Aliases for SLC26A4 Gene
External Ids for SLC26A4 Gene
Previous HGNC Symbols for SLC26A4 Gene
Previous GeneCards Identifiers for SLC26A4 Gene
Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene; they have similar genomic structures and this gene is located 3' of the SLC26A3 gene. The encoded protein has homology to sulfate transporters. [provided by RefSeq, Jul 2008]
GeneCards Summary for SLC26A4 Gene
SLC26A4 (Solute Carrier Family 26 (Anion Exchanger), Member 4) is a Protein Coding gene. Diseases associated with SLC26A4 include pendred syndrome and deafness, autosomal recessive 4, with enlarged vestibular aqueduct. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Insulin secretion. GO annotations related to this gene include secondary active sulfate transmembrane transporter activity and chloride transmembrane transporter activity. An important paralog of this gene is SLC26A2.
UniProtKB/Swiss-Prot for SLC26A4 Gene
Sodium-independent transporter of chloride and iodide.