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SLC25A47 Gene

protein-coding   GIFtS: 47
GCID: GC14P101225

Solute Carrier Family 25, Member 47

(Previous name: chromosome 14 open reading frame 68)
(Previous symbol: C14orf68)
  See SLC25A47-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 25, Member 471 2     Chromosome 14 Open Reading Frame 681
C14orf681 2 3 5     HCC-Down-Regulated Mitochondrial Carrier Protein2
HDMCP2 3 5     Hepatocellular Carcinoma-Downregulated Mitochondrial Carrier Protein2
Hepatocellular Carcinoma Down-Regulated Mitochondrial Carrier Protein2 3     Solute Carrier Family 25 Member 472

External Ids:    HGNC: 201151   Entrez Gene: 2836002   Ensembl: ENSG000001401077   OMIM: 6099115   UniProtKB: Q6Q0C13   

Export aliases for SLC25A47 gene to outside databases

Previous GC identifers: GC14P101010 GC14P080971 GC14P101022 GC14P101033 GC14P101047 GC14P101077 GC14P101114 GC14P101163


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SLC25A47 Gene:
SLC25A47 (solute carrier family 25, member 47) is a protein-coding gene. Diseases associated with SLC25A47 include hepatocellular carcinoma. An important paralog of this gene is SLC25A45.

UniProtKB/Swiss-Prot: S2547_HUMAN, Q6Q0C1
Function: Uncoupling protein which may catalyze the physiological 'proton leak' in liver. Overexpression induces
the dissipation of mitochondrial membrane potential




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SLC25A47
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SLC25A47

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC25A47


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.2   Ensembl cytogenetic band:  14q32.2   HGNC cytogenetic band: 14q32.2

SLC25A47 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A47 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P101225:  view genomic region     (about GC identifiers)

Start:
100,789,674 bp from pter      End:
100,796,715 bp from pter
Size:
7,042 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: S2547_HUMAN, Q6Q0C1 (See protein sequence)
Recommended Name: Solute carrier family 25 member 47  
Size: 308 amino acids; 33435 Da
Sequence caution: Sequence=BAD38636.1; Type=Erroneous translation; Note=Wrong choice of frame;
Sequence=CAD62588.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B2RP39 Q68CL2 Q6PZD8 Q86U14
Alternative splicing: 2 isoforms:  Q6Q0C1-1   Q6Q0C1-2   

Explore the universe of human proteins at neXtProt for SLC25A47: NX_Q6Q0C1

Explore proteomics data for SLC25A47 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SLC25A47 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_997000.2  
    ENSEMBL proteins: 
     ENSP00000354886   ENSP00000451078  

    SLC25A47 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for SLC25A47

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    3 InterPro protein domains:
     IPR002067 Mit_carrier
     IPR023395 Mt_carrier_dom
     IPR018108 Mitochondrial_sb/sol_carrier

    Graphical View of Domain Structure for InterPro Entry Q6Q0C1

    ProtoNet protein and cluster: Q6Q0C1

    UniProtKB/Swiss-Prot: S2547_HUMAN, Q6Q0C1
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 3 Solcar repeats


    Find genes that share domains with SLC25A47           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S2547_HUMAN, Q6Q0C1
    Function: Uncoupling protein which may catalyze the physiological 'proton leak' in liver. Overexpression induces
    the dissipation of mitochondrial membrane potential
    Induction: Down-regulated in hepatocarcinoma

    Phenotypes:
         1 GenomeRNAi human phenotype for SLC25A47:

     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC25A47
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC25A47
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    S2547_HUMAN, Q6Q0C1: Mitochondrion inner membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    extracellular2
    plasma membrane2
    cytosol1
    endoplasmic reticulum1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with SLC25A47           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC25A47
    Interactions:

        Search GeneGlobe Interaction Network for SLC25A47

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for SLC25A47 (ENSP000003548864) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NOP56ENSP000003705894STRING: ENSP00000370589
    C1QAENSP000003637734STRING: ENSP00000363773
    DIABLOENSP000002671694STRING: ENSP00000267169
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0055085transmembrane transport IEA--

    Find genes that share ontologies with SLC25A47           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC25A47 (S2547)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SLC25A47 gene: 
    NM_207117.2  

    Unigene Cluster for SLC25A47:

    Solute carrier family 25, member 47
    Hs.108268  [show with all ESTs]
    Unigene Representative Sequence: AY569438
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361529(uc001yhc.3 uc001yhd.3) ENST00000557052
    miRNA
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      QuantiFast Probe-based Assays in human, mouse, rat SLC25A47

    Additional mRNA sequence: 

    AB073385.1 AK092001.1 AY569438.1 AY570298.1 BC137253.1 BC137254.1 BC144549.1 BX248260.1 

    4 DOTS entries:

    DT.99998920  DT.100643803  DT.120776516  DT.120776523 

    Selected AceView cDNA sequences (see all 28):

    BX445867 AY569438 H59765 CR624455 CR607410 NM_207117 BX248260 AY570298 
    BX444082 AX747302 BX106119 BX429963 AB073385 H65661 H59766 AK092001 
    BX447978 BX452434 BX450401 H57059 BX450786 BX443918 AI033511 H57060 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A47    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6
    SP1:                    -                           
    SP2:                                                


    ECgene alternative splicing isoforms for SLC25A47

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC25A47 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SLC25A47 Expression
    About this image


    SLC25A47 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Liver (Hepatobiliary System)
             Periportal Hepatocytes Liver Lobule
    SLC25A47 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC25A47 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.108268

    UniProtKB/Swiss-Prot: S2547_HUMAN, Q6Q0C1
    Tissue specificity: Specifically expressed in liver

        Custom PCR Arrays for SLC25A47
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC25A47 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc25a471 , 5 solute carrier family 25, member 471, 5 83.33(n)1
    88.31(a)1
      12 (59.65 cM)5
    1049101  NM_001012310.21  NP_001012310.21 
     1088511295 
    chicken
    (Gallus gallus)
    Aves SLC25A471 solute carrier family 25, member 47 64.58(n)
    63.76(a)
      423457  XM_421367.4  XP_421367.3 
    lizard
    (Anolis carolinensis)
    Reptilia SLC25A476
    solute carrier family 25, member 47
    58(a)
    1 ↔ 1
    GL343270.1(928398-934997)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia slc25a471 solute carrier family 25, member 47 57.55(n)
    61.25(a)
      100496270  XM_004917171.1  XP_004917228.1 
    zebrafish
    (Danio rerio)
    Actinopterygii slc25a47b1 solute carrier family 25, member 47b 58.45(n)
    57.04(a)
      100006442  NM_001089581.1  NP_001083050.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG56466
    --
    31(a)
    1 → many
    3R(23385101-23387041)
    worm
    (Caenorhabditis elegans)
    Secernentea R07B7.106
    Protein R07B7.10 (R07B7.10) mRNA, complete cds
    34(a)
    1 → many
    V(12084426-12086328) WBGene00011094
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YMC16
    YMC26
    Mitochondrial protein, putative inner membrane tra...
    Mitochondrial protein, putative inner membrane tra...
    28(a)
    26(a)
    many ↔ many
    many ↔ many
    XVI(673751-674674) YPR058W
    II(449667-450656) YBR104W


    ENSEMBL Gene Tree for SLC25A47 (if available)
    TreeFam Gene Tree for SLC25A47 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC25A47 gene
    SLC25A452  SLC25A202  SLC25A482  SLC25A292  
    10 SIMAP similar genes for SLC25A47 using alignment to 2 protein entries:     S2547_HUMAN (see all proteins):
    SLC25A48    FLJ00351    LOC283130    SLC25A45    SLC25A29    UCP2
    SLC25A1    SLC25A11    SLC25A20    SLC25A15

    Find genes that share paralogs with SLC25A47           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for SLC25A47
    PGOHUM00000261833


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC25A47 (see all 305)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1173075271,2
    C,Funtested1100793550(+) CCTCTC/G/TGCTGC 2 S L mis11EA 120
    rs1456868991,2
    --100787714(+) CACAGA/GACTGG 1 -- us2k10--------
    rs1834111301,2
    --100787939(+) AAGTCC/TCAGCT 1 -- us2k10--------
    rs71416341,2
    C,F,A--100788014(+) GCAGCA/CTTAGC 1 -- us2k18Minor allele frequency- C:0.25NA WA CSA EA 368
    rs556886881,2
    C,F--100788051(+) ACGCCC/TGGACT 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1470618831,2
    C--100788066(+) CCTGCA/GTGGTC 1 -- us2k10--------
    rs1865315341,2
    --100788104(+) TTTCAC/TGGATG 1 -- us2k10--------
    rs1381529381,2
    --100788149(+) CCCACA/GGTCTC 1 -- us2k10--------
    rs356179681,2
    C,F--100788223(+) TCATCC/ACCTTG 1 -- us2k17Minor allele frequency- A:0.19NA WA EA 366
    rs1114848881,2
    F--100788231(+) TTGAGG/AGCCAG 1 -- us2k11Minor allele frequency- A:0.50CSA 2

    HapMap Linkage Disequilibrium report for SLC25A47 (100789674 - 100796715 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SLC25A47:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv832875CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC25A47
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC25A47

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609911    OMIM disorders: --

    1 disease for SLC25A47:    
    About MalaCards
    hepatocellular carcinoma


    Find genes that share disorders with SLC25A47           About GenesLikeMe

    Genetic Association Database (GAD): SLC25A47
    Human Genome Epidemiology (HuGE) Navigator: SLC25A47 (1 document)

    Export disorders for SLC25A47 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC25A47 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SLC25A47)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and identification of hepatocellular carcinoma down-regulated mitochondrial carrier protein, a novel liver-specific uncoupling protein. (PubMed id 15322095)1, 2, 9 Tan M.G.K.... Hui K.M. (J. Biol. Chem. 2004)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. (PubMed id 15221005)1, 2 Yamada S....Nakagawara A. (Oncogene 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The mitochondrial transporter family SLC25: identification, properties and physiopathology. (PubMed id 23266187)1 Palmieri F. (Mol. Aspects Med. 2013)
    6. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    7. HDMCP uncouples yeast mitochondrial respiration and alleviates steatosis in L02 and hepG2 cells by decreasing ATP and H2O2 levels: a novel mechanism for NAFLD. (PubMed id 19303656)1 Jin X....Li Y.M. (J. Hepatol. 2009)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 283600 HGNC: 20115 AceView: C14orf68 Ensembl:ENSG00000140107 euGenes: HUgn283600
    ECgene: SLC25A47 H-InvDB: SLC25A47

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC25A47 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC25A47 gene:
    Search GeneIP for patents involving SLC25A47

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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