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SLC26A1 Gene

protein-coding   GIFtS: 57
GCID: GC04M000962

Solute Carrier Family 26 (Anion Exchanger), Member 1

(Previous names: solute carrier family 26 (sulfate transporter), member 1)
  See SLC26A1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 26 (Anion Exchanger), Member 11 2     Sulfate Anion Tranporter AT12
SAT12 3 5     Sulfate Anion Transporter 12
Solute Carrier Family 26 (Sulfate Transporter), Member 11 2     Sulfate/Anion Transporter SAT-1 Protein2
SAT-12 3     Solute Carrier Family 26 Member 13
EDM42     SLC25A15

External Ids:    HGNC: 109931   Entrez Gene: 108612   Ensembl: ENSG000001452177   OMIM: 6101305   UniProtKB: Q9H2B43   

Export aliases for SLC26A1 gene to outside databases

Previous GC identifer: GC04M001015


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC26A1 Gene:
This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their
genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different
tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice
variants that encode different isoforms have been identified. (provided by RefSeq, Jul 2008)

GeneCards Summary for SLC26A1 Gene:
SLC26A1 (solute carrier family 26 (anion exchanger), member 1) is a protein-coding gene. Diseases associated with SLC26A1 include mucopolysaccharidoses, and morquio syndrome b. GO annotations related to this gene include secondary active sulfate transmembrane transporter activity and chloride transmembrane transporter activity. An important paralog of this gene is SLC26A9.

UniProtKB/Swiss-Prot: S26A1_HUMAN, Q9H2B4
Function: High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate. Mediates sulfate
and oxalate transport




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NT_006051.19  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC26A1 gene promoter:
         p53   Nkx2-5   CUTL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC26A1 promoter sequence
   Search Chromatin IP Primers for SLC26A1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC26A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16.3   Ensembl cytogenetic band:  4p16.3   HGNC cytogenetic band: 4p16.3

SLC26A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC26A1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M000962:  view genomic region     (about GC identifiers)

Start:
972,861 bp from pter      End:
987,228 bp from pter
Size:
14,368 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: S26A1_HUMAN, Q9H2B4 (See protein sequence)
Recommended Name: Sulfate anion transporter 1  
Size: 701 amino acids; 75016 Da
Secondary accessions: A8K9N2 Q7Z5R3 Q96BK0
Alternative splicing: 2 isoforms:  Q9H2B4-1   Q9H2B4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC26A1: NX_Q9H2B4

Explore proteomics data for SLC26A1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn158, Asn163
  • Modification sites at PhosphoSitePlus

  • See SLC26A1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_071325.2  NP_602297.1  NP_998778.1  

    ENSEMBL proteins: 
     ENSP00000381532   ENSP00000354721   ENSP00000381528  
    Reactome Protein details: Q9H2B4

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Sat-1
    Selective sulphate transporters

    4 InterPro protein domains:
     IPR002645 STAS_dom
     IPR018045 S04_transporter_CS
     IPR001902 SulP_transpt
     IPR011547 Sulph_transpt

    Graphical View of Domain Structure for InterPro Entry Q9H2B4

    ProtoNet protein and cluster: Q9H2B4

    1 Blocks protein domain: IPB001902 Sulphate transporter

    UniProtKB/Swiss-Prot: S26A1_HUMAN, Q9H2B4
    Similarity: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family
    Similarity: Contains 1 STAS domain


    Find genes that share domains with SLC26A1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S26A1_HUMAN, Q9H2B4
    Function: High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate. Mediates sulfate
    and oxalate transport

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008271secondary active sulfate transmembrane transporter activity IEA--
    GO:0015108chloride transmembrane transporter activity ISS--
    GO:0015116sulfate transmembrane transporter activity ISS--
    GO:0015301anion:anion antiporter activity ISS--
    GO:0019531oxalate transmembrane transporter activity ISS--
         
    Find genes that share ontologies with SLC26A1           About GenesLikeMe


    Phenotypes:
         6 MGI mutant phenotypes (inferred from 1 allele(MGI details for Slc26a1):
     cellular  digestive/alimentary  homeostasis/metabolism  immune system  liver/biliary system 
     renal/urinary system 

    Find genes that share phenotypes with SLC26A1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Slc26a1tm1Mark for SLC26A1

       genOway: Develop your customized and physiologically relevant rodent model for SLC26A1

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    S26A1_HUMAN, Q9H2B4: Membrane; Multi-pass membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane4
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016020membrane ----
    GO:0016021integral component of membrane TAS11087667

    Find genes that share ontologies with SLC26A1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SLC26A1 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1MPS VI - Maroteaux-Lamy syndrome
    MPS VI - Maroteaux-Lamy syndrome0.45
    MPS IIIB - Sanfilippo syndrome B0.45
    MPS IIIC - Sanfilippo syndrome C0.45
    MPS II - Hunter syndrome0.45
    MPS IV - Morquio syndrome A0.45
    Glycosaminoglycan metabolism0.45
    Mucopolysaccharidoses0.45
    MPS IV - Morquio syndrome B0.45
    2Biological oxidations
    Biological oxidations0.56
    Cytosolic sulfonation of small molecules0.00
    Phase II conjugation0.56
    Transport and synthesis of PAPS0.00
    3Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    SLC-mediated transmembrane transport0.47
    Transport of inorganic cations/anions and amino acids/oligopeptides0.38
    Transmembrane transport of small molecules0.47
    Multifunctional anion exchangers0.00
    4Metabolism
    Metabolism0.38
    5Disease
    Disease


    Find genes that share SuperPaths with SLC26A1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 Reactome Pathways for SLC26A1
        Multifunctional anion exchangers
    Transport and synthesis of PAPS


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC26A1
    Interactions:

        Search GeneGlobe Interaction Network for SLC26A1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for SLC26A1 (Q9H2B43 ENSP000003547214) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    NDUFAB1ENSP000000075164STRING: ENSP00000007516
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006805xenobiotic metabolic process TAS--
    GO:0006811ion transport TAS--
    GO:0006821chloride transport ISS--
    GO:0008272sulfate transport ISS--

    Find genes that share ontologies with SLC26A1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Compounds for SLC26A1 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    YM 750Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor[138046-43-2]
    VULM 1457Acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor[228544-65-8]
    N1,N11-Diethylnorspermine tetrahydrochloride Spermine and spermidine acetyltransferase potentiator[121749-39-1]
    (R)-(+)-Etomoxir sodium saltCarnitine palmitoyltransferase I (CPT1) inhibitor[828934-41-4]
    A 922500Diacylglycerol acyltransferase 1 (DGAT-1) inhibitor[959122-11-3]

    6 Novoseek inferred chemical compound relationships for SLC26A1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    oxalate 75.7 5 20160351 (2), 15720248 (1), 12605306 (1)
    sulfate 69.1 14 12713736 (2), 20160351 (2), 12605306 (2), 15720248 (1) (see all 6)
    iodide 58.3 1 15720248 (1)
    formate 52.3 1 15720248 (1)
    chloride 46.9 1 15720248 (1)
    bicarbonate 40.1 1 15720248 (1)



    Find genes that share compounds with SLC26A1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SLC26A1 gene (3 alternative transcripts): 
    NM_022042.3  NM_134425.2  NM_213613.3  

    Unigene Cluster for SLC26A1:

    Solute carrier family 26 (sulfate transporter), member 1
    Hs.658244  [show with all ESTs]
    Unigene Representative Sequence: AY124771
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000398520(uc003gbx.3) ENST00000361661(uc003gcb.3 uc003gcc.3)
    ENST00000398516 ENST00000513138
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    Additional mRNA sequence: 

    AF297659.2 AK292747.1 AY124771.1 BC015517.2 

    6 DOTS entries:

    DT.101977060  DT.40188696  DT.91974331  DT.97833470  DT.95211433  DT.100748479 

    16 AceView cDNA sequences:

    NM_134425 NM_022042 AF297659 AY124771 BM855382 NM_213613 BM789616 BC015517 
    AI651437 BF589989 BE787840 BU185680 BQ446374 BI761189 BG910609 R97279 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC26A1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTAGTGGGCC
    SLC26A1 Expression
    About this image


    SLC26A1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Liver (Hepatobiliary System)
             Liver Lobule
    SLC26A1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC26A1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.658244

    UniProtKB/Swiss-Prot: S26A1_HUMAN, Q9H2B4
    Tissue specificity: Expressed most abundantly in the kidney and liver, with lower levels in the pancreas, testis,
    brain, small intestine, colon, and lung

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC26A1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc26a11 , 5 solute carrier family 26 (sulfate transporter), member more1, 5 77.22(n)1
    79.23(a)1
      5 (53.24 cM)5
    2315831  NM_174870.31  NP_777359.31 
     1086698785 
    chicken
    (Gallus gallus)
    Aves SLC26A16
    solute carrier family 26 (anion exchanger), member...
    49(a)
    1 ↔ 1
    Z(53360838-53394897)
    lizard
    (Anolis carolinensis)
    Reptilia SLC26A16
    solute carrier family 26 (anion exchanger), member...
    55(a)
    1 ↔ 1
    GL343201.1(892369-951292)
    zebrafish
    (Danio rerio)
    Actinopterygii slc26a16
    solute carrier family 26 (sulfate transporter), me...
    49(a)
    1 ↔ 1
    21(19152437-19156250) ENSDARG00000029832
    fruit fly
    (Drosophila melanogaster)
    Insecta CG54853 high affinity sulfate permease 30(a)   75A9   --
    worm
    (Caenorhabditis elegans)
    Secernentea W04G3.63
    sulp-21
    dra like protein3
    sulp-21
    33(a)
    (best of 6)3
    40.08(n)1
    30.1(a)1
      X(11115908-11117663)3
    1808281  NM_076543.41  NP_508944.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SUL16
    SUL26
    High affinity sulfate permease of the SulP anion t...
    High affinity sulfate permease; sulfate uptake is ...
    16(a)
    16(a)
    many ↔ many
    many ↔ many
    II(789235-791814) YBR294W
    XII(323544-326225) YLR092W


    ENSEMBL Gene Tree for SLC26A1 (if available)
    TreeFam Gene Tree for SLC26A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC26A1 gene
    SLC26A92  SLC26A32  SLC26A62  SLC26A52  SLC26A112  SLC26A22  SLC26A102  SLC26A72  
    SLC26A42  SLC26A82  
    12 SIMAP similar genes for SLC26A1 using alignment to 2 protein entries:     S26A1_HUMAN (see all proteins):
    SLC26A2    DKFZp686P10213    SLC26A5    PRES    SLC26A10    SLC26A4
    GPAT2    LOC150763    SLC26A3    RESDA1    SLC26A6    SLC26A9

    Find genes that share paralogs with SLC26A1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC26A1 (see all 121)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1844054541,2
    --960254(+) GAGGCC/TGAGGC 1 -- ds50010--------
    rs1891615811,2
    --960368(+) CTGTAA/GTCCCA 1 -- ds50010--------
    rs100143181,2
    C--960627(+) aacagC/Tttgct 1 -- ds50010--------
    rs1842115311,2
    --960637(+) TAGGAC/TACCCT 1 -- ds50010--------
    rs1497906741,2
    C--960682(+) TTGCAA/GTATCA 1 -- ut310--------
    rs1894313651,2
    --960770(+) GCTTTA/TCAGAA 1 -- ut310--------
    rs779794461,2
    C,F--960777(+) AGAAAT/CGTACT 1 -- ut311Minor allele frequency- C:0.04WA 118
    rs45837051,2
    C,F,H--960850(+) GGCTTC/TTCTCC 1 -- ut3126Minor allele frequency- T:0.10NA NS EA CSA WA 2906
    rs1810785891,2
    C--960872(+) GCCAGA/GTTGAG 1 -- ut310--------
    rs100056911,2
    C,F,H--960939(+) CCACCG/AGCTTC 1 -- ut314Minor allele frequency- A:0.00NS EA 418

    HapMap Linkage Disequilibrium report for SLC26A1 (972861 - 987228 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SLC26A1 (see all 16):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv5397n71CNV Loss21882294
    nsv4196CNV Loss18451855
    dgv5396n71CNV Loss21882294
    nsv469998CNV Loss18288195
    dgv5390n71CNV Loss21882294
    nsv878292CNV Loss21882294
    nsv822425CNV Loss20364138
    nsv878315CNV Loss21882294
    nsv878287CNV Loss21882294
    nsv878310CNV Loss21882294

    Human Gene Mutation Database (HGMD): SLC26A1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC26A1
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC26A1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610130    OMIM disorders: --

    5 diseases for SLC26A1:    
    About MalaCards
    mucopolysaccharidoses    morquio syndrome b    sly syndrome    renal tubular acidosis
    primary hyperoxaluria

    2 diseases from the University of Copenhagen DISEASES database for SLC26A1:
    Primary hyperoxaluria     Nephrolithiasis

    Find genes that share disorders with SLC26A1           About GenesLikeMe


    Export disorders for SLC26A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC26A1 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with SLC26A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the human sulfate anion transporter (hsat-1) protein and gene (SAT1; SLC26A1). (PubMed id 12713736)1, 2, 9 Regeer R.R.... Markovich D. (DNA Cell Biol. 2003)
    2. Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger. (PubMed id 11087667)1, 2 Lohi H....Kere J. (Genomics 2000)
    3. Glyoxylate is a substrate of the sulfate-oxalate exchanger, sat-1, and increases its expression in HepG2 cells. (PubMed id 21093948)1 Schnedler N....Burckhardt B.C. (J. Hepatol. 2011)
    4. TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells. (PubMed id 19850743)1 Vanderwerf S.M....Bagby G.C. (Blood 2009)
    5. Familial pure proximal renal tubular acidosis--a clinical and genetic study. (PubMed id 17881426)1 Katzir Z....Holtzman E. (Nephrol. Dial. Transplant. 2008)
    6. Evaluation of SAT-1, SAT-2 and GalNAcT-1 mRNA in colon cancer by real-time PCR. (PubMed id 17119850)1 Gornati R....Bernardini G. (Mol. Cell. Biochem. 2007)
    7. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10861 HGNC: 10993 AceView: SLC26A1 Ensembl:ENSG00000145217 euGenes: HUgn10861
    ECgene: SLC26A1 H-InvDB: SLC26A1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC26A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC26A1 gene:
    Search GeneIP for patents involving SLC26A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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