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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC26A1 Gene

protein-coding   GIFtS: 56
GCID: GC04M000962

Solute Carrier Family 26 (Anion Exchanger), Member 1

(Previous names: solute carrier family 26 (sulfate transporter), member 1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 26 (Anion Exchanger), Member 11 2     Sulfate Anion Tranporter AT12
Solute Carrier Family 26 (Sulfate Transporter), Member 11 2     Sulfate Anion Transporter 12
SAT-12 3     Sulfate/Anion Transporter SAT-1 Protein2
SAT12 3     Solute Carrier Family 26 Member 13
EDM42     

External Ids:    HGNC: 109931   Entrez Gene: 108612   Ensembl: ENSG000001452177   OMIM: 6101305   UniProtKB: Q9H2B43   

Export aliases for SLC26A1 gene to outside databases

Previous GC identifer: GC04M001015


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC26A1 Gene:
This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their
genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different
tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice
variants that encode different isoforms have been identified. (provided by RefSeq, Jul 2008)

GeneCards Summary for SLC26A1 Gene: 
SLC26A1 (solute carrier family 26 (anion exchanger), member 1) is a protein-coding gene. Diseases associated with SLC26A1 include fainting, and atelosteogenesis, and among its related super-pathways are Metabolism of carbohydrates and Phase II conjugation. GO annotations related to this gene include secondary active sulfate transmembrane transporter activity and chloride transmembrane transporter activity. An important paralog of this gene is SLC26A9.

UniProtKB/Swiss-Prot: S26A1_HUMAN, Q9H2B4
Function: High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_037622.5  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC26A1 gene promoter:
         p53   Nkx2-5   CUTL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC26A1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC26A1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC26A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16.3   Ensembl cytogenetic band:  4p16.3   HGNC cytogenetic band: 4p16.3

SLC26A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC26A1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M000962:  view genomic region     (about GC identifiers)

Start:
972,861 bp from pter      End:
987,228 bp from pter
Size:
14,368 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: S26A1_HUMAN, Q9H2B4 (See protein sequence)
Recommended Name: Sulfate anion transporter 1  
Size: 701 amino acids; 75016 Da
Subcellular location: Membrane; Multi-pass membrane protein (By similarity)
Secondary accessions: A8K9N2 Q7Z5R3 Q96BK0
Alternative splicing: 2 isoforms:  Q9H2B4-1   Q9H2B4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC26A1: NX_Q9H2B4

Explore proteomics data for SLC26A1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H2B4

  • SLC26A1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC26A1 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_071325.2  NP_602297.1  NP_998778.1  

    ENSEMBL proteins: 
     ENSP00000381532   ENSP00000354721   ENSP00000381528  
    Reactome Protein details: Q9H2B4
    Human Recombinant Protein Products for SLC26A1: 
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    Cloud-Clone Corp. Proteins for SLC26A1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016020membrane ----
    GO:0016021integral to membrane TAS11087667

    SLC26A1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Sat-1 
    Selective sulphate transporters

    4 InterPro protein domains:
     IPR002645 STAS_dom
     IPR018045 S04_transporter_CS
     IPR001902 SulP_transpt
     IPR011547 Sulph_transpt

    Graphical View of Domain Structure for InterPro Entry Q9H2B4

    ProtoNet protein and cluster: Q9H2B4

    1 Blocks protein domain: IPB001902 Sulphate transporter

    UniProtKB/Swiss-Prot: S26A1_HUMAN, Q9H2B4
    Similarity: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family
    Similarity: Contains 1 STAS domain


    SLC26A1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S26A1_HUMAN, Q9H2B4
    Function: High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008271secondary active sulfate transmembrane transporter activity IEA--
    GO:0015108chloride transmembrane transporter activity ISS--
    GO:0015116sulfate transmembrane transporter activity NAS--
    GO:0015301anion:anion antiporter activity ISS--
    GO:0019531oxalate transmembrane transporter activity ISS--
         
    SLC26A1 for ontologies           About GeneDecksing


    Phenotypes:
         6 MGI mutant phenotypes (inferred from 1 allele(MGI details for Slc26a1):
     cellular  digestive/alimentary  homeostasis/metabolism  immune system  liver/biliary system 
     renal/urinary system 

    SLC26A1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Slc26a1tm1Mark for SLC26A1

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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC26A1 About   (see all 8)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1MPS IIIC - Sanfilippo syndrome C
    MPS IIIC - Sanfilippo syndrome C0.48
    Mucopolysaccharidoses0.48
    MPS IV - Morquio syndrome A0.48
    MPS IIID - Sanfilippo syndrome D0.48
    MPS IV - Morquio syndrome B0.48
    MPS I - Hurler syndrome0.48
    MPS VI - Maroteaux-Lamy syndrome0.48
    MPS IX - Natowicz syndrome0.48
    2Biological oxidations
    Biological oxidations0.55
    Phase II conjugation0.55
    3Cytosolic sulfonation of small molecules
    Cytosolic sulfonation of small molecules0.52
    Transport and synthesis of PAPS0.35
    4SLC-mediated transmembrane transport
    SLC-mediated transmembrane transport0.50
    Transmembrane transport of small molecules0.50
    5Amino acid and oligopeptide SLC transporters
    Transport of inorganic cations/anions and amino acids/oligopeptides0.52

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/24        Reactome Pathways for SLC26A1 (see all 24)
        MPS VI - Maroteaux-Lamy syndrome
    Metabolism
    Disease
    Multifunctional anion exchangers
    Transmembrane transport of small molecules



    SLC26A1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC26A1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for SLC26A1 (Q9H2B43 ENSP000003547214) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006805xenobiotic metabolic process TAS--
    GO:0006811ion transport TAS--
    GO:0006821chloride transport ISS--
    GO:0008272sulfate transport NAS--

    SLC26A1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC26A1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for SLC26A1 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    YM 750Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor[138046-43-2]
    VULM 1457Acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor[228544-65-8]
    N1,N11-Diethylnorspermine tetrahydrochloride Spermine and spermidine acetyltransferase potentiator[121749-39-1]
    (R)-(+)-Etomoxir sodium saltCarnitine palmitoyltransferase I (CPT1) inhibitor[828934-41-4]
    A 922500Diacylglycerol acyltransferase 1 (DGAT-1) inhibitor[959122-11-3]

    6 Novoseek inferred chemical compound relationships for SLC26A1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    oxalate 75.7 5 20160351 (2), 15720248 (1), 12605306 (1)
    sulfate 69.1 14 12713736 (2), 20160351 (2), 12605306 (2), 15720248 (1) (see all 6)
    iodide 58.3 1 15720248 (1)
    formate 52.3 1 15720248 (1)
    chloride 46.9 1 15720248 (1)
    bicarbonate 40.1 1 15720248 (1)

    Search CenterWatch for drugs/clinical trials and news about SLC26A1 / S26A1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC26A1 gene (3 alternative transcripts): 
    NM_022042.3  NM_134425.2  NM_213613.3  

    Unigene Cluster for SLC26A1:

    Solute carrier family 26 (sulfate transporter), member 1
    Hs.658244  [show with all ESTs]
    Unigene Representative Sequence: AY124771
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000398520(uc003gbx.3) ENST00000361661(uc003gcb.3 uc003gcc.3)
    ENST00000398516 ENST00000513138
    miRNA
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    Additional mRNA sequence: 

    AF297659.2 AK292747.1 AY124771.1 BC015517.2 

    6 DOTS entries:

    DT.101977060  DT.40188696  DT.91974331  DT.97833470  DT.95211433  DT.100748479 

    16 AceView cDNA sequences:

    AY124771 AF297659 NM_213613 BM855382 NM_022042 BC015517 BM789616 NM_134425 
    AI651437 BF589989 BE787840 BQ446374 BU185680 R97279 BG910609 BI761189 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC26A1 expression in normal human tissues (normalized intensities)      SLC26A1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTAGTGGGCC
    SLC26A1 Expression
    About this image


    SLC26A1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Nose (Sensory Organs)    fully expand to see all 2 entries
             sensory organ/nose/nasal cavity   
     
     Liver (Hepatobiliary System)
             Liver Lobule
     
     Hair (Integumentary System)
             mouse/organ system/integumental system   
     
     Tooth
             mouse/organ system/integumental system   

    See SLC26A1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC26A1

    SOURCE GeneReport for Unigene cluster: Hs.658244

    UniProtKB/Swiss-Prot: S26A1_HUMAN, Q9H2B4
    Tissue specificity: Expressed most abundantly in the kidney and liver, with lower levels in the pancreas, testis,
    brain, small intestine, colon, and lung

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC26A1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC26A1 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc26a11 , 5 solute carrier family 26 (sulfate transporter), member more1, 5 77.22(n)1
    79.23(a)1
      5 (53.24 cM)5
    2315831  NM_174870.31  NP_777359.31 
     1086698785 
    chicken
    (Gallus gallus)
    Aves SLC26A16
    --
    --
    49(a)
    43(a)
    1 ↔ 1
    possible ortholog
    Z(53360838-53394897)
    13(7665423-7670034)
    lizard
    (Anolis carolinensis)
    Reptilia SLC26A16
    solute carrier family 26 (sulfate transporter), me...
    55(a)
    1 ↔ 1
    GL343201.1(892369-951292)
    zebrafish
    (Danio rerio)
    Actinopterygii slc26a11 solute carrier family 26 (sulfate transporter), member more 55.01(n)
    51.35(a)
      791185  NM_001080667.1  NP_001074136.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG54853 high affinity sulfate permease 30(a)   75A9   --
    worm
    (Caenorhabditis elegans)
    Secernentea W04G3.63
    sulp-21
    dra like protein3
    Protein SULP-21
    33(a)
    (best of 6)3
    39.98(n)1
    30.66(a)1
      X(11115908-11117663)3
    1808281  NM_076543.31  NP_508944.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SUL16
    SUL26
    High affinity sulfate permease of the SulP anion t...
    High affinity sulfate permease; sulfate uptake is ...
    17(a)
    15(a)
    many ↔ many
    many ↔ many
    II(789235-791814)
    XII(323544-326225)


    ENSEMBL Gene Tree for SLC26A1 (if available)
    TreeFam Gene Tree for SLC26A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC26A1 gene
    SLC26A92  SLC26A32  SLC26A62  SLC26A52  SLC26A112  SLC26A22  SLC26A102  SLC26A72  
    SLC26A42  SLC26A82  
    12 SIMAP similar genes for SLC26A1 using alignment to 2 protein entries:     S26A1_HUMAN (see all proteins):
    SLC26A2    DKFZp686P10213    SLC26A5    PRES    SLC26A10    SLC26A4
    GPAT2    LOC150763    SLC26A3    RESDA1    SLC26A6    SLC26A9

    SLC26A1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/121 SNPs in SLC26A1 are shown (see all 121)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0467274
    ----see VAR_0467272 Q R mis40--------
    rs1844054541,2
    --960254(+) GAGGCC/TGAGGC 1 -- ds50010--------
    rs1891615811,2
    --960368(+) CTGTAA/GTCCCA 1 -- ds50010--------
    rs100143181,2
    C--960627(+) aacagC/Tttgct 1 -- ds50010--------
    rs1842115311,2
    --960637(+) TAGGAC/TACCCT 1 -- ds50010--------
    rs1497906741,2
    C--960682(+) TTGCAA/GTATCA 1 -- ut310--------
    rs1894313651,2
    --960770(+) GCTTTA/TCAGAA 1 -- ut310--------
    rs779794461,2
    C,F--960777(+) AGAAAT/CGTACT 1 -- ut311Minor allele frequency- C:0.04WA 118
    rs45837051,2
    C,F,H--960850(+) GGCTTC/TTCTCC 1 -- ut3126Minor allele frequency- T:0.10NA NS EA CSA WA 2906
    rs1810785891,2
    C--960872(+) GCCAGA/GTTGAG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SLC26A1 (972861 - 987228 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/16 variations for SLC26A1 (see all 16):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv5397n71CNV Loss21882294
    nsv4196CNV Loss18451855
    dgv5396n71CNV Loss21882294
    nsv469998CNV Loss18288195
    dgv5390n71CNV Loss21882294
    nsv878292CNV Loss21882294
    nsv822425CNV Loss20364138
    nsv878315CNV Loss21882294
    nsv878287CNV Loss21882294
    nsv878310CNV Loss21882294


    Human Gene Mutation Database (HGMD): SLC26A1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC26A1
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC26A1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610130    OMIM disorders: --

    14 diseases for SLC26A1:    About MalaCards
    fainting    atelosteogenesis    primary hyperoxaluria    renal tubular acidosis
    achondrogenesis    diastrophic dysplasia    multiple epiphyseal dysplasia    nephrocalcinosis
    nephrolithiasis    fanconi's anemia    tuberculosis    anemia
    colon cancer    pancreatitis

    2 diseases from the University of Copenhagen DISEASES database for SLC26A1:
    Primary hyperoxaluria     Nephrolithiasis

    SLC26A1 for disorders           About GeneDecksing


    Export disorders for SLC26A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC26A1 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with SLC26A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the human sulfate anion transporter (hsat-1) protein and gene (SAT1; SLC26A1). (PubMed id 12713736)1, 2, 9 Regeer R.R.... Markovich D. (2003)
    2. Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger. (PubMed id 11087667)1, 2 Lohi H....Kere J. (2000)
    3. Glyoxylate is a substrate of the sulfate-oxalate exch anger, sat-1, and increases its expression in HepG2 cells. (PubMed id 21093948)1 Schnedler N....Burckhardt B.C. (2011)
    4. TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells. (PubMed id 19850743)1 Vanderwerf S.M....Bagby G.C. (2009)
    5. Familial pure proximal renal tubular acidosis--a clinical and genetic study. (PubMed id 17881426)1 Katzir Z....Holtzman E. (2008)
    6. Evaluation of SAT-1, SAT-2 and GalNAcT-1 mRNA in colon cancer by real-time PCR. (PubMed id 17119850)1 Gornati R....Bernardini G. (2007)
    7. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10861 HGNC: 10993 AceView: SLC26A1 Ensembl:ENSG00000145217 euGenes: HUgn10861
    ECgene: SLC26A1 H-InvDB: SLC26A1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC26A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC26A1 gene:
    Search GeneIP for patents involving SLC26A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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