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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC25A32 Gene

protein-coding   GIFtS: 55
GCID: GC08M104410

solute carrier family 25 (mitochondrial folate carrier)...

(Previous names: solute carrier family 25, member 32 )
 Explore 6 diseases affiliated with
SLC25A32 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC25A32    

Aliases
for SLC25A32 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 25 (Mitochondrial Folate Carrier) , Member 321 2
MFTC1 2 3
MFT2 3 5
Solute Carrier Family 25, Member 321 2
Mitochondrial Folate Transporter/Carrier2
Solute Carrier Family 25 Member 323

External Ids:    HGNC: 296831   Entrez Gene: 810342   Ensembl: ENSG000001649337   OMIM: 6108155   UniProtKB: Q9H2D13   

Export aliases for SLC25A32 gene to outside databases

Previous GC identifers: GC08M104481 GC08M099611


Summaries
for SLC25A32 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SLC25A32:
Folate metabolism is distributed between the cytosolic and mitochondrial compartments. SLC25A32 is a transporter that
shuttles folates from the cytoplasm into mitochondria (Titus and Moran, 2000 (PubMed 10978331)).(supplied by OMIM, Mar
2008)

UniProtKB/Swiss-Prot: MFTC_HUMAN, Q9H2D1
Function: Transports folate across the inner membranes of mitochondria




Genomic Views
for SLC25A32 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.1  NT_008046.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC25A32 gene promoter:
         Max1   C/EBPalpha   Egr-4   HNF-1A   IRF-2   NRF-2   HNF-1   HSF2   Hlf   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC25A32 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC25A32

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC25A32


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22.3   Ensembl cytogenetic band:  8q22.3   HGNC cytogenetic band: 8q22.3

SLC25A32 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A32 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M104410:  view genomic region     (about GC identifiers)

Start:
 104,410,863 bp from pter      End:
 104,427,468 bp from pter
Size:
 16,606 bases      Orientation:
 minus strand

Proteins
for SLC25A32 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MFTC_HUMAN, Q9H2D1 (See protein sequence)
Recommended Name: Mitochondrial folate transporter/carrier  
Size: 315 amino acids; 35407 Da
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Secondary accessions: Q96JZ6 Q96SU7

Explore the universe of human proteins at neXtProt for SLC25A32: NX_Q9H2D1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H2D1

    • SLC25A32 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_110407.2  
    ENSEMBL proteins: 
     ENSP00000297578   ENSP00000430989   ENSP00000427737   ENSP00000430371   ENSP00000443497  
    Reactome Protein details: Q9H2D1
    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: SLC25A32
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    GenScript Custom Purified and Recombinant Proteins Services for SLC25A32
    Novus Biologicals SLC25A32 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SLC25A32

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane TAS--
    GO:0016021integral to membrane IEA--


    SLC25A32 for ontologies           About GeneDecksing



    SLC25A32 Antibody Products: 
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    Assay Products for SLC25A32: 
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    Uscn ELISAs and CLIAs for SLC25A32

    Protein Domains /
    Families
    for SLC25A32 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC25A32 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR023395 Mt_carrier_dom
     IPR002030 Mit_uncoupling
     IPR018108 Mitochondrial_sb/sol_carrier

    Graphical View of Domain Structure for InterPro Entry Q9H2D1

    ProtoNet protein and cluster: Q9H2D1

    UniProtKB/Swiss-Prot: MFTC_HUMAN, Q9H2D1
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 3 Solcar repeats


    Function
    for SLC25A32 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MFTC_HUMAN, Q9H2D1
    Function: Transports folate across the inner membranes of mitochondria

    miRNA
    Products:            		miRTarBase miRNAs that target SLC25A32:
    hsa-let-7b (MIRT001591)

    OriGene 3'-UTR Clone: SLC25A32
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC25A32
    8/24 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC25A32 (see all 24):
    hsa-miR-4328 hsa-miR-25 hsa-miR-301a hsa-miR-450b-3p hsa-miR-340 hsa-miR-223 hsa-miR-3119 hsa-miR-130b
    SwitchGear 3'UTR luciferase reporter plasmid: SLC25A32 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC25A32 (see all 4)
    OriGene shRNA RFP: SLC25A32
    OriGene siRNA: SLC25A32
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC25A32

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for SLC25A32

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC25A32 (see all 2)
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    GenScript: all cDNA clones in your preferred vector: SLC25A32 (NM_030780)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC25A32
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC25A32 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for SLC25A32
    Search LifeMap BioReagents cell lines for SLC25A32

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A32

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008517folic acid transporter activity NAS10978331


    SLC25A32 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SLC25A32:
     Decreased viability with pacli 


    Pathways & Interactions
    for SLC25A32 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Vitamin B5 (pantothenate) metabolism
    		Metabolism of vitamins and cofactors0.21
    		Metabolism of water-soluble vitamins and cofactors0.21
    2Metabolism
    		Metabolism1.00
    3glycine biosynthesis I
    		Metabolism of folate and pterines0.10

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4        Reactome Pathways for SLC25A32
        Metabolism of folate and pterines
    Metabolism
    Metabolism of vitamins and cofactors
    Metabolism of water-soluble vitamins and cofactors



    SLC25A32 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC25A32

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    4 Interacting proteins for SLC25A32 (Q9H2D13 ENSP000002975784) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HSP90AA1P079003I2D: score=1 
    WDR6Q9NNW53I2D: score=1 
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006766vitamin metabolic process TAS--
    GO:0006767water-soluble vitamin metabolic process TAS--
    GO:0006810transport ----
    GO:0006839mitochondrial transport IEA--
    GO:0015884folic acid transport NAS10978331


    SLC25A32 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC25A32 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC25A32

    1 HMDB Compound for SLC25A32    About this table
    CompoundSynonyms CAS #PubMed Ids
    Folic acidAcifolic (see all 37)59-30-3--

    1 DrugBank Compound for SLC25A32    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Folic AcidFolate (see all 9)59-30-3transportersubstrate17139284 17016423

    Search CenterWatch for drugs/clinical trials and news about SLC25A32 / MFTC 

    Transcripts
    for SLC25A32 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC25A32 gene: 
    NM_030780.3  

    Unigene Cluster for SLC25A32:

    Solute carrier family 25 (mitochondrial folate carrier) , member 32
    Hs.607819  [show with all ESTs]
    Unigene Representative Sequence: NM_030780
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000297578(uc003yll.3 uc011lhr.2) ENST00000521645 ENST00000523256
    ENST00000523866 ENST00000523701 ENST00000543107

    miRNA
    Products:             		 OriGene 3'-UTR Clone: SLC25A32
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC25A32
    8/24 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC25A32 (see all 24):
    hsa-miR-4328 hsa-miR-25 hsa-miR-301a hsa-miR-450b-3p hsa-miR-340 hsa-miR-223 hsa-miR-3119 hsa-miR-130b
    SwitchGear 3'UTR luciferase reporter plasmid: SLC25A32 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC25A32 (see all 4)
    OriGene shRNA RFP: SLC25A32
    OriGene siRNA: SLC25A32
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC25A32
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC25A32 (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC25A32 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SLC25A32 (NM_030780)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC25A32
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC25A32 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC25A32
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC25A32
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC25A32
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC25A32

    Additional cDNA sequence: 

    AF283645.1 AK027531.1 AK027787.1 AK074452.1 AK125492.1 AK300748.1 BC021893.1 

    12 DOTS entries:

    DT.97760546  DT.100717942  DT.309789  DT.100735678  DT.91935355  DT.100813169  DT.452242  DT.121479083 
    DT.40205720  DT.121479260  DT.211585  DT.91642872 

    24/155 AceView cDNA sequences (see all 155):

    BI596954 CD519384 BQ003385 AA373485 AF283645 BQ189556 BX105179 AI754086 
    NM_030780 BM745008 BQ214024 BP353367 AK125733 BM785479 BQ010024 AA437234 
    BQ688177 BP429500 BC021893 CA412829 AA442299 AU280176 AI792141 BM923982 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A32    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8
    SP1:                                                            
    SP2:        -                                                   
    SP3:                                                            
    SP4:                          -                                 


    ECgene alternative splicing isoforms for SLC25A32

    Expression
    for SLC25A32 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC25A32 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAGATGAATG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SLC25A32 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Neural TubeMetencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SLC25A32 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC25A32

    SOURCE GeneReport for Unigene cluster: Hs.607819

    UniProtKB/Swiss-Prot: MFTC_HUMAN, Q9H2D1
    Tissue specificity: Ubiquitous

        SABiosciences Custom PCR Arrays for SLC25A32
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A32

    Orthologs
    for SLC25A32 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC25A32 gene from 9/34 species (see all 34)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SLC25A321 solute carrier family 25, member 32 75.17(n)
    77.52(a)    		   428377  NM_001031506.1  NP_001026677.1 
    lizard
    (Anolis carolinensis)    		 Reptilia SLC25A326
    		 --
    		 73(a)
    		 1 ↔ 1
    		 4(13681613-13693992)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.155502 Xenopus laevis transcribed sequence with weak similarity more 72.59(n)    BJ068351.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc556102 hypothetical protein MGC55610 71.38(n)   393226  BC048057.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG80261 CG8026 56.99(n)
    57.43(a)    		   35941  NM_165664.2  NP_724769.2 
    worm
    (Caenorhabditis elegans)    		 Secernentea K01C8.71 Protein K01C8.7 50.83(n)
    43.26(a)    		   186841  NM_063345.3  NP_495746.1 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes YIA6(YIL006W)4
    FLX11    		 Mitochondrial NAD+ transporter, involved in the transport more4
    Flx1p1    		 47.65(n)1
    35.38(a)1    		   9(344062-345183)4
    8546721  NP_012132.31  8548114 
     NP_012260.14 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons FOLT11 folate transporter 1 51(n)
    46.29(a)    		   836770  NM_126036.3  NP_569032.1 
    rice
    (Oryza sativa)    		 Liliopsida Os03g07347001 hypothetical protein 52.7(n)
    45.95(a)    		   4334018  NM_001057717.1  NP_001051182.1 


    ENSEMBL Gene Tree for SLC25A32 (if available)
    TreeFam Gene Tree for SLC25A32 (if available) 

    Paralogs
    for SLC25A32 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC25A32 gene
    SLC25A172  
    5 SIMAP similar genes for SLC25A32 using alignment to 5 protein entries:     MFTC_HUMAN (see all proteins):
    SLC25A17    SLC25A24    SLC25A29    SLC25A36    SLC25A20

    SLC25A32 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC25A32 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/276 NCBI SNPs in SLC25A32 are shown (see all 276)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 8 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs30982591,2
    		C,F,A,H,--104410420(+) TTCCTG/ATCCTC 1 -- int122Minor allele frequency- A:0.26NS EA NA WA CSA 2350
    rs1502647501,2
    		--104410552(+) TCCCCC/TGTTCT 1 -- int10--------
    rs1902461401,2
    		--104410556(+) CCGTTC/TTGCTG 1 -- int10--------
    rs1489265741,2
    		--104410880(+) AGAGGA/GCAAGA 1 -- ut310--------
    rs1821240501,2
    		--104410883(+) GGACAA/GGAATT 1 -- ut310--------
    rs10611961,2
    		C,F,A,H,--104410928(-) CCATTG/ATTTAA 1 -- ut3122Minor allele frequency- A:0.20NS EA NA CSA WA 2281
    rs125464521,2
    		C,F,H,--104411058(+) TTATAC/AAGCAT 1 -- ut31 ese31Minor allele frequency- A:0.50NA 4
    rs1113980111,2
    		C,--104411077(+) ATGTT-/ATAAG 
                ATATT     		1 -- ut311Minor allele frequency- ATAAG:0.00CSA 2
    rs732879081,2
    		C,--104411239(+) TGCAAC/TAGCAC 1 -- ut311Minor allele frequency- T:0.50WA 2
    rs1382977491,2
    		--104411270(+) TAAAAA/GTACTA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SLC25A32 (104410863 - 104427468 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SLC25A32: --

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    Disorders / Diseases
    for SLC25A32 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC25A32 for disorders           About GeneDecksing

    OMIM gene information: 610815    OMIM disorders: --

    6 diseases for SLC25A32:    About MalaCards
    papillary thyroid carcinoma    follicular adenoma    thyroid carcinoma    adenoma
    thyroiditis    carcinoma

    Human Genome Epidemiology (HuGE) Navigator: SLC25A32 (1 document)

    Export disorders for SLC25A32 gene to outside databases

    Publications
    for SLC25A32 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC25A32 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with SLC25A32)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Retrovirally mediated complementation of the glyB phenotype. Cloning of a human gene encoding the carrier for entry of folates into mitochondria. (PubMed id 10978331)1, 2, 3 Titus S.A. and Moran R.G. (2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    5. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    6. Tetrahydrofolate recognition by the mitochondrial fol ate transporter. (PubMed id 21768094)1 Lawrence S.A....Moran R.G. (2011)
    7. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
    8. Mitochondrial fatty acid transport enzyme deficiency- -implications for in vitro fertilization. (PubMed id 19362304)1 Hull M.L....Feil D. (2009)
    9. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    10. Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)7 Imming P....Meyer A. (2006)

    External Searches for SLC25A32 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SLC25A32 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 81034 HGNC: 29683 AceView: MFTC Ensembl:ENSG00000164933 euGenes: HUgn81034
    ECgene: SLC25A32 H-InvDB: SLC25A32

    Other Databases showing SLC25A32 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC25A32 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC25A32 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC25A32 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC25A32 gene:
    Search GeneIP for patents involving SLC25A32

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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