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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC2A12 Gene

protein-coding   GIFtS: 51
GCID: GC06M134349

solute carrier family 2 (facilitated glucose transporter),...
 Explore 12 diseases affiliated with
SLC2A12 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC2A12    

Aliases
for SLC2A12 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 121 2
GLUT121 2 3
GLUT81 2 3
Glucose Transporter Type 122 3
GLUT-122 3
Solute Carrier Family 2, Facilitated Glucose Transporter Member 122

External Ids:    HGNC: 180671   Entrez Gene: 1540912   Ensembl: ENSG000001464117   OMIM: 6103725   UniProtKB: Q8TD203   

Export aliases for SLC2A12 gene to outside databases

Previous GC identifers: GC06M133933 GC06M134155 GC06M134288 GC06M134292 GC06M131877


Summaries
for SLC2A12 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SLC2A12:
SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Rogers et
al., 2002). This family of transporters show conservation of 12 transmembrane helices as well as functionally
significant amino acid residues (Joost and Thorens, 2001 (PubMed 11780753)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: GTR12_HUMAN, Q8TD20
Function: Facilitative glucose transporter (By similarity)

Gene Wiki entry for SLC2A12


Genomic Views
for SLC2A12 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_025741.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC2A12 gene promoter:
         c-Fos   AP-1   JunB   STAT1beta   Fra-1   FosB   E47   JunD   Hand1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC2A12 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC2A12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC2A12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q23.2   Ensembl cytogenetic band:  6q23.2   HGNC cytogenetic band: 6q23.2

SLC2A12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC2A12 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M134349:  view genomic region     (about GC identifiers)

Start:
 134,308,719 bp from pter      End:
 134,373,789 bp from pter
Size:
 65,071 bases      Orientation:
 minus strand

Proteins
for SLC2A12 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: GTR12_HUMAN, Q8TD20 (See protein sequence)
Recommended Name: Solute carrier family 2, facilitated glucose transporter member 12  
Size: 617 amino acids; 66966 Da
Subcellular location: Endomembrane system; Multi-pass membrane protein (By similarity). Cytoplasm, perinuclear region.
Note=Localizes primarily perinuclear region in the absence of insulin
Sequence caution: Sequence=BAB71214.1; Type=Erroneous initiation;
Secondary accessions: B3KV17 Q7Z6U3 Q96MR8

Explore the universe of human proteins at neXtProt for SLC2A12: NX_Q8TD20

Post-translational modifications:

  • N-glycosylated (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TD20

    • SLC2A12 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_660159.1  
    ENSEMBL proteins: 
     ENSP00000275230  
    Reactome Protein details: Q8TD20
    Human Recombinant Protein Products: 
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    Novus Biologicals SLC2A12 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SLC2A12

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0012505endomembrane system IEA--
    GO:0016021integral to membrane IEA--
    GO:0048471perinuclear region of cytoplasm IEA--


    SLC2A12 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SLC2A12

    Protein Domains /
    Families
    for SLC2A12 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC2A12 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR005829 Sugar_transporter_CS
     IPR005828 Sub_transporter
     IPR003663 Sugar/inositol_transpt
     IPR020846 MFS_dom
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q8TD20

    ProtoNet protein and cluster: Q8TD20

    2 Blocks protein families:
    IPB003663 Sugar transporter signature
    IPB005829 Sugar transporter superfamily


    UniProtKB/Swiss-Prot: GTR12_HUMAN, Q8TD20
    Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter
    subfamily


    Function
    for SLC2A12 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: GTR12_HUMAN, Q8TD20
    Function: Facilitative glucose transporter (By similarity)

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC2A12
    8/48 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC2A12 (see all 48):
    hsa-miR-4307 hsa-miR-3607-3p hsa-let-7d hsa-miR-3616-5p hsa-miR-488 hsa-miR-578 hsa-let-7g hsa-miR-149
    SwitchGear 3'UTR luciferase reporter plasmid: SLC2A12 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC2A12 (see all 7)
    OriGene shRNA RFP: SLC2A12
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    Gene Editing
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    Clone
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    Cell Line
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    In Situ Assay
    Products:       
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0022891substrate-specific transmembrane transporter activity IEA--


    SLC2A12 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SLC2A12:
     Decreased POU5F1-GFP protein e 


    Pathways & Interactions
    for SLC2A12 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1SLC-mediated transmembrane transport
    		SLC-mediated transmembrane transport1.00
    		Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    		Transmembrane transport of small molecules0.50
    2Facilitative Na+-independent glucose transporters
    		Facilitative Na+-independent glucose transporters1.00
    3HIF1Alpha Pathway
    		HIF1Alpha Pathway1.00
    4PAK Pathway
    		Antioxidant Action of Vitamin-C0.56

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for SLC2A12
        Antioxidant Action of Vitamin-C
    HIF1Alpha Pathway

    4        Reactome Pathways for SLC2A12
        SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Facilitative Na+-independent glucose transporters



    SLC2A12 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC2A12

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008643carbohydrate transport IEA--
    GO:0055085transmembrane transport TAS--


    SLC2A12 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC2A12 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC2A12 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC2A12
    1 Novoseek chemical compound relationship for SLC2A12 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glucose 48 16 11832379 (3), 12899849 (3), 16091581 (3), 16775550 (2) (see all 8)

    Search CenterWatch for drugs/clinical trials and news about SLC2A12 / GTR12 

    Transcripts
    for SLC2A12 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC2A12 gene: 
    NM_145176.2  

    Unigene Cluster for SLC2A12:

    Solute carrier family 2 (facilitated glucose transporter), member 12
    Hs.486508  [show with all ESTs]
    Unigene Representative Sequence: AL833602
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000275230(uc003qem.1)

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC2A12
    8/48 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC2A12 (see all 48):
    hsa-miR-4307 hsa-miR-3607-3p hsa-let-7d hsa-miR-3616-5p hsa-miR-488 hsa-miR-578 hsa-let-7g hsa-miR-149
    SwitchGear 3'UTR luciferase reporter plasmid: SLC2A12 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC2A12 (see all 7)
    OriGene shRNA RFP: SLC2A12
    OriGene siRNA: SLC2A12
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC2A12
    Clone
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SLC2A12 (NM_145176)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC2A12
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC2A12 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC2A12
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC2A12

    Additional cDNA sequence: 

    AK054852.1 AK056554.1 AK122628.1 AK226098.1 AL833602.1 AY046419.1 BC070149.1 BX648889.1 

    5 DOTS entries:

    DT.100641620  DT.95222494  DT.92027297  DT.121391998  DT.448696 

    24/68 AceView cDNA sequences (see all 68):

    BF085782 BC070149 NM_145176 BX279711 AI281015 BM839199 CA397314 AI347360 
    AY046419 CB051433 AK054852 N20817 BX648889 BF033803 BX472325 CB122044 
    BU101998 CD512309 H87580 CD103684 N30540 BE645506 N27704 AA706221 

    GeneLoc Exon Structure


    Expression
    for SLC2A12 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC2A12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SLC2A12 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    9 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainChoroid PlexusMature Choroid Plexus CellsChoroid Plexus
    PlacentaChorionic VillusSyncytiotrophoblast Multinuclear CellsExtraembryonic Tissues, Placenta
    PlacentaChorionic VillusVillous Cytotrophoblast CellsExtraembryonic Tissues, Placenta
    PlacentaExtravillous Cytotrophoblast LayerExtravillous Cytotrophoblast CellsExtraembryonic Tissues, Placenta
    Neural TubeNeural TubeSpinal Neural Tube CellsNeural Ectoderm
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    EyeRetinaEye
    Spinal CordPresumptive Spinal CordSpinal Cord
    Spinal CordSpinal Ventral ColumnsSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    PureStem™ progenitor EN13 (Embryonic Progenitor Cell)
    PureStem™ progenitor EN7 (Embryonic Progenitor Cell)
    Posterior foregut-like cells (A scalable, suspensi...)

    See SLC2A12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC2A12

    SOURCE GeneReport for Unigene cluster: Hs.486508

    UniProtKB/Swiss-Prot: GTR12_HUMAN, Q8TD20
    Tissue specificity: Predominantly expressed in skeletal muscle, heart and prostate, with lower levels in brain,
    placenta and kidney

        SABiosciences Custom PCR Arrays for SLC2A12
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    In Situ
    Assay Products:     
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    Orthologs
    for SLC2A12 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for SLC2A12 gene from 6/17 species (see all 17)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SLC2A121 solute carrier family 2 (facilitated glucose transporter), more 71.47(n)
    73.93(a)    		   421696  XM_419733.2  XP_419733.1 
    lizard
    (Anolis carolinensis)    		 Reptilia SLC2A126
    		 --
    		 71(a)
    		 1 ↔ 1
    		 GL343200.1(3745053-3758826)
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc660272 hypothetical protein MGC66027 70.4(n)   393510  BC056306.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT5G170101 D-xylose-proton symporter-like 2 49.31(n)
    37.71(a)    		   831564  NM_180504.3  NP_850835.2 
    rice
    (Oryza sativa)    		 Liliopsida Os10g05792001 hypothetical protein 47.09(n)
    38.35(a)    		   4349512  NM_001072037.1  NP_001065505.1 
    E. coli
    (Escherichia coli)    		 Gamma proteobacteria araE6
    galP6
    		 D-galactose transporter
    		 31(a)
    30(a)
    		 many ↔ many
    many ↔ many
    		 Chromosome(2978786-2980204)
    Chromosome(3086306-3087700)


    ENSEMBL Gene Tree for SLC2A12 (if available)
    TreeFam Gene Tree for SLC2A12 (if available) 

    Paralogs
    for SLC2A12 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC2A12 gene
    SLC2A102  SLC2A132  
    2 SIMAP similar genes for SLC2A12 using alignment to 1 protein entry:     GTR12_HUMAN:
    SLC2A10    SLC2A13

    SLC2A12 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC2A12 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1180 NCBI SNPs in SLC2A12 are shown (see all 1180)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1822431751,2
    		C,other134350310(+) TTGGAA/GGAAGA 2 P L mis10--------
    rs1180040111,2
    		--134309312(+) TTCCCC/TTTGCT 1 -- ut311Minor allele frequency- T:0.01EA 120
    rs611417201,2
    		--134309313(+) TCCCCG/TTGCTG 1 -- ut310--------
    rs1501835821,2
    		C,--134309321(+) CTGTAA/TCTTAT 1 -- ut310--------
    rs94836391,2
    		C,F,--134309364(+) TGAGAT/CTGCTA 1 -- ut314Minor allele frequency- C:0.17WA CSA NA 242
    rs1851877481,2
    		--134309494(+) TAGTGC/TAACCA 1 -- ut310--------
    rs1158139331,2
    		C,F,--134309513(+) TATACC/TTAGAA 1 -- ut313Minor allele frequency- T:0.03WA NA EA 358
    rs771471941,2
    		--134309531(+) TGAGTG/AGAGAG 1 -- ut311Minor allele frequency- A:0.01WA 118
    rs1457640781,2
    		--134309546(+) ATTAGC/TTTCTC 1 -- ut310--------
    rs763056991,2
    		C,--134309568(+) AATGGG/AGACAA 1 -- ut313Minor allele frequency- A:0.04CSA WA NA 240

    HapMap Linkage Disequilibrium report for SLC2A12 (134308719 - 134373789 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for SLC2A12
         1 CNV: 47958

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for SLC2A12 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC2A12 for disorders           About GeneDecksing

    OMIM gene information: 610372    OMIM disorders: --

    12 diseases for SLC2A12:    About MalaCards
    cleft lip/palate    cleft lip    endometrial adenocarcinoma    nephropathy
    breast cancer    adenocarcinoma    prostate cancer    hypertension
    prostatitis    tuberculosis    malaria    mycobacterium tuberculosis

    3 Novoseek disease relationships for SLC2A12 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    breast cancer 13.8 3 12706881 (2), 11832379 (1)
    tumors 0 6 16892013 (3), 15705862 (2)
    cancer 0 1 16892013 (1)

    Human Genome Epidemiology (HuGE) Navigator: SLC2A12 (3 documents)

    Export disorders for SLC2A12 gene to outside databases

    Publications
    for SLC2A12 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC2A12 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with SLC2A12)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel glucose transporter-like protein -- GLUT- 12. (PubMed id 11832379)1, 2, 3, 9 Rogers S.... Best J.D. (2002)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review). (PubMed id 11780753)1, 3 Joost H.G. and Thorens B. (2001)
    4. Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy. (PubMed id 16091581)1, 9 Linden K.C....Rogers S. (2006)
    5. Hexose transporter mRNAs for GLUT4, GLUT5, and GLUT12 predominate in human muscle. (PubMed id 16803853)1, 9 Stuart C.A....Ferrando A.A. (2006)
    6. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    7. Genetic variability of the fatty acid synthase pathwa y is not associated with prostate cancer risk in the European Prospective Inves tigation on Cancer (EPIC). (PubMed id 20965718)1 Campa D....Canzian F. (2010)
    8. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)1 He C....Hunter D.J. (2010)
    9. Insulin-stimulated translocation of glucose transport er (GLUT) 12 parallels that of GLUT4 in normal muscle. (PubMed id 19549745)1 Stuart C.A....Yin D. (2009)
    10. Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. (PubMed id 18978678)1 Vieira A.R....Marazita M.L. (2008)

    External Searches for SLC2A12 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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    Genome Databases showing SLC2A12 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 154091 HGNC: 18067 AceView: SLC2A12 Ensembl:ENSG00000146411 euGenes: HUgn154091
    ECgene: SLC2A12 H-InvDB: SLC2A12

    Other Databases showing SLC2A12 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC2A12 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC2A12 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC2A12 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC2A12 gene:
    Search GeneIP for patents involving SLC2A12

    GeneCards and IP:
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