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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SLC25A37 Gene

protein-coding GIFtS: 54
GCID: GC08P023386

solute carrier family 25 (mitochondrial iron transporter),...

(Previous names: solute carrier family 25, member 37 )

Explore 6 diseases affiliated with
SLC25A37 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Solute Carrier Family 25 (Mitochondrial Iron Transporter), Member 37¹ ²		PRO1278²
MFRN¹ ² ³		PRO1584²
MSCP¹ ² ³		PRO2217²
MFRN1¹ ²		Mitoferrin¹
Solute Carrier Family 25, Member 37¹ ²		Mitoferrin-1¹
Mitochondrial Iron Transporter 1² ³		Predicted Protein Of HQ2217²
Mitochondrial Solute Carrier Protein² ³		Solute Carrier Family 25 Member 37³
MSC²

External Ids:	HGNC: 29786¹	Entrez Gene: 51312²	Ensembl: ENSG00000147454⁷	OMIM: 610387⁵	UniProtKB: Q9NYZ2³

Export aliases for SLC25A37 gene to outside databases

Previous GC identifers: GC08P023443 GC08P023444 GC08P021931

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC25A37:

SLC25A37 is a solute carrier localized in the mitochondrial inner membrane. It functions as an essential iron importer

for the synthesis of mitochondrial heme and iron-sulfur clusters (summary by Chen et al., 2009 (PubMed

19805291)).(supplied by OMIM, Jan 2011)

UniProtKB/Swiss-Prot: MFRN1_HUMAN, Q9NYZ2

Function: Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby

playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is

then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (By

similarity)

Gene Wiki entry for SLC25A37

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000008.10 NC_018919.1 NT_167187.1

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SLC25A37 gene promoter:
Max1 AML1a MyoD Meis-1b SEF-1 (1) ARP-1 Meis-1a Pax-4a Meis-1 c-Myc
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC25A37 promoter sequence

Search SABiosciences Chromatin IP Primers for SLC25A37

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC25A37

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p21.2 Ensembl cytogenetic band: 8p21.2 HGNC cytogenetic band: 8p21.2

SLC25A37 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A37 gene location

GeneLoc information about chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08P023386: view genomic region (about GC identifiers)

Start:	23,386,318 bp from pter	End:	23,432,976 bp from pter
Size:	46,659 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MFRN1_HUMAN, Q9NYZ2 (See protein sequence)

Recommended Name: Mitoferrin-1

Size: 338 amino acids; 37323 Da

Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein (By similarity)

Sequence caution: Sequence=AAF64141.1; Type=Frameshift; Positions=296; Sequence=CAH10415.1; Type=Erroneous translation;

Note=Wrong choice of CDS;

Secondary accessions: A2RU93 Q53FT7 Q69YJ8 Q969S1 Q9P0J2

Alternative splicing: 3 isoforms: Q9NYZ2-1 Q9NYZ2-2 Q9NYZ2-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC25A37: NX_Q9NYZ2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9NYZ2

SLC25A37 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_057696.2

ENSEMBL proteins:

ENSP00000429200 ENSP00000402782 ENSP00000290075 ENSP00000427726 ENSP00000428066

Reactome Protein details: Q9NYZ2
Human Recombinant Protein Products for SLC25A37:

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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for SLC25A37

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005743	mitochondrial inner membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

SLC25A37 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for SLC25A37

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SLC25A37 for domains About GeneDecksing

2 InterPro domains/families:

IPR023395 Mt_carrier_dom

IPR018108 Mitochondrial_sb/sol_carrier

Graphical View of Domain Structure for InterPro Entry Q9NYZ2

ProtoNet protein and cluster: Q9NYZ2

UniProtKB/Swiss-Prot: MFRN1_HUMAN, Q9NYZ2

Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family

Similarity: Contains 3 Solcar repeats

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: MFRN1_HUMAN, Q9NYZ2

Function: Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby

playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is

then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (By

similarity)

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005381	iron ion transmembrane transporter activity	IEA	--

SLC25A37 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for SLC25A37:

Synthetic lethal with c-Myc af

7 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Slc25a37):

hematopoietic system	homeostasis/metabolism	immune system	integument	liver/biliary system
mortality/aging	no phenotypic analysis

SLC25A37 for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Slc25a37^tm1.2Kapl for SLC25A37

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SLC25A37

miRNA Products:		OriGene 3'-UTR Clone: SLC25A37 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC25A37
		8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC25A37 (see all 12):
		hsa-miR-548am hsa-miR-181c hsa-miR-181a hsa-miR-138-2* hsa-miR-181d hsa-miR-1297 hsa-miR-548x hsa-miR-26a

		SwitchGear 3'UTR luciferase reporter plasmid: SLC25A37 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for SLC25A37
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Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC25A37 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC25A37 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A37

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Mitochondrial Iron-Sulfur Cluster Biogenesis

Mitochondrial Iron-Sulfur Cluster Biogenesis

1.00

Metabolism

Metabolism

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

2 Reactome Pathways for SLC25A37

	Mitochondrial Iron-Sulfur Cluster Biogenesis
	Metabolism

SLC25A37 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SLC25A37

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

5/38 Interacting proteins for SLC25A37 (Q9NYZ2³ ENSP00000290075⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 38)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ABCB7	O75027³, ENSP00000253577⁴	I2D: score=1 STRING: ENSP00000253577
ENSG00000258947	Q13509³	I2D: score=1
TUBB3	Q13509³	I2D: score=1
CDK1	P06493³	I2D: score=5
EEF1B2	P24534³	I2D: score=5

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006810	transport	--	--
GO:0006811	ion transport	--	--
GO:0048250	mitochondrial iron ion transport	IEA	--
GO:0055072	iron ion homeostasis	IEA	--

SLC25A37 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SLC25A37

2 HMDB Compounds for SLC25A37 About this table

Compound	Synonyms	CAS #	PubMed Ids
Heme	(protoporphyrinato)iron (see all 19)	14875-96-8	--
Iron	Armco iron (see all 19)	7439-89-6	--

Search CenterWatch for drugs/clinical trials and news about SLC25A37 / MFRN1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SLC25A37 gene:

NM_016612.2

Unigene Clusters for SLC25A37:

Solute carrier family 25 (mitochondrial iron transporter), member 37

Hs.596025 [show with all ESTs], Hs.658208 [show with all ESTs], Hs.726050 [show with all ESTs]

Unigene Representative Sequences: AF495725, AF116640, AK127666

13 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000519973(uc003xdo.3) ENST00000417331 ENST00000290075 ENST00000518881(uc003xdn.1 uc003xdp.3 uc003xdq.3)

ENST00000518300 ENST00000519192 ENST00000520654 ENST00000523930 ENST00000523883

ENST00000517923 ENST00000520949 ENST00000522164 ENST00000521637

miRNA Products:		OriGene 3'-UTR Clone: SLC25A37 Browse OriGene MicroRNA Expression Plasmids
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		8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC25A37 (see all 12):
		hsa-miR-548am hsa-miR-181c hsa-miR-181a hsa-miR-138-2* hsa-miR-181d hsa-miR-1297 hsa-miR-548x hsa-miR-26a

		SwitchGear 3'UTR luciferase reporter plasmid: SLC25A37 3' UTR sequence

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Additional cDNA sequence:

AF113696.1 AF116630.1 AF155660.1 AF223466.1 AK074708.1 AK075313.1 AK093931.1 AK127666.1

AK223194.1 AK314731.1 AL833186.1 AY032628.1 BC015013.2 BC132799.1 BC132801.1

23 DOTS entries:

DT.452970 DT.449372 DT.100766128 DT.121644617 DT.95306265 DT.121473136 DT.95306262 DT.95306263

DT.99995790 DT.100819463 DT.101961081 DT.100037610 DT.100037612 DT.121473137 DT.121473189 DT.95306250

DT.100765545 DT.100819460 DT.121615475 DT.212879 DT.87017086 DT.91678690 DT.99963359

24/568 AceView cDNA sequences (see all 568):

AF155660 H56071 H73778 AW005811 AA939056 AL833186 N39344 AI203832

AI694653 BU677007 BE550036 AI925217 BU631825 AI167780 AA827913 AI650467

AW614430 BQ181834 AI400741 AI065060 AI261492 H91321 AA424146 CB048958

GeneLoc Exon Structure

5/13 Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A37 (see all 13) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3	^	4a	·	4b	·	4c	·	4d	^	5a	·	5b	^	6a	·	6b	·	6c	·	6d	^	7a	·	7b	^	8a	·	8b	^	9a	·	9b	·	9c	·	9d	·	9e
SP1:																													-		-		-		-		-
SP2:									-		-		-		-		-		-		-		-						-		-		-		-		-
SP3:									-				-		-		-		-		-		-						-		-		-		-		-
SP4:									-		-		-		-		-		-										-		-		-		-		-
SP5:

ECgene alternative splicing isoforms for SLC25A37

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SLC25A37 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACATCCCCT

About this image

SLC25A37 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ progenitor E44 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SLC25A37 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC25A37

SOURCE GeneReport for Unigene clusters: Hs.596025 Hs.658208 Hs.726050

SABiosciences Expression via Pathway-Focused PCR Array including SLC25A37:

Mitochondria in human mouse rat

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A37

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for SLC25A37 gene from 8/30 species (see all 30) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	SLC25A37¹	solute carrier family 25, member 37	74.61(n) 78.15(a)		419530 XM_417682.2 XP_417682.1
lizard (Anolis carolinensis)	Reptilia	SLC25A37⁶	--	69(a)	1 ↔ 1	GL343754.1(118798-138360)
zebrafish (Danio rerio)	Actinopterygii	slc25a37¹	solute carrier family 25, member 37	71.92(n) 74.83(a)		387000 NM_001039971.1 NP_001035060.1
fruit fly (Drosophila melanogaster)	Insecta	mfrn¹	mitoferrin	60.1(n) 55.91(a)		43353 NM_143343.2 NP_651600.1
worm (Caenorhabditis elegans)	Secernentea	mfn-1¹	Protein MFN-1	54.59(n) 56.04(a)		174752 NM_064046.3 NP_496447.1
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	MRS4¹	Mrs4p	47.2(n) 41.96(a)		853926 NP_012978.1
thale cress (Arabidopsis thaliana)	eudicotyledons	AT2G30160¹	Mitochondrial substrate carrier family protein	46.42(n) 41.85(a)		817568 NM_128571.2 NP_180577.1
rice (Oryza sativa)	Liliopsida	Os03g0296800¹	hypothetical protein	50.6(n) 43.48(a)		4332542 NM_001056368.1 NP_001049833.1

ENSEMBL Gene Tree for SLC25A37 (if available)
TreeFam Gene Tree for SLC25A37 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SLC25A37 gene

SLC25A28²

2 SIMAP similar genes for SLC25A37 using alignment to 3 protein entries: MFRN1_HUMAN (see all proteins):

SLC25A28 SLC25A36

SLC25A37 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 8 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs188697593^1,2		--	23384426(+)	`ATAAAA/CTGTAT`	1	--	us2k¹		0	--	--	--	--
rs193276916^1,2		--	23384484(+)	`AAAAAA/GTACAT`	1	--	us2k¹		0	--	--	--	--
rs199827014^1,2	C	--	23384502(+)	`TACAC-/ATATATC`	1	--	us2k¹		0	--	--	--	--
rs4872141^1,2	C,F,A,H	--	23384559(+)	`TATGTG/ATATAT`	1	--	us2k¹		5		NA CSA WA	243
rs4872142^1,2	C,A,H	--	23384611(+)	`ATATTC/GTATAC`	1	--	us2k¹		3		NA WA	240
rs113403787^1,2	C	--	23384620(+)	`ACATAC/TATACT`	1	--	us2k¹		1		WA	2
rs6982144^1,2	C	--	23384791(+)	`CCATGC/TGATTC`	1	--	us2k¹		5		CSA WA NA EA	360
rs143603135^1,2		--	23385047(+)	`TCCTGC/TGTATT`	1	--	us2k¹		0	--	--	--	--
rs185047552^1,2		--	23385049(+)	`CTGTGC/TATTTG`	1	--	us2k¹		0	--	--	--	--
rs76418408^1,2	F	--	23385167(+)	`AAAAAC/TGACCT`	1	--	us2k¹		1		EA	120

HapMap Linkage Disequilibrium report for SLC25A37 (23386318 - 23432976 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 9 variations for SLC25A37
2 CNVs: 100295 62784
7 Indels: 41070 65084 43122 10909 59463 13040 47522

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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SLC25A37 for disorders           About GeneDecksing

OMIM gene information: 610387    OMIM disorders: --

6 diseases for SLC25A37:    About MalaCards

hypochromic anemia citrullinemia intrahepatic cholestasis cholestasis

anemia hypoxia

1 disease from the University of Copenhagen DISEASES database for SLC25A37:

Intrahepatic cholestasis

Human Genome Epidemiology (HuGE) Navigator: SLC25A37 (2 documents)

Export disorders for SLC25A37 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SLC25A37 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with SLC25A37)

Utopia: connect your pdf to the dynamic
world of online information

Mitoferrin is essential for erythroid iron assimilation. (PubMed id 16511496)^{1, 3} Shaw G.C....Paw B.H. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Rapid decrease of RNA level of a novel mouse mitochondria solute carrier protein (Mscp) gene at 4-5 weeks of age. (PubMed id 11845285)^{1, 2} Li Q.-Z.... She J.-X. (2001)
Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)^{1, 2} Hu R.-M.... Chen J.-L. (2000)
Abnormal mitoferrin-1 expression in patients with ery thropoietic protoporphyria. (PubMed id 21627978)¹ Wang Y....Bloomer J.R. (2011)
Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)¹ Hendrickson S.L....O'Brien S.J. (2010)
Abcb10 physically interacts with mitoferrin-1 (Slc25a 37) to enhance its stability and function in the erythroid mitochondria. (PubMed id 19805291)¹ Chen W....Paw B.H. (2009)
Hypoxia induces erythroid-specific 5-aminolevulinate synthase expression in human erythroid cells through transforming growth factor-beta signaling. (PubMed id 19187226)¹ Kaneko K....Shibahara S. (2009)
Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)¹ Abdelmohsen K....Gorospe M. (2009)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 51312	HGNC: 29786	AceView: MSCP	Ensembl:ENSG00000147454	euGenes: HUgn51312
ECgene: SLC25A37	H-InvDB: SLC25A37

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SLC25A37	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SLC25A37 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for SLC25A37 gene:
Search GeneIP for patents involving SLC25A37

GeneCards and IP:
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