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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC25A28 Gene

protein-coding   GIFtS: 56
GCID: GC10M101360

Solute Carrier Family 25 (Mitochondrial Iron Transporter),...

(Previous names: solute carrier family 25, member 28)
Alzheimer's & Parkinson's Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 25 (Mitochondrial Iron Transporter), Member
281 2
     hMRS3/42 3
Solute Carrier Family 25, Member 281 2     MRS4L2 5
Mitoferrin 21 2     Mitochondrial RNA Splicing Protein 3/42
Mitochondrial Iron Transporter 22 3     mitoferrin-22
Mitochondrial RNA-Splicing Protein 3/4 Homolog2 3     Putative Mitochondrial Solute Carrier2
MFRN22 3     Solute Carrier Family 25 Member 283
MRS3/42 3     NPD0165

External Ids:    HGNC: 234721   Entrez Gene: 818942   Ensembl: ENSG000001552877   OMIM: 6097675   UniProtKB: Q96A463   

Export aliases for SLC25A28 gene to outside databases

Previous GC identifers: GC10M101034 GC10M094997


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SLC25A28 Gene: 
SLC25A28 (solute carrier family 25 (mitochondrial iron transporter), member 28) is a protein-coding gene. Diseases associated with SLC25A28 include hypochromic anemia, and friedreich ataxia, and among its related super-pathways are Metabolic pathways and Electron Transport from NADPH to Ferredoxin. An important paralog of this gene is SLC25A37.

UniProtKB/Swiss-Prot: MFRN2_HUMAN, Q96A46
Function: Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of
hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria,
presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into
protoprophyrin IX to make heme (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC25A28 gene promoter:
         STAT5A   Nkx2-5   E4BP4   Egr-4   c-Ets-1   CREB   USF-1   HSF2   deltaCREB   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC25A28 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC25A28

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC25A28


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.2   Ensembl cytogenetic band:  10q24.2   HGNC cytogenetic band: 10q24.2

SLC25A28 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A28 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M101360:  view genomic region     (about GC identifiers)

Start:
101,370,275 bp from pter      End:
101,380,366 bp from pter
Size:
10,092 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MFRN2_HUMAN, Q96A46 (See protein sequence)
Recommended Name: Mitoferrin-2  
Size: 364 amino acids; 39272 Da
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein. Note=Isoform 1 and isoform 2 are
both localized in the mitochondrion
Sequence caution: Sequence=AAH47312.1; Type=Erroneous initiation; Sequence=CAI16900.1; Type=Erroneous gene model
prediction;
Secondary accessions: Q4VBZ0 Q5T777 Q86VX5 Q969G8 Q9H2J3
Alternative splicing: 3 isoforms:  Q96A46-1   Q96A46-2   Q96A46-3   

Explore the universe of human proteins at neXtProt for SLC25A28: NX_Q96A46

Explore proteomics data for SLC25A28 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96A46

  • SLC25A28 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC25A28 Protein Expression
    REFSEQ proteins: NP_112489.3  
    ENSEMBL proteins: 
     ENSP00000399102   ENSP00000359526  
    Reactome Protein details: Q96A46
    Human Recombinant Protein Products for SLC25A28: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SLC25A28 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane IEA--
    GO:0016021integral to membrane IEA--

    SLC25A28 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Mitoferrin2 
    Miscellaneous SLC25 mitochondrial transporters

    2 InterPro protein domains:
     IPR023395 Mt_carrier_dom
     IPR018108 Mitochondrial_sb/sol_carrier

    Graphical View of Domain Structure for InterPro Entry Q96A46

    ProtoNet protein and cluster: Q96A46

    UniProtKB/Swiss-Prot: MFRN2_HUMAN, Q96A46
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 3 Solcar repeats


    SLC25A28 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MFRN2_HUMAN, Q96A46
    Function: Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of
    hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria,
    presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into
    protoprophyrin IX to make heme (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for SLC25A28:

     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC25A28 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC25A28 
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    hsa-miR-558 hsa-miR-3119 hsa-miR-2278 hsa-miR-212 hsa-miR-3914 hsa-miR-132
    SwitchGear 3'UTR luciferase reporter plasmidSLC25A28 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC25A28 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolism0.40
    2Mitochondrial Iron-Sulfur Cluster Biogenesis
    Mitochondrial Iron-Sulfur Cluster Biogenesis0.33

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2        Reactome Pathways for SLC25A28
        Mitochondrial Iron-Sulfur Cluster Biogenesis
    Metabolism



    SLC25A28 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC25A28

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for SLC25A28 (ENSP000003595264) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HDAC9ENSP000004086174STRING: ENSP00000408617
    FXNENSP000003664824STRING: ENSP00000366482
    ABCB7ENSP000002535774STRING: ENSP00000253577
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport IEA--
    GO:0044281small molecule metabolic process TAS--
    GO:0055072iron ion homeostasis IEA--

    SLC25A28 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC25A28 (MFRN2)

    2 HMDB Compounds for SLC25A28    About this table
    CompoundSynonyms CAS #PubMed Ids
    Heme(protoporphyrinato)iron (see all 19)14875-96-8--
    IronArmco iron (see all 19)7439-89-6--

    Search CenterWatch for drugs/clinical trials and news about SLC25A28 / MFRN2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC25A28 gene: 
    NM_031212.3  

    Unigene Cluster for SLC25A28:

    Solute carrier family 25 (mitochondrial iron transporter), member 28
    Hs.403790  [show with all ESTs]
    Unigene Representative Sequence: AF327403
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000434701 ENST00000370495(uc001kpx.2) ENST00000496035 ENST00000479722


    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC25A28:
    hsa-miR-558 hsa-miR-3119 hsa-miR-2278 hsa-miR-212 hsa-miR-3914 hsa-miR-132
    SwitchGear 3'UTR luciferase reporter plasmidSLC25A28 3' UTR sequence
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    Additional mRNA sequence: 

    AF267854.1 AF327402.1 AF327403.1 AJ303077.1 AJ303078.1 AK056782.1 AL831943.1 BC015951.1 
    BC047312.1 BC058937.1 BC064541.1 BC076399.1 BC094821.1 

    9 DOTS entries:

    DT.92425745  DT.100808441  DT.216859  DT.100679750  DT.95104988  DT.95104989  DT.75104488  DT.100808427 
    DT.91720495 

    24/93 AceView cDNA sequences (see all 93):

    CR601821 BC058937 BQ673420 CR605062 BC064541 BC076399 BI827322 F19229 
    BX282582 CR590395 AA632252 BC047312 BM662505 AA872576 AJ303077 BQ671641 
    BU734587 BM843278 AF327402 AI370724 BF515180 BG290483 CR591608 AA314176 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A28    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b ^ 5a · 5b · 5c · 5d
    SP1:        -                 -     -     -                                 
    SP2:                    -     -     -     -                                 
    SP3:                          -     -     -                                 
    SP4:                                -                                       
    SP5:                                      -                                 


    ECgene alternative splicing isoforms for SLC25A28

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC25A28 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCTGTGTAT
    SLC25A28 Expression
    About this image


    See SLC25A28 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC25A28

    SOURCE GeneReport for Unigene cluster: Hs.403790

    UniProtKB/Swiss-Prot: MFRN2_HUMAN, Q96A46
    Tissue specificity: Ubiquitous. Expressed in placenta, lung, kidney, pancreas, liver, brain, skeletal muscle and
    heart

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC25A28 gene from 8/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc25a281 , 5 solute carrier family 25, member 281, 5 92.4(n)1
    97.53(a)1
      19 (36.67 cM)5
    2466961  NM_145156.11  NP_660138.11 
     436638225 
    chicken
    (Gallus gallus)
    Aves SLC25A281 solute carrier family 25, member 28 78.21(n)
    82.27(a)
      423832  XM_421702.3  XP_421702.3 
    lizard
    (Anolis carolinensis)
    Reptilia SLC25A286
    Uncharacterized protein
    85(a)
    1 ↔ 1
    3(38383922-38387264)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.287562 Xenopus laevis transcribed sequence with weak similarity more 80.38(n)    BX854445.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc48b022 Danio rerio cDNA clone MGC64212 IMAGE6799180, complete more 77.09(n)    BC054641.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mfrn6
    mitoferrin
    40(a)
    1 → many
    3R(23768511-23773731)
    worm
    (Caenorhabditis elegans)
    Secernentea mfn-16
    Mitoferrin
    50(a)
    1 → many
    II(11470010-11472035)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MRS4(YKR052C)4 Iron transporter that mediates Fe2+ transport across more   --   11(533464-532550) 853926  NP_012978.1 


    ENSEMBL Gene Tree for SLC25A28 (if available)
    TreeFam Gene Tree for SLC25A28 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC25A28 gene
    SLC25A372  
    1 SIMAP similar gene for SLC25A28 using alignment to 1 protein entry:     MFRN2_HUMAN:
    SLC25A37

    SLC25A28 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/202 SNPs in SLC25A28 are shown (see all 202)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2006833431,2
    Cuntested1101373645(+) ATAGCA/GGGCAG 2 R C mis10--------
    rs1881239661,2
    --101369981(+) GGCAGA/GGCTGC 1 -- int10--------
    rs1901903911,2
    --101369991(+) CGAATC/TAGAGC 1 -- int10--------
    rs22974461,2
    C,F,A,H--101370015(+) TTCTGT/CGCTGC 1 -- int123Minor allele frequency- C:0.42NA NS EA WA CSA 2124
    rs1463709791,2
    C--101370020(+) TGCTG-/CGCTAC
            
    CGCCC
    1 -- int10--------
    rs1486000461,2
    --101370333(+) CCTCTA/GTAACA 1 -- ut310--------
    rs1821505921,2
    C--101370541(+) TCCAGG/TAGACA 1 -- ut310--------
    rs788347181,2
    C--101370694(+) AGGGGA/GTCTGG 2 T I mis10--------
    rs2013017531,2
    C,F--101370828(+) TCCTGG/AGTGTT 2 /T syn11Minor allele frequency- A:0.00EU 1323
    rs1998731231,2
    C--101370852(+) CAAACG/ATCCAG 2 /D syn11Minor allele frequency- A:0.00EU 1323

    HapMap Linkage Disequilibrium report for SLC25A28 (101370275 - 101380366 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SLC25A28:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv7515CNV Insertion18451855
    nsv831958CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609767    OMIM disorders: --

    7 diseases for SLC25A28:    About MalaCards
    hypochromic anemia    friedreich ataxia    ataxia    anemia
    crohn's disease    retinitis    alzheimer's disease

    2 diseases from the University of Copenhagen DISEASES database for SLC25A28:
    Hypochromic anemia     Friedreich ataxia

    SLC25A28 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): SLC25A28
    Human Genome Epidemiology (HuGE) Navigator: SLC25A28 (2 documents)

    Export disorders for SLC25A28 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC25A28 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with SLC25A28)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of a novel human putative mitochondrial transporter homologous to the yeast mitochondrial RNA splicing proteins 3 and 4. (PubMed id 11297739)1, 2, 3 Li F.-Y.... Suomalainen A. (2001)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    6. Mitoferrin-2-dependent mitochondrial iron uptake sensi tizes human head and neck squamous carcinoma cells to photodynamic therapy. (PubMed id 23135267)1 Hung H.I....Nieminen A.L. (2013)
    7. Genetic determinants of plasma b_2-glycoprotein I leve ls: a genome-wide association study in extended pedigrees from Spain. (PubMed id 23279374)1 Athanasiadis G....Soria J.M. (2013)
    8. The mitochondrial transporter family SLC25: identifica tion, properties and physiopathology. (PubMed id 23266187)1 Palmieri F. (2013)
    9. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. (PubMed id 22412388)1 Kenny E.E....Peter I. (2012)
    10. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 81894 HGNC: 23472 AceView: SLC25A28 Ensembl:ENSG00000155287 euGenes: HUgn81894
    ECgene: SLC25A28 H-InvDB: SLC25A28

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC25A28 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC25A28 gene:
    Search GeneIP for patents involving SLC25A28

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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