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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC25A6 Gene

protein-coding   GIFtS: 59
GCID: GC0XM001505

solute carrier family 25 (mitochondrial carrier; adenine...


(Previous symbol: ANT3)
 Explore 13 diseases affiliated with
SLC25A6 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC25A6    

Aliases
for SLC25A6 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 25 (Mitochondrial Carrier; Adenine Nucleotide
Translocator), Member 61 2
     MGC175251
ANT31 2 3 5     AAC32
ANT3Y1 2     ADP,ATP Carrier Protein2
Adenine Nucleotide Translocator 32 3     ADP,ATP Carrier Protein, Liver2
Solute Carrier Family 25 Member 62 3     ADP/ATP Translocase 32
ADP,ATP Carrier Protein 32 3     ADP/ATP Translocator Of Liver2
ANT 22 3     ADP,ATP Carrier Protein, Isoform T23
ANT 32 3     

External Ids:    HGNC: 109921   Entrez Gene: 2932   Ensembl: ENSG000001691007   OMIM: 3001515   UniProtKB: P122363   

Export aliases for SLC25A6 gene to outside databases

Previous GC identifers: GC0XM000980 GC0XM000821 GC0XM001081 GC0XM001150 GC0YM001548 GC0XM001548 GC0XM001465


Summaries
for SLC25A6 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SLC25A6:
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene
functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is
implicated in the function of the permability transition pore complex (PTPC), which regulates the release of
mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this
gene. (provided by RefSeq, Sep 2009)

UniProtKB/Swiss-Prot: ADT3_HUMAN, P12236
Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May
participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of
mitochondrial products that triggers apoptosis

Gene Wiki entry for SLC25A6


Genomic Views
for SLC25A6 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_000024.9  NC_018934.1  NT_167196.1  NT_167204.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC25A6 gene promoter:
         PPAR-gamma1   Pax-5   GCNF-1   GCNF   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC25A6 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC25A6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC25A6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp22.32 and Yp11.3   Ensembl cytogenetic band:  Xp22.33   HGNC cytogenetic band: Xp22.32 and Yp11.3

SLC25A6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A6 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM001505:  view genomic region     (about GC identifiers)

Start:
 1,505,045 bp from pter      End:
 1,511,626 bp from pter
Size:
 6,582 bases      Orientation:
 minus strand

1 alternative location:
ChrY- 1,455,045-1,461,039     

Proteins
for SLC25A6 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ADT3_HUMAN, P12236 (See protein sequence)
Recommended Name: ADP/ATP translocase 3  
Size: 298 amino acids; 32866 Da
Subunit: Found in a complex with ARL2, ARL2BP and SLC25A6 (By similarity). Homodimer. Interacts with influenza A virus
PB1-F2 protein and HIV-1 Vpr
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein. Note=The complex formed with ARL2BP,
ARL2 and SLC25A6 is expressed in mitochondria (By similarity)
Miscellaneous: The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at
an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue
(By similarity)
Miscellaneous: The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y
chromosomes
Secondary accessions: Q96C49

Explore the universe of human proteins at neXtProt for SLC25A6: NX_P12236

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P12236

    • SLC25A6 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001627.2  
    ENSEMBL proteins: 
     ENSP00000370808   ENSP00000404548  
    Reactome Protein details: P12236
    Human Recombinant Protein Products: 
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    Uscn Proteins for SLC25A6

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005744mitochondrial inner membrane presequence translocase complex TAS2541251
    GO:0016021integral to membrane IEA--


    SLC25A6 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SLC25A6

    Protein Domains /
    Families
    for SLC25A6 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC25A6 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR002067 Mit_carrier
     IPR023395 Mt_carrier_dom
     IPR018108 Mitochondrial_sb/sol_carrier
     IPR002113 Aden_trnslctor

    Graphical View of Domain Structure for InterPro Entry P12236

    ProtoNet protein and cluster: P12236

    2 Blocks protein families:
    IPB002067 Mitochondrial carrier protein signature
    IPB002113 Adenine nucleotide translocator 1 signature


    UniProtKB/Swiss-Prot: ADT3_HUMAN, P12236
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 3 Solcar repeats


    Function
    for SLC25A6 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ADT3_HUMAN, P12236
    Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May
    participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of
    mitochondrial products that triggers apoptosis

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: SLC25A6 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005471ATP:ADP antiporter activity NAS2541251


    SLC25A6 for ontologies           About GeneDecksing



    Pathways & Interactions
    for SLC25A6 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/15 super-pathways (see all 15) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    		Electron Transport Chain0.76
    		Huntington's disease0.40
    		Parkinson's disease0.61
    2HIV Infection
    		HIV Infection1.00
    		Host Interactions of HIV factors0.64
    3Regulation of Insulin Secretion
    		Regulation of Insulin Secretion1.00
    		Integration of energy metabolism0.74
    4Apoptotic Pathways in Synovial Fibroblasts
    		Mitochondrial Apoptosis0.73
    		Cellular Apoptosis Pathway0.65
    5 NS1 Mediated Effects on Host Pathways
    		Host Interactions with Influenza Factors0.60
    		Influenza Virus Induced Apoptosis0.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for SLC25A6
        Apoptosis and survival Regulation of Apoptosis by Mitochondrial Proteins

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for SLC25A6
        Mitochondrial Apoptosis
    Cellular Apoptosis Pathway

    1 GeneGo (Thomson Reuters) Pathway for SLC25A6
        Apoptosis and survival Regulation of Apoptosis by Mitochondrial Proteins

    1 BioSystems Pathway for SLC25A6 
        Electron Transport Chain

    5/13        Reactome Pathways for SLC25A6 (see all 13)
        Metabolism
    Influenza Infection
    Interactions of Vpr with host cellular proteins
    Regulation of Insulin Secretion
    Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization


    4         Kegg Pathways  (Kegg details for SLC25A6):
        Calcium signaling pathway
    Parkinson's disease
    Huntington's disease
    Influenza A


    SLC25A6 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SLC25A6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/330 Interacting proteins for SLC25A6 (P122362, 3 ENSP000003708084) via UniProtKB, MINT, STRING, and/or I2D (see all 330)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EEF1A1P681042, 3MINT-6489217 MINT-6488488 MINT-6489355 I2D: score=1 
    TNFRSF1AP194382, 3, ENSP000001627494MINT-49357 I2D: score=2 STRING: ENSP00000162749
    PLCG1P191742, 3, ENSP000002440074MINT-8112375 I2D: score=1 STRING: ENSP00000244007
    IKBKGQ9Y6K92, 3MINT-48221 I2D: score=2 
    MAP3K1Q132332, 3MINT-48340 I2D: score=2 
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006112energy reserve metabolic process TAS--
    GO:0006626protein targeting to mitochondrion TAS--
    GO:0006915apoptotic process IEA--
    GO:0016032viral reproduction TAS--
    GO:0019048virus-host interaction TAS--


    SLC25A6 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC25A6 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC25A6 for compounds           About GeneDecksing

    EMD Millipore small molecules for SLC25A6:
    Small Molecule - inhibitor
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC25A6

    1 DrugBank Compound for SLC25A6    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Clodronate-- 10596-23-3targetinhibitor11961144

    3 Novoseek chemical compound relationships for SLC25A6 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adp 67.7 4 8486369 (2), 14746803 (1), 16341775 (1)
    atp 55.3 5 8486369 (2), 14746803 (1), 15691486 (1), 16341775 (1)
    cyclosporin a 19.7 1 15063741 (1)

    Search CenterWatch for drugs/clinical trials and news about SLC25A6 / ADT3 

    Transcripts
    for SLC25A6 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC25A6 gene: 
    NM_001636.3  

    Unigene Cluster for SLC25A6:

    Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
    Hs.350927  [show with all ESTs]
    Unigene Representative Sequence: BM455431
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381401(uc004cpt.3) ENST00000475167 ENST00000484026 ENST00000447786


    miRNA
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    hsa-miR-19b hsa-miR-19a
    SwitchGear 3'UTR luciferase reporter plasmid: SLC25A6 3' UTR sequence
    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AB209822.1 AF076617.1 AF091236.1 AK312336.1 AY007135.1 BC007295.1 BC007850.2 BC008737.2 
    BC008935.2 BC013256.1 BC014775.1 BC031912.1 BC035469.1 CR457400.1 J03592.1 

    24/131 DOTS entries (see all 131):

    DT.100714212  DT.100714208  DT.91781059  DT.92037182  DT.455610  DT.100045561  DT.100637571  DT.40115510 
    DT.95263300  DT.91964557  DT.91950160  DT.102838867  DT.91649919  DT.100714176  DT.95263326  DT.100714187 
    DT.120653002  DT.120652842  DT.100714190  DT.100714183  DT.100771650  DT.120652966  DT.121315058  DT.95333723 

    24/2209 AceView cDNA sequences (see all 2209):

    BQ923290 BU507316 CA449188 AA360716 CR608211 BM480028 BE620448 BM562956 
    BM554606 BG258800 BU176934 CR596158 CR605865 T32901 BQ433035 CR595090 
    AU132565 BQ653419 CR626642 BC013256 BU164311 BF915648 BM873389 AA147063 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A6 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5a · 5b ^ 6a · 6b
    SP1:                    -     -     -     -                                   -     -                     
    SP2:                    -           -     -                                                               
    SP3:                    -           -     -                                                               
    SP4:                    -                 -                                                               
    SP5:                    -                 -                                                               


    ECgene alternative splicing isoforms for SLC25A6

    Expression
    for SLC25A6 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC25A6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGTGAGACAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See SLC25A6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC25A6

    SOURCE GeneReport for Unigene cluster: Hs.350927
        SABiosciences Custom PCR Arrays for SLC25A6
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    In Situ
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    Orthologs
    for SLC25A6 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC25A6 gene from 7/23 species (see all 23)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SLC25A61 solute carrier family 25 (mitochondrial carrier; adenine more 79.19(n)
    93.29(a)    		   374072  NM_204231.2  NP_989562.2 
    lizard
    (Anolis carolinensis)    		 Reptilia SLC25A56
    		 --
    		 88(a)
    		 1 ↔ 1
    		 GL344275.1(40640-53099)
    zebrafish
    (Danio rerio)    		 Actinopterygii slc25a61 solute carrier family 25 (mitochondrial carrier; adenine more 77.07(n)
    91.95(a)    		   566370  NM_001128732.1  NP_001122204.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta sesB3
    Ant21    		 carrier3
    Adenine nucleotide translocase 21    		 79(a)
    (best of 2)3
    71.51(n)1
    75.09(a)1    		   320081  NM_078555.31  NP_511110.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea K01H12.23
    ant-1.31    		 ADP/ATP carrier protein3
    Protein ANT-1.31    		 70(a)
    (best of 6)3
    66.55(n)1
    71.87(a)1    		   IV(9708187-9709272)3
    1868551  NM_069326.21  NP_501727.11 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT5G564501 solute carrier family 25 protein 51.62(n)
    47.92(a)    		   835746  NM_125028.1  NP_200456.1 
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 4)    		 mitochondrial carrier protein, putative, expressed...
    mitochondrial carrier protein, putative, expressed...
    (see all 4)    		 42(a)
    40(a)
    (see all 4)    		 possible ortholog
    1 ↔ many
    (see all 4)    		 11(26078289-26080885)
    5(26743216-26747137)


    ENSEMBL Gene Tree for SLC25A6 (if available)
    TreeFam Gene Tree for SLC25A6 (if available) 

    Paralogs
    for SLC25A6 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC25A6 gene
    SLC25A312  SLC25A42  SLC25A52  
    8 SIMAP similar genes for SLC25A6 using alignment to 3 protein entries:     ADT3_HUMAN (see all proteins):
    SLC25A5    SLC25A4    SLC25A31    SLC25A23    SLC25A24    SLC25A42
    SLC25A25    SLC25A12

    SLC25A6 for paralogs           About GeneDecksing


    5/9 Pseudogenes.org Pseudogenes for SLC25A6 (see all 9)
    PGOHUM00000235103 PGOHUM00000244716 PGOHUM00000247463 PGOHUM00000240084 PGOHUM00000243242


    Genomic Variants
    for SLC25A6 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for SLC25A6
         1 CNV: 73906
    Locus Specific Mutation Databases (LSDB): SLC25A6
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC25A6
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC25A6

    Disorders / Diseases
    for SLC25A6 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC25A6 for disorders           About GeneDecksing

    OMIM gene information: 300151    OMIM disorders: --

    13 diseases for SLC25A6:    About MalaCards
    autosomal dominant progressive external ophthalmoplegia    x inactivation    ophthalmoplegia    intrahepatic cholangiocarcinoma
    huntington's disease    cholangiocarcinoma    parkinson's disease    hepatocellular carcinoma
    influenza    prostate cancer    prostatitis    carcinoma
    malaria


    Export disorders for SLC25A6 gene to outside databases

    Publications
    for SLC25A6 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC25A6 gene, integrated from 9 sources (see all 64):
    (articles sorted by number of sources associating them with SLC25A6)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1. (PubMed id 16201016)1, 2 Zamarin D.... Palese P. (2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Mitochondrial membrane permeabilization by HIV-1 Vpr. (PubMed id 16120388)1, 2 Deniaud A.... Kroemer G. (2004)
    4. Study of PTPC composition during apoptosis for identification of viral protein target. (PubMed id 15033708)1, 2 Verrier F.... Brenner C. (2003)
    5. DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase. (PubMed id 2541251)1, 2 Cozens A.L.... Walker J.E. (1989)
    6. Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver. (PubMed id 2829183)1, 2 Houldsworth J. and Attardi G. (1988)
    7. Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells. (PubMed id 15063741)1, 9 Zamora M....Vinas O. (2004)
    8. Mitochondrial adenine nucleotide translocator 3 is regulated by IL-4 and IFN-gamma via STAT-dependent pathways. (PubMed id 14746803)1, 9 Jang J.Y. and Lee C.E. (2003)
    9. IL-4-induced upregulation of adenine nucleotide translocase 3 and its role in Th cell survival from apoptosis. (PubMed id 16930576)1, 9 Jang J.Y. and Lee C.E. (2006)
    10. Molecular interactions between mitochondrial membrane proteins and the C-terminal domain of PB1-F2: an in silico approach. (PubMed id 19669810)1, 9 Danishuddin M....Khan A.U. (2010)

    External Searches for SLC25A6 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SLC25A6 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 293 HGNC: 10992 AceView: SLC25A6.1 Ensembl:ENSG00000169100 euGenes: HUgn293
    ECgene: SLC25A6 Kegg: 293 H-InvDB: SLC25A6

    Other Databases showing SLC25A6 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC25A6 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC25A6 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC25A6 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC25A6 gene:
    Search GeneIP for patents involving SLC25A6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

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