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Aliases for SLC25A53 Gene

Aliases for SLC25A53 Gene

  • Solute Carrier Family 25, Member 53 2 3
  • Mitochondrial Carrier Triple Repeat Protein 6 3 4
  • MCART6 3 4
  • Mitochondrial Carrier Triple Repeat 6 2
  • Solute Carrier Family 25 Member 53 3

External Ids for SLC25A53 Gene

Previous HGNC Symbols for SLC25A53 Gene

  • MCART6

Previous GeneCards Identifiers for SLC25A53 Gene

  • GC0XM103344

Summaries for SLC25A53 Gene

GeneCards Summary for SLC25A53 Gene

SLC25A53 (Solute Carrier Family 25, Member 53) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC25A53 Gene

Genomics for SLC25A53 Gene

Genomic Location for SLC25A53 Gene

104,099,214 bp from pter
104,157,027 bp from pter
57,814 bases
Minus strand

Genomic View for SLC25A53 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC25A53 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC25A53 Gene

No data available for Regulatory Elements for SLC25A53 Gene

Proteins for SLC25A53 Gene

  • Protein details for SLC25A53 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Solute carrier family 25 member 53
    Protein Accession:
    Secondary Accessions:
    • B2RTT9

    Protein attributes for SLC25A53 Gene

    307 amino acids
    Molecular mass:
    34481 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC25A53 Gene

Proteomics data for SLC25A53 Gene at MOPED

Post-translational modifications for SLC25A53 Gene

No Post-translational modifications

Other Protein References for SLC25A53 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC25A53 Gene

Domains for SLC25A53 Gene

Gene Families for SLC25A53 Gene

Protein Domains for SLC25A53 Gene

Graphical View of Domain Structure for InterPro Entry



S2553_HUMAN :
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
  • Contains 3 Solcar repeats.
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
  • Contains 3 Solcar repeats.
genes like me logo Genes that share domains with SLC25A53: view

No data available for Suggested Antigen Peptide Sequences for SLC25A53 Gene

Function for SLC25A53 Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC25A53

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SLC25A53 Gene

Localization for SLC25A53 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC25A53 Gene

Mitochondrion inner membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SLC25A53 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005743 mitochondrial inner membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC25A53: view

No data available for Subcellular locations from COMPARTMENTS for SLC25A53 Gene

Pathways for SLC25A53 Gene

SuperPathways for SLC25A53 Gene

No Data Available

Interacting Proteins for SLC25A53 Gene

Gene Ontology (GO) - Biological Process for SLC25A53 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
genes like me logo Genes that share ontologies with SLC25A53: view

No data available for Pathways by source for SLC25A53 Gene

Transcripts for SLC25A53 Gene

mRNA/cDNA for SLC25A53 Gene

(4) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC25A53 Gene

Solute carrier family 25, member 53:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC25A53

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A53 Gene

No ASD Table

Relevant External Links for SLC25A53 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC25A53 Gene

mRNA expression in normal human tissues for SLC25A53 Gene

Protein differential expression in normal tissues for SLC25A53 Gene

This gene is overexpressed in CD8 Tcells (56.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SLC25A53 Gene

SOURCE GeneReport for Unigene cluster for SLC25A53 Gene Hs.660022

genes like me logo Genes that share expressions with SLC25A53: view

Expression partners for SLC25A53 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SLC25A53 Gene

Orthologs for SLC25A53 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLC25A53 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MCART6 35
  • 90.27 (n)
  • 91.15 (a)
(Canis familiaris)
Mammalia SLC25A53 35
  • 92.79 (n)
  • 95.41 (a)
(Mus musculus)
Mammalia Slc25a53 35
  • 86.95 (n)
  • 89.47 (a)
Slc25a53 16
(Rattus norvegicus)
Mammalia Mcart1l 35
  • 87.65 (n)
  • 92.13 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100489481 35
  • 57.72 (n)
  • 57.35 (a)
Species with no ortholog for SLC25A53:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SLC25A53 Gene

Gene Tree for SLC25A53 (if available)
Gene Tree for SLC25A53 (if available)

Paralogs for SLC25A53 Gene

(2) SIMAP similar genes for SLC25A53 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SLC25A53: view

No data available for Paralogs for SLC25A53 Gene

Variants for SLC25A53 Gene

Sequence variations from dbSNP and Humsavar for SLC25A53 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs144211923 -- 104,104,957(+) CAGGC(C/T)ATCAT reference, missense
rs143893825 -- 104,108,473(+) ATAAC(A/C)AGATA intron-variant
rs143839566 -- 104,147,150(+) GCCGC(A/T)TATCT intron-variant
rs143669435 -- 104,141,329(+) GAAAA(C/T)AAAGC intron-variant
rs143658025 -- 104,144,582(+) TATTC(A/G)GCCAT intron-variant

Relevant External Links for SLC25A53 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SLC25A53 Gene

Disorders for SLC25A53 Gene

No disorders were found for SLC25A53 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SLC25A53 Gene

Publications for SLC25A53 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  2. The mitochondrial transporter family SLC25: identification, properties and physiopathology. (PMID: 23266187) Palmieri F. (Mol. Aspects Med. 2013) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SLC25A53 Gene

Sources for SLC25A53 Gene

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