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SLC25A31 Gene

protein-coding   GIFtS: 56
GCID: GC04P128651

Solute Carrier Family 25 (Mitochondrial Carrier; Adenine...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 25 (Mitochondrial Carrier; Adenine Nucleotide
Translocator), Member 311 2
     ADP,ATP Carrier Protein 42 3
AAC42 3 5     ANT 42 3
ANT42 3 5     SFEC35kDa2
Adenine Nucleotide Translocator 42 3     Adenine Nucleotide Translocase 42
Solute Carrier Family 25 Member 312 3     ADP/ATP Translocase 42
Sperm Flagellar Energy Carrier Protein2 3     SFEC3

External Ids:    HGNC: 253191   Entrez Gene: 834472   Ensembl: ENSG000001514757   OMIM: 6107965   UniProtKB: Q9H0C23   

Export aliases for SLC25A31 gene to outside databases

Previous GC identifers: GC04P129010 GC04P128871 GC04P124379


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC25A31 Gene:
Mitochondrial ADP/ATP carriers, such as SLC25A31, are nuclear-coded mitochondrial proteins that catalyze the
exchange of ATP generated in mitochondria by ATP synthase (see MIM 108729) against ADP produced in cytosol by
most energy-consuming reactions (Dolce et al., 2005 (PubMed 15670820)).(supplied by OMIM, Mar 2008)

GeneCards Summary for SLC25A31 Gene:
SLC25A31 (solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31) is a protein-coding gene. Diseases associated with SLC25A31 include mucoepidermoid carcinoma, and huntington's disease. GO annotations related to this gene include transporter activity. An important paralog of this gene is SLC25A6.

UniProtKB/Swiss-Prot: ADT4_HUMAN, Q9H0C2
Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner
membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly
as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility

Gene Wiki entry for SLC25A31 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000004.12  NC_018915.2  NT_016354.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC25A31 gene promoter:
         GR   LHX3b/Lhx3b   GR-beta   CUTL1   E4BP4   AREB6   Nkx6-1   HFH-1   LHX3a/Lhx3a   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC25A31 promoter sequence
   Search Chromatin IP Primers for SLC25A31

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC25A31


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q28.1   Ensembl cytogenetic band:  4q28.1   HGNC cytogenetic band: 4q28

SLC25A31 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A31 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P128651:  view genomic region     (about GC identifiers)

Start:
128,651,533 bp from pter      End:
128,695,448 bp from pter
Size:
43,916 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ADT4_HUMAN, Q9H0C2 (See protein sequence)
Recommended Name: ADP/ATP translocase 4  
Size: 315 amino acids; 35022 Da

Explore the universe of human proteins at neXtProt for SLC25A31: NX_Q9H0C2

Explore proteomics data for SLC25A31 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SLC25A31 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_112581.1  
    ENSEMBL proteins: 
     ENSP00000281154  

    SLC25A31 Human Recombinant Protein Products:

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    Browse Proteins at Cloud-Clone Corp.

    SLC25A31 Antibody Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Mitochondrial adenine nucleotide translocator 4
    Mitochondrial adenine nucleotide translocator family

    4 InterPro protein domains:
     IPR002067 Mit_carrier
     IPR023395 Mt_carrier_dom
     IPR018108 Mitochondrial_sb/sol_carrier
     IPR002113 Aden_trnslctor

    Graphical View of Domain Structure for InterPro Entry Q9H0C2

    ProtoNet protein and cluster: Q9H0C2

    2 Blocks protein domains:
    IPB002067 Mitochondrial carrier protein signature
    IPB002113 Adenine nucleotide translocator 1 signature


    UniProtKB/Swiss-Prot: ADT4_HUMAN, Q9H0C2
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 3 Solcar repeats


    SLC25A31 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ADT4_HUMAN, Q9H0C2
    Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner
    membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly
    as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
         
    SLC25A31 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Slc25a31):
     cellular  endocrine/exocrine gland  reproductive system 

    SLC25A31 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC25A31
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SLC25A31

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC25A31
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC25A31

    miRNA
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    miRTarBase miRNAs that target SLC25A31:
    hsa-mir-335-5p (MIRT018887)

    Block miRNA regulation of human, mouse, rat SLC25A31 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate SLC25A31:
    hsa-miR-3658 hsa-miR-29a* hsa-miR-380
    SwitchGear 3'UTR luciferase reporter plasmidSLC25A31 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SLC25A31

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    GenScript: all cDNA clones in your preferred vector: SLC25A31 (NM_031291)
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A31


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ADT4_HUMAN, Q9H0C2: Mitochondrion inner membrane; Multi-pass membrane protein. Cell projection, cilium,
    flagellum. Note=In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol2
    nucleus1
    peroxisome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005743mitochondrial inner membrane IEA--
    GO:0005929cilium IEA--
    GO:0016021integral component of membrane IEA--

    SLC25A31 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SLC25A31 About    
    See pathways by source

    SuperPathContained pathways About
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Parkinson's disease0.57
    Huntington's disease0.45
    2HTLV-I infection
    HTLV-I infection
    3Calcium signaling pathway
    Calcium signaling pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    4 Kegg Pathways  (Kegg details for SLC25A31):
        Calcium signaling pathway
    Parkinson's disease
    Huntington's disease
    HTLV-I infection


    SLC25A31 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Array including SLC25A31: 
              Mitochondria in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for SLC25A31

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SLC25A31 (Q9H0C23 ENSP000002811544) via UniProtKB, MINT, STRING, and/or I2D (see all 65)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPP4CP605103, ENSP000002793874I2D: score=1 STRING: ENSP00000279387
    DLG4P783523I2D: score=1 
    PPIDENSP000003037544STRING: ENSP00000303754
    UBCENSP000003448184STRING: ENSP00000344818
    CRLS1ENSP000003681404STRING: ENSP00000368140
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0055085transmembrane transport IEA--

    SLC25A31 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC25A31 (ADT4)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SLC25A31 gene: 
    NM_031291.2  

    Unigene Cluster for SLC25A31:

    Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
    Hs.149030  [show with all ESTs]
    Unigene Representative Sequence: NM_031291
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000281154(uc003ifl.3)
    miRNA
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    3 qRT-PCR Assays for microRNAs that regulate SLC25A31:
    hsa-miR-3658 hsa-miR-29a* hsa-miR-380
    SwitchGear 3'UTR luciferase reporter plasmidSLC25A31 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SLC25A31
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat SLC25A31
      QuantiFast Probe-based Assays in human, mouse, rat SLC25A31

    Additional mRNA sequence: 

    AJ863129.1 AL136857.1 AY550240.1 BC022032.2 

    2 DOTS entries:

    DT.40208493  DT.121273768 

    Selected AceView cDNA sequences (see all 31):

    AL136857 BX101152 NM_031291 CD359733 AW593852 BC022032 CD244616 BG719446 
    BU171211 BU568181 AI243338 BM563946 BU567690 BU853653 BI462035 BF980134 
    AW072406 BQ429010 BI520310 BQ438347 BG773445 AI148032 BI521000 BX117656 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A31    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b
    SP1:                                                
    SP2:                    -     -                     


    ECgene alternative splicing isoforms for SLC25A31

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC25A31 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGGAGTTA
    SLC25A31 Expression
    About this image


    SLC25A31 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Gonad
             XY Germ Cells Testis Cord
     
     Testis (Reproductive System)
             XY Germ Cells Testis Cord
     
     Ovary (Reproductive System)
             XX Germ Cells Ovigerous Cord
    SLC25A31 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC25A31 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.149030

    UniProtKB/Swiss-Prot: ADT4_HUMAN, Q9H0C2
    Tissue specificity: Expressed in brain, liver, sperm and testis

        Pathway & Disease-focused RT2 Profiler PCR Array including SLC25A31: 
              Mitochondria in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A31

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC25A31 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc25a311 , 5 solute carrier family 25 (mitochondrial carrier; adenine more1, 5 85.46(n)1
    89.17(a)1
      3 (19.50 cM)5
    733331  NM_178386.31  NP_848473.21 
     407088555 
    lizard
    (Anolis carolinensis)
    Reptilia SLC25A316
    solute carrier family 25 (mitochondrial carrier; a...
    80(a)
    1 ↔ 1
    5(136460176-136473550)
    fruit fly
    (Drosophila melanogaster)
    Insecta sesB6
    Ant26
    Adenine nucleotide translocase 2
    69(a)
    67(a)
    many ↔ many
    many ↔ many
    X(10674926-10680940)
    X(10672987-10680913)
    worm
    (Caenorhabditis elegans)
    Secernentea R07E3.46
    Protein R07E3.4 (R07E3.4) mRNA, complete cds
    43(a)
    many ↔ many
    X(10330596-10331873) WBGene00011105
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PET9(YBL030C)4 Major ADP/ATP carrier of the mitochondrial inner membrane, more   --   2(163997-163041) 852250  NP_009523.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G564501 AT5G56450 55.59(n)
    50.17(a)
      835746  NM_125028.1  NP_200456.1 


    ENSEMBL Gene Tree for SLC25A31 (if available)
    TreeFam Gene Tree for SLC25A31 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC25A31 gene
    SLC25A62  SLC25A42  SLC25A52  
    5 SIMAP similar genes for SLC25A31 using alignment to 1 protein entry:     ADT4_HUMAN:
    SLC25A6    SLC25A4    SLC25A5    SLC25A24    SLC25A16

    SLC25A31 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC25A31 (see all 797)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1419681211,2
    C--128649582(+) CAACTC/GATTTT 1 -- us2k10--------
    rs1895746501,2
    --128649613(+) TGACAA/GCATTC 1 -- us2k10--------
    rs1812241671,2
    --128649762(+) TGTGTG/TGTAAG 1 -- us2k10--------
    rs1850482401,2
    --128649796(+) GAGGTA/GATAAG 1 -- us2k10--------
    rs1469000771,2
    --128649798(+) GGTGAC/TAAGAT 1 -- us2k10--------
    rs1899850451,2
    --128649803(+) TAAGAC/TGGGAT 1 -- us2k10--------
    rs65346371,2
    C,F,A,H--128649890(+) atattA/Cagtga 1 -- us2k126Minor allele frequency- C:0.36NS EA NA WA 2492
    rs1135733971,2
    F--128650252(+) AACAAC/TACTAT 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs1816185791,2
    --128650343(+) TTTTTA/GAATCG 1 -- us2k10--------
    rs1426842021,2
    --128650519(+) ATTTCC/TCCTGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SLC25A31 (128651533 - 128695448 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SLC25A31 (see all 12):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv879923CNV Loss21882294
    nsv437935CNV Loss16468122
    nsv830057CNV Loss17160897
    nsv879916CNV Loss21882294
    nsv290569CNV Loss16902084
    dgv5712n71CNV Loss21882294
    dgv5713n71CNV Loss21882294
    dgv5711n71CNV Loss21882294
    nsv830056CNV Loss17160897
    nsv879925CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC25A31
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610796    OMIM disorders: --

    3 diseases for SLC25A31:    
    About MalaCards
    mucoepidermoid carcinoma    huntington's disease    parkinson's disease

    1 disease from the University of Copenhagen DISEASES database for SLC25A31:
    Mucoepidermoid carcinoma

    SLC25A31 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC25A31
    Human Genome Epidemiology (HuGE) Navigator: SLC25A31 (1 document)

    Export disorders for SLC25A31 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC25A31 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with SLC25A31)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A fourth ADP/ATP carrier isoform in man: identification, bacterial expression, functional characterization and tissue distribution. (PubMed id 15670820)1, 2, 3 Dolce V.... Palmieri F. (FEBS Lett. 2005)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. Compartmentalization of a unique ADP/ATP carrier protein SFEC (sperm flagellar energy carrier, AAC4) with glycolytic enzymes in the fibrous sheath of the human sperm flagellar principal piece. (PubMed id 17137571)1, 2 Kim Y.-H.... Herr J.C. (Dev. Biol. 2007)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    5. The mitochondrial transporter family SLC25: identification, properties and physiopathology. (PubMed id 23266187)1 Palmieri F. (Mol. Aspects Med. 2013)
    6. Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (J Proteomics 2012)
    7. Computational analysis of the transcriptional regulation of the adenine nucleotide translocator isoform 4 gene and its role in spermatozoid glycolytic metabolism. (PubMed id 21827840)1 Dupont P.Y. and Stepien G. (Gene 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Functional expression of human adenine nucleotide translocase 4 in Saccharomyces cerevisiae. (PubMed id 21532989)1 Hamazaki T....Terada N. (PLoS ONE 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83447 HGNC: 25319 AceView: DKFZP434N1235 Ensembl:ENSG00000151475 euGenes: HUgn83447
    ECgene: SLC25A31 Kegg: 83447 H-InvDB: SLC25A31

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC25A31 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC25A31 gene:
    Search GeneIP for patents involving SLC25A31

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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