Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SLC25A51 Gene

Aliases for SLC25A51 Gene

  • Solute Carrier Family 25, Member 51 2 3
  • Mitochondrial Carrier Triple Repeat Protein 1 3 4
  • Mitochondrial Carrier Triple Repeat 1 2 3
  • MCART1 3 4
  • Solute Carrier Family 25 Member 51 3
  • CG7943 3

External Ids for SLC25A51 Gene

Previous HGNC Symbols for SLC25A51 Gene

  • MCART1

Summaries for SLC25A51 Gene

GeneCards Summary for SLC25A51 Gene

SLC25A51 (Solute Carrier Family 25, Member 51) is a Protein Coding gene. An important paralog of this gene is SLC25A52.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC25A51 Gene

Genomics for SLC25A51 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SLC25A51 Gene

Start:
37,877,575 bp from pter
End:
37,904,353 bp from pter
Size:
26,779 bases
Orientation:
Minus strand

Genomic View for SLC25A51 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC25A51 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC25A51 Gene

No data available for Regulatory Elements for SLC25A51 Gene

Proteins for SLC25A51 Gene

  • Protein details for SLC25A51 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H1U9-S2551_HUMAN
    Recommended name:
    Solute carrier family 25 member 51
    Protein Accession:
    Q9H1U9
    Secondary Accessions:

    Protein attributes for SLC25A51 Gene

    Size:
    297 amino acids
    Molecular mass:
    33672 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC25A51 Gene

Proteomics data for SLC25A51 Gene at MOPED

Post-translational modifications for SLC25A51 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC25A51 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC25A51 Gene

Domains for SLC25A51 Gene

Gene Families for SLC25A51 Gene

HGNC:
  • SLC :Solute carriers

Protein Domains for SLC25A51 Gene

Graphical View of Domain Structure for InterPro Entry

Q9H1U9

UniProtKB/Swiss-Prot:

S2551_HUMAN :
  • Q9H1U9
Family:
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
Similarity:
  • Contains 3 Solcar repeats.
genes like me logo Genes that share domains with SLC25A51: view

No data available for Suggested Antigen Peptide Sequences for SLC25A51 Gene

Function for SLC25A51 Gene

Animal Model Products

CRISPR Products

miRNA for SLC25A51 Gene

miRTarBase miRNAs that target SLC25A51

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC25A51

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SLC25A51 Gene

Localization for SLC25A51 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC25A51 Gene

Mitochondrion inner membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SLC25A51 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005743 mitochondrial inner membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC25A51: view

No data available for Subcellular locations from COMPARTMENTS for SLC25A51 Gene

Pathways for SLC25A51 Gene

SuperPathways for SLC25A51 Gene

No Data Available

Interacting Proteins for SLC25A51 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000242275%0d%0a9606.ENSP00000244769%0d%0a
Selected Interacting proteins: ENSP00000242275 for SLC25A51 Gene via STRING

Symbol External ID(s) Details
ATXN1

Gene Ontology (GO) - Biological Process for SLC25A51 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
genes like me logo Genes that share ontologies with SLC25A51: view

No data available for Pathways by source for SLC25A51 Gene

Transcripts for SLC25A51 Gene

Unigene Clusters for SLC25A51 Gene

Solute carrier family 25, member 51:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC25A51

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A51 Gene

No ASD Table

Relevant External Links for SLC25A51 Gene

GeneLoc Exon Structure for
SLC25A51
ECgene alternative splicing isoforms for
SLC25A51

Expression for SLC25A51 Gene

mRNA expression in normal human tissues for SLC25A51 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for SLC25A51 Gene

SOURCE GeneReport for Unigene cluster for SLC25A51 Gene Hs.634120

genes like me logo Genes that share expressions with SLC25A51: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SLC25A51 Gene

Orthologs for SLC25A51 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC25A51 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC25A51 35
  • 100 (n)
  • 100 (a)
SLC25A51 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MCART1 35
  • 92.03 (n)
  • 93.6 (a)
MCART1 36
  • 94 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 94 (a)
OneToMany
SLC25A51 35
  • 91.02 (n)
  • 93.94 (a)
mouse
(Mus musculus)
Mammalia Slc25a51 35
  • 80.7 (n)
  • 86.87 (a)
Slc25a51 16
Slc25a51 36
  • 87 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 78 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia LOC100909697 35
  • 81.82 (n)
  • 86.2 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 70 (a)
OneToMany
SLC25A51 35
  • 76.16 (n)
  • 79 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 74 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia slc25a51 35
  • 70.59 (n)
  • 74.75 (a)
zebrafish
(Danio rerio)
Actinopterygii BX088718.1 36
  • 55 (a)
ManyToMany
CU638740.1 36
  • 55 (a)
ManyToMany
LOC556422 35
  • 62.14 (n)
  • 62.26 (a)
zgc73228 35
zgc:73228 36
  • 57 (a)
ManyToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002280 35
  • 49.12 (n)
  • 42.11 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7943 35
  • 49.88 (n)
  • 44.03 (a)
CG7943 36
  • 38 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea T20D3.5 35
  • 51.85 (n)
  • 45.41 (a)
T20D3.5 36
  • 40 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 51 (a)
OneToMany
Species with no ortholog for SLC25A51:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC25A51 Gene

ENSEMBL:
Gene Tree for SLC25A51 (if available)
TreeFam:
Gene Tree for SLC25A51 (if available)

Paralogs for SLC25A51 Gene

Paralogs for SLC25A51 Gene

Selected SIMAP similar genes for SLC25A51 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for SLC25A51 Gene

genes like me logo Genes that share paralogs with SLC25A51: view

Variants for SLC25A51 Gene

Sequence variations from dbSNP and Humsavar for SLC25A51 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs776011 -- 37,879,133(+) ACATC(C/T)GCACA nc-transcript-variant
rs776012 -- 37,884,921(-) GTTCC(C/T)GTTTT intron-variant
rs776013 -- 37,885,375(+) CTTGT(A/T)TTTTC intron-variant
rs810246 -- 37,900,179(+) tggtg(A/G)ctcac intron-variant
rs811835 -- 37,900,198(+) tccca(G/T)cactt intron-variant

Relevant External Links for SLC25A51 Gene

HapMap Linkage Disequilibrium report
SLC25A51

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SLC25A51 Gene

Disorders for SLC25A51 Gene

No disorders were found for SLC25A51 Gene.

No data available for UniProtKB/Swiss-Prot for SLC25A51 Gene

Publications for SLC25A51 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3
  5. The mitochondrial transporter family SLC25: identification, properties and physiopathology. (PMID: 23266187) Palmieri F. (Mol. Aspects Med. 2013) 3

Products for SLC25A51 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate SLC25A51
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SLC25A51
    • Block miRNA regulation of SLC25A51 using miScript Target Protectors

    Sources for SLC25A51 Gene

    Back to Top

    Content