyte enhancer factor 2A. (PubMed id 14630949)1, 2, 9 Knight J.B.... Olson A.L. (Proc. Natl. Acad. Sci. U.S.A. 2003)
  3. Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene. (PubMed id 14625278)1, 2, 9 Tanaka K.... Ikeda J.-E. (J. Biol. Chem. 2004)
  4. Polymorphism in postinsulin receptor signaling pathway is not associated with polycystic ovary syndrome. (PubMed id 18249389)1, 4, 9 Jones M.R....Stuckey B.G. (Fertil. Steril. 2008)
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  6. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
  7. GLUT4 enhancer factor (GEF) interacts with MEF2A and HDAC5 to regulate the GLUT4 promoter in adipocytes. (PubMed id 18216015)1, 9 Sparling D.P....Olson A.L. (J. Biol. Chem. 2008)
  8. Exercise increases MEF2- and GEF DNA-binding activity in human skeletal muscle. (PubMed id 16368714)1, 9 McGee S.L....Hargreaves M. (FASEB J. 2006)
  9. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (Nat. Genet. 2013)
  10. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. (PubMed id 23128233)1 Jostins L....Cho J.H. (Nature 2012)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 56731 HGNC: 15930 AceView: FLJ20406andSLC2A4RGandKIAA1847 Ensembl:ENSG00000125520 euGenes: HUgn56731
ECgene: SLC2A4RG H-InvDB: SLC2A4RG

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for SLC2A4RG Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for SLC2A4RG gene:
Search GeneIP for patents involving SLC2A4RG

GeneCards and IP:
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