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SLC2A12 Gene

protein-coding   GIFtS: 54
GCID: GC06M134349

Solute Carrier Family 2 (Facilitated Glucose Transporter),...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 2 (Facilitated Glucose Transporter), Member
121 2
GLUT122 3 5
Glucose Transporter Type 122 3
GLUT-122 3
GLUT82 3
Solute Carrier Family 2, Facilitated Glucose Transporter Member 122

External Ids:    HGNC: 180671   Entrez Gene: 1540912   Ensembl: ENSG000001464117   OMIM: 6103725   UniProtKB: Q8TD203   

Export aliases for SLC2A12 gene to outside databases

Previous GC identifers: GC06M133933 GC06M134155 GC06M134288 GC06M134292 GC06M131877


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC2A12 Gene:
SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion
(Rogers et al., 2002). This family of transporters show conservation of 12 transmembrane helices as well as
functionally significant amino acid residues (Joost and Thorens, 2001 (PubMed 11780753)).(supplied by OMIM, Mar
2008)

GeneCards Summary for SLC2A12 Gene:
SLC2A12 (solute carrier family 2 (facilitated glucose transporter), member 12) is a protein-coding gene. GO annotations related to this gene include substrate-specific transmembrane transporter activity. An important paralog of this gene is SLC2A10.

UniProtKB/Swiss-Prot: GTR12_HUMAN, Q8TD20
Function: Facilitative glucose transporter (By similarity)

Gene Wiki entry for SLC2A12 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC2A12 gene promoter:
         c-Fos   AP-1   JunB   STAT1beta   Fra-1   FosB   E47   JunD   Hand1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC2A12 promoter sequence
   Search Chromatin IP Primers for SLC2A12

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC2A12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q23.2   Ensembl cytogenetic band:  6q23.2   HGNC cytogenetic band: 6q23.2

SLC2A12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC2A12 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M134349:  view genomic region     (about GC identifiers)

Start:
134,308,719 bp from pter      End:
134,373,789 bp from pter
Size:
65,071 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: GTR12_HUMAN, Q8TD20 (See protein sequence)
Recommended Name: Solute carrier family 2, facilitated glucose transporter member 12  
Size: 617 amino acids; 66966 Da
Sequence caution: Sequence=BAB71214.1; Type=Erroneous initiation;
Secondary accessions: B3KV17 Q7Z6U3 Q96MR8

Explore the universe of human proteins at neXtProt for SLC2A12: NX_Q8TD20

Explore proteomics data for SLC2A12 at MOPED

Post-translational modifications: 

  • N-glycosylated (By similarity)1
  • Ubiquitination2 at Lys254
  • Glycosylation2 at Asn371, Asn383, Asn396, Asn401, Thr432, Thr433, Ser434, Thr445
  • Modification sites at PhosphoSitePlus

  • See SLC2A12 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_660159.1  
    ENSEMBL proteins: 
     ENSP00000275230  
    Reactome Protein details: Q8TD20

    SLC2A12 Human Recombinant Protein Products:

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    Browse Proteins at Cloud-Clone Corp.

     
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    antibodies-online proteins for SLC2A12 

     
    antibodies-online peptides for SLC2A12

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    antibodies-online antibodies for SLC2A12 (33 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Glucose transporter 12
    Class II transporters

    5 InterPro protein domains:
     IPR005829 Sugar_transporter_CS
     IPR005828 Sub_transporter
     IPR003663 Sugar/inositol_transpt
     IPR020846 MFS_dom
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q8TD20

    ProtoNet protein and cluster: Q8TD20

    2 Blocks protein domains:
    IPB003663 Sugar transporter signature
    IPB005829 Sugar transporter superfamily


    UniProtKB/Swiss-Prot: GTR12_HUMAN, Q8TD20
    Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose
    transporter subfamily


    Find genes that share domains with SLC2A12           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GTR12_HUMAN, Q8TD20
    Function: Facilitative glucose transporter (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0022857transmembrane transporter activity ----
    GO:0022891substrate-specific transmembrane transporter activity IEA--
         
    Find genes that share ontologies with SLC2A12           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC2A12:
     Decreased POU5F1-GFP protein e 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC2A12
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    miRNA
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    miRTarBase miRNAs that target SLC2A12:
    hsa-mir-335-5p (MIRT017063)

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    Selected qRT-PCR Assays for microRNAs that regulate SLC2A12 (see all 48):
    hsa-miR-4307 hsa-miR-3607-3p hsa-let-7d hsa-miR-3616-5p hsa-miR-488 hsa-miR-578 hsa-let-7g hsa-miR-149
    SwitchGear 3'UTR luciferase reporter plasmidSLC2A12 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GTR12_HUMAN, Q8TD20: Endomembrane system; Multi-pass membrane protein (By similarity). Cytoplasm, perinuclear
    region. Note=Localizes primarily perinuclear region in the absence of insulin
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane4
    endosome1
    peroxisome1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0012505endomembrane system IEA--
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--
    GO:0048471perinuclear region of cytoplasm IEA--

    Find genes that share ontologies with SLC2A12           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SLC2A12 About    
    See pathways by source

    SuperPathContained pathways About
    1Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    SLC-mediated transmembrane transport0.47
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    Transmembrane transport of small molecules0.47
    Facilitative Na+-independent glucose transporters0.00
    2PAK Pathway
    Antioxidant Action of Vitamin-C0.56
    3HIF1Alpha Pathway
    HIF1Alpha Pathway


    Find genes that share SuperPaths with SLC2A12           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for SLC2A12
        Antioxidant Action of Vitamin-C
    HIF1Alpha Pathway


    1 Reactome Pathway for SLC2A12
        Facilitative Na+-independent glucose transporters


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC2A12
    Interactions:

        Search GeneGlobe Interaction Network for SLC2A12

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for SLC2A12 (ENSP000002752304) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GALTENSP000003681194STRING: ENSP00000368119
    GALMENSP000002722524STRING: ENSP00000272252
    DHDHENSP000002214034STRING: ENSP00000221403
    --ENSP000003130264STRING: ENSP00000313026
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015758glucose transport IEA--
    GO:0055085transmembrane transport TAS--

    Find genes that share ontologies with SLC2A12           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC2A12 (GTR12)

    1 Novoseek inferred chemical compound relationship for SLC2A12 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glucose 48 16 11832379 (3), 12899849 (3), 16091581 (3), 16775550 (2) (see all 8)



    Find genes that share compounds with SLC2A12           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SLC2A12 gene: 
    NM_145176.2  

    Unigene Cluster for SLC2A12:

    Solute carrier family 2 (facilitated glucose transporter), member 12
    Hs.486508  [show with all ESTs]
    Unigene Representative Sequence: AL833602
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000275230(uc003qem.1)
    miRNA
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    hsa-miR-4307 hsa-miR-3607-3p hsa-let-7d hsa-miR-3616-5p hsa-miR-488 hsa-miR-578 hsa-let-7g hsa-miR-149
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      QuantiTect SYBR Green Assays in human, mouse, rat SLC2A12
      QuantiFast Probe-based Assays in human, mouse, rat SLC2A12

    Additional mRNA sequence: 

    AK054852.1 AK056554.1 AK122628.1 AK226098.1 AL833602.1 AY046419.1 BC070149.1 BX648889.1 

    5 DOTS entries:

    DT.100641620  DT.95222494  DT.92027297  DT.121391998  DT.448696 

    Selected AceView cDNA sequences (see all 68):

    BC070149 CA397314 AI281015 BX279711 AI347360 NM_145176 BM839199 AY046419 
    BF085782 CB122044 CA314145 AK056554 CD103684 BP379203 BX472325 AI033891 
    H87580 N30540 BU101998 BX648889 AA706221 AK054852 CD512309 AA449435 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC2A12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SLC2A12 Expression
    About this image


    SLC2A12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 7 entries
             Mature Choroid Plexus Cells Choroid Plexus
             Cerebral Cortex
     
     Epithelial Cells
             Mature Choroid Plexus Cells Choroid Plexus
     
     Neural Tube (Nervous System)    fully expand to see all 4 entries
             Metencephalon
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 3 entries
             Villous Cytotrophoblast Cells Chorionic Villus
     
     Epiblast (Early Embryonic Tissues)
             Epiblast Stem Cell line 7
    SLC2A12 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC2A12 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.486508

    UniProtKB/Swiss-Prot: GTR12_HUMAN, Q8TD20
    Tissue specificity: Predominantly expressed in skeletal muscle, heart and prostate, with lower levels in brain,
    placenta and kidney

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC2A12 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc2a121 , 5 solute carrier family 2 (facilitated glucose transporter), more1, 5 82.87(n)1
    84.28(a)1
      10 (10.21 cM)5
    3531691  NM_178934.41  NP_849265.21 
     226450115 
    chicken
    (Gallus gallus)
    Aves SLC2A121 solute carrier family 2 (facilitated glucose transporter), more 71.47(n)
    73.93(a)
      421696  XM_419733.3  XP_419733.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC2A126
    solute carrier family 2 (facilitated glucose trans...
    62(a)
    1 ↔ 1
    GL343200.1(3718296-3758862)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia slc2a121 solute carrier family 2 (facilitated glucose transporter), more 64.38(n)
    63.6(a)
      100487147  XM_002935807.2  XP_002935853.2 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc660272 hypothetical protein MGC66027 70.4(n)   393510  BC056306.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ITR16
    ITR26
    (see all 3)
    Myo-inositol transporter with strong similarity to...
    Myo-inositol transporter with strong similarity to...
    (see all 3)
    22(a)
    22(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    IV(1443713-1445467) YDR497C
    XV(124001-125830) YOL103W
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G170101 AT5G17010 49.11(n)
    37.44(a)
      831564  NM_180505.2  NP_850836.2 
    rice
    (Oryza sativa)
    Liliopsida Os10g05792001 Os10g0579200 47.15(n)
    38.55(a)
      4349512  NM_001072037.1  NP_001065505.1 


    ENSEMBL Gene Tree for SLC2A12 (if available)
    TreeFam Gene Tree for SLC2A12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC2A12 gene
    SLC2A102  SLC2A132  
    2 SIMAP similar genes for SLC2A12 using alignment to 1 protein entry:     GTR12_HUMAN:
    SLC2A10    SLC2A13

    Find genes that share paralogs with SLC2A12           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC2A12 (see all 1414)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1822431751,2
    Cuntested1134350310(+) TTGGAA/GGAAGA 2 P L mis10--------
    rs717866861,2
    C--131925198(+) CTGAC-/AAAAA/
    AAAAAAAAA
    AAAAA
    1 -- int10--------
    rs1180040111,2
    C,F--134309312(+) TTCCCC/TTTGCT 1 -- ut311Minor allele frequency- T:0.01EA 120
    rs611417201,2
    --134309313(+) TCCCCG/TTGCTG 1 -- ut310--------
    rs1501835821,2
    C--134309321(+) CTGTAA/TCTTAT 1 -- ut310--------
    rs94836391,2
    C,F--134309364(+) TGAGAT/CTGCTA 1 -- ut314Minor allele frequency- C:0.17WA CSA NA 242
    rs1851877481,2
    --134309494(+) TAGTGC/TAACCA 1 -- ut310--------
    rs1158139331,2
    C,F--134309513(+) TATACC/TTAGAA 1 -- ut313Minor allele frequency- T:0.03WA NA EA 358
    rs771471941,2
    F--134309531(+) TGAGTG/AGAGAG 1 -- ut311Minor allele frequency- A:0.01WA 118
    rs1457640781,2
    --134309546(+) ATTAGC/TTTCTC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SLC2A12 (134308719 - 134373789 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for SLC2A12:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2659392CNV Deletion23128226
    esv2732731CNV Deletion23290073
    esv2732730CNV Deletion23290073
    esv2671195CNV Deletion23128226
    esv34122CNV Loss18971310

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC2A12
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC2A12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610372    OMIM disorders: --


    Find genes that share disorders with SLC2A12           About GenesLikeMe

    3 Novoseek inferred disease relationships for SLC2A12 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    breast cancer 13.8 3 12706881 (2), 11832379 (1)
    tumors 0 6 16892013 (3), 15705862 (2)
    cancer 0 1 16892013 (1)

    Genetic Association Database (GAD): SLC2A12
    Human Genome Epidemiology (HuGE) Navigator: SLC2A12 (3 documents)

    Export disorders for SLC2A12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC2A12 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with SLC2A12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel glucose transporter-like protein -- GLUT- 12. (PubMed id 11832379)1, 2, 3, 9 Rogers S.... Best J.D. (Am. J. Physiol. 2002)
    2. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)1, 4 He C....Hunter D.J. (Hum. Genet. 2010)
    3. Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. (PubMed id 18978678)1, 4 Vieira A.R....Marazita M.L. (Genet. Med. 2008)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review). (PubMed id 11780753)1, 3 Joost H.G. and Thorens B. (Mol. Membr. Biol. 2001)
    6. Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy. (PubMed id 16091581)1, 9 Linden K.C....Rogers S. (Am. J. Physiol. Renal Physiol. 2006)
    7. Hexose transporter mRNAs for GLUT4, GLUT5, and GLUT12 predominate in human muscle. (PubMed id 16803853)1, 9 Stuart C.A....Ferrando A.A. (Am. J. Physiol. Endocrinol. Metab. 2006)
    8. Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8. (PubMed id 23396969)1 Corpe C.P....Levine M. (J. Biol. Chem. 2013)
    9. Expression of conventional and novel glucose transporters, GLUT1, -9, -10, and -12, in vascular smooth muscle cells. (PubMed id 23302780)1 Pyla R....Segar L. (Am. J. Physiol., Cell Physiol. 2013)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 154091 HGNC: 18067 AceView: SLC2A12 Ensembl:ENSG00000146411 euGenes: HUgn154091
    ECgene: SLC2A12 H-InvDB: SLC2A12

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC2A12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for SLC2A12 gene:
    Search GeneIP for patents involving SLC2A12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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