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SLC25A4 Gene

protein-coding   GIFtS: 66

GC04P186301
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: PEO3, PEO2, ANT1)
Services    

Aliases &
Descriptions
for SLC25A4

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
AAC1 2
ANT 2
ANT1 2, 3, 5
PEO2 2
PEO3 2, 5
T1 1, 2, 5
Descriptions
ADP,ATP carrier protein 1 3
ADP,ATP carrier protein, heart/skeletal muscle isoform T1 3
ANT 1 3
Adenine nucleotide translocator 1 3
Solute carrier family 25 member 4 3
adenine nucleotide translocator 1 (skeletal muscle) 2
solute carrier family 25 (mitochondrial carrier; adenine
nucleotide translocator), member 4 2
External Ids
HGNC: 109901
Entrez Gene: 2912
UniProtKB: P122353
Ensembl: ENSG000001517297
Search outside databases for aliases for SLC25A4 gene

Previous GC identifers: GC04P187100 GC04P186744 GC04P186648 GC04P186760 GC04P186439

Summaries
for SLC25A4

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ADT1_HUMAN, P12235
Function: Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane

Gene Wiki entry for SLC25A4

Genomic Location
for SLC25A4

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the SLC25A4 gene  

Entrez Gene cytogenetic band: 4q35   Ensembl cytogenetic band:  4q35.1   HGNC cytogenetic band: 4q35

SLC25A4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P186301:     (about GC identifiers)

Start:
 186,301,392 bp from pter
End:
 186,305,419 bp from pter
Size:
 4,028 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000004.10  NT_022792.17  

Proteins
for SLC25A4

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: ADT1_HUMAN, P12235 (See protein sequence)
Recommended Name: ADP/ATP translocase 1  
Size: 298 amino acids; 33064 Da
Subunit: Homodimer. Interacts with HIV-1 Vpr
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Miscellaneous: The transmembrane helices are not perpendicular to the plane of the membrane, but
cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to
the presence of a conserved proline residue (By similarity)

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_001142.2  

    ENSEMBL proteins: 
    ENSP00000281456 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Adenine Nucleotide Translocase 1)
    Human Recombinant Proteins from Abnova (SLC25A4)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    4 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739 mitochondrion TAS10926541
    GO:0005743 mitochondrial inner membrane IEA--
    GO:0005887 integral to plasma membrane TAS2823266
    GO:0016020 membrane IEA--
    About this table

    Antibodies for SLC25A4: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for SLC25A4
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (Adenine Nucleotide Translocase 1), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (SLC25A4)
    Novus Biologicals Antibodies for SLC25A4

    Assays for SLC25A4: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for SLC25A4

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro domains/families:
     IPR001993 Mitochondria_substrate_carrier
     IPR002067 Mit_carrier
     IPR018108 Mitochondrial_sb/sol_carrier
     IPR002113 Aden_trnslctor


       GeneDecks  SLC25A4 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P12235

    ProtoNet protein and cluster: P12235

    2 Blocks protein families:
    IPB002067 Mitochondrial carrier protein signature
    IPB002113 Adenine nucleotide translocator 1 signature


    UniProtKB/Swiss-Prot: ADT1_HUMAN, P12235
    Similarity: Belongs to the mitochondrial carrier family
    Similarity: Contains 3 Solcar repeats

    Gene Function
    for SLC25A4

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (SLC25A4)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (SLC25A4)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001151

                  Applied Biosystems Silencer® siRNAs for SLC25A4

                  Sigma-Aldrich siRNA and siRNA Panels for SLC25A4  
                         Sigma-Aldrich shRNA for SLC25A4  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for SLC25A4
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_001151
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_001151
                                     untagged cDNA clone in CMV expression vector: NM_001151 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_001151

    UniProtKB/Swiss-Prot: ADT1_HUMAN, P12235
    Function: Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane

    5 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Slc25a4):

    cellularhomeostasis/metabolismmusclenormal

    4 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215 transporter activity IEA--
    GO:0005471 ATP:ADP antiporter activity IEA--
    GO:0005488 binding IEA--
    GO:0015207 adenine transmembrane transporter activity TAS2823266
    About this table

    Pathways & Interactions
    for SLC25A4

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Millipore Pathway for SLC25A4
     Apoptosis and survival Regulation of Apoptosis by Mitochondrial Proteins

       GeneDecks  SLC25A4 for the pathways selected above  
    About GeneDecksing

    1 Sigma-Aldrich "Your Favorite Gene" Pathway for  SLC25A4  (Your Favorite Gene powered by Ingenuity) 
     Induction of Apoptosis by HIV1

       GeneDecks  SLC25A4 for the pathways selected above  
    About GeneDecksing

    3 Kegg Pathways  (Kegg details for SLC25A4):
     hsa04020 Calcium signaling pathway
     hsa05012 Parkinson's disease
     hsa05016 Huntington's disease

       GeneDecks  SLC25A4 for the pathways selected above  
    About GeneDecksing
     Gene Network CentralTM Interacting Genes and Proteins Network for  SLC25A4 


    5/22 Interacting proteins for SLC25A4 (ENSP000002814563 P122352) via UniProtKB, MINT, and/or STRING (see all 22 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TNFRSF1BP203332MINT-49409
    PPIFENSP000002251743STRING (score=.993)
    VDAC1ENSP000002653333STRING (score=.992)
    BAXENSP000002932883STRING (score=.986)
    PPIDENSP000003037543STRING (score=.969)
    About this table

    5/7 Gene Ontology (GO) biological process terms (links to tree view) (see all 7 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000002 mitochondrial genome maintenance TAS10926541
    GO:0006091 generation of precursor metabolites and energy TAS2823266
    GO:0006810 transport TAS2823266
    GO:0015866 ADP transport IEA--
    GO:0015867 ATP transport IEA--
    About this table

    Drugs & Compounds
    for SLC25A4

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Enzo Life Sciences drugs & compounds for SLC25A4
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for SLC25A4
    9 Novoseek chemical compound relationships for SLC25A4 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    ptpc 82.69 5 11175349 (2), 18085536 (1), 12022947 (1)
    adp 75.22 36 12543814 (3), 12149099 (2), 19033201 (2), 16107323 (2) (see all 20)
    carboxyatractyloside 73.94 4 10989667 (1), 12488555 (1)
    atp 64.31 33 12543814 (3), 16107323 (3), 1885585 (2), 9714750 (2) (see all 23)
    diamide 42.98 4 12149099 (4)
    calcium 16.91 19 16887100 (5), 9714750 (3), 15061651 (2), 16268121 (1) (see all 7)
    oxygen 15.46 2 19452617 (1), 9789011 (1)
    lipid 0.00 2 16268121 (1), 9789011 (1)
    fatty acid 0.00 2 10899325 (1), 12445829 (1)
    About this table


    Transcripts
    for SLC25A4

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (SLC25A4)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (SLC25A4)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001151

                  Sigma-Aldrich siRNA and siRNA Panels for SLC25A4  
                         Sigma-Aldrich shRNA for SLC25A4  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001151  

    REFSEQ mRNAs for SLC25A4 gene: 

    NM_001151.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001151  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_001151
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_001151
                                     untagged cDNA clone in CMV expression vector: NM_001151 

    Additional cDNA sequence: 

    AB209764.1 AK291902.1 AY494057.1 AY494058.1 BC008664.1 BC043280.2 BC061589.1 BC063643.1 
    CR598134.1 CR611257.1 CR614607.1 CR615898.1 J02966.1 J03593.1 

    12 DOTS entries:

    DT.456149  DT.97858494  DT.95339307  DT.102831901  DT.95182448  DT.75137470  DT.95339305  DT.95339341 
    DT.99997671  DT.100804173  DT.121228132  DT.95260663 

    24/256 AceView cDNA sequences (see all 256 ):

    AI623284 BU624014 CD674171 BU727391 F01810 CR614607 AL582717 CN482512 
    BU626041 AY494058 AW071919 BM704620 AW778868 BM888019 F04281 AI311663 
    CF552890 AA883386 BM689271 AW241654 AI357942 BM694069 D57716 BU752273 

    highest scoring ESTs for SLC25A4:

    AJ572198 BC061589 BC063643 CB852773 CF456516 CF456999 CF552890 AA394025 AA649936 AA855023 

    Unigene Cluster for SLC25A4:

    Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
    Hs.246506  [show with all ESTs]
    Unigene Representative Sequence: AB209764


    GeneLoc Exon Structure

    1 Ensembl transcript including schematic representation:
    ENST00000281456  

    Expression
    for SLC25A4

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    SLC25A4 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for SLC25A4

    1 / 2 / 3

    3 probe-sets matching SLC25A4 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    32822_at2, 3 U95-A 4 1.00 0.95 1.00 1.00 J02966 0.80 0.80 0.80 1

    		202825_at2, 3 U133-A 1 1.00 1.00 -- -- NM_001151 0.40 0.67 0.55 1

    		202825_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  SLC25A4 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: TATTTTGTAT

    SOURCE GeneReport for Unigene cluster: Hs.246506

    Expression variation in blood from EXPOLDB for SLC25A4

    Orthologs
    for SLC25A4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for SLC25A4 gene from 5/13 species (see all 13 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 SLC25A41   -- solute carrier family 25 (mitochondrial carrier; adenine more 90.38(n)
    94.3(a)    		 475630  XM_532844.2  XP_532844.2 
    chimpanzee
    (Pan troglodytes)    		 SLC25A41   -- solute carrier family 25 (mitochondrial carrier; adenine more 97.43(n)
    97.32(a)    		 461632  XM_517556.2  XP_517556.2 
    cow
    (Bos taurus)    		 SLC25A41   -- solute carrier family 25 (mitochondrial carrier; adenine more 92.73(n)
    95.97(a)    		 282478  NM_174658.1  NP_777083.1 
    rat
    (Rattus norvegicus)    		 Slc25a41   -- solute carrier family 25 (mitochondrial carrier; adenine more 91.72(n)
    95.64(a)    		 85333  NM_053515.1  NP_445967.1 
    mouse
    (Mus musculus)    		 Slc25a41, 5 8 (26.00 cM)5
    		 solute carrier family 25 (mitochondrial carrier, adenine more1, 5 91.16(n)1
    95.3(a)1    		 117391  NM_007450.31  NP_031476.21 
     AF2400025  AK0511725  (see all 17)
    About this table        Species with no ortholog for SLC25A4

    ENSEMBL Gene Tree for SLC25A4

    Paralogs
    for SLC25A4

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for SLC25A4 gene
    SLC25A62  SLC25A52  

    SNPs/Variants
    for SLC25A4

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/46 NCBI SNPs in SLC25A4 are shown (see all 46 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 27)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 4 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs100240681,2
    		A,C,F,H186300335(+) TGAGTA/GAAGAG 1 -- ng514Minor allele frequency- G:0.26EU EA WA 418
    rs76605521,2
    		A,C,F,H186305631(+) CCAGCG/ATTACT 1 -- ng3116Minor allele frequency- A:0.09EA NA EU WA 1472
    rs37336521,2
    		F,H186301496(+) CCTGCG/AGGCTG 1 -- ut51 ese33Minor allele frequency- A:0.11EA 1276
    rs125102251,2
    		C,H186305683(+) TCTTAG/AGCACT 1 -- ng314Minor allele frequency- A:0.00EU EA WA 414
    rs10425601,2
    		H186302972(+) ATTGTG/TTGGTG 1 V/L mis1 ese35Minor allele frequency- T:0.00MN EU EA WA 590
    rs344864841,2
    		F186303989(-) TAGGAC/TACCAG 1 V/V syn11Minor allele frequency- T:0.05NA 74
    --
    rs725211641,2
    		--186300271(+) AWAAA-/AACAAT 1 -- ng510--------
    --
    rs681493501,2
    		--186300560(+) TGGAT-/TCTCTCCG 1 -- ng510--------
    --
    rs709625501,2
    		--186299398(+) TCCTT-/CCTT  
                TCTTT     		1 -- ng510--------
    --
    rs664831631,2
    		--186299395(+) TCCTTCCTTC/T 
                CTTTC     		1 -- ng510--------
    About this table

    HapMap Linkage Disequilibrium images for SLC25A4 (up to first 250kb)

    Disorders & Mutations
    for SLC25A4

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 103220   disorders: 157640  

    UniProtKB/Swiss-Prot: ADT1_HUMAN, P12235

  • Defects in SLC25A4 are a cause of progressive external ophthalmoplegia with mitochondrial
    DNA deletions autosomal dominant type 2 (PEOA2) [MIM:609283]. Progressive external ophthalmoplegia
    is characterized by progressive weakness of ocular muscles and levator muscle of the upper eyelid.
    In a minority of cases, it is associated with skeletal myopathy, which predominantly involves
    axial or proximal muscles and which causes abnormal fatigability and even permanent muscle
    weakness. Ragged-red fibers and atrophy are found on muscle biopsy. A large proportion of chronic
    ophthalmoplegias are associated with other symptoms, leading to a multisystemic pattern of this
    disease. Additional symptoms are variable, and may include cataracts, hearing loss, sensory axonal
    neuropathy, ataxia, depression, hypogonadism, and parkinsonism

    • 10 Novoseek disease relationships for SLC25A4 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    chronic progressive external ophthalmoplegia 91.63 6 14557557 (1), 15792871 (1), 16203679 (1), 16303948 (1) (see all 6)
    sengers syndrome 88.99 1 16203679 (1)
    muscular dystrophy facioscapulohumeral 76.05 1 16203679 (1)
    mitochondrial diseases 75.79 1 16203679 (1)
    mitochondrial myopathies 71.95 1 16303948 (1)
    dilated cardiomyopathy 22.93 1 16107323 (1)
    cardiomyopathy 22.60 1 16303948 (1)
    bipolar disorder 4.51 1 12565915 (1)
    tumors 3.72 3 18522758 (3)
    cancer 0.00 3 18522758 (2), 16556444 (1)
    About this table

    Human Gene Mutation Database: SLC25A4
    Human Genome Epidemiology Navigator: SLC25A4 (2 documents)

    Medical News
    for SLC25A4

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for SLC25A4

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/145 PubMed articles for SLC25A4 gene (see all 145 ):

    Search for SLC25A4

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SLC25A4

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 291 HGNC: 10990 AceView: SLC25A4 Ensembl:ENSG00000151729 euGenes: HUgn291
    ECgene: SLC25A4 H-InvDB: SLC25A4

    Other Databases showing SLC25A4

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing SLC25A4

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for SLC25A4 Genetics and Cytogenetics in Oncology and Haematology
    GeneReviewshttp://www.genetests.org/query?gene=SLC25A4

    Licensable Technologies
    for SLC25A4

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for SLC25A4

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for SLC25A4:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for SLC25A4-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for SLC25A4 Antibodies for SLC25A4
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for SLC25A4 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
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     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (SLC25A4)
     Antibodies (SLC25A4)
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