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Aliases for SLC25A52 Gene

Aliases for SLC25A52 Gene

  • Solute Carrier Family 25 Member 52 2 3 5
  • Mitochondrial Carrier Triple Repeat Protein 2 3 4
  • Mitochondrial Carrier Triple Repeat 2 2 3
  • Solute Carrier Family 25, Member 52 2 3
  • MCART2 3 4

External Ids for SLC25A52 Gene

Previous HGNC Symbols for SLC25A52 Gene

  • MCART2

Previous GeneCards Identifiers for SLC25A52 Gene

  • GC18M029340

Summaries for SLC25A52 Gene

Entrez Gene Summary for SLC25A52 Gene

  • This gene is similar to the mitochondrial carrier triple repeat 1 gene on chromosome 9. The gene is intronless and may be an evolving pseudogene; however, it is transcribed and it contains a full-length coding region so it is currently classified as a protein-coding locus. [provided by RefSeq, Jul 2008]

GeneCards Summary for SLC25A52 Gene

SLC25A52 (Solute Carrier Family 25 Member 52) is a Protein Coding gene. An important paralog of this gene is SLC25A51.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC25A52 Gene

Genomics for SLC25A52 Gene

Genomic Location for SLC25A52 Gene

Chromosome:
18
Start:
31,759,562 bp from pter
End:
31,760,880 bp from pter
Size:
1,319 bases
Orientation:
Minus strand

Genomic View for SLC25A52 Gene

Genes around SLC25A52 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC25A52 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC25A52 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC25A52 Gene

No data available for Regulatory Elements for SLC25A52 Gene

Proteins for SLC25A52 Gene

  • Protein details for SLC25A52 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q3SY17-S2552_HUMAN
    Recommended name:
    Solute carrier family 25 member 52
    Protein Accession:
    Q3SY17

    Protein attributes for SLC25A52 Gene

    Size:
    297 amino acids
    Molecular mass:
    33721 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC25A52 Gene

Proteomics data for SLC25A52 Gene at MOPED

Post-translational modifications for SLC25A52 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC25A52 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC25A52 Gene

Domains & Families for SLC25A52 Gene

Gene Families for SLC25A52 Gene

Protein Domains for SLC25A52 Gene

Suggested Antigen Peptide Sequences for SLC25A52 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q3SY17

UniProtKB/Swiss-Prot:

S2552_HUMAN :
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
  • Contains 3 Solcar repeats.
Family:
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
Similarity:
  • Contains 3 Solcar repeats.
genes like me logo Genes that share domains with SLC25A52: view

Function for SLC25A52 Gene

Phenotypes for SLC25A52 Gene

genes like me logo Genes that share phenotypes with SLC25A52: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SLC25A52 Gene

Localization for SLC25A52 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC25A52 Gene

Mitochondrion inner membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC25A52 Gene COMPARTMENTS Subcellular localization image for SLC25A52 gene
Compartment Confidence
mitochondrion 4
peroxisome 3
cytosol 2
golgi apparatus 1
nucleus 1

No data available for Gene Ontology (GO) - Cellular Components for SLC25A52 Gene

Pathways & Interactions for SLC25A52 Gene

SuperPathways for SLC25A52 Gene

No Data Available

Interacting Proteins for SLC25A52 Gene

Gene Ontology (GO) - Biological Process for SLC25A52 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SLC25A52 Gene

Drugs & Compounds for SLC25A52 Gene

No Compound Related Data Available

Transcripts for SLC25A52 Gene

mRNA/cDNA for SLC25A52 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC25A52 Gene

Solute carrier family 25, member 52:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A52 Gene

No ASD Table

Relevant External Links for SLC25A52 Gene

GeneLoc Exon Structure for
SLC25A52
ECgene alternative splicing isoforms for
SLC25A52

Expression for SLC25A52 Gene

mRNA expression in normal human tissues for SLC25A52 Gene

mRNA differential expression in normal tissues according to GTEx for SLC25A52 Gene

This gene is overexpressed in Testis (x34.4).

Protein differential expression in normal tissues from HIPED for SLC25A52 Gene

This gene is overexpressed in Fetal Brain (17.0), Heart (12.7), Frontal cortex (11.6), Placenta (10.2), CD4 Tcells (9.5), and CD8 Tcells (8.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SLC25A52 Gene



SOURCE GeneReport for Unigene cluster for SLC25A52 Gene Hs.567708

genes like me logo Genes that share expression patterns with SLC25A52: view

Protein tissue co-expression partners for SLC25A52 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SLC25A52 Gene

Orthologs for SLC25A52 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC25A52 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC25A52 35
  • 98.7 (n)
  • 97.72 (a)
SLC25A52 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MCART1 36
  • 91 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 93 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 76 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Slc25a51 36
  • 85 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 36
  • 68 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 72 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii zgc:73228 35
  • 62.53 (n)
  • 60.15 (a)
BX088718.1 36
  • 54 (a)
ManyToMany
CU638740.1 36
  • 54 (a)
ManyToMany
zgc:73228 36
  • 57 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta CG7943 36
  • 39 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea T20D3.5 36
  • 40 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 50 (a)
OneToMany
Species with no ortholog for SLC25A52:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for SLC25A52 Gene

ENSEMBL:
Gene Tree for SLC25A52 (if available)
TreeFam:
Gene Tree for SLC25A52 (if available)

Paralogs for SLC25A52 Gene

Paralogs for SLC25A52 Gene

(2) SIMAP similar genes for SLC25A52 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with SLC25A52: view

Variants for SLC25A52 Gene

Sequence variations from dbSNP and Humsavar for SLC25A52 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
VAR_060299 -

Variation tolerance for SLC25A52 Gene

Residual Variation Intolerance Score: 94.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.19; 52.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SLC25A52 Gene

HapMap Linkage Disequilibrium report
SLC25A52

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SLC25A52 Gene

Disorders for SLC25A52 Gene

Relevant External Links for SLC25A52

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SLC25A52

No disorders were found for SLC25A52 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC25A52 Gene

Publications for SLC25A52 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. The mitochondrial transporter family SLC25: identification, properties and physiopathology. (PMID: 23266187) Palmieri F. (Mol. Aspects Med. 2013) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SLC25A52 Gene

Sources for SLC25A52 Gene

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