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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC25A31 Gene

protein-coding   GIFtS: 56
GCID: GC04P128651

Solute Carrier Family 25 (Mitochondrial Carrier; Adenine...

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 25 (Mitochondrial Carrier; Adenine Nucleotide
Translocator), Member 311 2
     ADP,ATP Carrier Protein 42 3
AAC42 3 5     ANT 42 3
ANT42 3 5     SFEC35kDa2
Adenine Nucleotide Translocator 42 3     Adenine Nucleotide Translocase 42
Solute Carrier Family 25 Member 312 3     ADP/ATP Translocase 42
Sperm Flagellar Energy Carrier Protein2 3     SFEC3

External Ids:    HGNC: 253191   Entrez Gene: 834472   Ensembl: ENSG000001514757   OMIM: 6107965   UniProtKB: Q9H0C23   

Export aliases for SLC25A31 gene to outside databases

Previous GC identifers: GC04P129010 GC04P128871 GC04P124379


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC25A31 Gene:
Mitochondrial ADP/ATP carriers, such as SLC25A31, are nuclear-coded mitochondrial proteins that catalyze the
exchange of ATP generated in mitochondria by ATP synthase (see MIM 108729) against ADP produced in cytosol by
most energy-consuming reactions (Dolce et al., 2005 (PubMed 15670820)).(supplied by OMIM, Mar 2008)

GeneCards Summary for SLC25A31 Gene: 
SLC25A31 (solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31) is a protein-coding gene. Diseases associated with SLC25A31 include huntington's disease, and parkinson's disease, and among its related super-pathways are Parkinson's disease. GO annotations related to this gene include transporter activity. An important paralog of this gene is SLC25A6.

UniProtKB/Swiss-Prot: ADT4_HUMAN, Q9H0C2
Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner
membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly
as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility

Gene Wiki entry for SLC25A31 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC25A31 gene promoter:
         GR   LHX3b/Lhx3b   GR-beta   CUTL1   E4BP4   AREB6   Nkx6-1   HFH-1   LHX3a/Lhx3a   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC25A31 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC25A31

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC25A31


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q28.1   Ensembl cytogenetic band:  4q28.1   HGNC cytogenetic band: 4q28

SLC25A31 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A31 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P128651:  view genomic region     (about GC identifiers)

Start:
128,651,533 bp from pter      End:
128,695,448 bp from pter
Size:
43,916 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ADT4_HUMAN, Q9H0C2 (See protein sequence)
Recommended Name: ADP/ATP translocase 4  
Size: 315 amino acids; 35022 Da
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein. Cell projection, cilium,
flagellum. Note=In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region

Explore the universe of human proteins at neXtProt for SLC25A31: NX_Q9H0C2

Explore proteomics data for SLC25A31 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H0C2

  • SLC25A31 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC25A31 Protein Expression
    REFSEQ proteins: NP_112581.1  
    ENSEMBL proteins: 
     ENSP00000281154  

    Human Recombinant Protein Products for SLC25A31: 
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    Novus Biologicals SLC25A31 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005743mitochondrial inner membrane IEA--
    GO:0005929cilium IEA--
    GO:0016021integral to membrane IEA--

    SLC25A31 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Mitochondrial adenine nucleotide translocator 4 
    Mitochondrial adenine nucleotide translocator family

    4 InterPro protein domains:
     IPR002067 Mit_carrier
     IPR023395 Mt_carrier_dom
     IPR018108 Mitochondrial_sb/sol_carrier
     IPR002113 Aden_trnslctor

    Graphical View of Domain Structure for InterPro Entry Q9H0C2

    ProtoNet protein and cluster: Q9H0C2

    2 Blocks protein domains:
    IPB002067 Mitochondrial carrier protein signature
    IPB002113 Adenine nucleotide translocator 1 signature


    UniProtKB/Swiss-Prot: ADT4_HUMAN, Q9H0C2
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 3 Solcar repeats


    SLC25A31 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ADT4_HUMAN, Q9H0C2
    Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner
    membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly
    as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
         
    SLC25A31 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Slc25a31):
     cellular  endocrine/exocrine gland  reproductive system 

    SLC25A31 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC25A31 
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    hsa-miR-3658 hsa-miR-29a* hsa-miR-380
    SwitchGear 3'UTR luciferase reporter plasmidSLC25A31 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC25A31 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Parkinson's disease0.61
    Huntington's disease0.47
    2Calcium signaling pathway
    Calcium signaling pathway
    3HTLV-I infection
    HTLV-I infection

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    4         Kegg Pathways  (Kegg details for SLC25A31):
        Calcium signaling pathway
    Parkinson's disease
    Huntington's disease
    HTLV-I infection


    SLC25A31 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC25A31

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/12 Interacting proteins for SLC25A31 (Q9H0C23 ENSP000002811544) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPP4CP605103, ENSP000002793874I2D: score=1 STRING: ENSP00000279387
    DLG4P783523I2D: score=1 
    PPIDENSP000003037544STRING: ENSP00000303754
    VDAC1ENSP000002653334STRING: ENSP00000265333
    VDAC2ENSP000003616864STRING: ENSP00000361686
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0055085transmembrane transport IEA--

    SLC25A31 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC25A31 (ADT4)

    Search CenterWatch for drugs/clinical trials and news about SLC25A31 / ADT4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC25A31 gene: 
    NM_031291.2  

    Unigene Cluster for SLC25A31:

    Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
    Hs.149030  [show with all ESTs]
    Unigene Representative Sequence: NM_031291
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000281154(uc003ifl.3)

    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC25A31:
    hsa-miR-3658 hsa-miR-29a* hsa-miR-380
    SwitchGear 3'UTR luciferase reporter plasmidSLC25A31 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AJ863129.1 AL136857.1 AY550240.1 BC022032.2 

    2 DOTS entries:

    DT.40208493  DT.121273768 

    24/31 AceView cDNA sequences (see all 31):

    CD244616 AW593852 NM_031291 BX101152 CD359733 AL136857 BC022032 BQ438347 
    AI148032 BG773445 AW072406 BF980134 BG719446 BM563946 BU171211 BI520310 
    BQ429010 AI243338 BU853653 BI462035 BU568181 BU567690 BX117656 BI521000 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A31    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b
    SP1:                                                
    SP2:                    -     -                     


    ECgene alternative splicing isoforms for SLC25A31

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC25A31 expression in normal human tissues (normalized intensities)      SLC25A31 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGGAGTTA
    SLC25A31 Expression
    About this image


    SLC25A31 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             XY Germ Cells Testis Cord
             sperm   
     
     Lung (Respiratory System)    fully expand to see all 2 entries
             visceral organ/lung/right lung   
     
     Gonad
             XY Germ Cells Testis Cord
     
     Ovary (Reproductive System)
             XX Germ Cells Ovigerous Cord
     
     Endothelium (Cardiovascular System)
             blood vessel   

    See SLC25A31 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC25A31

    SOURCE GeneReport for Unigene cluster: Hs.149030

    UniProtKB/Swiss-Prot: ADT4_HUMAN, Q9H0C2
    Tissue specificity: Expressed in brain, liver, sperm and testis

        SABiosciences Expression via Pathway-Focused PCR Array including SLC25A31: 
              Mitochondria in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A31

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC25A31 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc25a311 , 5 solute carrier family 25 (mitochondrial carrier; adenine more1, 5 85.46(n)1
    89.17(a)1
      3 (19.50 cM)5
    733331  NM_178386.31  NP_848473.21 
     407088555 
    lizard
    (Anolis carolinensis)
    Reptilia SLC25A316
    Uncharacterized protein
    79(a)
    1 ↔ 1
    5(136460176-136473550)
    fruit fly
    (Drosophila melanogaster)
    Insecta sesB6
    Ant26
    Adenine nucleotide translocase 2
    69(a)
    66(a)
    1 ↔ many
    possible ortholog
    X(10674926-10680940)
    X(10672987-10680913)
    worm
    (Caenorhabditis elegans)
    Secernentea ant-1.46
    ant-1.16
    (see all 7)
    Protein ANT-1.1, isoform a
    (see all 7)
    65(a)
    65(a)
    (see all 7)
    possible ortholog
    possible ortholog
    (see all 7)
    IV(8459222-8460277)
    III(13463163-13464657)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PET9(YBL030C)4 Major ADP/ATP carrier of the mitochondrial inner membrane, more   --   2(163997-163041) 852250  NP_009523.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ER-ANT11 endoplasmic reticulum-adenine nucleotide transporter more 54.46(n)
    51.06(a)
      831606  NM_121746.3  NP_568345.1 
    rice
    (Oryza sativa)
    Liliopsida Os11g06613001 hypothetical protein 54.73(n)
    50(a)
      4351065  NM_001074941.1  NP_001068409.1 


    ENSEMBL Gene Tree for SLC25A31 (if available)
    TreeFam Gene Tree for SLC25A31 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC25A31 gene
    SLC25A62  SLC25A42  SLC25A52  
    5 SIMAP similar genes for SLC25A31 using alignment to 1 protein entry:     ADT4_HUMAN:
    SLC25A6    SLC25A4    SLC25A5    SLC25A24    SLC25A16

    SLC25A31 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/797 SNPs in SLC25A31 are shown (see all 797)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1419681211,2
    C--128649582(+) CAACTC/GATTTT 1 -- us2k10--------
    rs1895746501,2
    --128649613(+) TGACAA/GCATTC 1 -- us2k10--------
    rs1812241671,2
    --128649762(+) TGTGTG/TGTAAG 1 -- us2k10--------
    rs1850482401,2
    --128649796(+) GAGGTA/GATAAG 1 -- us2k10--------
    rs1469000771,2
    --128649798(+) GGTGAC/TAAGAT 1 -- us2k10--------
    rs1899850451,2
    --128649803(+) TAAGAC/TGGGAT 1 -- us2k10--------
    rs65346371,2
    C,F,A,H--128649890(+) atattA/Cagtga 1 -- us2k126Minor allele frequency- C:0.36NS EA NA WA 2492
    rs1135733971,2
    F--128650252(+) AACAAC/TACTAT 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs1816185791,2
    --128650343(+) TTTTTA/GAATCG 1 -- us2k10--------
    rs1426842021,2
    --128650519(+) ATTTCC/TCCTGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SLC25A31 (128651533 - 128695448 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/12 variations for SLC25A31 (see all 12):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv879923CNV Loss21882294
    nsv437935CNV Loss16468122
    nsv830057CNV Loss17160897
    nsv879916CNV Loss21882294
    nsv290569CNV Loss16902084
    dgv5712n71CNV Loss21882294
    dgv5713n71CNV Loss21882294
    dgv5711n71CNV Loss21882294
    nsv830056CNV Loss17160897
    nsv879925CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610796    OMIM disorders: --

    2 diseases for SLC25A31:    About MalaCards
    huntington's disease    parkinson's disease

    1 disease from the University of Copenhagen DISEASES database for SLC25A31:
    Mucoepidermoid carcinoma

    SLC25A31 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): SLC25A31
    Human Genome Epidemiology (HuGE) Navigator: SLC25A31 (1 document)

    Export disorders for SLC25A31 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC25A31 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with SLC25A31)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A fourth ADP/ATP carrier isoform in man: identification, bacterial expression, functional characterization and tissue distribution. (PubMed id 15670820)1, 2, 3 Dolce V.... Palmieri F. (2005)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. Compartmentalization of a unique ADP/ATP carrier protein SFEC (sperm flagellar energy carrier, AAC4) with glycolytic enzymes in the fibrous sheath of the human sperm flagellar principal piece. (PubMed id 17137571)1, 2 Kim Y.-H.... Herr J.C. (2007)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    5. The mitochondrial transporter family SLC25: identifica tion, properties and physiopathology. (PubMed id 23266187)1 Palmieri F. (2013)
    6. Computational analysis of the transcriptional regulat ion of the adenine nucleotide translocator isoform 4 gene and its role in sperm atozoid glycolytic metabolism. (PubMed id 21827840)1 Dupont P.Y. and Stepien G. (2011)
    7. Integrative analysis of the ubiquitin proteome isolat ed using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Functional expression of human adenine nucleotide tra nslocase 4 in Saccharomyces cerevisiae. (PubMed id 21532989)1 Hamazaki T....Terada N. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83447 HGNC: 25319 AceView: DKFZP434N1235 Ensembl:ENSG00000151475 euGenes: HUgn83447
    ECgene: SLC25A31 Kegg: 83447 H-InvDB: SLC25A31

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC25A31 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC25A31 gene:
    Search GeneIP for patents involving SLC25A31

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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