Aliases for SLC26A7 Gene
External Ids for SLC26A7 Gene
Previous GeneCards Identifiers for SLC26A7 Gene
This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. This gene has abundant and specific expression in the kidney. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Aug 2013]
GeneCards Summary for SLC26A7 Gene
SLC26A7 (Solute Carrier Family 26 Member 7) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Salivary secretion. GO annotations related to this gene include chloride channel activity and sulfate transmembrane transporter activity. An important paralog of this gene is SLC26A3.
UniProtKB/Swiss-Prot for SLC26A7 Gene
Acts as a sodium-independent DIDS-sensitive anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. May play a role in the maintenance of the electrolyte and acid-base homeostasis in the kidney, by acting as a distal excretory segment-specific anion exchanger. Plays a major role in gastric acid secretion.