Aliases for SLC2A4 Gene
External Ids for SLC2A4 Gene
Previous HGNC Symbols for SLC2A4 Gene
Previous GeneCards Identifiers for SLC2A4 Gene
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]
GeneCards Summary for SLC2A4 Gene
SLC2A4 (Solute Carrier Family 2 Member 4) is a Protein Coding gene. Diseases associated with SLC2A4 include Diabetes Mellitus, Noninsulin-Dependent and Metabolic Syndrome X. Among its related pathways are Glycosaminoglycan metabolism and Glucose / Energy Metabolism. GO annotations related to this gene include transmembrane transporter activity and glucose transmembrane transporter activity. An important paralog of this gene is ENSG00000251357.
UniProtKB/Swiss-Prot for SLC2A4 Gene
Insulin-regulated facilitative glucose transporter.