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Aliases for SLC25A48 Gene

Aliases for SLC25A48 Gene

  • Solute Carrier Family 25, Member 48 2 3
  • HCC-Down-Regulated Mitochondrial Carrier Protein 2

External Ids for SLC25A48 Gene

Summaries for SLC25A48 Gene

GeneCards Summary for SLC25A48 Gene

SLC25A48 (Solute Carrier Family 25, Member 48) is a Protein Coding gene. An important paralog of this gene is SLC25A20.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC25A48 Gene

Genomics for SLC25A48 Gene

Genomic Location for SLC25A48 Gene

Start:
135,834,649 bp from pter
End:
135,888,637 bp from pter
Size:
53,989 bases
Orientation:
Plus strand

Genomic View for SLC25A48 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC25A48 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC25A48 Gene

No data available for Regulatory Elements for SLC25A48 Gene

Proteins for SLC25A48 Gene

  • Protein details for SLC25A48 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZT89-S2548_HUMAN
    Recommended name:
    Solute carrier family 25 member 48
    Protein Accession:
    Q6ZT89
    Secondary Accessions:
    • Q8TAV9

    Protein attributes for SLC25A48 Gene

    Size:
    311 amino acids
    Molecular mass:
    33440 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLC25A48 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC25A48 Gene

Proteomics data for SLC25A48 Gene at MOPED

Post-translational modifications for SLC25A48 Gene

No Post-translational modifications

Other Protein References for SLC25A48 Gene

No data available for DME Specific Peptides for SLC25A48 Gene

Domains for SLC25A48 Gene

Gene Families for SLC25A48 Gene

HGNC:
  • SLC :Solute carriers

Protein Domains for SLC25A48 Gene

UniProtKB/Swiss-Prot:

S2548_HUMAN
Family:
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.:
    • Q6ZT89
Similarity:
  • Contains 3 Solcar repeats.:
    • Q6ZT89
genes like me logo Genes that share domains with SLC25A48: view

Function for SLC25A48 Gene

Gene Ontology (GO) - Molecular Function for SLC25A48 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with SLC25A48: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SLC25A48 Gene

Localization for SLC25A48 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC25A48 Gene

Mitochondrion inner membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC25A48 Gene COMPARTMENTS Subcellular localization image for SLC25A48 gene
Compartment Confidence
mitochondrion 5
cytoskeleton 1
cytosol 1
endoplasmic reticulum 1
extracellular 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for SLC25A48 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion --
GO:0005743 mitochondrial inner membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC25A48: view

Pathways for SLC25A48 Gene

SuperPathways for SLC25A48 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SLC25A48 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport --
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC25A48: view

No data available for Pathways by source for SLC25A48 Gene

Transcripts for SLC25A48 Gene

Unigene Clusters for SLC25A48 Gene

Solute carrier family 25, member 48:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A48 Gene

No ASD Table

Relevant External Links for SLC25A48 Gene

GeneLoc Exon Structure for
SLC25A48
ECgene alternative splicing isoforms for
SLC25A48

Expression for SLC25A48 Gene

mRNA expression in normal human tissues for SLC25A48 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC25A48 Gene

This gene is overexpressed in Nerve - Tibial (12.3), Brain - Amygdala (4.3), and Brain - Hippocampus (4.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SLC25A48 Gene

SOURCE GeneReport for Unigene cluster for SLC25A48 Gene Hs.412418

genes like me logo Genes that share expressions with SLC25A48: view

Orthologs for SLC25A48 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SLC25A48 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC25A48 37
  • 47 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SLC25A48 37
  • 42 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLC25A48 37
  • 44 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc25a48 16
Slc25a48 37
  • 41 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLC25A48 37
  • 39 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SLC25A48 37
  • 8 (a)
OneToOne
chicken
(Gallus gallus)
Aves SLC25A48 37
  • 29 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC25A48 37
  • 34 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.8530 36
zebrafish
(Danio rerio)
Actinopterygii Dr.28307 36
slc25a48 37
  • 31 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG5646 37
  • 16 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea R07B7.10 37
  • 18 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes YMC1 37
  • 14 (a)
ManyToMany
YMC2 37
  • 16 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 21 (a)
OneToOne
Species with no ortholog for SLC25A48:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC25A48 Gene

ENSEMBL:
Gene Tree for SLC25A48 (if available)
TreeFam:
Gene Tree for SLC25A48 (if available)

Paralogs for SLC25A48 Gene

Paralogs for SLC25A48 Gene

Selected SIMAP similar genes for SLC25A48 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with SLC25A48: view

Variants for SLC25A48 Gene

Sequence variations from dbSNP and Humsavar for SLC25A48 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs25895 -- 135,882,121(-) AAAGA(A/G)CGCTT intron-variant
rs25896 -- 135,881,636(-) TATCT(C/G)AGCAC intron-variant
rs25897 -- 135,878,737(-) AAGTT(A/T)AAGAA intron-variant
rs25898 -- 135,877,516(-) CGTGA(A/C)AAAGG intron-variant
rs25899 -- 135,877,462(-) TTTCC(A/C/T)GGAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC25A48 Gene

Variant ID Type Subtype PubMed ID
nsv508380 CNV Loss 20534489
dgv1853e1 CNV Complex 17122850

Relevant External Links for SLC25A48 Gene

HapMap Linkage Disequilibrium report
SLC25A48

Disorders for SLC25A48 Gene

Relevant External Links for SLC25A48

Human Genome Epidemiology (HuGE) Navigator
SLC25A48
genes like me logo Genes that share disorders with SLC25A48: view

No data available for UniProtKB/Swiss-Prot for SLC25A48 Gene

Publications for SLC25A48 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3
  4. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3
  5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3

Products for SLC25A48 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate SLC25A48
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SLC25A48
    • Block miRNA regulation of SLC25A48 using miScript Target Protectors

    Sources for SLC25A48 Gene

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