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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC26A6 Gene

protein-coding   GIFtS: 58
GCID: GC03M048664

Solute Carrier Family 26 (Anion Exchanger), Member 6

(Previous names: solute carrier family 26, member 6)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 26 (Anion Exchanger), Member 61 2     Sulfate Anion Transporter1 2
Solute Carrier Family 26, Member 61 2     Anion Exchange Transporter2
Pendrin-Like Protein 11 3     Solute Carrier Family 26 Member 62
Anion Transporter 11 2     Pendrin-L13
Pendrin L11 2     

External Ids:    HGNC: 144721   Entrez Gene: 650102   Ensembl: ENSG000002256977   OMIM: 6100685   UniProtKB: Q9BXS93   

Export aliases for SLC26A6 gene to outside databases

Previous GC identifers: GC03M048453 GC03M047946 GC03M048482 GC03M048623 GC03M048639 GC03M048640


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC26A6 Gene:
This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This
particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate.
Alternatively spliced transcript variants encoding distinct isoforms have been described. (provided by RefSeq,
Aug 2013)

GeneCards Summary for SLC26A6 Gene: 
SLC26A6 (solute carrier family 26 (anion exchanger), member 6) is a protein-coding gene. Diseases associated with SLC26A6 include acute urate nephropathy, and fainting, and among its related super-pathways are Transmembrane transport of small molecules and Amino acid and oligopeptide SLC transporters. GO annotations related to this gene include secondary active sulfate transmembrane transporter activity and chloride transmembrane transporter activity. An important paralog of this gene is SLC26A9.

UniProtKB/Swiss-Prot: S26A6_HUMAN, Q9BXS9
Function: Does not seem to be involved in anion transport

Gene Wiki entry for SLC26A6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_022517.18  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC26A6 gene promoter:
         FOXO4   NRSF form 1   HNF-4alpha2   NRSF form 2   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC26A6 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC26A6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC26A6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.3   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.31

SLC26A6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC26A6 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M048664:  view genomic region     (about GC identifiers)

Start:
48,663,156 bp from pter      End:
48,672,926 bp from pter
Size:
9,771 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: S26A6_HUMAN, Q9BXS9 (See protein sequence)
Recommended Name: Solute carrier family 26 member 6  
Size: 759 amino acids; 82967 Da
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: Q96Q90 Q9NQU1
Alternative splicing: 4 isoforms:  Q9BXS9-1   Q9BXS9-2   Q9BXS9-3   Q9BXS9-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC26A6: NX_Q9BXS9

Explore proteomics data for SLC26A6 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BXS9

  • SLC26A6 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC26A6 Protein Expression
    REFSEQ proteins (6 alternative transcripts): 
    NP_001035544.1  NP_001268661.1  NP_001268662.1  NP_075062.2  NP_599025.2  NP_602298.2  

    ENSEMBL proteins: 
     ENSP00000404684   ENSP00000378920   ENSP00000373239   ENSP00000307089   ENSP00000337648  
     ENSP00000401066   ENSP00000389922   ENSP00000404607   ENSP00000388721   ENSP00000387532  
     ENSP00000401813   ENSP00000405872   ENSP00000351597  
    Reactome Protein details: Q9BXS9
    Human Recombinant Protein Products for SLC26A6: 
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    Cloud-Clone Corp. Proteins for SLC26A6 

    Gene Ontology (GO): 5/13 cellular component terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IEA--
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane IEA--
    GO:0012506vesicle membrane ISS--
    GO:0016020membrane ISS--

    SLC26A6 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: PAT-1 
    Chloride/bicarbonate exchangers

    4 InterPro protein domains:
     IPR002645 STAS_dom
     IPR018045 S04_transporter_CS
     IPR001902 SulP_transpt
     IPR011547 Sulph_transpt

    Graphical View of Domain Structure for InterPro Entry Q9BXS9

    ProtoNet protein and cluster: Q9BXS9

    1 Blocks protein domain: IPB001902 Sulphate transporter

    UniProtKB/Swiss-Prot: S26A6_HUMAN, Q9BXS9
    Similarity: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family
    Similarity: Contains 1 STAS domain


    SLC26A6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S26A6_HUMAN, Q9BXS9
    Function: Does not seem to be involved in anion transport

         Gene Ontology (GO): 5/13 molecular function terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005254chloride channel activity IEA--
    GO:0005515protein binding IPI12444019
    GO:0008271secondary active sulfate transmembrane transporter activity IEA--
    GO:0015106bicarbonate transmembrane transporter activity ISS--
    GO:0015108chloride transmembrane transporter activity ISS--
         
    SLC26A6 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for SLC26A6:
     Decreased viability  Synthetic lethal with Ras 

         4 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Slc26a6):
     digestive/alimentary  endocrine/exocrine gland  homeostasis/metabolism  renal/urinary system 

    SLC26A6 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for SLC26A6: Slc26a6tm1Psar Slc26a6tm1Sole Slc26a6tm1Smua

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    SwitchGear 3'UTR luciferase reporter plasmidSLC26A6 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC26A6 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1SLC-mediated transmembrane transport
    SLC-mediated transmembrane transport0.50
    Transmembrane transport of small molecules0.50
    2Amino acid and oligopeptide SLC transporters
    Transport of inorganic cations/anions and amino acids/oligopeptides0.52
    3Multifunctional anion exchangers
    Multifunctional anion exchangers
    4Mineral absorption
    Mineral absorption

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for SLC26A6
        Multifunctional anion exchangers
    SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of inorganic cations/anions and amino acids/oligopeptides


    1         Kegg Pathway  (Kegg details for SLC26A6):
        Mineral absorption


    SLC26A6 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SLC26A6

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for SLC26A6 (Q9BXS93 ENSP000003789204) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PDZK1Q5T2W13, ENSP000003421434I2D: score=1 STRING: ENSP00000342143
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/22 biological process terms (GO ID links to tree view) (see all 22):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport TAS--
    GO:0006821chloride transport IMP--
    GO:0008272sulfate transport ISS--
    GO:0015701bicarbonate transport IMP--
    GO:0015724formate transport ISS--

    SLC26A6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC26A6 (S26A6)

    Search CenterWatch for drugs/clinical trials and news about SLC26A6 / S26A6

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC26A6 gene (6 alternative transcripts): 
    NM_001040454.1  NM_001281732.1  NM_001281733.1  NM_022911.2  NM_134263.2  NM_134426.2  

    Unigene Clusters for SLC26A6:

    Solute carrier family 26, member 6
    Hs.631925  [show with all ESTs], Hs.663208  [show with all ESTs]
    Unigene Representative Sequences: NM_001040454, AF150415
    18/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22):
    ENST00000420764(uc011bbp.2 uc003cuh.3 uc003cui.3) ENST00000489483
    ENST00000395550 ENST00000383733(uc003cuj.3) ENST00000307364(uc010hke.3)
    ENST00000337000(uc003cuk.3) ENST00000480524 ENST00000455886 ENST00000466257
    ENST00000462009 ENST00000469693 ENST00000496469 ENST00000421649 ENST00000444531
    ENST00000414944 ENST00000485361 ENST00000494717 ENST00000482282
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    Additional mRNA sequence: AF161369.1 

    16 DOTS entries:

    DT.114485  DT.100814279  DT.100745852  DT.75102906  DT.302991  DT.99994018  DT.120910990  DT.100649110 
    DT.120911034  DT.92425765  DT.100008831  DT.100024321  DT.100668200  DT.75194168  DT.92425760  DT.305126 

    24/154 AceView cDNA sequences (see all 154):

    NM_134426 CF131391 AB033288 BM668143 BQ951689 BM981593 BE348329 AW206043 
    AA324420 AW779600 BU543732 BU848723 BE217837 BU542954 BM703189 NM_134263 
    BM846802 AF288410 AF279265 BM709189 BM996044 AL050170 BQ681565 AA609061 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC26A6 expression in normal human tissues (normalized intensities)      SLC26A6 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGTCAGGCT
    SLC26A6 Expression
    About this image


    SLC26A6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Gut Tube (Gastrointestinal Tract)
             Definitive endoderm-like cells ( A scalable, suspension protocol for derivation of...
     
     Uterus (Reproductive System)
             endometrial endothelial cell   

    See SLC26A6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC26A6

    SOURCE GeneReport for Unigene clusters: Hs.631925 Hs.663208

    UniProtKB/Swiss-Prot: S26A6_HUMAN, Q9BXS9
    Tissue specificity: Ubiquitous. Highest levels in kidney and pancreas. Lower expression in heart, skeletal muscle,
    liver and placenta. Also found in lung and brain

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC26A6 gene from 9/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc26a61 , 5 solute carrier family 26, member 61, 5 81.13(n)1
    78.94(a)1
      9 (59.63 cM)5
    1714291  NM_134420.41  NP_599252.21 
     1088540375 
    chicken
    (Gallus gallus)
    Aves SLC26A61 solute carrier family 26, member 6 65.85(n)
    61.41(a)
      416012  NM_001252254.1  NP_001239183.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC26A66
    solute carrier family 26, member 6
    55(a)
    1 ↔ 1
    2(164375606-164409228)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.54312 Xenopus laevis transcribed sequence with weak similarity more 73.01(n)    CA792851.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1000051081 novel protein similar to solute carrier family 26, more 57.7(n)
    53.07(a)
      100005108  XM_001344207.3  XP_001344243.3 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0107251 AGAP010725-PA 49.66(n)
    35.91(a)
      1272527  XM_559235.3  XP_559235.3 
    worm
    (Caenorhabditis elegans)
    Secernentea K12G11.23
    sulp-61
    sulphate transporter3
    Protein SULP-61
    35(a)
    (best of 7)3
    45.87(n)1
    32.82(a)1
      V(11882664-11885565)3
    1890851  NM_058737.31  NP_491138.21 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SULTR3;41 putative sulfate transporter 3.4 42.68(n)
    30.31(a)
      820844  NM_112469.2  NP_188220.1 
    rice
    (Oryza sativa)
    Liliopsida Os06g01437001 hypothetical protein 46.3(n)
    32.43(a)
      4340095  NM_001063313.1  NP_001056778.1 


    ENSEMBL Gene Tree for SLC26A6 (if available)
    TreeFam Gene Tree for SLC26A6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC26A6 gene
    SLC26A92  SLC26A32  SLC26A12  SLC26A52  SLC26A112  SLC26A22  SLC26A102  SLC26A72  
    SLC26A42  SLC26A82  
    14 SIMAP similar genes for SLC26A6 using alignment to 12 protein entries:     S26A6_HUMAN (see all proteins):
    DKFZp586E1422    RESDA1    SLC26A11    SLC26A7    SLC26A4    SLC26A10
    SLC26A5    SLC26A2    DKFZp686P10213    PRES    SLC26A3    SLC26A9
    SLC26A8    SLC26A1

    SLC26A6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/307 SNPs in SLC26A6 are shown (see all 307)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1871645971,2
    --48662716(+) TCCACC/TTGCCT 4 -- ds50010--------
    rs1915455991,2
    --48662762(+) CACCGC/TGCCCG 4 -- ds50010--------
    rs1833122911,2
    --48662887(+) CTTCTC/TGGGTA 4 -- ds50010--------
    rs1868461151,2
    --48662888(+) TTCTCA/GGGTAT 4 -- ds50010--------
    rs1403311711,2
    C--48662910(+) AATTAC/TTCCTG 4 -- ds50010--------
    rs76315741,2
    C,F,A,H--48663046(+) GAGTCC/TTTCCT 4 -- ds500124Minor allele frequency- T:0.27NS EA NA WA CSA 2350
    rs1898091701,2
    --48663066(+) GCCCCA/GTCTCA 4 -- ds50010--------
    rs578271371,2
    F--48663128(+) CAGGGA/CCCCAC 4 -- ds50010--------
    rs1820842171,2
    --48663167(+) AGACAA/GATCTT 4 -- ut310--------
    rs1388647521,2
    --48663215(+) GTACCA/GCGCCA 4 -- ut310--------

    HapMap Linkage Disequilibrium report for SLC26A6 (48663156 - 48672926 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for SLC26A6:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2725248CNV Deletion23290073
    nsv876762CNV Loss21882294
    nsv834685CNV Loss17160897
    nsv876763CNV Loss21882294
    nsv523981CNV Loss19592680
    nsv818138CNV Gain17921354


    Human Gene Mutation Database (HGMD): SLC26A6
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC26A6
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC26A6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610068    OMIM disorders: --

    12 diseases for SLC26A6:    About MalaCards
    acute urate nephropathy    fainting    renal tubular acidosis    primary hyperparathyroidism
    primary hyperoxaluria    diastrophic dysplasia    nephrolithiasis    hyperparathyroidism
    cystic fibrosis    schizophrenia    tuberculosis    pancreatitis

    5 diseases from the University of Copenhagen DISEASES database for SLC26A6:
    Primary hyperoxaluria     Nephrolithiasis     Cystic fibrosis     Diastrophic dysplasia
    Acute urate nephropathy

    SLC26A6 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC26A6
    Human Genome Epidemiology (HuGE) Navigator: SLC26A6 (3 documents)

    Export disorders for SLC26A6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC26A6 gene, integrated from 9 sources (see all 36):
    (articles sorted by number of sources associating them with SLC26A6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger. (PubMed id 11087667)1, 2, 3, 9 Lohi H....Kere J. (2000)
    2. Cloning and characterization of SLC26A6, a novel member of the solute carrier 26 gene family. (PubMed id 11247665)1, 2, 3 Waldegger S....Kubisch C. (2001)
    3. Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population. (PubMed id 19367581)1, 4 So H.C....Sham P.C. (2009)
    4. Analysis of the 206M polymorphic variant of the SLC26A6 gene encoding a Cl--oxalate transporter in patients with primary hyperparathyroidism. (PubMed id 19029225)1, 4 Corbetta S....Spada A. (2008)
    5. Phenotypic and functional analysis of human SLC26A6 variants in patients with familial hyperoxaluria and calcium oxalate nephrolithiasis. (PubMed id 18951670)1, 4 Monico C.G....Aronson P.S. (2008)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    9. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 65010 HGNC: 14472 AceView: COL7A1.1 Ensembl:ENSG00000225697 euGenes: HUgn65010
    ECgene: SLC26A6 Kegg: 65010 H-InvDB: SLC26A6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC26A6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC26A6 gene:
    Search GeneIP for patents involving SLC26A6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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