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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC2A10 Gene

protein-coding   GIFtS: 54
GCID: GC20P045338

solute carrier family 2 (facilitated glucose transporter),...
 Explore 6 diseases affiliated with
SLC2A10 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC2A10    

Aliases
for SLC2A10 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 101 2
GLUT101 2 3 5
Glucose Transporter Type 102 3
GLUT-102 3
ATS2 5
Solute Carrier Family 2, Facilitated Glucose Transporter Member 102

External Ids:    HGNC: 134441   Entrez Gene: 810312   Ensembl: ENSG000001974967   OMIM: 6061455   UniProtKB: O955283   

Export aliases for SLC2A10 gene to outside databases

Previous GC identifers: GC20P045066 GC20P045976 GC20P046023 GC20P044771 GC20P042079


Summaries
for SLC2A10 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SLC2A10:
This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role
in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity
syndrome.(provided by RefSeq, Dec 2009)

UniProtKB/Swiss-Prot: GTR10_HUMAN, O95528
Function: Facilitative glucose transporter

Gene Wiki entry for SLC2A10


Genomic Views
for SLC2A10 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011362.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC2A10 gene promoter:
         RFX1   NCX/Ncx   FOXD3   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   POU2F1   POU2F1a   HSF2   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC2A10 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC2A10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC2A10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.1   Ensembl cytogenetic band:  20q13.12   HGNC cytogenetic band: 20q13.12

SLC2A10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC2A10 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P045338:  view genomic region     (about GC identifiers)

Start:
 45,338,126 bp from pter      End:
 45,364,986 bp from pter
Size:
 26,861 bases      Orientation:
 plus strand

Proteins
for SLC2A10 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: GTR10_HUMAN, O95528 (See protein sequence)
Recommended Name: Solute carrier family 2, facilitated glucose transporter member 10  
Size: 541 amino acids; 56911 Da
Subcellular location: Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region
Secondary accessions: A8K4J6 Q3MIX5 Q9H4I6

Explore the universe of human proteins at neXtProt for SLC2A10: NX_O95528

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O95528

    • SLC2A10 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_110404.1  
    ENSEMBL proteins: 
     ENSP00000352216  
    Reactome Protein details: O95528
    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: SLC2A10
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    Novus Biologicals SLC2A10 Protein
    Novus Biologicals SLC2A10 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SLC2A10

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0012505endomembrane system IEA--
    GO:0016021integral to membrane NAS11247674
    GO:0048471perinuclear region of cytoplasm IEA--


    SLC2A10 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SLC2A10

    Protein Domains /
    Families
    for SLC2A10 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC2A10 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR005829 Sugar_transporter_CS
     IPR005828 Sub_transporter
     IPR003663 Sugar/inositol_transpt
     IPR020846 MFS_dom
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry O95528

    ProtoNet protein and cluster: O95528

    2 Blocks protein families:
    IPB003663 Sugar transporter signature
    IPB005829 Sugar transporter superfamily


    UniProtKB/Swiss-Prot: GTR10_HUMAN, O95528
    Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter
    subfamily


    Function
    for SLC2A10 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: GTR10_HUMAN, O95528
    Function: Facilitative glucose transporter
    Biophysicochemical properties: Kinetic parameters: KM=0.28 mM for 2-deoxy-D-glucose;

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC2A10
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC2A10:
    hsa-miR-4324 hsa-miR-873 hsa-miR-509-5p hsa-miR-2110 hsa-miR-4330 hsa-miR-3065-5p hsa-miR-1827 hsa-miR-509-3-5p
    SwitchGear 3'UTR luciferase reporter plasmid: SLC2A10 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC2A10 (see all 7)
    OriGene shRNA RFP: SLC2A10
    OriGene siRNA: SLC2A10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC2A10

    Gene Editing
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC2A10 

    Cell Line
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    Search LifeMap BioReagents cell lines for SLC2A10

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005351sugar:hydrogen symporter activity NAS11247674


    SLC2A10 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SLC2A10:
     Decreased viability with pacli 

    Animal Models:
         5 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Slc2a10):
     cardiovascular system  hematopoietic system  immune system  renal/urinary system  respiratory system 

    SLC2A10 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for SLC2A10 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1SLC-mediated transmembrane transport
    		SLC-mediated transmembrane transport1.00
    		Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    		Transmembrane transport of small molecules0.50
    2Facilitative Na+-independent glucose transporters
    		Facilitative Na+-independent glucose transporters1.00
    3HIF1Alpha Pathway
    		HIF1Alpha Pathway1.00
    4PAK Pathway
    		Antioxidant Action of Vitamin-C0.56

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for SLC2A10
        Antioxidant Action of Vitamin-C
    HIF1Alpha Pathway

    4        Reactome Pathways for SLC2A10
        SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Facilitative Na+-independent glucose transporters



    SLC2A10 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC2A10

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015758glucose transport NAS11247674
    GO:0055085transmembrane transport TAS--


    SLC2A10 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC2A10 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC2A10 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC2A10
    1 Novoseek chemical compound relationship for SLC2A10 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glucose 49 29 18774132 (1), 16550171 (1), 16586067 (1), 18693279 (1) (see all 11)

    Search CenterWatch for drugs/clinical trials and news about SLC2A10 / GTR10 

    Transcripts
    for SLC2A10 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC2A10 gene: 
    NM_030777.3  

    Unigene Cluster for SLC2A10:

    Solute carrier family 2 (facilitated glucose transporter), member 10
    Hs.305971  [show with all ESTs]
    Unigene Representative Sequence: AF248053
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000359271(uc002xsl.3) ENST00000486000

    miRNA
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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC2A10:
    hsa-miR-4324 hsa-miR-873 hsa-miR-509-5p hsa-miR-2110 hsa-miR-4330 hsa-miR-3065-5p hsa-miR-1827 hsa-miR-509-3-5p
    SwitchGear 3'UTR luciferase reporter plasmid: SLC2A10 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC2A10 (see all 7)
    OriGene shRNA RFP: SLC2A10
    OriGene siRNA: SLC2A10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC2A10
    Clone
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    GenScript: all cDNA clones in your preferred vector: SLC2A10 (NM_030777)
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    Primer
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC2A10
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC2A10
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC2A10

    Additional cDNA sequence: 

    AF248053.1 AF321240.1 AF479407.1 AK055548.1 AK290961.1 AK315269.1 AL137188.3 BC101657.1 
    BC113423.1 

    7 DOTS entries:

    DT.412509  DT.95112248  DT.100767685  DT.120823140  DT.86835913  DT.92427962  DT.120823143 

    24/104 AceView cDNA sequences (see all 104):

    BP351705 BU739858 BX100500 BU676601 AI289525 W31204 AK055548 CK820177 
    BQ002484 AL137188 AI334230 BM720038 AW194341 BQ639648 AL449903 AU280287 
    CB053561 AF479407 NM_030777 AF321240 AL449909 BG563879 AA133497 AI240819 

    GeneLoc Exon Structure


    Expression
    for SLC2A10 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC2A10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCCAAATCGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SLC2A10 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainBlood Brain BarrierAdult Endothelial CellsBlood Brain Barrier, Endothelium
    Neural TubeNeural TubeSpinal Neural Tube CellsNeural Ectoderm
    Spinal CordPresumptive Spinal CordSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SLC2A10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC2A10

    SOURCE GeneReport for Unigene cluster: Hs.305971

    UniProtKB/Swiss-Prot: GTR10_HUMAN, O95528
    Tissue specificity: Widely expressed; highest levels in liver and pancreas

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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC2A10

    Orthologs
    for SLC2A10 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for SLC2A10 gene from 7/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SLC2A101 solute carrier family 2 (facilitated glucose transporter), more 64.69(n)
    61.38(a)    		   419206  XM_417383.3  XP_417383.2 
    lizard
    (Anolis carolinensis)    		 Reptilia SLC2A106
    		 --
    		 55(a)
    		 1 ↔ 1
    		 4(144703294-144710223)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.33282 Xenopus laevis transcribed sequence with weak similarity more 73.84(n)    48047084 
    zebrafish
    (Danio rerio)    		 Actinopterygii BM777825.12   -- 73.78(n)    BM777825.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT5G592501 D-xylose-proton symporter-like 3 44.11(n)
    37.88(a)    		   836043  NM_125315.4  NP_200733.2 
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 transporter family protein, putative, expressed
    transporter, major facilitator superfamily domain ...
    		 28(a)
    20(a)
    		 possible ortholog
    possible ortholog
    		 10(23023744-23028285)
    3(34547512-34553694)
    E. coli
    (Escherichia coli)    		 Gamma proteobacteria galP6
    araE6
    		 arabinose transporter
    		 27(a)
    25(a)
    		 many ↔ many
    many ↔ many
    		 Chromosome(3086306-3087700)
    Chromosome(2978786-2980204)


    ENSEMBL Gene Tree for SLC2A10 (if available)
    TreeFam Gene Tree for SLC2A10 (if available) 

    Paralogs
    for SLC2A10 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC2A10 gene
    SLC2A132  SLC2A122  
    9 SIMAP similar genes for SLC2A10 using alignment to 2 protein entries:     GTR10_HUMAN (see all proteins):
    SLC2A12    SLC2A7    SLC2A8    SLC2A14    SLC2A13    SLC2A5
    SLC2A1    SLC2A9    SLC2A2

    SLC2A10 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC2A10 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/614 NCBI SNPs in SLC2A10 are shown (see all 614)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 20 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs803582301,2
    		Cpathogenic42095160(+) GGGAGC/GAACTT 2 S R mis10--------
    rs803582291,2
    		Cpathogenic42095427(+) GGCTGA/GGCCAC 2 * W stg10--------
    rs780106741,2
    		F,--42077596(+) CTCCAT/CTGGGA 1 -- us2k11Minor allele frequency- C:0.35WA 118
    rs755327161,2
    		--42077991(+) CCCCAA/GCTATT 1 -- us2k10--------
    rs60179941,2
    		C--42078211(+) GATAAG/AGCTGC 1 -- us2k12Minor allele frequency- A:0.00NA 4
    rs2018394151,2
    		C--42078397(+) TCCTTC/TCCCAG 1 -- us2k10--------
    rs796720951,2
    		--42078792(+) CTCTGC/TTCAGA 1 -- us2k12Minor allele frequency- T:0.04CSA WA 120
    rs60944351,2
    		C,F,H,--42078961(+) CCCCTC/TCTAGA 1 -- us2k1 trp315Minor allele frequency- T:0.07NS EA WA NA 2336
    rs178610241,2
    		F--42079133(+) GTAGATGTGT   
      GTGT    /-    TGTGT     		1 -- us2k11Minor allele frequency- -:0.13EU 956
    rs731155541,2
    		C,--42079290(+) CCCCCA/CAGGGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SLC2A10 (45338126 - 45364986 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SLC2A10: --
    Human Gene Mutation Database (HGMD): SLC2A10

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for SLC2A10 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC2A10 for disorders           About GeneDecksing

    OMIM gene information: 606145   
    OMIM disorders: 208050  
    UniProtKB/Swiss-Prot: GTR10_HUMAN, O95528
  • Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS) [MIM:208050]. ATS is an autosomal
    • recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young
    age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association
    with facial features and several connective tissue manifestations such as soft skin and joint laxity.
    Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries

    6 diseases for SLC2A10:    About MalaCards
    arterial tortuosity syndrome    loeys-dietz syndrome    aortic aneurysm    tuberculosis
    malaria    mycobacterium tuberculosis

    2 diseases from the University of Copenhagen DISEASES database for SLC2A10:
    Arterial tortuosity syndrome     Loeys-Dietz syndrome
    Genetic Association Database (GAD): SLC2A10
    Human Genome Epidemiology (HuGE) Navigator: SLC2A10 (10 documents)

    Export disorders for SLC2A10 gene to outside databases

    Publications
    for SLC2A10 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC2A10 gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with SLC2A10)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary traits. (PubMed id 12941788)1, 2, 4, 9 Andersen G.... Pedersen O. (2003)
    2. Molecular cloning of a novel member of the GLUT family of transporters, SLC2A10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility. (PubMed id 11247674)1, 2, 3 McVie-Wylie A.J.... Chen Y.T. (2001)
    3. Evaluation of SLC2A10 (GLUT10) as a candidate gene for type 2 diabetes and related traits in Finns. (PubMed id 15936967)1, 4, 9 Mohlke K.L....Collins F.S. (2005)
    4. Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome. (PubMed id 16550171)1, 2, 9 Coucke P.J.... De Paepe A. (2006)
    5. Studies of relationships between the GLUT10 Ala206Thr polymorphism and impaired insulin secretion. (PubMed id 15975113)1, 4 Rose C.S....Hansen T. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    9. Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1. (PubMed id 11592815)1, 2 Dawson P.A....Bowden D.W. (2001)
    10. A novel missense and a recurrent mutation in SLC2A10 gene of patients affected with arterial tortuosity syndrome. (PubMed id 18774132)1, 9 Faiyaz-Ul-Haque M....Teebi A.S. (2009)

    External Searches for SLC2A10 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing SLC2A10 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 81031 HGNC: 13444 AceView: SLC2A10 Ensembl:ENSG00000197496 euGenes: HUgn81031
    ECgene: SLC2A10 H-InvDB: SLC2A10

    Other Databases showing SLC2A10 gene

    (According to HUGE)
    About This Section
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    Specialized Databases showing SLC2A10 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC2A10 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC2A10 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC2A10 gene:
    Search GeneIP for patents involving SLC2A10

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