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SLC26A11 Gene

protein-coding   GIFtS: 55
GCID: GC17P078194

Solute Carrier Family 26 (Anion Exchanger), Member 11

(Previous names: solute carrier family 26, member 11)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 26 (Anion Exchanger), Member 111 2
Solute Carrier Family 26, Member 111 2
Sodium-Independent Sulfate Anion Transporter2
Solute Carrier Family 26 Member 113

External Ids:    HGNC: 144711   Entrez Gene: 2841292   Ensembl: ENSG000001810457   OMIM: 6101175   UniProtKB: Q86WA93   

Export aliases for SLC26A11 gene to outside databases

Previous GC identifers: GC17U990215 GC17P078757 GC17P078894 GC17P075808 GC17P073635


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC26A11 Gene:
This gene encodes a member of the solute linked carrier 26 family of anion exchangers. Members of this family of
proteins are essential for numerous cellular functions including homeostasis and intracellular electrolyte
balance. The encoded protein is a sodium independent sulfate transporter that is sensitive to the anion exchanger
inhibitor 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid. Alternate splicing results in multiple transcript
variants.(provided by RefSeq, Oct 2009)

GeneCards Summary for SLC26A11 Gene:
SLC26A11 (solute carrier family 26 (anion exchanger), member 11) is a protein-coding gene. GO annotations related to this gene include anion transmembrane transporter activity and secondary active sulfate transmembrane transporter activity. An important paralog of this gene is SLC26A9.

UniProtKB/Swiss-Prot: S2611_HUMAN, Q86WA9
Function: Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to
mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC26A11 gene promoter:
         Lmo2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC26A11 promoter sequence
   Search Chromatin IP Primers for SLC26A11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC26A11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.3   Ensembl cytogenetic band:  17q25.3   HGNC cytogenetic band: 17q25

SLC26A11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC26A11 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P078194:  view genomic region     (about GC identifiers)

Start:
78,193,498 bp from pter      End:
78,227,308 bp from pter
Size:
33,811 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: S2611_HUMAN, Q86WA9 (See protein sequence)
Recommended Name: Sodium-independent sulfate anion transporter  
Size: 606 amino acids; 65299 Da
Secondary accessions: B2RCI7 Q86VX1 Q86YX7 Q8IV11 Q8N2I1 Q8NG03

Explore the universe of human proteins at neXtProt for SLC26A11: NX_Q86WA9

Explore proteomics data for SLC26A11 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys578, Lys600
  • Modification sites at PhosphoSitePlus

  • See SLC26A11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001159819.1  NP_001159820.1  NP_001159821.1  NP_775897.3  

    ENSEMBL proteins: 
     ENSP00000458521   ENSP00000459735   ENSP00000355384   ENSP00000460535   ENSP00000459420  
     ENSP00000403998   ENSP00000440724   ENSP00000459470   ENSP00000458831   ENSP00000458234  
     ENSP00000459379  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: SLC26A11
    Other SLC26 anion exchangers

    3 InterPro protein domains:
     IPR002645 STAS_dom
     IPR018045 S04_transporter_CS
     IPR011547 Sulph_transpt

    Graphical View of Domain Structure for InterPro Entry Q86WA9

    ProtoNet protein and cluster: Q86WA9

    1 Blocks protein domain: IPB001902 Sulphate transporter

    UniProtKB/Swiss-Prot: S2611_HUMAN, Q86WA9
    Similarity: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family
    Similarity: Contains 1 STAS domain


    Find genes that share domains with SLC26A11           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S2611_HUMAN, Q86WA9
    Function: Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to
    mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008271secondary active sulfate transmembrane transporter activity IEA--
    GO:0008509anion transmembrane transporter activity IDA12626430
    GO:0015116sulfate transmembrane transporter activity ----
    GO:0015301anion:anion antiporter activity IEA--
         
    Find genes that share ontologies with SLC26A11           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC26A11:
     Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for Slc26a11 (no phenotypes)

    Find genes that share phenotypes with SLC26A11           About GenesLikeMe

    Animal Models:
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    hsa-miR-520d-5p hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmidSLC26A11 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    S2611_HUMAN, Q86WA9: Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    golgi apparatus5
    lysosome5
    plasma membrane5
    vacuole5

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005765lysosomal membrane IDA--
    GO:0005783endoplasmic reticulum IDA12626430
    GO:0005794Golgi apparatus IDA12626430
    GO:0005886plasma membrane IDA12626430
    GO:0016021integral component of membrane IDA12626430

    Find genes that share ontologies with SLC26A11           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC26A11
    Interactions:

        Search GeneGlobe Interaction Network for SLC26A11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for SLC26A11 (Q86WA93 ENSP000003553844) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SKP1P632083, ENSP000002314874I2D: score=1 STRING: ENSP00000231487
    AK2P548193I2D: score=1 
    CTHP329293I2D: score=1 
    ETF1P624953I2D: score=1 
    FPGSQ059323I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008272sulfate transport IDA12626430

    Find genes that share ontologies with SLC26A11           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC26A11 (S2611)

    2 HMDB Compounds for SLC26A11    About this table
    CompoundSynonyms CAS #PubMed Ids
    SodiumSodium (see all 2)7440-23-5--
    SulfateSulfate (ion 2-) (see all 9)14808-79-8--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SLC26A11 gene (4 alternative transcripts): 
    NM_001166347.1  NM_001166348.1  NM_001166349.1  NM_173626.3  

    Unigene Cluster for SLC26A11:

    Solute carrier family 26, member 11
    Hs.4866  [show with all ESTs]
    Unigene Representative Sequence: NM_001166347
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000577155 ENST00000573809 ENST00000361193(uc002jyb.2 uc002jyc.2 uc002jyd.2)
    ENST00000574967 ENST00000572652 ENST00000576126 ENST00000571888 ENST00000411502
    ENST00000546047(uc010dhv.2) ENST00000571602 ENST00000571564 ENST00000572725
    ENST00000572226 ENST00000571176 ENST00000571072 ENST00000571215 ENST00000575019

    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate SLC26A11:
    hsa-miR-520d-5p hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmidSLC26A11 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat SLC26A11
      QuantiFast Probe-based Assays in human, mouse, rat SLC26A11

    Additional mRNA sequence: 

    AF331524.1 AF345195.1 AJ544073.1 AK027293.1 AK075248.1 AK315132.1 AL833468.1 BC015160.1 
    BC035900.1 BC047451.1 

    11 DOTS entries:

    DT.100027253  DT.444597  DT.97812379  DT.100678883  DT.95152836  DT.100796179  DT.100056599  DT.100796178 
    DT.91977180  DT.95332799  DT.120944802 

    Selected AceView cDNA sequences (see all 129):

    AK075248 BQ671871 BU733297 CB153090 Z41172 NM_173626 CB995731 BU680949 
    BQ682040 AA385773 BQ720290 BQ899095 BQ896674 BQ446507 CO245553 BM695678 
    CB321783 CO394387 CA435887 BM707804 BG742630 BM701149 BM724014 BE502565 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SLC26A11 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b ^
    SP1:              -     -                                         -                       -                 -                                                   
    SP2:                    -     -                                   -                       -                 -                                                   
    SP3:                                                                                      -                                                                     
    SP4:              -     -     -                                                                                                                                 
    SP5:                                                                                                                                                            

    ExUns: 16 ^ 17 ^ 18 ^ 19a · 19b
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:        -                     


    ECgene alternative splicing isoforms for SLC26A11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC26A11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGTCATTTG
    SLC26A11 Expression
    About this image


    SLC26A11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Epithelial Cells
             Mature Choroid Plexus Cells Choroid Plexus
     
     Brain (Nervous System)
             Mature Choroid Plexus Cells Choroid Plexus
     
     Kidney (Urinary System)
             Intercalated Cells Renal Collecting Duct System
    SLC26A11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC26A11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.4866

    UniProtKB/Swiss-Prot: S2611_HUMAN, Q86WA9
    Tissue specificity: Detected in all tissues tested with highest expression observed in brain, kidney, HEVEC and
    placenta and lowest in pancreas, skeletal muscle, liver, lung and heart

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC26A11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC26A11 gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc26a111 , 5 solute carrier family 26, member 111, 5 82.8(n)1
    82.85(a)1
      11 (83.36 cM)5
    2685121  NM_178743.31  NP_848858.21 
     1193555575 
    chicken
    (Gallus gallus)
    Aves SLC26A111 solute carrier family 26, member 11 72.26(n)
    68.25(a)
      768556  XM_001231562.3  XP_001231563.3 
    lizard
    (Anolis carolinensis)
    Reptilia SLC26A116
    solute carrier family 26 (anion exchanger), member...
    70(a)
    1 ↔ 1
    2(100529837-100550811)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia slc26a111 solute carrier family 26, member 11 61.26(n)
    61.83(a)
      100486579  XM_002937308.2  XP_002937354.2 
    zebrafish
    (Danio rerio)
    Actinopterygii wufd14d062 wufd14d06 72.92(n)   327138  BC054629.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG50026
    CG79126
    (see all 8)
    --
    40(a)
    40(a)
    (see all 8)
    1 ↔ many
    1 ↔ many
    (see all 8)
    2R(13637803-13640719)
    3R(25831756-25834911)
    worm
    (Caenorhabditis elegans)
    Secernentea sulp-16
    Protein SULP-1 (sulp-1) mRNA, complete cds
    14(a)
    many ↔ many
    I(6482451-6485857) WBGene00016945
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SUL1(YBR294W)4
    SUL11
    High affinity sulfate permease of the SulP anion transporter more4
    SUL11
    44.18(n)1
    38.21(a)1
      2(789235-791814)4
    8525971, 4  NP_009853.31  NP_009853.14 


    ENSEMBL Gene Tree for SLC26A11 (if available)
    TreeFam Gene Tree for SLC26A11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC26A11 gene
    SLC26A92  SLC26A32  SLC26A62  SLC26A12  SLC26A52  SLC26A22  SLC26A102  SLC26A72  
    SLC26A42  SLC26A82  
    5 SIMAP similar genes for SLC26A11 using alignment to 9 protein entries:     S2611_HUMAN (see all proteins):
    SLC26A6    SLC26A2    SLC26A3    SLC26A4    SLC26A5

    Find genes that share paralogs with SLC26A11           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC26A11 (see all 1050)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1408312411,2
    --78196220(+) GCACAC/TGGGCC 4 -- int10--------
    rs99123601,2
    C,F,A,H--78196228(+) GCCTGC/TACCGA 4 -- int111Minor allele frequency- T:0.48NA WA CSA EA 375
    rs740006341,2
    --78196287(+) AAAAAG/AGTGGC 4 -- int11Minor allele frequency- A:0.50WA 2
    rs1501593151,2
    C--78196319(+) CCCACA/GGGGCA 4 -- int10--------
    rs1386541521,2
    --78196376(+) CATCCC/TGAGCT 4 -- int10--------
    rs1849941961,2
    C--78196444(+) CCTCTC/GTCCCC 4 -- int10--------
    rs1414727061,2
    C,F--78196475(+) CCTTCA/CTGGGC 8 M L mis12Minor allele frequency- C:0.00NA EU 5875
    rs1908980931,2
    C--78196487(+) GCTTCA/GTGTAT 8 M V mis10--------
    rs2022206081,2
    C--78196511(+) CCTCCC/TGGGAT 8 R W mis10--------
    rs1452029861,2
    --78196527(+) CTGGG-/CCCCCCA 8 T P fra10--------

    HapMap Linkage Disequilibrium report for SLC26A11 (78193498 - 78227308 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for SLC26A11:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv457968CNV Loss19166990
    nsv833562CNV Loss17160897
    nsv908982CNV Loss21882294
    dgv3298n71CNV Loss21882294
    dgv3297n71CNV Loss21882294
    nsv469591CNV Loss16826518
    nsv908983CNV Gain21882294
    nsv828123CNV Gain20364138
    nsv908984CNV Gain21882294

    Human Gene Mutation Database (HGMD): SLC26A11
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC26A11
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC26A11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610117    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for SLC26A11:
    Diastrophic dysplasia

    Find genes that share disorders with SLC26A11           About GenesLikeMe

    Genetic Association Database (GAD): SLC26A11

    Export disorders for SLC26A11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC26A11 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with SLC26A11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Molecular and functional characterization of SLC26A11, a sodium- independent sulfate transporter from high endothelial venules. (PubMed id 12626430)1, 2 Vincourt J.-B.... Girard J.-P. (FASEB J. 2003)
    4. PSORS2 is due to mutations in CARD14. (PubMed id 22521418)2 Jordan C.T.... Bowcock A.M. (Am. J. Hum. Genet. 2012)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways. (PubMed id 21752829)1 Palmieri M....Ballabio A. (Hum. Mol. Genet. 2011)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. The proteome of lysosomes. (PubMed id 20957757)2 Schroeder B.A.... Saftig P. (Proteomics 2010)
    10. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 284129 HGNC: 14471 AceView: SLC26A11 Ensembl:ENSG00000181045 euGenes: HUgn284129
    ECgene: SLC26A11 H-InvDB: SLC26A11

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC26A11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC26A11 gene:
    Search GeneIP for patents involving SLC26A11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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