Aliases for SLC25A3 Gene
External Ids for SLC25A3 Gene
Previous HGNC Symbols for SLC25A3 Gene
Previous GeneCards Identifiers for SLC25A3 Gene
The protein encoded by this gene catalyzes the transport of phosphate into the mitochondrial matrix, either by proton cotransport or in exchange for hydroxyl ions. The protein contains three related segments arranged in tandem which are related to those found in other characterized members of the mitochondrial carrier family. Both the N-terminal and C-terminal regions of this protein protrude toward the cytosol. Multiple alternatively spliced transcript variants have been isolated. [provided by RefSeq, Jul 2008]
GeneCards Summary for SLC25A3 Gene
SLC25A3 (Solute Carrier Family 25 Member 3) is a Protein Coding gene. Diseases associated with SLC25A3 include Mitochondrial Phosphate Carrier Deficiency and Alternating Hemiplegia Of Childhood. Among its related pathways are C-MYB transcription factor network. GO annotations related to this gene include protein complex binding and phosphate ion carrier activity.
UniProtKB/Swiss-Prot for SLC25A3 Gene
Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP).