Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SLC29A1 Gene

protein-coding   GIFtS: 70
GCID: GC06P044187

Solute Carrier Family 29 (Equilibrative Nucleoside Transporter),...

(Previous names: solute carrier family 29 (nucleoside transporters), member...)
(Previous symbol: ENT1)
  See SLC29A1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Solute Carrier Family 29 (Equilibrative Nucleoside Transporter), Member
11 2
     Nucleoside Transporter, Es-Type2 3
ENT11 2 3 5     Solute Carrier Family 29 Member 12 3
Solute Carrier Family 29 (Nucleoside Transporters), Member 11 2     Equilibrative Nitrobenzylmercaptopurine Riboside (NBMPR)-Sensitive
Nucleoside Transporter2
Equilibrative NBMPR-Sensitive Nucleoside Transporter2 3     Equilibrative Nucleoside Transporter 12
Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside
Transporter2 3
     Solute Carrier Family 29, Member 12

External Ids:    HGNC: 110031   Entrez Gene: 20302   Ensembl: ENSG000001127597   OMIM: 6021935   UniProtKB: Q998083   

Export aliases for SLC29A1 gene to outside databases

Previous GC identifers: GC06P044189 GC06P044234 GC06P044295 GC06P043909


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for SLC29A1 Gene:
This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane
glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of
nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to
concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside
transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and
are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple
alternatively spliced variants, encoding the same protein, have been found for this gene. (provided by RefSeq,
Jul 2008)

GeneCards Summary for SLC29A1 Gene:
SLC29A1 (solute carrier family 29 (equilibrative nucleoside transporter), member 1) is a protein-coding gene. Diseases associated with SLC29A1 include pancreas adenocarcinoma, and pancreatic cancer. GO annotations related to this gene include nucleoside transmembrane transporter activity. An important paralog of this gene is SLC29A4.

UniProtKB/Swiss-Prot: S29A1_HUMAN, Q99808
Function: Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is
sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is
sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer
chemotherapeutics drugs)

summary for SLC29A1 Gene:
Nucleoside transporters are divided into two families; the Na+-dependent solute carrier family 28 (SLC28)
and the equilibrative solute carrier family 29 (SLC29). SLC28 family transporters (CNT1-3) display
subtype-selective expression patterns; CNT1 is localized primarily to epithelial tissue whereas CNT2 and
CNT3 have more widespread distributions. SLC29 family transporters (ENT1-4) are glycosylated proteins,
localized to the plasma and mitochondrial membranes. They are expressed in the heart, brain, mammary gland,
erythrocytes and placenta, and also in fetal liver and spleen. They mediate nucleoside influx and efflux and
exhibit highest affinity for adenosine. CNT and ENT transporters play critical roles in nucleoside salvage
pathways where they mediate the first step of nucleotide biosynthesis. In addition, these transporters work
in concert to terminate adenosine signaling and are vital determinants in the response to a variety of
anticancer and antiviral treatments, as they modulate the entry of these nucleoside analogs into target
tissues.

Gene Wiki entry for SLC29A1 (Equilibrative nucleoside transporter 1) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_007592.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC29A1 gene promoter:
         STAT1   Sp1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SLC29A1 promoter sequence
   Search Chromatin IP Primers for SLC29A1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC29A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.1   Ensembl cytogenetic band:  6p21.1   HGNC cytogenetic band: 6p21.1

SLC29A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC29A1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P044187:  view genomic region     (about GC identifiers)

Start:
44,187,242 bp from pter      End:
44,201,888 bp from pter
Size:
14,647 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: S29A1_HUMAN, Q99808 (See protein sequence)
Recommended Name: Equilibrative nucleoside transporter 1  
Size: 456 amino acids; 50219 Da
Secondary accessions: B3KQY5 Q5T9W9 Q9UJY2

Explore the universe of human proteins at neXtProt for SLC29A1: NX_Q99808

Explore proteomics data for SLC29A1 at MOPED

Post-translational modifications: 

  • Glycosylated1
  • Ubiquitination2 at Lys239, Lys249, Lys255, Lys356
  • Glycosylation2 at Asn48
  • Modification sites at PhosphoSitePlus

  • See SLC29A1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001071642.1  NP_001071645.1  NP_004946.1  NP_001071643.1  NP_001071644.1  

    ENSEMBL proteins: 
     ENSP00000392668   ENSP00000360820   ENSP00000360805   ENSP00000360796   ENSP00000360789  
     ENSP00000360778   ENSP00000360773   ENSP00000319152   ENSP00000377427   ENSP00000377424  
    Reactome Protein details: Q99808

    SLC29A1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for SLC29A1
    OriGene Protein Over-expression Lysate for SLC29A1
    OriGene MassSpec for SLC29A1
    OriGene Custom Protein Services for SLC29A1
    GenScript Custom Purified and Recombinant Proteins Services for SLC29A1
    Novus Biologicals SLC29A1 Protein
    Novus Biologicals SLC29A1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for SLC29A1 

    SLC29A1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for SLC29A1
    OriGene Custom Antibody Services for SLC29A1
    Novus Biologicals SLC29A1 Antibodies
    Abcam antibodies for SLC29A1
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for SLC29A1
    LSBio Antibodies in human, mouse, rat for SLC29A1

    SLC29A1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SLC29A1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SLC29A1
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for SLC29A1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Equilibrative nucleoside transporter 1
    SLC29 family

    2 InterPro protein domains:
     IPR002259 Eqnu_transpt
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q99808

    ProtoNet protein and cluster: Q99808

    1 Blocks protein domain: IPB002259 Delayed-early response protein/equilibrative nucleoside transporter signature

    UniProtKB/Swiss-Prot: S29A1_HUMAN, Q99808
    Similarity: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family


    Find genes that share domains with SLC29A1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S29A1_HUMAN, Q99808
    Function: Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is
    sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is
    sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer
    chemotherapeutics drugs)
    Biophysicochemical properties: Kinetic parameters: KM=0.62 mM for adenosine; Note=Vmax for adenosine uptake is
    about the same for SLC29A1 and SLC29A2;

         Genatlas biochemistry entry for SLC29A1:
    solute carrier family 29,member A1,equilibrative nucleoside transporter,widely distributed

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005337nucleoside transmembrane transporter activity IEA--
         
    Find genes that share ontologies with SLC29A1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC29A1:
     Increased gamma-H2AX phosphory 

         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Slc29a1):
     behavior/neurological  growth/size/body  nervous system  no phenotypic analysis 

    Find genes that share phenotypes with SLC29A1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Slc29a1tm1Msg for SLC29A1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC29A1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SLC29A1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC29A1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC29A1

    miRNA
    Products:
        
    miRTarBase miRNAs that target SLC29A1:
    hsa-mir-124-3p (MIRT022638), hsa-mir-1 (MIRT023775), hsa-mir-16-5p (MIRT031668)

    Block miRNA regulation of human, mouse, rat SLC29A1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLC29A1 (see all 9):
    hsa-miR-34b* hsa-miR-29b-1* hsa-miR-146a* hsa-miR-124 hsa-miR-298 hsa-miR-506 hsa-miR-2114* hsa-miR-449c
    SwitchGear 3'UTR luciferase reporter plasmidSLC29A1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SLC29A1
    Predesigned siRNA for gene silencing in human, mouse, rat SLC29A1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SLC29A1

    Clone
    Products:
         
    OriGene clones in human, mouse for SLC29A1 (see all 30)
    OriGene ORF clones in mouse, rat for SLC29A1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): SLC29A1 (NM_001078177)
    Sino Biological Human cDNA Clone for SLC29A1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC29A1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC29A1
    Addgene plasmids for SLC29A1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SLC29A1
    Browse ESI BIO Cell Lines and PureStem Progenitors for SLC29A1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC29A1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    S29A1_HUMAN, Q99808: Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass
    membrane protein. Note=Predominantly localized in the basolateral membrane in polarized MDCK cells
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol4
    nucleus4
    extracellular2
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral component of plasma membrane TAS8986748
    GO:0016020membrane TAS8986748
    GO:0016021integral component of membrane ----
    GO:0016323basolateral plasma membrane IDA12527552

    Find genes that share ontologies with SLC29A1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for SLC29A1 About   (see all 7)  
    See pathways by source

    SuperPathContained pathways About
    1Pyrimidine metabolism
    Fluoropyrimidine Activity0.69
    Fluoropyrimidine Pathway, Pharmacokinetics0.69
    2Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    SLC-mediated transmembrane transport0.47
    Transmembrane transport of small molecules0.47
    3Transport of vitamins, nucleosides, and related molecules
    Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane0.00
    Transport of vitamins, nucleosides, and related molecules
    4One carbon pool by folate
    Thiopurine Pathway, Pharmacokinetics/Pharmacodynamics0.34
    5RNA Polymerase I Promoter Opening
    Alcoholism0.34


    Find genes that share SuperPaths with SLC29A1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for SLC29A1
        Fluoropyrimidine Activity


    1 Reactome Pathway for SLC29A1
        Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane

    3 PharmGKB Pathways for SLC29A1
        Fluoropyrimidine Pathway, Pharmacokinetics
    Gemcitabine Pathway, Pharmacodynamics
    Thiopurine Pathway, Pharmacokinetics/Pharmacodynamics

    1 Kegg Pathway  (Kegg details for SLC29A1):
        Alcoholism

        Pathway & Disease-focused RT2 Profiler PCR Array including SLC29A1: 
              Drug Transporters in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for SLC29A1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for SLC29A1 (Q998081, 2, 3 ENSP000003607734) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000206342P498421, 2, 3, ENSP000003728174EBI-347907,EBI-347581 MINT-62585 MINT-62759 MINT-62683 I2D: score=5 STRING: ENSP00000372817
    ENSG00000226033P498421, 2, 3EBI-347907,EBI-347581 MINT-62585 MINT-62759 MINT-62683 I2D: score=5 
    ENSG00000226257P498421, 2, 3EBI-347907,EBI-347581 MINT-62585 MINT-62759 MINT-62683 I2D: score=5 
    ENSG00000234947P498421, 2, 3EBI-347907,EBI-347581 MINT-62585 MINT-62759 MINT-62683 I2D: score=5 
    ENSG00000236250P498421, 2, 3, ENSP000003917984EBI-347907,EBI-347581 MINT-62585 MINT-62759 MINT-62683 I2D: score=5 STRING: ENSP00000391798
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006139nucleobase-containing compound metabolic process TAS8986748
    GO:0006810transport ----
    GO:0007595lactation IEA--
    GO:0015858nucleoside transport IDA12527552
    GO:0015862uridine transport IEA--

    Find genes that share ontologies with SLC29A1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Compounds for SLC29A1 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    DipyridamoleAdenosine transport inhibitor[58-32-2]
    NBMPREquilibrative nucleoside transporter 1 (ENT1) inhibitor[38048-32-7]
    Dilazep dihydrochlorideAdenosine uptake inhibitor[20153-98-4]
    Decynium 22PMAT inhibitor[977-96-8]

    1 HMDB Compound for SLC29A1    About this table
    CompoundSynonyms CAS #PubMed Ids
    SodiumSodium (see all 2)7440-23-5--

    Selected DrugBank Compounds for SLC29A1 (see all 11)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    GemcitabinedFdC (see all 4)95058-81-4transportersubstrate20082300 16818276
    RibavirinRBV (see all 4)36791-04-5transportersubstrate20096989 20185188
    CytarabineAra-C (see all 26)147-94-4transportersubstrate20082300
    DidanosineDDI (see all 2)69655-05-6transporter--11463208
    FludarabineFAMP (see all 4)75607-67-9transportersubstrate20082300
    Fluorouracil5-Fluorouracil (see all 6)51-21-8transportersubstrate17695509
    PemetrexedLY231514 (see all 2)150399-23-8enzymeinducer21336182
    Troglitazone-- 97322-87-7targetinhibitor15963471
    Uridine-- 58-96-8transporter--16818276
    ZalcitabineDDC (see all 3)7481-89-2transporter--11463208

    8 IUPHAR Ligands for SLC29A1 (Equilibrative nucleoside transporter 1)    About this table
    LigandTypeActionAffinityPubmed IDs
    NBTI
    InhibitorInhibition9.7--
    draflazine
    InhibitorInhibition9.5--
    KF24345
    InhibitorInhibition9.414634039
    NBTGR
    InhibitorInhibition9.3--
    [3H]NBTI
    NoneNone9.3--
    dilazep
    InhibitorInhibition9--
    dipyridamole
    InhibitorInhibition8.5--
    [14C]adenosine
    NoneNone8.5--

    Selected Novoseek inferred chemical compound relationships for SLC29A1 gene (see all 29)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    nitrobenzylthioinosine 95.3 10 15081020 (2), 8093099 (1), 11085929 (1), 10366666 (1) (see all 8)
    5-(saenta-x8)fluorescein 93.7 3 8432200 (2), 9207471 (1)
    nucleoside 93.5 269 12724623 (4), 19801629 (4), 8432200 (3), 15102528 (3) (see all 99)
    draflazine 90.6 2 18462193 (1), 17379602 (1)
    soluflazine 89.6 2 18462193 (1), 17379602 (1)
    saenta 87.8 1 11849208 (1)
    deoxycytidine 85.9 18 15471562 (2), 16585222 (1), 17224927 (1), 17296311 (1) (see all 16)
    gemcitabine 80.4 37 15501974 (2), 16585222 (2), 19318496 (2), 15471562 (2) (see all 28)
    dipyridamole 79.9 18 17636949 (3), 18462193 (1), 19748575 (1), 15644498 (1) (see all 10)
    uridine 75.2 9 17121826 (2), 10722669 (1), 12416024 (1), 15043160 (1) (see all 6)

    2 PharmGKB related drug/compound annotations for SLC29A1 gene    About this table
    Drug/compound PharmGKB Annotation
    gemcitabineCA  
    paclitaxelCA  



    Find genes that share compounds with SLC29A1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SLC29A1 gene (5 alternative transcripts): 
    NM_001078174.1  NM_001078177.1  NM_004955.2  NM_001078175.2  NM_001078176.2  

    Unigene Cluster for SLC29A1:

    Solute carrier family 29 (nucleoside transporters), member 1
    Hs.25450  [show with all ESTs]
    Unigene Representative Sequence: NM_001078177
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000427851 ENST00000371755(uc003owy.1) ENST00000371740(uc003owx.1)
    ENST00000371731 ENST00000371724 ENST00000371713 ENST00000371708 ENST00000472176(uc011dvq.1)
    ENST00000313248 ENST00000393844(uc021yzw.1 uc011dvp.1 uc003owu.1 uc003owv.1 uc003oww.1)
    ENST00000393841(uc003owz.1 uc021yzx.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SLC29A1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLC29A1 (see all 9):
    hsa-miR-34b* hsa-miR-29b-1* hsa-miR-146a* hsa-miR-124 hsa-miR-298 hsa-miR-506 hsa-miR-2114* hsa-miR-449c
    SwitchGear 3'UTR luciferase reporter plasmidSLC29A1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SLC29A1
    Predesigned siRNA for gene silencing in human, mouse, rat SLC29A1
    Clone
    Products:
         
    OriGene clones in human, mouse for SLC29A1 (see all 30)
    OriGene ORF clones in mouse, rat for SLC29A1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): SLC29A1 (NM_001078177)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC29A1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC29A1
    Addgene plasmids for SLC29A1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SLC29A1
    OriGene qSTAR qPCR primer pairs in human, mouse for SLC29A1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLC29A1
      QuantiTect SYBR Green Assays in human, mouse, rat SLC29A1
      QuantiFast Probe-based Assays in human, mouse, rat SLC29A1

    Additional mRNA sequence: 

    AB490708.1 AB490709.1 AF079117.1 AK090491.1 AK090615.1 AK293558.1 AK304285.1 BC001382.2 
    BC008954.2 BC095398.1 U81375.1 

    Selected DOTS entries (see all 29):

    DT.100677517  DT.100647849  DT.416615  DT.416616  DT.100677515  DT.92450528  DT.95349688  DT.97847963 
    DT.92450530  DT.100677507  DT.95358664  DT.100677519  DT.95358661  DT.95358669  DT.100677504  DT.95358681 
    DT.100852953  DT.95204966  DT.95358670  DT.92450518  DT.95212146  DT.100677512  DT.121317670  DT.121317712 

    Selected AceView cDNA sequences (see all 419):

    BM661584 CB959522 AA766232 CR593431 CR625059 CB961939 BP375132 CR623545 
    AK090491 BQ773630 BI758137 BM904389 AK090615 CR621028 BQ218503 BQ083557 
    BE280829 BI225991 BP344467 BP375158 BE313496 AF079117 CA413882 CR593933 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SLC29A1 (see all 32)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c · 11d · 11e ^ 12a ·
    SP1:                                      -           -     -     -     -     -     -     -     -     -     -                                                   
    SP2:                                                                                -     -           -     -                                                   
    SP3:                                      -     -     -     -     -     -     -     -     -     -     -     -                                                   
    SP4:                                      -     -     -     -     -     -     -     -     -     -     -     -                                                   
    SP5:                                                              -     -     -     -     -     -     -     -                                                   

    ExUns: 12b · 12c · 12d · 12e · 12f · 12g · 12h ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17a · 17b ^ 18a · 18b ^ 19a · 19b ^ 20a · 20b · 20c ^ 21 ^ 22a · 22b ·
    SP1:                    -     -     -     -     -     -                                         -     -                                                         
    SP2:                    -     -     -     -     -     -                                         -     -                                                         
    SP3:                    -     -     -     -     -     -                                         -     -                                                         
    SP4:                    -     -     -     -     -     -                                         -     -                                                         
    SP5:                    -     -     -     -     -     -                                         -     -                                                         


    ECgene alternative splicing isoforms for SLC29A1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SLC29A1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTAAAAAAA
    SLC29A1 Expression
    About this image


    SLC29A1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 6 entries
             HyStem+TGFbeta3+GDF5-induced SK11 cells
     
     Cartilage (Muscoskeletal System)    fully expand to see all 5 entries
             HyStem+TGFbeta3+GDF5-induced SK11 cells
     
     Thymus (Hematopoietic System)    fully expand to see all 2 entries
             Double Negative 2 Thymocytes Thymus
             Thymus
     
     Liver (Hepatobiliary System)
             Liver Lobule
     
     Umbilical Cord (Extraembryonic Tissues)
             Wharton's jelly-derived stem cells
    SLC29A1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC29A1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.25450

    UniProtKB/Swiss-Prot: S29A1_HUMAN, Q99808
    Tissue specificity: Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver
    and spleen

        Pathway & Disease-focused RT2 Profiler PCR Array including SLC29A1: 
              Drug Transporters in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SLC29A1
    OriGene qSTAR qPCR primer pairs in human, mouse for SLC29A1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLC29A1
    QuantiTect SYBR Green Assays in human, mouse, rat SLC29A1
    QuantiFast Probe-based Assays in human, mouse, rat SLC29A1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC29A1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC29A1 gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc29a11 , 5 solute carrier family 29 (nucleoside transporters), more1, 5 82.38(n)1
    80.04(a)1
      17 (22.59 cM)5
    639591  NM_001199113.11  NP_001186042.11 
     455852005 
    chicken
    (Gallus gallus)
    Aves SLC29A11 solute carrier family 29 (nucleoside transporters), more 68.09(n)
    61.8(a)
      421439  XM_004935390.1  XP_004935447.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC29A16
    solute carrier family 29 (equilibrative nucleoside...
    61(a)
    1 ↔ 1
    1(227837887-227905304)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC687322 hypothetical protein MGC68732 77.24(n)    BC060420.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003314391 equilibrative nucleoside transporter 1-like 67.92(n)
    69.72(a)
      100331439  XM_005172933.1  XP_005172990.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG119073
    Ent11
    equilibrative nucleoside transporter,
    nitrobenzyl-thioinosine-insensitive3
    Equilibrative nucleoside transporter 11
    32(a)
    (best of 2)3
    47.39(n)1
    35.18(a)1
      21C23
    332071  NM_164381.21  NP_722628.11 
    worm
    (Caenorhabditis elegans)
    Secernentea K09A9.33   -- 26(a)
    (best of 2)
      X(15636297-15638548)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes FUN261 FUN26 43.22(n)
    26.13(a)
      851211   NP_009380.1 


    ENSEMBL Gene Tree for SLC29A1 (if available)
    TreeFam Gene Tree for SLC29A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SLC29A1 gene
    SLC29A42  SLC29A32  SLC29A22  
    2 SIMAP similar genes for SLC29A1 using alignment to 4 protein entries:     S29A1_HUMAN (see all proteins):
    SLC29A2    SLC29A3

    Find genes that share paralogs with SLC29A1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SLC29A1 (see all 389)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0362224
    A colorectal cancer sample4--see VAR_0362222 I V mis40--------
    VAR_0362214
    A colorectal cancer sample4--see VAR_0362212 A T mis40--------
    rs37347011,2
    C,F,A,H--44185254(+) TGTCCC/TGCCTG 2 -- us2k117Minor allele frequency- T:0.08NS NA WA CSA EA 1141
    rs792410161,2
    C,F--44185264(+) GCTGCT/AGCCTG 2 -- us2k14Minor allele frequency- A:0.18CSA WA NA EA 360
    rs1150059271,2
    F--44185299(+) TCCTGC/TCCCTG 2 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1814531731,2
    --44185324(+) CCGCCA/GCCTGG 2 -- us2k10--------
    rs1865451051,2
    --44185408(+) TGGGGA/TGGCCT 2 -- us2k10--------
    rs1409988061,2
    --44185425(+) TGGACC/TGCCTG 2 -- us2k10--------
    rs1113039071,2
    C,F--44185448(+) AGGTTG/AGGCCC 2 -- us2k11Minor allele frequency- A:0.50NA 2
    rs575957901,2
    C,F--44185522(+) GATAAT/GCCTGG 2 -- us2k14Minor allele frequency- G:0.26WA NA 242

    HapMap Linkage Disequilibrium report for SLC29A1 (44187242 - 44201888 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for SLC29A1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv5282CNV Insertion18451855
    nsv462936CNV Loss19166990
    nsv524398CNV Loss19592680
    nsv885851CNV Loss21882294
    nsv885852CNV Loss21882294
    dgv6843n71CNV Loss21882294

    Human Gene Mutation Database (HGMD): SLC29A1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC29A1
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC29A1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 602193    OMIM disorders: --

    3 diseases for SLC29A1:    
    About MalaCards
    pancreas adenocarcinoma    pancreatic cancer    colorectal cancer

    1 disease from the University of Copenhagen DISEASES database for SLC29A1:
    Pancreatic cancer

    Find genes that share disorders with SLC29A1           About GenesLikeMe

    Selected Novoseek inferred disease relationships for SLC29A1 gene (see all 14)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    pancreatic cancer 59.3 6 16585222 (1), 18378536 (1), 18589402 (1), 18992248 (1) (see all 6)
    diabetes gestational 43.8 12 20032083 (4), 16688763 (3), 19193655 (1), 15272035 (1)
    leukemia 41.4 2 9207471 (1), 18279955 (1)
    adenocarcinoma 27.8 4 15501974 (1), 17390066 (1), 19318496 (1), 19214867 (1)
    acute leukemia 23 1 16609362 (1)
    pancreatic carcinoma 14.1 1 17695509 (1)
    nsclc 12.5 7 15471562 (2), 17658213 (2)
    tumors 9.19 1 16585222 (1)
    breast cancer 0 3 16965766 (1), 11801546 (1), 12912975 (1)
    hyperglycemia 0 1 19193655 (1)

    Genetic Association Database (GAD): SLC29A1
    Human Genome Epidemiology (HuGE) Navigator: SLC29A1 (15 documents)

    Export disorders for SLC29A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SLC29A1 gene, integrated from 10 sources (see all 228):
    (articles sorted by number of sources associating them with SLC29A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs. (PubMed id 8986748)1, 2, 3 Griffiths M.... Baldwin S.A. (Nat. Med. 1997)
    2. Characterization of ribavirin uptake systems in human hepatocytes. (PubMed id 20185188)1, 7, 9 Fukuchi Y.... Chiba K. (J. Hepatol. 2010)
    3. Expression of human equilibrative nucleoside transporter 1 (hENT1) and its correlation with gemcitabine uptake and cytotoxicity in mantle cell lymphoma. (PubMed id 16818276)1, 7, 9 MarcAc S....Colomer D. (Haematologica 2006)
    4. Optimizing pemetrexed-gemcitabine combination in patients with advanced non-small cell lung cancer: a pharmacogenetic approach. (PubMed id 21336182)1, 7 De Pas T.M....De Braud F. (J Thorac Oncol 2011)
    5. A Large-scale genetic association study of esophageal adenocarcinoma risk. (PubMed id 20453000)1, 4 Liu C.Y....Christiani D.C. (Carcinogenesis 2010)
    6. Single nucleotide polymorphisms of gemcitabine metabolic genes and pancreatic cancer survival and drug toxicity. (PubMed id 20028759)1, 4 Okazaki T....Li D. (Clin. Cancer Res. 2010)
    7. Gemcitabine metabolic and transporter gene polymorphisms are associated with drug toxicity and efficacy in patients with locally advanced pancreatic cancer. (PubMed id 20665488)1, 4 Tanaka M....Li D. (Cancer 2010)
    8. Population pharmacokinetics of gemcitabine and its metabolite in Japanese cancer patients: impact of genetic polymorphisms. (PubMed id 20608756)1, 4 Sugiyama E....Sawada J. (Clin Pharmacokinet 2010)
    9. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    10. Influence of a single nucleotide polymorphism at the main ribavirin transporter gene on the rapid virological response to pegylated interferon-ribavirin therapy in patients with chronic hepatitis C virus infection. (PubMed id 20812847)1, 4 Morello J....RodrA-guez-NA^voa S. (J. Infect. Dis. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 2030 HGNC: 11003 AceView: SLC29A1 Ensembl:ENSG00000112759 euGenes: HUgn2030
    ECgene: SLC29A1 Kegg: 2030 H-InvDB: SLC29A1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SLC29A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SLC29A1 gene:
    Search GeneIP for patents involving SLC29A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for SLC29A1   OriGene RNAi products in human, mouse, rat for SLC29A1  
     OriGene qPCR primer pairs and template standards for SLC29A1   OriGene Protein Over-expression Lysate for SLC29A1  
     OriGene MassSpec something-or-other for SLC29A1   OriGene clones in human, mouse for SLC29A1  
     OriGene qSTAR qPCR primer pairs in human, mouse for SLC29A1   OriGene Purified Protein for SLC29A1  
     OriGene ORF clones in mouse, rat for SLC29A1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SLC29A1   OriGene Custom Protein Services for SLC29A1  

     
     
     Block miRNA regulation of human, mouse, rat SLC29A1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SLC29A1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC29A1 Predesigned siRNA for gene silencing in human, mouse, rat SLC29A1
     QuantiFast Probe-based Assays in human, mouse, rat SLC29A1 QuantiTect SYBR Green Assays in human, mouse, rat SLC29A1
     PCR Arrays including human, mouse, rat SLC29A1 Search Chromatin IP Primers for SLC29A1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLC29A1  GeneGlobe Interaction Network for SLC29A1
     Regulatory tfbs in SLC29A1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SLC29A1 GenScript cDNA clones with any tag delivered in your preferred vector for SLC29A1
     GenScript Custom Assay Services for SLC29A1 GenScript Custom overexpressing Cell Line Services for SLC29A1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Tocris compounds for SLC29A1
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for SLC29A1
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SLC29A1 antibodies
     SLC29A1 proteins
     SLC29A1 lysates
     Antibodies for SLC29A1
     See all of Abcam's Antibodies, Kits and Proteins for SLC29A1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for SLC29A1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC29A1
     SwitchGear 3'UTR luciferase reporter plasmids for SLC29A1
     SwitchGear Promoter luciferase reporter plasmids for SLC29A1
     ThermoFisher Antibodies for SLC29A1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC29A1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC29A1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SLC29A1
     LSBio Antibodies in human, mouse, rat for SLC29A1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Addgene plasmids for SLC29A1
      Search eBioscience for proteins for SLC29A1
      Search eBioscience for elisas for SLC29A1
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SLC29A1 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4