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SLC25A40 Gene

protein-coding   GIFtS: 48
GCID: GC07M087462

Solute Carrier Family 25, Member 40

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 25, Member 401 2
Mitochondrial Carrier Family Protein2 3
MCFP2 3
Solute Carrier Family 25 Member 402

External Ids:    HGNC: 296801   Entrez Gene: 559722   Ensembl: ENSG000000753037   OMIM: 6108215   UniProtKB: Q8TBP63   

Export aliases for SLC25A40 gene to outside databases

Previous GC identifers: GC07M087304 GC07M082073


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC25A40 Gene:
SLC25A40 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 (PubMed
16949250)).(supplied by OMIM, Mar 2008)

GeneCards Summary for SLC25A40 Gene:
SLC25A40 (solute carrier family 25, member 40) is a protein-coding gene. An important paralog of this gene is SLC25A39.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC25A40 gene promoter:
         AP-1   POU3F1   Evi-1   YY1   GATA-1   CREB   POU2F1a   deltaCREB   POU2F1b   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC25A40 promoter sequence
   Search Chromatin IP Primers for SLC25A40

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC25A40


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q21.12   Ensembl cytogenetic band:  7q21.12   HGNC cytogenetic band: 7q21.12

SLC25A40 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A40 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M087462:  view genomic region     (about GC identifiers)

Start:
87,462,883 bp from pter      End:
87,505,692 bp from pter
Size:
42,810 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 86,795,132-86,837,010     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: S2540_HUMAN, Q8TBP6 (See protein sequence)
Recommended Name: Solute carrier family 25 member 40  
Size: 338 amino acids; 38125 Da
Secondary accessions: A8K483 D6W5P6 Q53GB1 Q9UHR1

Explore the universe of human proteins at neXtProt for SLC25A40: NX_Q8TBP6

Explore proteomics data for SLC25A40 at MOPED


See SLC25A40 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_061331.2  
ENSEMBL proteins: 
 ENSP00000344831   ENSP00000401473   ENSP00000405566   ENSP00000407780  

SLC25A40 Human Recombinant Protein Products:

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Cloud-Clone Corp. Proteins for SLC25A40

 
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antibodies-online proteins for SLC25A40 (2 products) 

 
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antibodies-online antibodies for SLC25A40 

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antibodies-online kits for SLC25A40 (8 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
SLC: Solute carriers

IUPHAR Guide to PHARMACOLOGY protein family classification: MCFP
Miscellaneous SLC25 mitochondrial transporters

3 InterPro protein domains:
 IPR002067 Mit_carrier
 IPR023395 Mt_carrier_dom
 IPR018108 Mitochondrial_sb/sol_carrier

Graphical View of Domain Structure for InterPro Entry Q8TBP6

ProtoNet protein and cluster: Q8TBP6

UniProtKB/Swiss-Prot: S2540_HUMAN, Q8TBP6
Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
Similarity: Contains 3 Solcar repeats


Find genes that share domains with SLC25A40           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Phenotypes:
     1 GenomeRNAi human phenotype for SLC25A40:
 Increased cell number in G1, a 

     1 MGI mutant phenotype (inferred from 1 allele(MGI details for Slc25a40):
 normal 

Find genes that share phenotypes with SLC25A40           About GenesLikeMe

Animal Models:
   genOway: Develop your customized and physiologically relevant rodent model for SLC25A40

miRNA
Products:
    
miRTarBase miRNAs that target SLC25A40:
hsa-mir-215-5p (MIRT024941), hsa-mir-328-3p (MIRT043799), hsa-mir-192-5p (MIRT026648), hsa-mir-155-5p (MIRT005248)

Block miRNA regulation of human, mouse, rat SLC25A40 using miScript Target Protectors
6 qRT-PCR Assays for microRNAs that regulate SLC25A40:
hsa-miR-23b hsa-miR-130a* hsa-miR-494 hsa-miR-23a hsa-miR-23c hsa-miR-551b*
SwitchGear 3'UTR luciferase reporter plasmidSLC25A40 3' UTR sequence
Inhib. RNA
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OriGene RNAi products in human, mouse, rat for SLC25A40
Predesigned siRNA for gene silencing in human, mouse, rat SLC25A40

Gene Editing
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Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A40


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
S2540_HUMAN, Q8TBP6: Mitochondrion inner membrane; Multi-pass membrane protein (By similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
mitochondrion5
peroxisome2
plasma membrane2
cytosol1
endoplasmic reticulum1
extracellular1

Gene Ontology (GO): 3 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005739mitochondrion ----
GO:0005743mitochondrial inner membrane IEA--
GO:0016021integral component of membrane IEA--

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(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC25A40
Interactions:

    Search GeneGlobe Interaction Network for SLC25A40

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for SLC25A40 (ENSP000003448314) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
RANBP3ENSP000003414834STRING: ENSP00000341483
--ENSP000003393444STRING: ENSP00000339344
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Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0055085transmembrane transport IEA--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for SLC25A40 (S2540)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for SLC25A40 gene: 
NM_018843.3  

Unigene Cluster for SLC25A40:

Solute carrier family 25, member 40
Hs.208414  [show with all ESTs]
Unigene Representative Sequence: NM_018843
8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000341119(uc003uje.3) ENST00000446236 ENST00000496348 ENST00000429674
ENST00000470328 ENST00000483810 ENST00000444363 ENST00000491499
miRNA
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6 qRT-PCR Assays for microRNAs that regulate SLC25A40:
hsa-miR-23b hsa-miR-130a* hsa-miR-494 hsa-miR-23a hsa-miR-23c hsa-miR-551b*
SwitchGear 3'UTR luciferase reporter plasmidSLC25A40 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for SLC25A40
Predesigned siRNA for gene silencing in human, mouse, rat SLC25A40
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GenScript: all cDNA clones in your preferred vector: SLC25A40 (NM_018843)
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Primer
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OriGene qPCR primer pairs and template standards for SLC25A40
OriGene qSTAR qPCR primer pairs in human, mouse for SLC25A40
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLC25A40
  QuantiTect SYBR Green Assays in human, mouse, rat SLC25A40
  QuantiFast Probe-based Assays in human, mouse, rat SLC25A40

Additional mRNA sequence: 

AF125531.1 AK223020.1 AK290848.1 AL110179.1 BC027322.1 

10 DOTS entries:

DT.100778051  DT.100775582  DT.100817855  DT.455675  DT.121067462  DT.100778050  DT.121067472  DT.91869657 
DT.102831892  DT.91665718 

Selected AceView cDNA sequences (see all 94):

AW057637 AI768857 AW440440 BX509288 BM783026 BX403044 NM_018843 BC027322 
BM461004 AI124670 AA566144 BF109962 CA309341 AA401605 AI867011 AA566141 
AL080033 BX412894 CR610506 AA465546 CD723698 AA721105 BX393358 BQ008206 

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A40    About this scheme

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b
SP1:                    -                                               -                     
SP2:                    -                                                                     
SP3:                                                        -           -                     
SP4:                                                                                          


ECgene alternative splicing isoforms for SLC25A40

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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SLC25A40 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ACACAAAAGT
SLC25A40 Expression
About this image

SLC25A40 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

SLC25A40 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.208414
    Custom PCR Arrays for SLC25A40
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A40

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of eukaryotes.

Orthologs for SLC25A40 gene from Selected species (see all 22)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Slc25a401 , 5 solute carrier family 25, member 401, 5 86.61(n)1
83.33(a)1
  5 (3.43 cM)5
3196531  NM_178766.41  NP_848881.21 
 84228505 
chicken
(Gallus gallus)
Aves SLC25A401 solute carrier family 25, member 40 68.97(n)
61.26(a)
  772037  XM_001235237.3  XP_001235238.3 
lizard
(Anolis carolinensis)
Reptilia SLC25A406
solute carrier family 25, member 40
57(a)
1 ↔ 1
6(19396011-19407370)
tropical clawed frog
(Xenopus tropicalis)
Amphibia MGC761232 hypothetical protein MGC76123 74.47(n)    BC064218.1 
zebrafish
(Danio rerio)
Actinopterygii slc25a401 solute carrier family 25, member 40 63.58(n)
66.36(a)
  436633  NM_001002360.1  NP_001002360.1 
fruit fly
(Drosophila melanogaster)
Insecta Shawn1 Shawn 50.83(n)
48.14(a)
  3772641  NM_001031902.2  NP_001027073.1 
worm
(Caenorhabditis elegans)
Secernentea CELE_C16C10.11 CELE_C16C10.1 54.47(n)
51.1(a)
  175537  NM_065435.4  NP_497836.2 
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MTM11 MTM1 49.56(n)
39.87(a)
  853173   NP_011773.3 
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G463201 AT2G46320 44.69(n)
35.91(a)
  819240  NM_180120.2  NP_850451.1 


ENSEMBL Gene Tree for SLC25A40 (if available)
TreeFam Gene Tree for SLC25A40 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for SLC25A40 gene
SLC25A392  
1 SIMAP similar gene for SLC25A40 using alignment to 3 protein entries:     S2540_HUMAN (see all proteins):
SLC25A39

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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for SLC25A40 (see all 686)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 7 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1809687351,2
--87463805(+) AAACGA/CCTAGG 1 -- int10--------
rs1121041901,2
F--87463833(+) CTTACC/TTTATT 1 -- ut311Minor allele frequency- T:0.50CSA 2
rs1903048001,2
--87464129(+) AAAACA/GTTTTA 1 -- ut310--------
rs1816337481,2
--87464187(+) AAATTC/TAAGGT 1 -- ut310--------
rs21888311,2
C,F,H--87464272(-) TAGTAG/AGAAAG 1 -- ut3110Minor allele frequency- A:0.03NA EA NS 921
rs1476365441,2
--87464380(+) ATAAAC/GACTGC 1 -- ut310--------
rs733938221,2
C,F--87464408(+) AAAAAT/AATATA 1 -- ut312Minor allele frequency- A:0.03WA EA 122
rs1419877301,2
C--87464668(+) GCAATA/CATCTG 1 -- ut310--------
rs1457901291,2
--87464794(+) TCTAAA/GTACTA 1 -- ut310--------
rs171499411,2
C,F--87464844(+) ACATTT/CGCTAC 1 -- ut313Minor allele frequency- C:0.01NA 142

HapMap Linkage Disequilibrium report for SLC25A40 (87462883 - 87505692 bp)

Structural Variations
     Database of Genomic Variants (DGV) 3 variations for SLC25A40:    About this table    
Variant IDTypeSubtypePubMed ID
esv2734777CNV Deletion23290073
nsv464622CNV Gain19166990
nsv888677CNV Gain21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing SLC25A40
DNA2.0 Custom Variant and Variant Library Synthesis for SLC25A40

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 610821    OMIM disorders: --


Find genes that share disorders with SLC25A40           About GenesLikeMe

Genetic Association Database (GAD): SLC25A40
Human Genome Epidemiology (HuGE) Navigator: SLC25A40 (1 document)

Export disorders for SLC25A40 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for SLC25A40 gene, integrated from 10 sources (see all 12):
(articles sorted by number of sources associating them with SLC25A40)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system. (PubMed id 16949250)1, 2, 3 Haitina T.... Fredriksson R. (Genomics 2006)
  2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
  3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
  4. Joint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia. (PubMed id 24268658)1 Rosenthal E.A....Jarvik G.P. (Am. J. Hum. Genet. 2013)
  5. The mitochondrial transporter family SLC25: identification, properties and physiopathology. (PubMed id 23266187)1 Palmieri F. (Mol. Aspects Med. 2013)
  6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
  7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
  9. The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (Nature 2003)
  10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
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  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 55972 HGNC: 29680 AceView: MCFP Ensembl:ENSG00000075303 euGenes: HUgn55972
ECgene: SLC25A40 H-InvDB: SLC25A40

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for SLC25A40 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for SLC25A40 gene:
Search GeneIP for patents involving SLC25A40

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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