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Aliases for SLC25A32 Gene

Aliases for SLC25A32 Gene

  • Solute Carrier Family 25 (Mitochondrial Folate Carrier), Member 32 2 3
  • MFT 3 4 6
  • Solute Carrier Family 25, Member 32 2 3
  • MFTC 3 4
  • Solute Carrier Family 25 (Mitochondrial Folate Carrier) , Member 32 3
  • Mitochondrial Folate Transporter/Carrier 3
  • Solute Carrier Family 25 Member 32 4

External Ids for SLC25A32 Gene

Previous GeneCards Identifiers for SLC25A32 Gene

  • GC08M104481
  • GC08M099611
  • GC08M104410

Summaries for SLC25A32 Gene

Entrez Gene Summary for SLC25A32 Gene

  • This gene encodes a member of the P(I/L)W subfamily of mitochondrial carrier family transport proteins. The encoded protein transports folate across the inner mitochondrial membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013]

GeneCards Summary for SLC25A32 Gene

SLC25A32 (Solute Carrier Family 25 (Mitochondrial Folate Carrier), Member 32) is a Protein Coding gene. Among its related pathways are Disease and Metabolism. GO annotations related to this gene include folic acid transporter activity. An important paralog of this gene is SLC25A17.

UniProtKB/Swiss-Prot for SLC25A32 Gene

  • Transports folate across the inner membranes of mitochondria

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC25A32 Gene

Genomics for SLC25A32 Gene

Regulatory Elements for SLC25A32 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SLC25A32 Gene

103,398,635 bp from pter
103,415,335 bp from pter
16,701 bases
Minus strand

Genomic View for SLC25A32 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC25A32 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC25A32 Gene

Proteins for SLC25A32 Gene

  • Protein details for SLC25A32 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Mitochondrial folate transporter/carrier
    Protein Accession:
    Secondary Accessions:
    • Q96JZ6
    • Q96SU7

    Protein attributes for SLC25A32 Gene

    315 amino acids
    Molecular mass:
    35407 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC25A32 Gene

Proteomics data for SLC25A32 Gene at MOPED

Post-translational modifications for SLC25A32 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC25A32 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC25A32 Gene

Domains for SLC25A32 Gene

Gene Families for SLC25A32 Gene

  • SLC :Solute carriers

Protein Domains for SLC25A32 Gene

Suggested Antigen Peptide Sequences for SLC25A32 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q9H2D1
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
  • Contains 3 Solcar repeats.
genes like me logo Genes that share domains with SLC25A32: view

Function for SLC25A32 Gene

Molecular function for SLC25A32 Gene

UniProtKB/Swiss-Prot Function: Transports folate across the inner membranes of mitochondria

Gene Ontology (GO) - Molecular Function for SLC25A32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008517 folic acid transporter activity NAS 10978331
genes like me logo Genes that share ontologies with SLC25A32: view

Phenotypes for SLC25A32 Gene

GenomeRNAi human phenotypes for SLC25A32:
genes like me logo Genes that share phenotypes with SLC25A32: view

Animal Model Products

CRISPR Products

miRNA for SLC25A32 Gene

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SLC25A32 Gene

Localization for SLC25A32 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC25A32 Gene

Mitochondrion inner membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SLC25A32 Gene COMPARTMENTS Subcellular localization image for SLC25A32 gene
Compartment Confidence
mitochondrion 5
cytosol 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for SLC25A32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion --
GO:0005743 mitochondrial inner membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC25A32: view

Pathways for SLC25A32 Gene

genes like me logo Genes that share pathways with SLC25A32: view

Interacting Proteins for SLC25A32 Gene

Gene Ontology (GO) - Biological Process for SLC25A32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006766 vitamin metabolic process TAS --
GO:0006767 water-soluble vitamin metabolic process TAS --
GO:0006810 transport --
GO:0006839 mitochondrial transport IEA --
GO:0015884 folic acid transport NAS 10978331
genes like me logo Genes that share ontologies with SLC25A32: view

Compounds for SLC25A32 Gene

(1) HMDB Compounds for SLC25A32 Gene

Compound Synonyms Cas Number PubMed IDs
Folic acid
  • Acifolic

(1) Drugbank Compounds for SLC25A32 Gene

Compound Synonyms Cas Number Type Actions PubMed IDs
Folic Acid
  • Folate
59-30-3 transporter substrate
genes like me logo Genes that share compounds with SLC25A32: view

Transcripts for SLC25A32 Gene

Unigene Clusters for SLC25A32 Gene

Solute carrier family 25 (mitochondrial folate carrier), member 32:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC25A32

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A32 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8
SP2: -
SP4: -

Relevant External Links for SLC25A32 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC25A32 Gene

mRNA expression in normal human tissues for SLC25A32 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for SLC25A32 Gene

SOURCE GeneReport for Unigene cluster for SLC25A32 Gene Hs.607819

mRNA Expression by UniProt/SwissProt for SLC25A32 Gene

Tissue specificity: Ubiquitous
genes like me logo Genes that share expressions with SLC25A32: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for SLC25A32 Gene

Orthologs for SLC25A32 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SLC25A32 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SLC25A32 35
  • 99.79 (n)
  • 100 (a)
SLC25A32 36
  • 99 (a)
(Bos Taurus)
Mammalia SLC25A32 35
  • 91.35 (n)
  • 93.91 (a)
SLC25A32 36
  • 92 (a)
(Canis familiaris)
Mammalia SLC25A32 35
  • 92.64 (n)
  • 94.31 (a)
SLC25A32 36
  • 94 (a)
(Mus musculus)
Mammalia Slc25a32 35
  • 88.96 (n)
  • 90.76 (a)
Slc25a32 16
Slc25a32 36
  • 89 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 84 (a)
-- 36
  • 70 (a)
(Ornithorhynchus anatinus)
Mammalia SLC25A32 36
  • 86 (a)
(Rattus norvegicus)
Mammalia Slc25a32 35
  • 88.22 (n)
  • 90.13 (a)
(Gallus gallus)
Aves SLC25A32 35
  • 74.92 (n)
  • 76.57 (a)
SLC25A32 36
  • 71 (a)
(Anolis carolinensis)
Reptilia SLC25A32 36
  • 71 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.15550 35
tropical clawed frog
(Silurana tropicalis)
Amphibia slc25a32 35
  • 68.51 (n)
  • 75.57 (a)
(Danio rerio)
Actinopterygii slc25a32a 36
  • 61 (a)
slc25a32b 35
  • 66.01 (n)
  • 70.49 (a)
slc25a32b 36
  • 68 (a)
zgc55610 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007653 35
  • 55.09 (n)
  • 55.84 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8026 35
  • 57.4 (n)
  • 58.28 (a)
CG8026 36
  • 54 (a)
(Caenorhabditis elegans)
Secernentea K01C8.7 35
  • 50.83 (n)
  • 43.26 (a)
K01C8.7 36
  • 41 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AER366W 35
  • 47.52 (n)
  • 37.45 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes FLX1 35
  • 47.53 (n)
  • 35.38 (a)
YEA6 36
  • 30 (a)
YIA6 36
  • 27 (a)
YIA6 38
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F04697g 35
  • 49.45 (n)
  • 38.38 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons FOLT1 35
  • 51 (n)
  • 46.29 (a)
(Oryza sativa)
Liliopsida Os03g0734700 35
  • 52.7 (n)
  • 45.21 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU04180 35
  • 46.81 (n)
  • 39.35 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPBC27B12.09c 35
  • 48.74 (n)
  • 40.91 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.124 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 47 (a)
Species with no ortholog for SLC25A32:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC25A32 Gene

Gene Tree for SLC25A32 (if available)
Gene Tree for SLC25A32 (if available)

Paralogs for SLC25A32 Gene

Paralogs for SLC25A32 Gene

Selected SIMAP similar genes for SLC25A32 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with SLC25A32: view

Variants for SLC25A32 Gene

Sequence variations from dbSNP and Humsavar for SLC25A32 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs1061195 -- 103,399,054(-) ATGCC(A/G)GAATA utr-variant-3-prime, nc-transcript-variant
rs1061196 -- 103,398,700(-) CCATT(A/G)TTTAA utr-variant-3-prime, nc-transcript-variant
rs1865853 -- 103,404,465(+) TGGCA(C/T)GTGTC intron-variant
rs1865854 -- 103,404,557(+) GCCAC(C/T)GCACT intron-variant
rs1865855 -- 103,404,605(+) AAAAA(A/C)ACCAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC25A32 Gene

Variant ID Type Subtype PubMed ID
esv2672690 CNV Deletion 23128226
esv2663185 CNV Deletion 23128226

Relevant External Links for SLC25A32 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC25A32 Gene

Disorders for SLC25A32 Gene

Relevant External Links for SLC25A32

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with SLC25A32: view

No data available for UniProtKB/Swiss-Prot for SLC25A32 Gene

Publications for SLC25A32 Gene

  1. Retrovirally mediated complementation of the glyB phenotype. Cloning of a human gene encoding the carrier for entry of folates into mitochondria. (PMID: 10978331) Titus S.A. … Moran R.G. (J. Biol. Chem. 2000) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 48
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3

Products for SLC25A32 Gene

  • antibodies-online peptides for SLC25A32
  • antibodies-online antibodies for SLC25A32
  • antibodies-online kits for SLC25A32

Sources for SLC25A32 Gene

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