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Aliases for SLC25A44 Gene

Aliases for SLC25A44 Gene

  • Solute Carrier Family 25, Member 44 2 3
  • KIAA0446 4

External Ids for SLC25A44 Gene

Previous GeneCards Identifiers for SLC25A44 Gene

  • GC01P154432
  • GC01P127525

Summaries for SLC25A44 Gene

Entrez Gene Summary for SLC25A44 Gene

  • SLC25A44 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008]

GeneCards Summary for SLC25A44 Gene

SLC25A44 (Solute Carrier Family 25, Member 44) is a Protein Coding gene. An important paralog of this gene is SLC25A13.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC25A44 Gene

Genomics for SLC25A44 Gene

Regulatory Elements for SLC25A44 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SLC25A44 Gene

156,193,932 bp from pter
156,212,796 bp from pter
18,865 bases
Plus strand

Genomic View for SLC25A44 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC25A44 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC25A44 Gene

Proteins for SLC25A44 Gene

  • Protein details for SLC25A44 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Solute carrier family 25 member 44
    Protein Accession:
    Secondary Accessions:
    • O75034

    Protein attributes for SLC25A44 Gene

    314 amino acids
    Molecular mass:
    35392 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA32291.3; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for SLC25A44 Gene

Proteomics data for SLC25A44 Gene at MOPED

Post-translational modifications for SLC25A44 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC25A44 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for SLC25A44 Gene

Domains for SLC25A44 Gene

Gene Families for SLC25A44 Gene

Protein Domains for SLC25A44 Gene

Graphical View of Domain Structure for InterPro Entry



S2544_HUMAN :
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
  • Contains 3 Solcar repeats.
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
  • Contains 3 Solcar repeats.
genes like me logo Genes that share domains with SLC25A44: view

Function for SLC25A44 Gene

Animal Model Products

CRISPR Products

miRNA for SLC25A44 Gene

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC25A44

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC25A44 Gene

Localization for SLC25A44 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC25A44 Gene

Mitochondrion inner membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SLC25A44 Gene COMPARTMENTS Subcellular localization image for SLC25A44 gene
Compartment Confidence
mitochondrion 5
cytoskeleton 3
peroxisome 2
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for SLC25A44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion --
GO:0005743 mitochondrial inner membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC25A44: view

Pathways for SLC25A44 Gene

SuperPathways for SLC25A44 Gene

No Data Available

Interacting Proteins for SLC25A44 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000352497 for SLC25A44 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for SLC25A44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC25A44: view

No data available for Pathways by source for SLC25A44 Gene

Transcripts for SLC25A44 Gene

Unigene Clusters for SLC25A44 Gene

Solute carrier family 25, member 44:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC25A44

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A44 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c · 9d · 9e
SP1: - - - - - - -
SP2: - - - - - -
SP3: -
SP4: - - - - - - - - - -
SP6: -
SP7: - - - - - - - - - - -
SP8: - -
SP10: - -

Relevant External Links for SLC25A44 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC25A44 Gene

mRNA expression in normal human tissues for SLC25A44 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC25A44 Gene

This gene is overexpressed in Whole Blood (6.1).

Protein differential expression in normal tissues for SLC25A44 Gene

This gene is overexpressed in Plasma (62.0).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for SLC25A44 Gene

SOURCE GeneReport for Unigene cluster for SLC25A44 Gene Hs.532375

genes like me logo Genes that share expressions with SLC25A44: view

Expression partners for SLC25A44 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for SLC25A44 Gene

Orthologs for SLC25A44 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SLC25A44 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SLC25A44 35
  • 92.99 (n)
  • 98.73 (a)
SLC25A44 36
  • 99 (a)
(Canis familiaris)
Mammalia SLC25A44 35
  • 92.14 (n)
  • 97.13 (a)
SLC25A44 36
  • 89 (a)
(Mus musculus)
Mammalia Slc25a44 35
  • 90.02 (n)
  • 96.18 (a)
Slc25a44 16
Slc25a44 36
  • 91 (a)
(Pan troglodytes)
Mammalia SLC25A44 35
  • 100 (n)
  • 100 (a)
SLC25A44 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Slc25a44 35
  • 90.13 (n)
  • 96.18 (a)
(Monodelphis domestica)
Mammalia SLC25A44 36
  • 77 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 23 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia slc25a44 35
  • 76.36 (n)
  • 85.62 (a)
Str.7069 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.3595 35
(Danio rerio)
Actinopterygii Dr.26870 35
slc25a44b 35
  • 70.06 (n)
  • 75.48 (a)
slc25a44a 36
  • 71 (a)
slc25a44b 36
  • 75 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3005 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003208 35
  • 51.69 (n)
  • 42.3 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5805 35
  • 52.18 (n)
  • 39.62 (a)
CG5805 36
  • 36 (a)
(Caenorhabditis elegans)
Secernentea F13G3.7 35
  • 46.62 (n)
  • 35.37 (a)
F13G3.7 36
  • 27 (a)
Y43C5B.3 36
  • 29 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes AGC1 36
  • 8 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G15640 35
  • 46.34 (n)
  • 37.23 (a)
(Oryza sativa)
Liliopsida Os03g0754800 35
  • 49.2 (n)
  • 40.34 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 36 (a)
Species with no ortholog for SLC25A44:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC25A44 Gene

Gene Tree for SLC25A44 (if available)
Gene Tree for SLC25A44 (if available)

Paralogs for SLC25A44 Gene

Paralogs for SLC25A44 Gene

genes like me logo Genes that share paralogs with SLC25A44: view

Variants for SLC25A44 Gene

Sequence variations from dbSNP and Humsavar for SLC25A44 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs545343268 -- 156,209,525(+) TGGCC(A/G)AGGGG intron-variant
rs546329740 -- 156,209,430(+) GGAAG(C/T)GGGGG intron-variant
rs546460095 -- 156,195,230(+) TCCCG(A/G)GTAGC intron-variant
rs545299523 -- 156,209,224(+) TGGGC(A/G)TTCTA intron-variant
rs545182331 -- 156,207,045(+) TTAAA(C/T)GGACG intron-variant

Relevant External Links for SLC25A44 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SLC25A44 Gene

Disorders for SLC25A44 Gene

Relevant External Links for SLC25A44

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for SLC25A44 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for SLC25A44 Gene

Publications for SLC25A44 Gene

  1. Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system. (PMID: 16949250) Haitina T. … Fredriksson R. (Genomics 2006) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PMID: 16303743) Otsuki T. … Isogai T. (DNA Res. 2005) 3 4
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  5. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 48

Products for SLC25A44 Gene

Sources for SLC25A44 Gene

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