Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SLC25A52 Gene

Aliases for SLC25A52 Gene

  • Solute Carrier Family 25, Member 52 2 3
  • Mitochondrial Carrier Triple Repeat Protein 2 3 4
  • Mitochondrial Carrier Triple Repeat 2 2 3
  • MCART2 3 4
  • Solute Carrier Family 25 Member 52 3

External Ids for SLC25A52 Gene

Previous HGNC Symbols for SLC25A52 Gene

  • MCART2

Previous GeneCards Identifiers for SLC25A52 Gene

  • GC18M029340

Summaries for SLC25A52 Gene

Entrez Gene Summary for SLC25A52 Gene

  • This gene is similar to the mitochondrial carrier triple repeat 1 gene on chromosome 9. The gene is intronless and may be an evolving pseudogene; however, it is transcribed and it contains a full-length coding region so it is currently classified as a protein-coding locus. [provided by RefSeq, Jul 2008]

GeneCards Summary for SLC25A52 Gene

SLC25A52 (Solute Carrier Family 25, Member 52) is a Protein Coding gene. An important paralog of this gene is SLC25A51.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC25A52 Gene

Genomics for SLC25A52 Gene

Genomic Location for SLC25A52 Gene

31,759,562 bp from pter
31,760,880 bp from pter
1,319 bases
Minus strand

Genomic View for SLC25A52 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC25A52 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC25A52 Gene

No data available for Regulatory Elements for SLC25A52 Gene

Proteins for SLC25A52 Gene

  • Protein details for SLC25A52 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Solute carrier family 25 member 52
    Protein Accession:
    Secondary Accessions:

    Protein attributes for SLC25A52 Gene

    297 amino acids
    Molecular mass:
    33721 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC25A52 Gene

Proteomics data for SLC25A52 Gene at MOPED

Post-translational modifications for SLC25A52 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC25A52 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC25A52 Gene

Domains for SLC25A52 Gene

Gene Families for SLC25A52 Gene

Protein Domains for SLC25A52 Gene

Graphical View of Domain Structure for InterPro Entry



S2552_HUMAN :
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
  • Contains 3 Solcar repeats.
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
  • Contains 3 Solcar repeats.
genes like me logo Genes that share domains with SLC25A52: view

No data available for Suggested Antigen Peptide Sequences for SLC25A52 Gene

Function for SLC25A52 Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC25A52

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SLC25A52 Gene

Localization for SLC25A52 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC25A52 Gene

Mitochondrion inner membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SLC25A52 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005743 mitochondrial inner membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC25A52: view

No data available for Subcellular locations from COMPARTMENTS for SLC25A52 Gene

Pathways for SLC25A52 Gene

SuperPathways for SLC25A52 Gene

No Data Available

Interacting Proteins for SLC25A52 Gene

Gene Ontology (GO) - Biological Process for SLC25A52 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
genes like me logo Genes that share ontologies with SLC25A52: view

No data available for Pathways by source for SLC25A52 Gene

Transcripts for SLC25A52 Gene

mRNA/cDNA for SLC25A52 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC25A52 Gene

Solute carrier family 25, member 52:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC25A52

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A52 Gene

No ASD Table

Relevant External Links for SLC25A52 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC25A52 Gene

mRNA expression in normal human tissues for SLC25A52 Gene

mRNA differential expression in normal tissues according to GTEx for SLC25A52 Gene

This gene is overexpressed in Testis (34.4).

Protein differential expression in normal tissues for SLC25A52 Gene

This gene is overexpressed in Fetal Brain (17.0), Heart (12.7), Frontal cortex (11.6), Placenta (10.2), CD4 Tcells (9.5), and CD8 Tcells (8.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SLC25A52 Gene

SOURCE GeneReport for Unigene cluster for SLC25A52 Gene Hs.567708

genes like me logo Genes that share expressions with SLC25A52: view

Expression partners for SLC25A52 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SLC25A52 Gene

Orthologs for SLC25A52 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC25A52 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SLC25A52 35
  • 98.7 (n)
  • 97.72 (a)
SLC25A52 36
  • 98 (a)
(Bos Taurus)
Mammalia MCART1 36
  • 91 (a)
(Canis familiaris)
Mammalia -- 36
  • 93 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 76 (a)
(Mus musculus)
Mammalia Slc25a51 36
  • 85 (a)
(Gallus gallus)
Aves -- 36
  • 68 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 72 (a)
(Danio rerio)
Actinopterygii zgc:73228 35
  • 62.53 (n)
  • 60.15 (a)
BX088718.1 36
  • 54 (a)
CU638740.1 36
  • 54 (a)
zgc:73228 36
  • 57 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7943 36
  • 39 (a)
(Caenorhabditis elegans)
Secernentea T20D3.5 36
  • 40 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 50 (a)
Species with no ortholog for SLC25A52:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for SLC25A52 Gene

Gene Tree for SLC25A52 (if available)
Gene Tree for SLC25A52 (if available)

Paralogs for SLC25A52 Gene

Paralogs for SLC25A52 Gene

(2) SIMAP similar genes for SLC25A52 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with SLC25A52: view

Variants for SLC25A52 Gene

Sequence variations from dbSNP and Humsavar for SLC25A52 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs1466503 -- 31,761,334(+) AGTAG(A/G)CCAGG upstream-variant-2KB
rs1466504 -- 31,761,528(+) TTTTT(A/T)AAAAA upstream-variant-2KB
rs3038918 -- 31,759,368(+) GACCT(-/TCT)CTCTG downstream-variant-500B
rs3038920 -- 31,759,541(+) aaaaa(-/AGAA)agaaa downstream-variant-500B
rs3859364 - 31,759,947(+) CTGTA(G/T)GCGAG missense, reference

Relevant External Links for SLC25A52 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SLC25A52 Gene

Disorders for SLC25A52 Gene

No disorders were found for SLC25A52 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SLC25A52 Gene

Publications for SLC25A52 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. The mitochondrial transporter family SLC25: identification, properties and physiopathology. (PMID: 23266187) Palmieri F. (Mol. Aspects Med. 2013) 3
  4. DNA sequence and analysis of human chromosome 18. (PMID: 16177791) Nusbaum C. … Lander E.S. (Nature 2005) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SLC25A52 Gene

Sources for SLC25A52 Gene

Back to Top