Aliases
for SLC29A3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
Solute Carrier Family 29 (Equilibrative Nucleoside Transporter), Member
31 2 | | PHID2 | | ENT32 3 5 | | Equilibrative Nucleoside Transporter 32 | | Solute Carrier Family 29 (Nucleoside Transporters), Member 31 2 | | hENT33 | | HCLAP2 | | Solute Carrier Family 29 Member 33 | | HJCD2 | | |
| External Ids: | HGNC: 230961 | Entrez Gene: 553152 | Ensembl: ENSG000001982467 | OMIM: 6123735 | UniProtKB: Q9BZD23 |
|---|
|
Export aliases for SLC29A3 gene to outside databasesPrevious GC identifers: GC10P072971 GC10P072427 GC10P072423 GC10P072749 GC10P067074
Summaries
for SLC29A3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SLC29A3 Gene:
This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides,
nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is
characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and
hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has
also been associated with mutations at this locus. Alternatively spliced transcript variants have been
described.(provided by RefSeq, Mar 2010)
GeneCards Summary for SLC29A3 Gene: 
SLC29A3 (solute carrier family 29 (equilibrative nucleoside transporter), member 3) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with SLC29A3 include hypertrichosis, and hyperpigmentation, cutaneous, with hypertrichosis, hepatosplenomegaly, heart anomalies, hearing loss, and hypogonadism, and among its related super-pathways are Transmembrane transport of small molecules and Transport of organic anions. GO annotations related to this gene include nucleoside transmembrane transporter activity. An important paralog of this gene is SLC29A4.
UniProtKB/Swiss-Prot: S29A3_HUMAN, Q9BZD2Function: Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates
transport of adenine, adenosine and uridine, as well as several nucleoside analog drugs, such as anticancer and
antiviral agents, including cladribine, cordycepin, tubercidin and AZT. Does not transport hypoxanthine
 summary
for SLC29A3 Gene: Nucleoside transporters are divided into two families; the Na+-dependent solute carrier family 28 (SLC28)
and the equilibrative solute carrier family 29 (SLC29). SLC28 family transporters (CNT1-3) display
subtype-selective expression patterns; CNT1 is localized primarily to epithelial tissue whereas CNT2 and
CNT3 have more widespread distributions. SLC29 family transporters (ENT1-4) are glycosylated proteins,
localized to the plasma and mitochondrial membranes. They are expressed in the heart, brain, mammary gland,
erythrocytes and placenta, and also in fetal liver and spleen. They mediate nucleoside influx and efflux and
exhibit highest affinity for adenosine. CNT and ENT transporters play critical roles in nucleoside salvage
pathways where they mediate the first step of nucleotide biosynthesis. In addition, these transporters work
in concert to terminate adenosine signaling and are vital determinants in the response to a variety of
anticancer and antiviral treatments, as they modulate the entry of these nucleoside analogs into target
tissues.
|
Genomic Views
for SLC29A3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 73),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.2 NT_030059.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SLC29A3 gene promoter:
c-Fos AP-1 ATF-2 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for SLC29A3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC29A3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q22.1 Ensembl cytogenetic band: 10q22.1 HGNC cytogenetic band: 10q22.2SLC29A3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P073080: view genomic region
(about GC identifiers)
Start:
|
73,079,010 bp from pter |
End:
|
73,123,147 bp from pter |
Size:
|
44,138 bases |
Orientation:
|
plus strand |
ORGUL member locations:
Legend (see complete legend)
 |
Proteins
for SLC29A3 gene
(According to
UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MAXQB
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
|
UniProtKB/Swiss-Prot: S29A3_HUMAN, Q9BZD2 (See
protein sequence)Recommended Name: Equilibrative nucleoside transporter 3 Size: 475 amino acids; 51815 Da
Subcellular location: Membrane; Multi-pass membrane protein. Late endosome membrane. Lysosome membrane.
Note=Observed in a punctate intracellular pattern showing partial colocalization with late endosomes/lysosomes.
Not detected at the cell surface
Sequence caution: Sequence=BAA92041.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B2RB50 B4E2Z9 B7ZA37 Q0VAM9 Q5T465 Q7RTT8 Q8IVZ0 Q9BWI2 Q9NUS9Alternative splicing: 2 isoforms: Q9BZD2-1 Q9BZD2-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SLC29A3: NX_Q9BZD2
Explore proteomics data for SLC29A3 at MOPED
Post-translational modifications:
View modification sites using PhosphoSitePlusView neXtProt modification sites for NX_Q9BZD2
SLC29A3 Protein expression data from MOPED1, PaxDb2 and
MAXQB3 : About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001167569.1 NP_060814.4
ENSEMBL proteins: ENSP00000362285 Reactome Protein details: Q9BZD2
Human Recombinant Protein Products for SLC29A3:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SLC29A3 for ontologies About GeneDecksing
SLC29A3 Antibody Products:
Assay Products for SLC29A3: |
Protein
Domains /
Families
for SLC29A3 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| HGNC Gene Families:
SLC: Solute carriers
IUPHAR Guide to PHARMACOLOGY protein family classification: Equilibrative nucleoside transporter 3
SLC29 family
1 InterPro protein domain:Graphical View of Domain Structure for InterPro Entry Q9BZD2ProtoNet protein and cluster: Q9BZD2 1 Blocks protein domain: IPB002259 Delayed-early response protein/equilibrative nucleoside transporter signature
UniProtKB/Swiss-Prot: S29A3_HUMAN, Q9BZD2Similarity: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family
SLC29A3 for domains About GeneDecksing
|
Function
for SLC29A3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
Vector BioLabs,
and Sirion Biotech,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: S29A3_HUMAN, Q9BZD2Function: Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates
transport of adenine, adenosine and uridine, as well as several nucleoside analog drugs, such as anticancer and
antiviral agents, including cladribine, cordycepin, tubercidin and AZT. Does not transport hypoxanthineBiophysicochemical properties: Kinetic parameters: KM=1.86 mM for adenosine; KM=2.02 mM for uridine; pH
dependence: Optimum pH is 5.5 for adenosine uptake; Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005337 | nucleoside transmembrane transporter activity |
IEA | -- |
SLC29A3 for ontologies About GeneDecksing
Phenotypes:
5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Slc29a3):
SLC29A3 for phenotypes About GeneDecksing
Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for SLC29A3 | |  | Search LifeMap BioReagents cell lines for SLC29A3 | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC29A3 |
Pathways & Interactions
for SLC29A3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene).
About This Section
|
SuperPaths for SLC29A3 About See pathways by source
| SuperPath | Contained pathways About |
|---|
| 1 | SLC-mediated transmembrane transport | | | 2 | Transport of organic anions | | | 3 | Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane | |
Pathways by source See SuperPaths
Show all pathways
4 
Reactome Pathways for SLC29A3
SLC29A3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC29A3
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
SLC29A3 for ontologies About GeneDecksing
|
Drugs & Compounds
for SLC29A3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for SLC29A3 available from Tocris Bioscience About this table
1 HMDB Compound for SLC29A3 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Adenine | 1,6-Dihydro-6-iminopurine (see
all 19) | 73-24-5 | -- |
Search CenterWatch for drugs/clinical trials and news about SLC29A3 / S29A3
|
Transcripts
for SLC29A3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Sirion Biotech,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SLC29A3 gene (2 alternative transcripts): NM_001174098.1 NM_018344.5 Unigene Cluster for SLC29A3: Solute carrier family 29 (nucleoside transporters), member 3 Hs.438419 [show with all ESTs]Unigene Representative Sequence: NM_0011740983 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000373189(uc001jrs.4 uc001jrr.4 uc010qjq.2 uc001jrt.4)
ENST00000479577 ENST00000469204
Primer
Products: |  | OriGene qPCR primer pairs and template standards for SLC29A3
OriGene qSTAR qPCR primer pairs in human, mouse for SLC29A3
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC29A3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC29A3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC29A3 |
Additional mRNA sequence: AF326987.1 AK002022.1 AK096743.1 AK304503.1 AK314497.1 AK316152.1 AY288928.1 AY358686.1 BC000223.1 BC041575.1 BC050589.1 BC063019.1 BC120996.1 BC120997.1 NR_033413.1 NR_033414.1 9 DOTS entries: DT.454856 DT.92422109 DT.100796590 DT.100883283 DT.100001081 DT.97839501 DT.100883281 DT.121216132 DT.87077844 24/86 AceView cDNA sequences (see all 86): AI418098 AI653288 BC063019 AW473372 CA306540 AX775919 AI584067 CA306316 CA306308 AW189402 CR603307 AL523642 CB306048 CR602243 BC041575 BI767499 BX342389 CD629217 AU137690 AL540711 BM451417 BU159267 BM471958 CB154002
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SLC29A3 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c |
|---|
|
| SP1: | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | - | | | | - | | | | | | | | | | | | | | |
| SP4: | | | - | | | | - | | - | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SLC29A3
|
Expression
for SLC29A3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SLC29A3 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TCAAAGCCAT
About this image
See SLC29A3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC29A3
SOURCE GeneReport for Unigene cluster: Hs.438419
UniProtKB/Swiss-Prot: S29A3_HUMAN, Q9BZD2Tissue specificity: Widely expressed in both adult and fetal tissues. Highest levels in placenta, uterus, ovary,
spleen, lymph node and bone marrow. Lowest levels in brain and heart
SABiosciences Custom PCR Arrays for SLC29A3
Primer
Products: | | OriGene qPCR primer pairs and template standards for SLC29A3
OriGene qSTAR qPCR primer pairs in human, mouse for SLC29A3
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC29A3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC29A3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC29A3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC29A3 |
Orthologs
for SLC29A3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals and fungi.
Orthologs for SLC29A3 gene from 8/14 species (see all 14) About this table
ENSEMBL Gene Tree for SLC29A3 (if available)
TreeFam Gene Tree for SLC29A3 (if available) |
Paralogs
for SLC29A3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SLC29A3 gene
- SLC29A42 SLC29A12 SLC29A22
2 SIMAP similar genes for SLC29A3 using alignment to 1 protein entry: S29A3_HUMAN:SLC29A1 SLC29A2
SLC29A3 for paralogs About GeneDecksing
|
Genomic Variants
for SLC29A3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SLC29A3 (73079010 - 73123147 bp)
Structural Variations
Database of Genomic Variants (DGV) 1 variation for SLC29A3: About this table
Human Gene Mutation Database (HGMD): SLC29A3
Locus Specific Mutation Databases (LSDB): SLC29A3
| | SABiosciences Cancer Mutation PCR Assays |
| | SeqTarget long-range PCR primers for resequencing SLC29A3 |
|
Disorders
/ Diseases
for SLC29A3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
OMIM gene information: 612373
OMIM disorders: 612391
UniProtKB/Swiss-Prot: S29A3_HUMAN, Q9BZD2
Histiocytosis-lymphadenopathy plus syndrome (HLAS) [MIM:602782]: A syndrome characterized by the
combination of features from 2 or more of four histiocytic disorders, originally thought to be distinct:
Faisalabad histiocytosis (FHC), sinus histiocytosis with massive lymphadenopathy (SHML), H syndrome, and
pigmented hypertrichosis with insulin-dependent diabetes mellitus syndrome (PHID). FHC features include joint
deformities, sensorineural hearing loss, and subsequent development of generalized lymphadenopathy and swellings
in the eyelids that contain histiocytes. SHML causes lymph node enlargement in children frequently accompanied by
fever, leukocytosis, elevated erythrocyte sedimentation rate, and polyclonal hypergammaglobulinemia. H syndrome
is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and
hypogonadism; hearing loss is found in about half of patients. PHID is characterized by predominantly
antibody-negative insulin-dependent diabetes mellitus associated with pigmented hypertrichosis and variable
occurrence of other features of H syndrome. Note=The disease is caused by mutations affecting the gene
represented in this entry
19  diseases for SLC29A3: About MalaCardshypertrichosis hyperpigmentation, cutaneous, with hypertrichosis, hepatosplenomegaly, heart anomalies, hearing loss, and hypogonadism dysosteosclerosis pigmented hypertrichosis with insulin dependent diabetes mellitus syndrome
rhinoscleroma familial sinus histiocytosis with massive lymphadenopathy histiocytosis with joint contractures and sensorineural deafness polyclonal hypergammaglobulinemia
rosai-dorfman disease was-related disorders hypogonadism histiocytosis
sensorineural hearing loss diabetes mellitus short stature sinusitis
type 1 diabetes alzheimer's disease cervicitis
3 diseases from the University of Copenhagen DISEASES database for SLC29A3:Hypertrichosis Histiocytosis Rhinoscleroma
SLC29A3 for disorders About GeneDecksing
Congresses - knowledge worth sharing: 
Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015Genetic Association Database (GAD): SLC29A3
Human Genome Epidemiology (HuGE) Navigator: SLC29A3 (4 documents)
Export disorders for SLC29A3 gene to outside databases
|
Publications
for SLC29A3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SLC29A3 gene, integrated from 9 sources (see all 30):
(articles sorted by number of sources associating them with SLC29A3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoforms. (PubMed id 11396612)1, 2, 3 Hyde R.J.... Baldwin S.A. (2001)
- The H syndrome is caused by mutations in the nucleoside transporter hENT3. (PubMed id 18940313)1, 2, 9 Molho-Pessach V.... Zlotogorski A. (2008)
- Contribution of adenosine related genes to the risk o f depression with disturbed sleep. (PubMed id 20392501)1, 4 Gass N....Paunio T. (2010)
- The H syndrome: two novel mutations affecting the sam e amino acid residue of hENT3. (PubMed id 19889517)1, 2 Molho-Pessach V....Zlotogorski A. (2010)
- H syndrome: novel and recurrent mutations in SLC29A3. (PubMed id 20199539)1, 2 Priya T.P....Zlotogorski A. (2010)
- Human equilibrative nucleoside transporter-3 (hENT3) spectrum disorder mutations impair nucleoside transport, protein localization, and stability. (PubMed id 20595384)1, 2 Kang N....Govindarajan R. (2010)
- Mutations in SLC29A3, encoding an equilibrative nucle oside transporter ENT3, cause a familial histiocytosis syndrome (Faisalabad his tiocytosis) and familial Rosai-Dorfman disease. (PubMed id 20140240)1, 2 Morgan N.V....Maher E.R. (2010)
- [Relationship between single nucleotide polymorphism of the equilibrative nucleoside transporter ENT3 and susceptibility to lung can cer]. (PubMed id 20677642)1, 4 Li X....Zhou C. (2010)
- SLC29A3 gene is mutated in pigmented hypertrichosis w ith insulin-dependent diabetes mellitus syndrome and interacts with the insulin signaling pathway. (PubMed id 19336477)1, 2 Cliffe S.T....Buckley M.F. (2009)
- Mutations in the SLC29A3 gene are not a common cause of isolated autoantibody negative type 1 diabetes. (PubMed id 19581757)1, 4 Edghill E.L....Attersley A.T. (2009)
|
External Searches for SLC29A3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SLC29A3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SLC29A3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SLC29A3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SLC29A3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SLC29A3 gene:
Search GeneIP for patents involving SLC29A3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SLC29A3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC29A3 | | | QIAGEN SeqTarget long-range PCR primers for resequencing SLC29A3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC29A3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC29A3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC29A3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC29A3 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC29A3 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for SLC29A3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC29A3 |
| |  |  |  | | | | LSBio Antibodies in human, mouse, rat for SLC29A3 |
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Last full update: 23 Oct 2013 -
Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014
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