Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SLC25A39 Gene

protein-coding   GIFtS: 50
GCID: GC17M042396

Solute Carrier Family 25, Member 39

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Solute Carrier Family 25, Member 391 2
CGI692 5
Solute Carrier Family 25 Member 392

External Ids:    HGNC: 242791   Entrez Gene: 516292   Ensembl: ENSG000000133067   OMIM: 6108205   UniProtKB: Q9BZJ43   

Export aliases for SLC25A39 gene to outside databases

Previous GC identifers: GC17M039753 GC17M038161


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for SLC25A39 Gene:
SLC25A39 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 (PubMed
16949250)).(supplied by OMIM, Mar 2008)

GeneCards Summary for SLC25A39 Gene:
SLC25A39 (solute carrier family 25, member 39) is a protein-coding gene. An important paralog of this gene is SLC25A40.

UniProtKB/Swiss-Prot: S2539_HUMAN, Q9BZJ4
Function: Required for normal heme biosynthesis (By similarity)

Gene Wiki entry for SLC25A39 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC25A39 gene promoter:
         GR   C/EBPbeta   GR-beta   GR-alpha   ATF   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC25A39 promoter sequence
   Search Chromatin IP Primers for SLC25A39

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC25A39


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q12   Ensembl cytogenetic band:  17q21.31   HGNC cytogenetic band: 17q12

SLC25A39 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A39 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M042396:  view genomic region     (about GC identifiers)

Start:
42,396,993 bp from pter      End:
42,402,238 bp from pter
Size:
5,246 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: S2539_HUMAN, Q9BZJ4 (See protein sequence)
Recommended Name: Solute carrier family 25 member 39  
Size: 359 amino acids; 39249 Da
Sequence caution: Sequence=AAF69618.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A8JZZ2 D3DX51 D3DX54 Q4V9M1 Q9P182 Q9UF66 Q9Y379
Alternative splicing: 2 isoforms:  Q9BZJ4-1   Q9BZJ4-2   

Explore the universe of human proteins at neXtProt for SLC25A39: NX_Q9BZJ4

Explore proteomics data for SLC25A39 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SLC25A39 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001137252.1  NP_057100.1  

    ENSEMBL proteins: 
     ENSP00000225308   ENSP00000366299   ENSP00000467681   ENSP00000466676   ENSP00000467964  
     ENSP00000444540   ENSP00000466615   ENSP00000465182   ENSP00000465554   ENSP00000465594  
     ENSP00000467956   ENSP00000466144  

    SLC25A39 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for SLC25A39
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SLC25A39
    GenScript Custom Purified and Recombinant Proteins Services for SLC25A39
    Novus Biologicals SLC25A39 Protein
    Novus Biologicals SLC25A39 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SLC25A39

     
    Search eBioscience for Proteins for SLC25A39 

    SLC25A39 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SLC25A39
    Novus Biologicals SLC25A39 Antibodies
    Search for Antibodies for SLC25A39 at Abcam
    Cloud-Clone Corp. Antibodies for SLC25A39
    Search ThermoFisher Antibodies for SLC25A39
    LSBio Antibodies in human, mouse, rat for SLC25A39

    SLC25A39 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SLC25A39
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SLC25A39
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SLC25A39
    Cloud-Clone Corp. CLIAs for SLC25A39
    Search eBioscience for ELISAs for SLC25A39 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: CGI-69
    Miscellaneous SLC25 mitochondrial transporters

    2 InterPro protein domains:
     IPR023395 Mt_carrier_dom
     IPR018108 Mitochondrial_sb/sol_carrier

    Graphical View of Domain Structure for InterPro Entry Q9BZJ4

    ProtoNet protein and cluster: Q9BZJ4

    UniProtKB/Swiss-Prot: S2539_HUMAN, Q9BZJ4
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 3 Solcar repeats


    Find genes that share domains with SLC25A39           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S2539_HUMAN, Q9BZJ4
    Function: Required for normal heme biosynthesis (By similarity)

    Phenotypes:
         2 GenomeRNAi human phenotypes for SLC25A39:

     Cell cycle / mitosis defect  Increased cell number in S and 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC25A39
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SLC25A39

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC25A39
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC25A39

    miRNA
    Products:
        
    miRTarBase miRNAs that target SLC25A39:
    hsa-mir-124-3p (MIRT022636), hsa-mir-324-3p (MIRT042872), hsa-mir-16-5p (MIRT031718), hsa-mir-1226-3p (MIRT036523), hsa-mir-7-5p (MIRT025628), hsa-mir-103a-3p (MIRT027062)

    Block miRNA regulation of human, mouse, rat SLC25A39 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate SLC25A39:
    hsa-miR-124 hsa-miR-133a hsa-miR-3120-3p hsa-miR-506 hsa-miR-545 hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmidSLC25A39 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SLC25A39
    Predesigned siRNA for gene silencing in human, mouse, rat SLC25A39

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SLC25A39

    Clone
    Products:
         
    OriGene clones in human, mouse for SLC25A39 (see all 12)
    OriGene ORF clones in mouse, rat for SLC25A39
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SLC25A39 (NM_001143780)
    Sino Biological Human cDNA Clone for SLC25A39
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC25A39
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC25A39

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SLC25A39
    Browse ESI BIO Cell Lines and PureStem Progenitors for SLC25A39 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A39


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    S2539_HUMAN, Q9BZJ4: Mitochondrion inner membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol2
    nucleus2
    peroxisome2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with SLC25A39           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC25A39
    Interactions:

        Search GeneGlobe Interaction Network for SLC25A39

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for SLC25A39 (Q9BZJ43 ENSP000003662994) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PDK4Q166543I2D: score=2 
    PRPF3O433953I2D: score=1 
    RAE1P784063I2D: score=1 
    STK16O757163I2D: score=1 
    UBE2AP494593I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006783heme biosynthetic process IEA--
    GO:0006810transport IEA--
    GO:0055085transmembrane transport ----

    Find genes that share ontologies with SLC25A39           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC25A39 (S2539)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SLC25A39 gene (2 alternative transcripts): 
    NM_001143780.1  NM_016016.2  

    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000225308(uc002igm.2 uc010wiw.1 uc010wix.1) ENST00000591006
    ENST00000377095(uc002ign.2 uc010wiy.1) ENST00000590194 ENST00000586016
    ENST00000592372 ENST00000593166 ENST00000537904 ENST00000588767 ENST00000588315
    ENST00000585695 ENST00000588049 ENST00000585636 ENST00000586633 ENST00000592857
    ENST00000591151 ENST00000585523
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SLC25A39 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate SLC25A39:
    hsa-miR-124 hsa-miR-133a hsa-miR-3120-3p hsa-miR-506 hsa-miR-545 hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmidSLC25A39 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SLC25A39
    Predesigned siRNA for gene silencing in human, mouse, rat SLC25A39
    Clone
    Products:
         
    OriGene clones in human, mouse for SLC25A39 (see all 12)
    OriGene ORF clones in mouse, rat for SLC25A39
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SLC25A39 (NM_001143780)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC25A39
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC25A39
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SLC25A39
    OriGene qSTAR qPCR primer pairs in human, mouse for SLC25A39
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLC25A39
      QuantiTect SYBR Green Assays in human, mouse, rat SLC25A39
      QuantiFast Probe-based Assays in human, mouse, rat SLC25A39

    Selected AceView cDNA sequences (see all 925):

    AA678038 Z40066 BM756744 BM461791 CR596200 CR601587 BU678976 BU683623 
    BQ934841 BF825209 BI258148 T32444 CR600839 BQ923383 AA425801 BM967270 
    Z40856 CR616742 T32379 BQ680563 AA873129 BC011178 CR613206 AI521368 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A39 (see all 24)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c · 3d · 3e · 3f ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d · 6e ^ 7a · 7b ^ 8a · 8b · 8c · 8d · 8e ·
    SP1:                    -     -     -     -     -     -     -     -                       -     -                                                     -     -   
    SP2:                    -     -     -     -     -     -     -     -                       -                                                           -     -   
    SP3:                                                                                      -     -                                                               
    SP4:                    -     -     -     -     -     -     -     -                       -     -                 -     -                             -     -   
    SP5:                    -     -     -     -     -     -     -                             -     -                                                     -     -   

    ExUns: 8f ^ 9a · 9b · 9c · 9d · 9e ^ 10a · 10b · 10c ^ 11 ^ 12 ^ 13a · 13b · 13c
    SP1:  -                                   -                                             
    SP2:  -                                   -                                             
    SP3:                                      -                                             
    SP4:  -                                   -                                             
    SP5:  -                                                                                 


    ECgene alternative splicing isoforms for SLC25A39

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SLC25A39 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTCCAGGAA
    SLC25A39 Expression
    About this image


    SLC25A39 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 13) fully expand
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Neural Tube (Nervous System)
             Telencephalon
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
     
     Colon (Gastrointestinal Tract)
     
     Kidney (Urinary System)
    SLC25A39 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC25A39 Protein Expression

    UniProtKB/Swiss-Prot: S2539_HUMAN, Q9BZJ4
    Tissue specificity: Expressed in many tissues. Abundant in testis and kidney

        Custom PCR Arrays for SLC25A39
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SLC25A39
    OriGene qSTAR qPCR primer pairs in human, mouse for SLC25A39
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLC25A39
    QuantiTect SYBR Green Assays in human, mouse, rat SLC25A39
    QuantiFast Probe-based Assays in human, mouse, rat SLC25A39
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A39

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC25A39 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc25a391 , 5 solute carrier family 25, member 391, 5 85.94(n)1
    88.55(a)1
      11 (66.29 cM)5
    680661  NM_026542.31  NP_080818.11 
     1024029855 
    chicken
    (Gallus gallus)
    Aves SLC25A391 solute carrier family 25, member 39 69.71(n)
    65.24(a)
      427072  XM_004948544.1  XP_004948601.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC25A396
    solute carrier family 25, member 39
    63(a)
    1 ↔ 1
    6(66900372-66931078)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.27272 Xenopus laevis transcribed sequence with weak similarity more 73.79(n)    CF283320.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc637362 hypothetical protein MGC63736 73.75(n)   393458  BC055226.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Shawn6
    CG26166
    (see all 3)
    --
    38(a)
    33(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    X(19505559-19509650)
    3R(3548139-3550140)
    worm
    (Caenorhabditis elegans)
    Secernentea C16C10.16
    Protein C16C10.1 (C16C10.1) mRNA, complete cds
    40(a)
    1 → many
    III(4178724-4181438) WBGene00007622
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MTM1(YGR257C)4 Mitochondrial protein of the mitochondrial carrier more   --   7(1007305-1006205) 853173  NP_011773.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons MTM11 MTM1 45.81(n)
    37.11(a)
      828907  NM_118932.4  NP_567790.1 
    rice
    (Oryza sativa)
    Liliopsida Os08g03868001 Os08g0386800 48.22(n)
    40.88(a)
      4345459  NM_001068245.1  NP_001061710.1 


    ENSEMBL Gene Tree for SLC25A39 (if available)
    TreeFam Gene Tree for SLC25A39 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SLC25A39 gene
    SLC25A402  
    1 SIMAP similar gene for SLC25A39 using alignment to 10 protein entries:     S2539_HUMAN (see all proteins):
    SLC25A40

    Find genes that share paralogs with SLC25A39           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for SLC25A39
    PGOHUM00000239333 PGOHUM00000245161


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SLC25A39 (see all 256)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1396440201,2
    --42396658(+) AGAGAC/TGAGGT 2 -- int10--------
    rs1497408891,2
    C--42396671(+) CACCGC/TGTTGG 2 -- int10--------
    rs1817650221,2
    --42396784(+) CAATTC/TTAACC 2 -- int10--------
    rs126028321,2
    C,F,H--42396896(+) AGGTCC/TTCTTC 2 -- int116Minor allele frequency- T:0.05NS EA NA 2096
    rs1836923311,2
    --42397114(+) CGAAGC/GGGGCA 2 -- ut310--------
    rs770103551,2
    F--42397148(+) TGGGGG/CGTGGG 2 -- ut311Minor allele frequency- C:0.01WA 118
    rs1136190441,2
    F--42397192(+) AGAAGC/TTGTGT 2 -- ut312Minor allele frequency- T:0.50CSA 6
    rs1995779261,2
    --42397322(+) CTGCCA/CTCTCC 2 -- ut310--------
    rs2013152961,2
    --42397375(+) CAGCCG/TCCCAG 4 G syn10--------
    rs1890840661,2
    C--42397386(+) AAGCCA/C/GGTCCT 6 R G W mis10--------

    HapMap Linkage Disequilibrium report for SLC25A39 (42396993 - 42402238 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for SLC25A39:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv2061CNV Insertion18451855
    nsv908275CNV Loss21882294
    nsv510713CNV Loss20534489
    nsv908278CNV Loss21882294
    dgv3175n71CNV Loss21882294
    nsv908270CNV Loss21882294

    Human Gene Mutation Database (HGMD): SLC25A39
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC25A39
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC25A39

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 610820    OMIM disorders: --


    Find genes that share disorders with SLC25A39           About GenesLikeMe

    Genetic Association Database (GAD): SLC25A39
    Human Genome Epidemiology (HuGE) Navigator: SLC25A39 (1 document)

    Export disorders for SLC25A39 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SLC25A39 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with SLC25A39)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    2. Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system. (PubMed id 16949250)1, 3 Haitina T.... Fredriksson R. (Genomics 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Overexpression of the human 2-oxoglutarate carrier lowers mitochondrial membrane potential in HEK-293 cells: contrast with the unique cold-induced mitochondrial carrier CGI-69. (PubMed id 11139402)1, 2 Yu X.X.... Adams S.H. (Biochem. J. 2001)
    6. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    7. Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. (PubMed id 11256614)1, 2 Simpson J.C.... Wiemann S. (EMBO Rep. 2000)
    8. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    9. The mitochondrial transporter family SLC25: identification, properties and physiopathology. (PubMed id 23266187)1 Palmieri F. (Mol. Aspects Med. 2013)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 51629 HGNC: 24279 AceView: CGI-69 Ensembl:ENSG00000013306 euGenes: HUgn51629
    ECgene: SLC25A39 H-InvDB: SLC25A39

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SLC25A39 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SLC25A39 gene:
    Search GeneIP for patents involving SLC25A39

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SLC25A39  
     OriGene qPCR primer pairs and template standards for SLC25A39   OriGene Protein Over-expression Lysate for SLC25A39  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SLC25A39  
     OriGene qSTAR qPCR primer pairs in human, mouse for SLC25A39   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SLC25A39   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SLC25A39   OriGene Custom Protein Services for SLC25A39  

     
     
     Block miRNA regulation of human, mouse, rat SLC25A39 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SLC25A39
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC25A39 Predesigned siRNA for gene silencing in human, mouse, rat SLC25A39
     QuantiFast Probe-based Assays in human, mouse, rat SLC25A39 QuantiTect SYBR Green Assays in human, mouse, rat SLC25A39
     Custom PCR Arrays for SLC25A39 Search Chromatin IP Primers for SLC25A39
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLC25A39  Search GeneGlobe Interaction Network for SLC25A39
     Regulatory tfbs in SLC25A39 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SLC25A39 GenScript cDNA clones with any tag delivered in your preferred vector for SLC25A39
     GenScript Custom Assay Services for SLC25A39 GenScript Custom overexpressing Cell Line Services for SLC25A39
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SLC25A39 (S2539)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for SLC25A39
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SLC25A39 antibodies
     SLC25A39 proteins
     SLC25A39 lysates
     Search for Antibodies for SLC25A39 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for SLC25A39
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SLC25A39
     Antibodies for SLC25A39
     ELISAs for SLC25A39
     CLIAs for SLC25A39



     Browse ESI BIO Cell Lines and PureStem Progenitors for SLC25A39
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A39
     SwitchGear 3'UTR luciferase reporter plasmids for SLC25A39
     SwitchGear Promoter luciferase reporter plasmids for SLC25A39
     Search ThermoFisher Antibodies for SLC25A39
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC25A39
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC25A39
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SLC25A39
     LSBio Antibodies in human, mouse, rat for SLC25A39
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for SLC25A39
      Search eBioscience for proteins for SLC25A39
      Search eBioscience for elisas for SLC25A39
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SLC25A39 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4