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Aliases for SLC2A13 Gene

Aliases for SLC2A13 Gene

  • Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 13 2 3
  • H(+)-Myo-Inositol Symporter 2 3 4
  • HMIT 3 4 6
  • Solute Carrier Family 2 Member 13 3 4
  • H(+)-Myo-Inositol Cotransporter 3 4
  • Proton (H+) Myo-Inositol Symporter 3
  • Proton Myo-Inositol Cotransporter 3

External Ids for SLC2A13 Gene

Summaries for SLC2A13 Gene

GeneCards Summary for SLC2A13 Gene

SLC2A13 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 13) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include substrate-specific transmembrane transporter activity. An important paralog of this gene is SLC2A10.

UniProtKB/Swiss-Prot for SLC2A13 Gene

  • H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.

Gene Wiki entry for SLC2A13 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC2A13 Gene

Genomics for SLC2A13 Gene

Genomic Location for SLC2A13 Gene

39,755,021 bp from pter
40,106,089 bp from pter
351,069 bases
Minus strand

Genomic View for SLC2A13 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC2A13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC2A13 Gene

Regulatory Elements for SLC2A13 Gene

Proteins for SLC2A13 Gene

  • Protein details for SLC2A13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Proton myo-inositol cotransporter
    Protein Accession:
    Secondary Accessions:
    • Q17S07

    Protein attributes for SLC2A13 Gene

    648 amino acids
    Molecular mass:
    70371 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAI17118.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI17120.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAC51116.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for SLC2A13 Gene

Proteomics data for SLC2A13 Gene at MOPED

Post-translational modifications for SLC2A13 Gene

Other Protein References for SLC2A13 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC2A13 Gene

Domains for SLC2A13 Gene

Gene Families for SLC2A13 Gene


  • Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.:
    • Q96QE2
genes like me logo Genes that share domains with SLC2A13: view

Function for SLC2A13 Gene

Molecular function for SLC2A13 Gene

UniProtKB/Swiss-Prot Function: H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.

Gene Ontology (GO) - Molecular Function for SLC2A13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004872 receptor activity --
GO:0005351 sugar:proton symporter activity IBA --
GO:0005355 glucose transmembrane transporter activity IBA --
GO:0022857 transmembrane transporter activity --
GO:0022891 substrate-specific transmembrane transporter activity --
genes like me logo Genes that share ontologies with SLC2A13: view

Phenotypes for SLC2A13 Gene

GenomeRNAi human phenotypes for SLC2A13:
genes like me logo Genes that share phenotypes with SLC2A13: view

miRNA for SLC2A13 Gene

miRTarBase miRNAs that target SLC2A13

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SLC2A13 Gene

Localization for SLC2A13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC2A13 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SLC2A13 Gene COMPARTMENTS Subcellular localization image for SLC2A13 gene
Compartment Confidence
plasma membrane 4
peroxisome 2

Gene Ontology (GO) - Cellular Components for SLC2A13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016020 membrane --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with SLC2A13: view

Pathways for SLC2A13 Gene

genes like me logo Genes that share pathways with SLC2A13: view

Interacting Proteins for SLC2A13 Gene

Gene Ontology (GO) - Biological Process for SLC2A13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007275 multicellular organismal development --
GO:0015992 proton transport IBA --
GO:0035428 hexose transmembrane transport IBA --
GO:0046323 glucose import IBA --
GO:0055085 transmembrane transport TAS --
genes like me logo Genes that share ontologies with SLC2A13: view

Transcripts for SLC2A13 Gene

Unigene Clusters for SLC2A13 Gene

Solute carrier family 2 (facilitated glucose transporter), member 13:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC2A13 Gene

No ASD Table

Relevant External Links for SLC2A13 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC2A13 Gene

mRNA expression in normal human tissues for SLC2A13 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC2A13 Gene

This gene is overexpressed in Brain - Anterior cingulate cortex (BA24) (4.5) and Brain - Frontal Cortex (BA9) (4.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SLC2A13 Gene

SOURCE GeneReport for Unigene cluster for SLC2A13 Gene Hs.558595

mRNA Expression by UniProt/SwissProt for SLC2A13 Gene

Tissue specificity: Predominantly expressed in the brain.
genes like me logo Genes that share expressions with SLC2A13: view

Orthologs for SLC2A13 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SLC2A13 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SLC2A13 36
  • 99.69 (n)
  • 99.54 (a)
SLC2A13 37
  • 100 (a)
(Bos Taurus)
Mammalia SLC2A13 36
  • 94.7 (n)
  • 97.07 (a)
SLC2A13 37
  • 97 (a)
(Canis familiaris)
Mammalia SLC2A13 36
  • 93.93 (n)
  • 96.3 (a)
SLC2A13 37
  • 96 (a)
(Mus musculus)
Mammalia Slc2a13 36
  • 85.4 (n)
  • 89.95 (a)
Slc2a13 16
Slc2a13 37
  • 88 (a)
(Monodelphis domestica)
Mammalia SLC2A13 37
  • 86 (a)
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 85 (a)
-- 37
  • 92 (a)
(Rattus norvegicus)
Mammalia Slc2a13 36
  • 85.35 (n)
  • 91.05 (a)
(Gallus gallus)
Aves SLC2A13 36
  • 81.7 (n)
  • 86.31 (a)
SLC2A13 37
  • 82 (a)
(Anolis carolinensis)
Reptilia SLC2A13 37
  • 86 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia slc2a13 36
  • 76.07 (n)
  • 82.79 (a)
(Danio rerio)
Actinopterygii SLC2A13 (1 of 3) 37
  • 65 (a)
SLC2A13 (3 of 3) 37
  • 72 (a)
slc2a13b 36
  • 65.03 (n)
  • 69 (a)
slc2a13b 37
  • 66 (a)
(Caenorhabditis elegans)
Secernentea hmit-1.1 37
  • 37 (a)
hmit-1.2 37
  • 35 (a)
hmit-1.3 36
  • 50.4 (n)
  • 44.61 (a)
hmit-1.3 37
  • 39 (a)
Y51A2D.5 38
  • 37 (a)
M01F1.5 38
  • 39 (a)
Y51A2D.4 38
  • 39 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFR343C 36
  • 46.18 (n)
  • 34.63 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 37
  • 27 (a)
ITR1 37
  • 24 (a)
ITR2 36
  • 47.88 (n)
  • 35.33 (a)
ITR2 37
  • 25 (a)
ITR2 39
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C12309g 36
  • 48.03 (n)
  • 35 (a)
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.1070 36
thale cress
(Arabidopsis thaliana)
eudicotyledons INT1 36
  • 51.42 (n)
  • 42.77 (a)
(Oryza sativa)
Liliopsida Os.10117 36
Os04g0491700 36
  • 50.08 (n)
  • 44.14 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes itr2 36
  • 48.63 (n)
  • 36.81 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 46 (a)
Species with no ortholog for SLC2A13:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC2A13 Gene

Gene Tree for SLC2A13 (if available)
Gene Tree for SLC2A13 (if available)

Paralogs for SLC2A13 Gene

Paralogs for SLC2A13 Gene

Selected SIMAP similar genes for SLC2A13 Gene using alignment to 3 proteins: Pseudogenes for SLC2A13 Gene

genes like me logo Genes that share paralogs with SLC2A13: view

Variants for SLC2A13 Gene

Sequence variations from dbSNP and Humsavar for SLC2A13 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs476592 -- 39,998,988(+) acccc(A/G)aatgg intron-variant
rs478527 -- 40,024,880(+) GGCGC(A/G)GCAAC intron-variant
rs481241 -- 39,973,326(+) TTTCT(C/T)TTGGT intron-variant
rs483163 -- 40,031,151(+) AGGAA(C/T)GGATG intron-variant
rs489044 -- 40,020,694(+) AAAAA(A/G)GGGTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC2A13 Gene

Variant ID Type Subtype PubMed ID
nsv899024 CNV Loss 21882294
nsv428280 CNV Loss 18775914
esv2677205 CNV Deletion 23128226
nsv899025 CNV Loss 21882294
esv2745779 CNV Deletion 23290073
esv2678856 CNV Deletion 23128226
nsv899026 CNV Loss 21882294
nsv522471 CNV Loss 19592680
esv2745780 CNV Deletion 23290073
esv2745781 CNV Deletion 23290073
dgv506e1 CNV Complex 17122850
nsv8966 CNV Loss 18304495
nsv436152 CNV Deletion 17901297
esv2421863 CNV Deletion 20811451
esv22092 CNV Loss 19812545
esv2657004 CNV Deletion 23128226
nsv515811 CNV Loss 19592680
nsv442269 CNV CNV 18776908
nsv514669 CNV Loss 21397061
nsv8967 CNV Gain 18304495
nsv681 CNV Insertion 18451855
nsv899027 CNV Loss 21882294
nsv819704 CNV Loss 19587683
esv2661429 CNV Deletion 23128226
dgv1415n71 CNV Loss 21882294
esv27366 CNV Loss 19812545

Relevant External Links for SLC2A13 Gene

HapMap Linkage Disequilibrium report

Disorders for SLC2A13 Gene

Relevant External Links for SLC2A13

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with SLC2A13: view

No data available for UniProtKB/Swiss-Prot for SLC2A13 Gene

Publications for SLC2A13 Gene

  1. Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain. (PMID: 11500374) Uldry M. … Thorens B. (EMBO J. 2001) 2 3 4
  2. Evaluation of expression and function of the H+/myo-inositol transporter HMIT. (PMID: 19607714) Di Daniel E. … Maycox P.R. (BMC Cell Biol. 2009) 3 23
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  5. Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. (PMID: 19915576) Satake W. … Toda T. (Nat. Genet. 2009) 3 49

Products for SLC2A13 Gene

  • antibodies-online peptides for SLC2A13
  • antibodies-online antibodies for SLC2A13
  • antibodies-online kits for SLC2A13

Sources for SLC2A13 Gene

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