Aliases for SLC26A1 Gene
External Ids for SLC26A1 Gene
Previous GeneCards Identifiers for SLC26A1 Gene
This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice variants that encode different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for SLC26A1 Gene
SLC26A1 (Solute Carrier Family 26 (Anion Exchanger), Member 1) is a Protein Coding gene. Diseases associated with SLC26A1 include diastrophic dysplasia and atelosteogenesis ii. Among its related pathways are Metabolism and Glycosaminoglycan metabolism. GO annotations related to this gene include secondary active sulfate transmembrane transporter activity and anion:anion antiporter activity. An important paralog of this gene is SLC26A2.
UniProtKB/Swiss-Prot for SLC26A1 Gene
High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate. Mediates sulfate and oxalate transport.