SLC2A11 Gene
protein-coding GIFtS: 50
GCID: GC22P024198
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solute carrier family 2 (facilitated glucose transporter),...
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Aliases
for SLC2A11 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 111 2 | | SLC2A11-A1 | | GLUT101 2 3 | | SLC2A11-C1 | | GLUT111 2 3 | | Facilitative Glucose Transporter GLUT112 | | Glucose Transporter Type 102 3 | | Glucose Transporter Protein 102 | | Glucose Transporter Type 112 3 | | Glucose Transporter Protein 112 | | GLUT-102 3 | | Glucose Transporter-Like Protein XI2 | | GLUT-112 3 | | Solute Carrier Family 2, Facilitated Glucose Transporter Member 112 |
Export aliases for SLC2A11 gene to outside databasesPrevious GC identifers: GC22U990207 GC22P020895 GC22P022523 GC22P007184 |
Summaries
for SLC2A11 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SLC2A11:
SLC2A11 belongs to a family of plasma membrane proteins that mediate transport of sugars across the membrane byfacilitative diffusion (Sasaki et al., 2001 (PubMed 11741323)).(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: GTR11_HUMAN, Q9BYW1Function: Facilitative glucose transporter
Gene Wiki entry for SLC2A11
|
Genomic Views
for SLC2A11 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SLC2A11 gene promoter:
NF-1 RFX1 Elk-1 p300 HTF Lmo2 En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SLC2A11
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC2A11 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q11.23 Ensembl cytogenetic band: 22q11.23 HGNC cytogenetic band: 22q11.23SLC2A11 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P024198: view genomic region
(about GC identifiers)
Start:
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24,198,890 bp from pter |
End:
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24,227,740 bp from pter |
Size:
|
28,851 bases |
Orientation:
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plus strand |
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Proteins
for SLC2A11 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: GTR11_HUMAN, Q9BYW1 (See
protein sequence)Recommended Name: Solute carrier family 2, facilitated glucose transporter member 11 Size: 496 amino acids; 53703 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Caution: Has been described as GLUT10 in litterature, but this gene name has already been used for SLC2A10
Secondary accessions: E9PH55 Q542Y4 Q6ICJ5 Q8WXF9 Q8WYM4Alternative splicing: 4 isoforms: Q9BYW1-1 Q9BYW1-2 Q9BYW1-3 Q9BYW1-4 Explore the universe of human proteins at neXtProt for SLC2A11: NX_Q9BYW1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BYW1
SLC2A11 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001020109.1 NP_001020110.1 NP_110434.3
ENSEMBL proteins: ENSP00000342542 ENSP00000385949 ENSP00000381399 ENSP00000384987 ENSP00000255830 ENSP00000403654 ENSP00000398439 ENSP00000398746 ENSP00000385156 ENSP00000326748 Reactome Protein details: Q9BYW1
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
TAS | -- | | GO:0016021 | integral to membrane |
IEA | -- |
SLC2A11 for ontologies About GeneDecksing
SLC2A11 Antibody Products:
Assay Products for SLC2A11: |
Protein
Domains /
Families
for SLC2A11 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SLC2A11 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BYW1ProtoNet protein and cluster: Q9BYW1 3 Blocks protein families: IPB000803 Mammalian facilitated glucose transporter family signature IPB003663 Sugar transporter signature IPB005829 Sugar transporter superfamily
UniProtKB/Swiss-Prot: GTR11_HUMAN, Q9BYW1Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transportersubfamily |
Function
for SLC2A11 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: GTR11_HUMAN, Q9BYW1Function: Facilitative glucose transporter
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC2A11 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC2A11 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): SLC2A11 (NM_001024939) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC2A11 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC2A11 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC2A11 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0022857 | transmembrane transporter activity |
-- | -- | | GO:0022891 | substrate-specific transmembrane transporter activity |
IEA | -- |
SLC2A11 for ontologies About GeneDecksing
|
Pathways & Interactions
for SLC2A11 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | SLC-mediated transmembrane transport | | | 2 | Facilitative Na+-independent glucose transporters | | | 3 | HIF1Alpha Pathway | | | 4 | PAK Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for SLC2A11
5 
Reactome Pathways for SLC2A11
SLC2A11 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC2A11
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008643 | carbohydrate transport |
IEA | -- | | GO:0055085 | transmembrane transport |
TAS | -- |
SLC2A11 for ontologies About GeneDecksing
|
Drugs & Compounds
for SLC2A11 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SLC2A11 for compounds About GeneDecksing
 Browse Tocris compounds for SLC2A11
2 Novoseek chemical compound relationships for SLC2A11 gene About this table
Search CenterWatch for drugs/clinical trials and news about SLC2A11 / GTR11
|
Transcripts
for SLC2A11 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SLC2A11 gene (3 alternative transcripts): NM_001024938.2 NM_001024939.2 NM_030807.3 Unigene Cluster for SLC2A11: Solute carrier family 2 (facilitated glucose transporter), member 11 Hs.743282 [show with all ESTs]Unigene Representative Sequence: NM_03080718/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22): ENST00000345044 ENST00000403208 ENST00000398356(uc002zym.4 uc002zyn.4 uc002zyo.4 uc011ajc.1)
ENST00000405847 ENST00000467660 ENST00000405286 ENST00000255830 ENST00000489322
ENST00000440493 ENST00000473740 ENST00000492516 ENST00000423972 ENST00000418102
ENST00000491948 ENST00000436643 ENST00000405340(uc011ajd.1 uc002zyp.4)
ENST00000461809(uc002zyl.1) ENST00000316185
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC2A11 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC2A11 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): SLC2A11 (NM_001024939) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC2A11 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC2A11 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC2A11
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SLC2A11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC2A11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC2A11 |
Additional cDNA sequence: AF443201.1 AF479409.1 AJ271290.1 AK075467.1 AK092466.1 AK296169.1 AK300196.1 AK304409.1 AK308589.1 AK308602.1 AK314502.1 AK315937.1 AK316049.1 BC018967.2 BC063525.1 BC094735.1 BC100807.2 BC100808.2 BC100809.1 BC100810.1 CR456373.1 23 DOTS entries: DT.207976 DT.100815892 DT.100774696 DT.100774695 DT.91831356 DT.120669483 DT.120669443 DT.422844 DT.100831126 DT.120669343 DT.95270457 DT.97825700 DT.40118809 DT.120669437 DT.100689855 DT.120669418 DT.92419647 DT.100748967 DT.120669247 DT.120669265 DT.120669380 DT.97817953 DT.100748966 1476 AceView cDNA sequences (see top 24): AA295918 CB140254 AF469046 AI143165 BQ678068 AI494296 AW160393 AJ711116 BE382319 CD675471 BM844224 CR617581 AA371583 BM673167 CN482296 R68633 BE645161 BE222900 BU501084 Z23063 AW027535 CB111053 CB120074 BM769836 BU786775 BG340350 BF438989 BG765632 BQ069049 AI350332 AI918101 AF479409 BF061812 AI261418 CB128882 AI348574 BM928804 BI086848 BM551894 BP429166 BC008914 AI215687 BQ949963 BM696446 BM505227 CB851923 BU735071 CD674818 BM021480 BM850110 AW630016 CD106299 BM510629 CB127256 AI669946 BQ084139 CB989442 BQ652740 BM511463 CD172285 H46251 BQ646350 BI252196 AI697884 BM825455 NM_002415 AA028035 AI128231 AI674639 AI084213 R71917 AW009652 BM507190 BM051673 BM888453 AI671928 BU077824 AI087205 CB122890 AI219290 AI363384 CR606770 BI227009 AA181313 BE386097 BE269667 CB111707 AW163668 BM311441 CR602271 AA157884 BQ684691 AW009548 BC007676 AI417316 BE561288 BM055335 AW193906 BF338724 CA432812 BM838749 BQ279063 BM759059 BU500107 BU781868 AW341527 BU754406 AI360346 BC018967 CB156328 BE793353 AI291272 BI192804 CN484532 BQ062010 CR456373 BX378828 BF940111 CB108556 BM824569 BM827193 AI073931 BU737717 H23821 AW005755 BG476993 CB992960 CR456520 CA394825 BX328665 AI768768 AI348590 BF724617 CA411785 BC022414 BM672514 BF221646 BE348447 H44219 CA445192 BM790442 AA740570 AW341498 H45380 AI553869 CD108658 BQ064232 BM740625 BU174015 BQ220293 AW054836 BU857808 AW163333 BM743200 AI336268 BU190643 AI816177 CA418623 BE794339 AI298814 BC000447 BM310573 BE791073 BM824880 BM565460 BE888301 BE278306 BF689735 BC053376 AI816216 BM699364 BU179712 BF432610 BQ063218 BF112251 AI347489 BM841148 AW071866 CB122932 AA721058 BM666811 AI744576 AI688975 BM557522 BU070428 BM931452 BQ922381 BE312186 BF111661 BE796702 AA356788 BU185117 BU787927 AI669124 BM687377 BU838070 CB068312 AI807688 BQ061588 AJ271290 BQ083935 AW246102 BU185062 AV704512 BU789064 BE790554 BE326472 AW468709 BU857402 BQ648978 BX349504 BE274480 BE794540 CB160664 BM504318 BG168686 BQ961643 AI339470 N92307 BU075681 BG180275 AI869963 BM808120 BC013976 BU620040 AI816284 BM695027 AI091605 BG282075 CB160659 BE675356 BU145285 BU157752 BC063525 CD676270 AW006424 BX343542 CD674111 BM747417 M95775 BU174305 AK075467 BU556978 AI694069 AI937168 BM792713 BM695453 BQ957590 AA340622 BE504759 AI299216 BU077454 BQ787442 BI966846 BX093983 BM887899 AI284494 BX333470 AI569755 AA452452 CF994516 AI193679 BI832039 BE206929 AI091708 BM128240 AW058662 AA339628 BU682534 BQ681639 BG104600 BM766852 BE408794 BM541392 BX283177 CF127001 AF443201 BQ647472 BU634019 AI085922 BC007376 CD216757 BM686387 AA863234 BM705559 AW005104 BU688942 AI470121 CB128124 BV199481 AW161213 AI308981 BE392596 H50429 CB125517 BM664604 AI915138 BM010532 BM021203 CB109030 H01089 AI090698 AW328112 BM821826 BM746711 AI221389 CK905453 N20231 AI719640 CB111073 BF207148 AI553989 BF439521 BQ446968 AA352598 BP429201 AI097535 AI760355 BM672117 BG749201 C04098 AL598366 CN484465 BU787651 AI215754 BG745033 BF060674 R27395 BQ581196 BF102601 BX371240 AI004980 AI936457 BG436668 AI797641 BI224826 AI200226 AI924344 BU602243 BG769480 BF968893 AW384484 CR541651 BG685630 AI868940 BX332511 BE745557 AI083693 BU539504 BG281749 BE278711 BQ278700 AI079453 CA338169 CB960556 BT007148 BX491228 BG327452 BU599129 BE386584 AI917539 BM128523 CB959807 BG170461 BE255744 BF973852 BG336152 AI191583 CB961164 AI200435 AA316826 BM019214 CB410323 AI589691 AI308986 BG231931 BF475875 BE258468 BU928874 CD673891 H52405 BE621309 CR407644 R27396 AI560428 CB151696 BQ013259 R34174 AI672745 AA312096 AI348400 AI749843 BM423568 AI369693 H43579 BM793171 BG475756 BU754550 BX347887 AI240121 BX340620 AI354843 BE397274 BU734848 BM849588 BG058579 AW779104 AI191831 CB160045 BM794428 BQ021036 BM745926 AX747559 BE268805 AI796755 BM796701 BX391183 AI626000 AI074437 CA437482 AA304865 AW071672 AI571374 AW592374 BI517325 AA312703 BU859676 AI831430 BE276331 BM712248 AI688520 BQ643694 CB124648 BF310675 BU596088 AI379834 BE019440 BI463097 BU617621 BG027436 AI223288 AI694828 BE795273 AW469660 BM727053 BP430559 BE389323 AW161476 BM703102 AA251135 BU741296 AI806435 BG750413 AI762932 AI279288 BF438882 BQ012300 AI435102 AI192754 BU928031 BG057653 BI601564 BP339207 BI819769 AI694829 AI819342 BI092306 CB128738 AI570422 CB121553 AV705587 AI215836 NM_030807 AW025191 AA299734 BM754129 CD674636 BE265372 BU500366 BM796596 BI199480 BF973778 AI193105 CF593306 BC051440 BE327076 CB146433 AI333815 AI283579 AI694274 BM851496 BX349503 BP429235 H20020 BM792773 AI702600 AI743598 BX391182 BX333518 AW139208 CB108624 CD674150 AA983827 AI184214 BI224696 AK055523 AI218757 BF128628 BG702376 BG113654 AA311908 AA888149 BI197958 BM053128 BI160632 AI278569 AI332690 AI367412 AI292007 BE744850 AW044101 BU595497 BU538576 AA814613 AI188345 BQ942463 CB106952 AA876359 BU151191 R66188 AI279799 BG744387 BE208482 CB110748 BM796935 AI283607 BE408116 BE619531 AI936584 BM808510 CB106729 AI190725 AI479689 AI743755 BE901411 BM686545 BI118155 BQ549357 BM555630 D12379 BM509625 BM817456 AW156879 AA340294 BM672775 BG769679 AI702756 AI311642 AI810523 BQ015582 BG333292 CB111216 AI091236 AI342970 AI864671 AI381538 BU960702 BM795923 BQ011703 BE264050 N40833 BM504083 BF792052 BI833308 BM670021 BE619845 L10612 BG330721 BQ650365 BX349750 CB961181 AI760395 BX329701 AI302171 BU600375 AI347466 CK005338 AI028497 AW027519 BG332793 AK092466 BE881199 AA370526 BP375917 BX385745 AA256146 BQ432198 AW510907 BE265445 AA906880 AI928829 AA909877 BQ879195 BI198477 H03322 AI338223 BU599267 AI590153 BE256405 BF195148 BM794785 BP431258 AI190207 AI247423 AA309830 BM687326 BF317334 BU594540 BU600157 AI369222 CD674774 BI160038 BF316554 T52634 N80939 CD674110 BM744640 BX100850 AW162060 AI040934 AI871246 BE738612 AI350225 BG256139 AI868523 AI949246 BM794946 AI313355 BM970254 AI344366 AI183270 AA890324 AA909609 BU688889 AA905485 AI017964 AA314002 AA150737 CF130141 BU536152 AA948629 AI929100 AA948630 AA719865 BE300930 BP429918 AW592118 BM044121 BG105084 AW469707 CB994322 AI699462 BG331286 BF684697 BU849984 AA991309 AW157533 AI688357 BU594892 BM833753 AA514961 BU600539 BP428794 W80925 BU598067 AI816444 BG332219 AI005144 H87907 CB160105 AI914972 BM083487 AI769467 AI374999 BU598521 AA032295 AI239684 BU155300 BG475821 AI040260 AI300451 BM707128 AV752952 AW183649 BM984896 CB149540 BM687770 BU077680 AW157611 AA147839 AI936849 AW161897 R65649 BF690279 AA768751 AI829626 AA340850 AI814123 BE390162 AA121539 AI435403 AI240040 AI286009 BM691915 BU602136 BQ025515 AI168029 BE395428 AI762471 BU787416 CA455511 AI374724 AA404728 AI333831 R48515 BM825107 AI191479 AW103187 AI243142 BF114710 BE614382 BE397306 AI636812 H20167 BF060675 AW004670 BE644913 BG168946 BQ652579 BU856952 CD676277 BU070162 BX379546 AI660589 AI215846 AI868771 AW328111 W69958 BU069923 BE277579 AA936466 AA329177 AI285345 AI453843 BG333242 BI603082 AI033906 AA470860 AA804564 R68632 BF219932 BU587734 BP374208 BF975494 BE856231 BE349171 AA643903 AA452420 BI468567 BI518261 AI702741 R64406 AA421707 R97730 AJ573977 BM791553 BU600652 BM798236 AI818569 AA493395 H87363 AI708875 BE392633 BF035878 AA404663 CD246305 BI192554 AA932751 N72006 BI757940 BU535301 AI218906 BU598454 AW803188 BU958069 BG330342 AA122330 BU595355 BE409487 CD174502 CD176574 CD173957 BU077826 CB051619 BU506562 CF135344 AI928607 AA973062 AA654000 AW272955 BE268238 CD173794 AW591987 BU587371 BI667319 AW157673 BI490625 AA596017 AA298107 BM808994 BU600936 BF679022 BF312874 AA746033 BI763496 R67718 BU594245 AA812303 AA906183 CD174500 AA453329 AA961067 AI800775 AI245575 BG282511 CD248255 AW263130 CA445027 AI269507 BU955028 BE468110 BG500346 H01088 BE796091 AA308706 AW295871 AW629369 N99435 BE622074 H81973 AA470780 BE277402 BU597233 H45448 AA460411 BI490105 AA931682 BQ023559 BE562985 W58087 AA559036 AA251199 AW183821 AW628768 BP352086 CD050960 AA480256 BE387441 AA614774 BX349502 AA055515 BG709094 CB990734 BM792435 BI759368 BI596319 AI742007 CD173164 AA431539 H92056 AA720837 BE909721 BU151627 BE899055 BU528368 CK125947 AI125853 CK126012 AI268153 BE261996 AA197276 BM919518 CD047972 AI857327 BU594923 BQ012463 AA939186 CD050063 AA995547 AW967149 AA156227 CD172929 CB139715 BU594454 CK003555 CD385472 AA527580 BP372303 AI203496 BP371921 AA451717 AW872484 BM564390 BU787695 BU596922 H45302 BM055053 CD174835 BU594843 BQ640372 BG029148 AA781516 AI817184 CB963330 BF968035 BE391292 BE514972 BI544744 BQ013288 BG256503 BQ890459 R96798 BE261156 H20356 CD250263 CD176118 AI084557 BU595398 BI762955 BU599553 AA885822 BQ224517 AI219695 AW197730 AI301984 AA146593 BI963044 CF780597 AA894802 CB993135 CD387409 AA603346 AA159488 AA504841 R67068 AW405873 H45991 BQ649754 AI827864 CD049972 AW170094 CK126020 AI344663 BI758945 AW081017 CB997309 BU599051 BE514637 BU957817 AA826455 BQ067002 AA150845 AA746599 W84589 H64815 W76668 AA909191 AA923568 AA143408 AA457623 BU595273 CD173111 BQ922004 BU190489 BQ438886 BU540350 AA115515 CD385068 AA045694 BI759366 AA971384 BU600961 BG777596 CD176689 M25639 AA987407 AI476653 BI667646 BG281986 AA577272 AV707022 AA523215 AI001778 AI826674 CD249542 BI860542 BU594323 BI823606 AI953250 BF218288 CD173784 CD175297 BI834395 AA994737 CD176952 AA045695 BU597599 AA527589 BE266814 BU588697 BF173296 CD048254 AA875959 AI027664 R25423 AI187084 BF930096 R26254 BG272968 CD387726 AA742472 AA588292 AA771804 AA025719 AI216427 AA573110 BI252814 CF130403 BG715033 BU598706 BE727466 AI382918 BG338268 AA810100 BI765529 BX389238 AA968458 AA962395 CD176556 BI755702 CB991748 R34296 AA255973 AA927016 CD172817 BP382615 T52384 BE727297 AA887230 CD172593 BG761404 BE264690 BG824586 BG771092 CB996799 BU600740 BG768454 AA065010 BF127426 BQ651174 BG477967 BM012889 BE280544 BI835592 CD175979 CD176327 AA885695 AA158706 AA902367 CD389444 AA974537 BG715675 BU599734 BE391596 CD173723 BQ920563 BI753901 CD176176 AA905064 CB961929 AI184992 BU564326 BM918809 CD174897 AW000833 AA459860 BU782782 CD248480 H20095 AA157572 AA535088 BU500349 AI200386 CD174519 T52307 CD248850 AA927323 BG900535 BG337679 CA455567 N29297 BI601179 AA160691 CD250030 AA613004 AA927299 AA918219 AA991419 BI517698 BG283369 AA961859 N24740 AA714841 BI837198 BU532234 H40095 CD050834 R73892 CD049352 BE409958 H03321 AI857302 BU945106 AA076332 BI198646 BG419229 AA629272 BI115665 AA055516 BX347886 CD176245 AA917588 AA078846 CB105931 AA524566 AA128551 BI753209 BE280194 AA707897 BE894161 CD249127 BU960358 AA128294 BG899679 BM856459 AI393363 N24760 W57954 AA641338 CD173819 BI763502 BG770248 AA032296 CD248771 BF103565 CB992654 AA961688 BQ084032 BF125462 BM738383 AA973552 AI222172 CD174388 W84608 BM683160 H52406 AA278211 BM911144 AI184010 AW958016 BI752737 BF874147 W80771 W24701 AI498977 AA953815 N72000 AI216034 W74201 AA970168 AA069807 BU599416 AA714341 AA459923 BI086455 CF619138 BU506556 BX340328 BG959772 D51431 AI810465 BI755029 BU839179 N57702 BM462680 BF431076 BE041446 AA906502 AA804946 BI465245 AI350306 CD388036 BG490405 BE898401 BG231430 BQ883653 W73080 BM083784 BF998866 H43578 BG150401 AA908363 CD051175 AI677731 AA205861 N30184 AA147279 AA897410 CB106083 CD250134 CD389596 AA912186 AA723423 BF030104 AL038046 AA757752 AI915687 N57761 BE391237 BU935502 H50190 BU963242 AA076109 AA983481 BQ647218 BE621753 AA580010 BE379493 AA860828 BU588893 BF692430 AA362290 AA150753 H02803 BQ936623 BU600769 BM805278 BU598794 AA969077 BU564090 BF685022 AW269010 AA147893 BU598466 BF211639 W69959 CD048800 CD048875 BQ892328 AA961974 AW304352 BE737631 AI291395 BG499697 AA516016 BG479967 BI764461 R63800 BF309484 BE264052 AA994385 AA939051 H81972 CD385660 AA121054 AA150889 AA991307 AA988526 H92079 AA961971 AA159446 BF871242 AA027224 R67027 BU855990 N99440 AW002198 AI267938 CD048416 AA027993 AA535872 AA148509 AA919055 AI222694 BQ674092 BI752492 AA878295 AA573141 AA844264 BQ676897 N26249 AI806689 N59094 BE314201 AA155650 BG615976 BU928575 AA455101 AW511898 AA159358 AA588265 AA167451 BG613557 AA625678 AW665949 AA629271 AV753443 AA962548 AA922165 AA908336 AA127849 AA628203 AI142647 AI239966 BQ892826 BG912673 AA765733 AA078847 AA026163 BU945051 AA909738 BU149497 BX370955 AI183658 H99715 AA491259 AA886201 AI358183 BE410896 AI027662 BU151053 BU597683 AA781675 AA927264 AA709182 BF305602 AA159892 AI673479 BG771070 BE295368 AA069287 AI937675 BM888092 BI517944 AI767633 BI838257 AA994166 BQ054738 BF306701 H64814 AA961858 W76318 AI796674 D53515 AA992236 AA584949 AA147232 AA922178 AA632302 AA888298 AA971757 AA938234 AI344398 AA075096 AA156403 BQ642544 BI225286 BU597738 BG477159 AA877528 BU603926 AA156617 AA505383 BG758726 BG826530 BU902549 H50428 BG538461 R71962 AA514596 AA187055 AI129704 BI116877 CD049965 BG827985 BM998292 AA610555 AI311399 CA455467 CD246564 AA972004 W16934 AA813660 AA157377 BM794134 BX328070 BU595555 BX368608 BF127833 BG497224 BE408744 BU598970 BF381930 AA464286 AA627655 H11210 AA654144 AI239548 BG996144 AJ714590 BQ346136 AA768220 AI038885 AI539695 BG260901 BE788397 AA513335 AI701691 R73983 CB997515 BP339367 AA151824 AI184204 AA935445 AA071027 CO248332 BF973923 AI470504 AW182149 BQ219420 BI869015 AA521116 BG099573 BU597531 CD248995 AA513426 BE622904 AI361194 BU535993 BF438777 BF699189 AI302948 BU600449 BI224758 BU535867 AI698827 AA897718 CD050521 AA872735 BE262621 BP429603 BE736859 BE207421 BU564727 BM904780 BE387303
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for SLC2A11 (see all 12) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | · | 15c | · |
|---|
|
| SP1: | | | | | - | | | | - | | - | | | | - | | | | | | - | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | - | | - | | | | - | | | | | | - | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | - | | - | | | | - | | | | | | - | | | | | | | | - | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | - | | | | - | | - | | | | - | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 15d |
|---|
|
| SP1: | | | |
| SP2: | | | |
| SP3: | | | |
| SP4: | | | |
| SP5: | | |
ECgene alternative splicing isoforms for SLC2A11
|
Expression
for SLC2A11 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SLC2A11 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGGTATGTG
About this image
See SLC2A11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC2A11
SOURCE GeneReport for Unigene cluster: Hs.743282
UniProtKB/Swiss-Prot: GTR11_HUMAN, Q9BYW1Tissue specificity: Expressed in heart and skeletal muscle
SABiosciences Custom PCR Arrays for SLC2A11
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC2A11
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SLC2A11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC2A11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC2A11 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC2A11 |
Orthologs
for SLC2A11 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SLC2A11 gene from 6/18 species (see all 18) About this table
ENSEMBL Gene Tree for SLC2A11 (if available)
TreeFam Gene Tree for SLC2A11 (if available) |
Paralogs
for SLC2A11 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SLC2A11 gene
- ENSG000002513572 SLC2A52 SLC2A72 SLC2A32 SLC2A92 SLC2A142 SLC2A22 SLC2A12
- SLC2A42
10 SIMAP similar genes for SLC2A11 using alignment to 13 protein entries: GTR11_HUMAN (see all proteins):SLC2A11-a SLC2A11-c SLC2A9 SLC2A5 SLC2A7 SLC2A14
SLC2A3 SLC2A1 SLC2A4 SLC2A2
SLC2A11 for paralogs About GeneDecksing
|
Genomic Variants
for SLC2A11 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SLC2A11 (24198890 - 24227740 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SLC2A11: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC2A11 |
|
Disorders
/ Diseases
for SLC2A11 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SLC2A11 for disorders About GeneDecksing
OMIM gene information: 610367
OMIM disorders: --
2  diseases for SLC2A11: About MalaCardsmeningioma leukemia
Human Genome Epidemiology (HuGE) Navigator: SLC2A11 (4 documents)
Export disorders for SLC2A11 gene to outside databases
|
Publications
for SLC2A11 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SLC2A11 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with SLC2A11) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning of a member of the facilitative glucose transporter gene family GLUT11 (SLC2A11) and identification of transcription variants. (PubMed id 11741323)1, 2, 9 Sasaki T.... Shimizu N. (2001)
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- Cloning and characterization of glucose transporter 11, a novel sugar transporter that is alternatively spliced in various tissues. (PubMed id 12175779)1, 2 Wu X.... Freeze H.H. (2002)
- Characterization of the human SLC2A11 (GLUT11) gene: alternative promoter usage, function, expression, and subcellular distribution of three isoforms, and lack of mouse orthologue. (PubMed id 16154905)1, 9 Scheepers A....Schurmann A. (2005)
- Characterization of human glucose transporter (GLUT) 11 (encoded by SLC2A11), a novel sugar-transport facilitator specifically expressed in heart and skeletal muscle. (PubMed id 11583593)1, 9 Doege H....Schurmann A. (2001)
- Multiple myeloma exhibits novel dependence on GLUT4, G LUT8, and GLUT11: implications for glucose transporter-directed therapy. (PubMed id 22452979)1 McBrayer S.K....Shanmugam M. (2012)
- Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)1 Han S....Kang D. (2010)
- Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)1 Rajaraman P....Inskip P.D. (2010)
|
External Searches for SLC2A11 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SLC2A11 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SLC2A11 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SLC2A11 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SLC2A11 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SLC2A11 gene:
Search GeneIP for patents involving SLC2A11
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SLC2A11 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SLC2A11 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC2A11 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC2A11 | | | OriGene Protein Over-expression Lysate for SLC2A11 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SLC2A11 | | OriGene 3'-UTR Clone for SLC2A11 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC2A11 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC2A11 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SLC2A11 | | OriGene Custom Protein Services for SLC2A11 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC2A11 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC2A11 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC2A11 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC2A11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC2A11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC2A11 |
| |
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| |  |  |  |  | | | | |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC2A11 |
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