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Aliases for SLC25A51 Gene

Aliases for SLC25A51 Gene

  • Solute Carrier Family 25 Member 51 2 3 5
  • Mitochondrial Carrier Triple Repeat Protein 1 3 4
  • Mitochondrial Carrier Triple Repeat 1 2 3
  • Solute Carrier Family 25, Member 51 2 3
  • MCART1 3 4
  • CG7943 3

External Ids for SLC25A51 Gene

Previous HGNC Symbols for SLC25A51 Gene

  • MCART1

Summaries for SLC25A51 Gene

GeneCards Summary for SLC25A51 Gene

SLC25A51 (Solute Carrier Family 25 Member 51) is a Protein Coding gene. An important paralog of this gene is SLC25A52.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC25A51 Gene

Genomics for SLC25A51 Gene

Regulatory Elements for SLC25A51 Gene

Enhancers for SLC25A51 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SLC25A51 on UCSC Golden Path with GeneCards custom track

Promoters for SLC25A51 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SLC25A51 on UCSC Golden Path with GeneCards custom track

Genomic Location for SLC25A51 Gene

37,877,575 bp from pter
37,904,353 bp from pter
26,779 bases
Minus strand

Genomic View for SLC25A51 Gene

Genes around SLC25A51 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC25A51 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC25A51 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC25A51 Gene

Proteins for SLC25A51 Gene

  • Protein details for SLC25A51 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Solute carrier family 25 member 51
    Protein Accession:

    Protein attributes for SLC25A51 Gene

    297 amino acids
    Molecular mass:
    33672 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC25A51 Gene

Proteomics data for SLC25A51 Gene at MOPED

Post-translational modifications for SLC25A51 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC25A51 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC25A51 Gene

Domains & Families for SLC25A51 Gene

Gene Families for SLC25A51 Gene

Protein Domains for SLC25A51 Gene

Suggested Antigen Peptide Sequences for SLC25A51 Gene

Graphical View of Domain Structure for InterPro Entry



S2551_HUMAN :
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
  • Contains 3 Solcar repeats.
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
  • Contains 3 Solcar repeats.
genes like me logo Genes that share domains with SLC25A51: view

Function for SLC25A51 Gene

genes like me logo Genes that share phenotypes with SLC25A51: view

Animal Model Products

  • Taconic Biosciences Mouse Models for SLC25A51

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC25A51 Gene

Localization for SLC25A51 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC25A51 Gene

Mitochondrion inner membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SLC25A51 Gene COMPARTMENTS Subcellular localization image for SLC25A51 gene
Compartment Confidence
mitochondrion 4
peroxisome 3
cytosol 2
golgi apparatus 1
nucleus 1

No data available for Gene Ontology (GO) - Cellular Components for SLC25A51 Gene

Pathways & Interactions for SLC25A51 Gene

SuperPathways for SLC25A51 Gene

No Data Available

Interacting Proteins for SLC25A51 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000242275 for SLC25A51 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for SLC25A51 Gene


No data available for Pathways by source and SIGNOR curated interactions for SLC25A51 Gene

Drugs & Compounds for SLC25A51 Gene

No Compound Related Data Available

Transcripts for SLC25A51 Gene

Unigene Clusters for SLC25A51 Gene

Solute carrier family 25, member 51:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A51 Gene

No ASD Table

Relevant External Links for SLC25A51 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC25A51 Gene

mRNA expression in normal human tissues for SLC25A51 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for SLC25A51 Gene

This gene is overexpressed in Frontal cortex (21.8), Heart (21.6), Blymphocyte (14.0), and Retina (11.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for SLC25A51 Gene

SOURCE GeneReport for Unigene cluster for SLC25A51 Gene Hs.634120

genes like me logo Genes that share expression patterns with SLC25A51: view

Protein tissue co-expression partners for SLC25A51 Gene

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SLC25A51 Gene

Orthologs for SLC25A51 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC25A51 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MCART1 35
  • 92.03 (n)
  • 93.6 (a)
  • 94 (a)
(Canis familiaris)
Mammalia SLC25A51 35
  • 91.02 (n)
  • 93.94 (a)
-- 36
  • 94 (a)
(Mus musculus)
Mammalia Slc25a51 35
  • 80.7 (n)
  • 86.87 (a)
Slc25a51 16
Slc25a51 36
  • 87 (a)
(Pan troglodytes)
Mammalia SLC25A51 35
  • 100 (n)
  • 100 (a)
SLC25A51 36
  • 100 (a)
(Rattus norvegicus)
Mammalia LOC100909697 35
  • 81.82 (n)
  • 86.2 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 78 (a)
(Gallus gallus)
Aves SLC25A51 35
  • 76.16 (n)
  • 79 (a)
-- 36
  • 70 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 74 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia slc25a51 35
  • 70.59 (n)
  • 74.75 (a)
(Danio rerio)
Actinopterygii LOC556422 35
  • 62.14 (n)
  • 62.26 (a)
zgc73228 35
BX088718.1 36
  • 55 (a)
CU638740.1 36
  • 55 (a)
zgc:73228 36
  • 57 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002280 35
  • 49.12 (n)
  • 42.11 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7943 35
  • 49.88 (n)
  • 44.03 (a)
CG7943 36
  • 38 (a)
(Caenorhabditis elegans)
Secernentea T20D3.5 35
  • 51.85 (n)
  • 45.41 (a)
T20D3.5 36
  • 40 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 51 (a)
Species with no ortholog for SLC25A51:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC25A51 Gene

Gene Tree for SLC25A51 (if available)
Gene Tree for SLC25A51 (if available)

Paralogs for SLC25A51 Gene

Paralogs for SLC25A51 Gene

(2) SIMAP similar genes for SLC25A51 Gene using alignment to 1 proteins: Pseudogenes for SLC25A51 Gene

genes like me logo Genes that share paralogs with SLC25A51: view

Variants for SLC25A51 Gene

Sequence variations from dbSNP and Humsavar for SLC25A51 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
VAR_036333 A breast cancer sample
rs776011 -- 37,879,133(+) ACATC(C/T)GCACA nc-transcript-variant
rs776012 -- 37,884,921(-) GTTCC(C/T)GTTTT intron-variant
rs776013 -- 37,885,375(+) CTTGT(A/T)TTTTC intron-variant
rs810246 -- 37,900,179(+) tggtg(A/G)ctcac intron-variant

Variation tolerance for SLC25A51 Gene

Residual Variation Intolerance Score: 45.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.63; 13.48% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SLC25A51 Gene

Disorders for SLC25A51 Gene

Relevant External Links for SLC25A51

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SLC25A51 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC25A51 Gene

Publications for SLC25A51 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. The mitochondrial transporter family SLC25: identification, properties and physiopathology. (PMID: 23266187) Palmieri F. (Mol. Aspects Med. 2013) 3
  5. Development and application of a DNA microarray-based yeast two-hybrid system. (PMID: 23275563) Suter B. … Wanker E.E. (Nucleic Acids Res. 2013) 3

Products for SLC25A51 Gene

Sources for SLC25A51 Gene