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SLC2A14 Gene

protein-coding   GIFtS: 51
GCID: GC12M007965

Solute Carrier Family 2 (Facilitated Glucose Transporter),...

(Previous names: solute carrier family 2 (facilitated glucose transporter),...)
(Previous symbol: SLC2A3P3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 2 (Facilitated Glucose Transporter), Member
141 2
     Glucose Transporter Type 142 3
GLUT142 3 5     Solute Carrier Family 2, Facilitated Glucose Transporter Member 142
SLC2A3P31 2     GLUT-143
Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3
Pseudogene 31 2
     GLUT33

External Ids:    HGNC: 183011   Entrez Gene: 1441952   Ensembl: ENSG000001732627   OMIM: 6110395   UniProtKB: Q8TDB83   

Export aliases for SLC2A14 gene to outside databases

Previous GC identifers: GC00U900937 GC12M007865 GC12M007857 GC12M007856


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC2A14 Gene:
Members of the glucose transporter (GLUT) family, including SLC2A14, are highly conserved integral membrane
proteins that transport hexoses such as glucose and fructose into all mammalian cells. GLUTs show tissue and
cell-type specific expression (Wu and Freeze, 2002 (PubMed 12504846)).(supplied by OMIM, Mar 2008)

GeneCards Summary for SLC2A14 Gene:
SLC2A14 (solute carrier family 2 (facilitated glucose transporter), member 14) is a protein-coding gene. Diseases associated with SLC2A14 include tonsillitis, and alzheimer's disease. GO annotations related to this gene include glucose transmembrane transporter activity. An important paralog of this gene is ENSG00000251357.

UniProtKB/Swiss-Prot: GTR14_HUMAN, Q8TDB8
Function: Facilitative glucose transporter (By similarity). May have a specific function related to
spermatogenesis

Gene Wiki entry for SLC2A14 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NT_009714.18  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC2A14 gene promoter:
         HOXA9B   HOXA9   FOXD3   E2F-2   AREB6   E2F   E2F-1   COMP1   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC2A14 promoter sequence
   Search Chromatin IP Primers for SLC2A14

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC2A14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.31   Ensembl cytogenetic band:  12p13.31   HGNC cytogenetic band: 12p13.31

SLC2A14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC2A14 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M007965:  view genomic region     (about GC identifiers)

Start:
7,965,108 bp from pter      End:
8,043,744 bp from pter
Size:
78,637 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: GTR14_HUMAN, Q8TDB8 (See protein sequence)
Recommended Name: Solute carrier family 2, facilitated glucose transporter member 14  
Size: 520 amino acids; 56320 Da
Miscellaneous: GLUT14 is a recent (less than 5 M year old) duplication of GLUT3
Secondary accessions: B3KVB5 B3KWW7 Q6UY84 Q8TDB9
Alternative splicing: 3 isoforms:  Q8TDB8-1   Q8TDB8-2   Q8TDB8-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC2A14: NX_Q8TDB8

Explore proteomics data for SLC2A14 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn67
  • Modification sites at PhosphoSitePlus

  • See SLC2A14 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001273162.1  NP_001273163.1  NP_001273164.1  NP_001273165.1  NP_001273166.1  NP_703150.1  

    ENSEMBL proteins: 
     ENSP00000340450   ENSP00000440480   ENSP00000407287   ENSP00000438484   ENSP00000379834  
     ENSP00000440492   ENSP00000445929   ENSP00000440043   ENSP00000438312   ENSP00000443217  
     ENSP00000440044   ENSP00000437653   ENSP00000442402   ENSP00000440980   ENSP00000443076  
     ENSP00000438876   ENSP00000444692   ENSP00000443903  

    SLC2A14 Human Recombinant Protein Products:

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    SLC2A14 Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Glucose transporter 14
    Class I transporters

    Selected InterPro protein domains (see all 6):
     IPR005829 Sugar_transporter_CS
     IPR005828 Sub_transporter
     IPR003663 Sugar/inositol_transpt
     IPR020846 MFS_dom
     IPR002945 Glc_transpt_3

    Graphical View of Domain Structure for InterPro Entry Q8TDB8

    ProtoNet protein and cluster: Q8TDB8

    4 Blocks protein domains:
    IPB000803 Mammalian facilitated glucose transporter family signature
    IPB002945 Glucose transporter type 3 (GLUT3) signature
    IPB003663 Sugar transporter signature
    IPB005829 Sugar transporter superfamily


    UniProtKB/Swiss-Prot: GTR14_HUMAN, Q8TDB8
    Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose
    transporter subfamily


    SLC2A14 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GTR14_HUMAN, Q8TDB8
    Function: Facilitative glucose transporter (By similarity). May have a specific function related to
    spermatogenesis

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005355glucose transmembrane transporter activity IEA--
    GO:0022857transmembrane transporter activity ----
    GO:0022891substrate-specific transmembrane transporter activity ----
         
    SLC2A14 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for SLC2A14:
     Increased S DNA content  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC2A14
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC2A14
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC2A14

    miRNA
    Products:
        
    miRTarBase miRNAs that target SLC2A14:
    hsa-mir-98-5p (MIRT027782), hsa-mir-335-5p (MIRT019157), hsa-mir-34a-5p (MIRT025478)

    Block miRNA regulation of human, mouse, rat SLC2A14 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLC2A14 (see all 11):
    hsa-miR-577 hsa-miR-3173-3p hsa-miR-15a hsa-miR-503 hsa-miR-497 hsa-miR-646 hsa-miR-424 hsa-miR-195
    SwitchGear 3'UTR luciferase reporter plasmidSLC2A14 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SLC2A14
    Predesigned siRNA for gene silencing in human, mouse, rat SLC2A14

    Gene Editing
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC2A14

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC2A14


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GTR14_HUMAN, Q8TDB8: Membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    cytosol1
    endoplasmic reticulum1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    SLC2A14 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SLC2A14 About    
    See pathways by source

    SuperPathContained pathways About
    1PAK Pathway
    Antioxidant Action of Vitamin-C0.56

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for SLC2A14
        Antioxidant Action of Vitamin-C


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC2A14
    Interactions:

        Search GeneGlobe Interaction Network for SLC2A14

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    Selected Interacting proteins for SLC2A14 (Q8TDB83 ENSP000003404504) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GOLGB1Q147893I2D: score=1 
    KDM6AENSP000003672034STRING: ENSP00000367203
    UTYENSP000003289394STRING: ENSP00000328939
    SLC1A3ENSP000002651134STRING: ENSP00000265113
    PAXIP1ENSP000003840484STRING: ENSP00000384048
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0007275multicellular organismal development IEA--
    GO:0007283spermatogenesis IEA--
    GO:0030154cell differentiation IEA--
    GO:0055085transmembrane transport ----

    SLC2A14 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC2A14 (GTR14)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SLC2A14 gene (6 alternative transcripts): 
    NM_001286233.1  NM_001286234.1  NM_001286235.1  NM_001286236.1  NM_001286237.1  NM_153449.3  

    Unigene Cluster for SLC2A14:

    Solute carrier family 2 (facilitated glucose transporter), member 14
    Hs.655169  [show with all ESTs]
    Unigene Representative Sequence: AK126026
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000340749(uc001qtl.3) ENST00000543909(uc001qtk.3) ENST00000431042(uc001qtm.3 uc010sgg.2)
    ENST00000542505(uc001qto.3) ENST00000396589(uc001qtn.3 uc010sgh.2)
    ENST00000535295 ENST00000539924 ENST00000546234 ENST00000542782 ENST00000535344
    ENST00000537557 ENST00000535266 ENST00000539738 ENST00000542916 ENST00000536594
    ENST00000535383 ENST00000535587 ENST00000539234
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SLC2A14 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLC2A14 (see all 11):
    hsa-miR-577 hsa-miR-3173-3p hsa-miR-15a hsa-miR-503 hsa-miR-497 hsa-miR-646 hsa-miR-424 hsa-miR-195
    SwitchGear 3'UTR luciferase reporter plasmidSLC2A14 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SLC2A14
    Predesigned siRNA for gene silencing in human, mouse, rat SLC2A14
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    GenScript: all cDNA clones in your preferred vector: SLC2A14 (NM_153449)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC2A14
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC2A14
    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat SLC2A14
      QuantiFast Probe-based Assays in human, mouse, rat SLC2A14

    Additional mRNA sequence: 

    AF481878.1 AF481879.1 AK122783.1 AK126026.1 AK299037.1 AK302881.1 AK316238.1 AL110298.1 
    AL832448.1 AY357941.1 BC060766.1 

    Selected DOTS entries (see all 27):

    DT.92012780  DT.40274075  DT.95069479  DT.91650532  DT.101981613  DT.121143764  DT.121143656  DT.92449965 
    DT.100860782  DT.121143757  DT.121143642  DT.99984415  DT.100697253  DT.121143635  DT.121143646  DT.121143718 
    DT.121143633  DT.121143694  DT.121143706  DT.121143717  DT.40114333  DT.40313028  DT.100696909  DT.100860785 

    Selected AceView cDNA sequences (see all 489):

    CD656442 AI206917 AA181772 BM561608 BM807032 AU185976 BM556081 BM553863 
    BM475101 AF481879 BM926950 BU175321 BX357715 BM556019 N57046 AA381487 
    BE550486 BM907815 AL702725 BQ441087 BM562542 BM927919 CD644645 BM476335 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC2A14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SLC2A14 Expression
    About this image


    SLC2A14 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Testis (Reproductive System)
    SLC2A14 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC2A14 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655169

    UniProtKB/Swiss-Prot: GTR14_HUMAN, Q8TDB8
    Tissue specificity: Expressed mainly in testis

        Custom PCR Arrays for SLC2A14
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC2A14

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC2A14 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves SLC2A36
    Gallus gallus solute carrier family 2 (facilitated...
    71(a)
    1 → many
    1(75323723-75331877)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    65(a)
    1 → many
    GL343236.1(1391723-1422178)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003308971 solute carrier family 2, facilitated glucose transporter more 60.01(n)
    60.69(a)
      100330897  XM_002667123.2  XP_002667169.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Glut16
    Glucose transporter 1
    29(a)
    1 → many
    3L(914074-993687)
    worm
    (Caenorhabditis elegans)
    Secernentea fgt-16
    R09B5.116
    (see all 15)
    Protein R09B5.11 (R09B5.11) mRNA, complete cds
    (see all 15)
    38(a)
    35(a)
    (see all 15)
    many ↔ many
    many ↔ many
    (see all 15)
    II(1504566-1509830) WBGene00019207
    V(1439205-1441871) WBGene00019979
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes HXT13(YEL069C)4 Hexose transporter, induced in the presence of non-fermentable more   --   5(23231-21537) 856640  NP_010845.1 
            Species with no ortholog for SLC2A14

    ENSEMBL Gene Tree for SLC2A14 (if available)
    TreeFam Gene Tree for SLC2A14 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC2A14 gene
    ENSG000002513572  SLC2A52  SLC2A72  SLC2A32  SLC2A92  SLC2A22  SLC2A42  SLC2A12  
    SLC2A112  
    12 SIMAP similar genes for SLC2A14 using alignment to 13 protein entries:     GTR14_HUMAN (see all proteins):
    SLC2A3    SLC2A2    SLC2A1    SLC2A4    SLC2A5    SLC2A9
    SLC2A11    SLC2A7    SLC2A11-a    SLC2A11-c    SLC2A10    SLC2A13

    SLC2A14 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC2A14 (see all 1557)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1901621931,2
    --7965937(+) AAAAGC/TAATGA 1 -- ds50010--------
    rs1447448791,2
    C--7966182(+) ATCAA-/AGAGTTT 1 -- ds50010--------
    rs18948241,2
    C,F,A,H--7966189(-) AGATGG/AAAACT 1 -- ds5001 ese329Minor allele frequency- A:0.34NS EA NA WA CSA 2549
    rs1828414111,2
    --7966199(+) TGAAGA/GACAGA 1 -- ds50010--------
    rs1440569511,2
    --7966225(+) ATGTAC/TAGACC 1 -- ds50010--------
    rs1852813371,2
    C--7966322(+) TTTTAC/TTCTAT 1 -- ds50010--------
    rs18948221,2
    C,F,A,H--7966373(-) AATAAA/CAACAG 1 -- ds50018Minor allele frequency- C:0.28EA NS WA NA CSA 281
    rs1910704041,2
    --7966414(+) ATTTAC/TGTAAT 1 -- ut310--------
    rs18948211,2
    C,A--7966505(-) GAGGGG/TGTTTA 1 -- ut311Minor allele frequency- T:0.50NA 2
    rs48834441,2
    C,A--7966511(+) CCCTCC/TGGCTT 1 -- ut31 ese32Minor allele frequency- T:0.25NA 4

    HapMap Linkage Disequilibrium report for SLC2A14 (7965108 - 8043744 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SLC2A14 (see all 57):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv186e201CNV Deletion23290073
    dgv185e201CNV Deletion23290073
    esv2671590CNV Deletion23128226
    esv2658754CNV Deletion23128226
    esv2745493CNV Deletion23290073
    esv2656717CNV Deletion23128226
    esv2745494CNV Deletion23290073
    dgv6e196CNV Duplication17116639
    dgv5e196CNV Duplication17116639
    esv2422393CNV Duplication17116639

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611039    OMIM disorders: --

    4 diseases for SLC2A14:    
    About MalaCards
    tonsillitis    alzheimer's disease    breast cancer    cerebritis


    SLC2A14 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC2A14

    Export disorders for SLC2A14 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC2A14 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with SLC2A14)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. GLUT14, a duplicon of GLUT3, is specifically expressed in testis as alternative splice forms. (PubMed id 12504846)1, 2, 3 Wu X. and Freeze H.H. (Genomics 2002)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    4. Genetic association of SLC2A14 polymorphism with Alzheimer's disease in a Han Chinese population. (PubMed id 22421804)1 Wang W....Tan L. (J. Mol. Neurosci. 2012)
    5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    6. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 144195 HGNC: 18301 AceView: SLC2A3andSLC2A14 Ensembl:ENSG00000173262 euGenes: HUgn144195
    ECgene: SLC2A14 H-InvDB: SLC2A14

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SLC2A14 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for SLC2A14 gene:
    Search GeneIP for patents involving SLC2A14

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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