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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC25A24 Gene

protein-coding   GIFtS: 54
GCID: GC01M108677

Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier),
Member 241 2
     Calcium-Binding Mitochondrial Carrier Protein SCaMC-12
Mitochondrial ATP-Mg/Pi Carrier Protein 12 3     Calcium-Binding Transporter2
Mitochondrial Ca(2+)-Dependent Solute Carrier Protein 12 3     Short Calcium-Binding Mitochondrial Carrier 12
Small Calcium-Binding Mitochondrial Carrier Protein 12 3     MCSC13
APC12 3     SCAMC13
SCAMC-12     Solute Carrier Family 25 Member 243

External Ids:    HGNC: 206621   Entrez Gene: 299572   Ensembl: ENSG000000854917   OMIM: 6087445   UniProtKB: Q6NUK13   

Export aliases for SLC25A24 gene to outside databases

Previous GC identifers: GC01M108033 GC01M108389 GC01M106625


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC25A24 Gene:
This gene encodes a carrier protein that transports ATP-Mg exchanging it for phosphate. Multiple transcript
variants encoding different isoforms have been found for this gene. (provided by RefSeq, May 2012)

GeneCards Summary for SLC25A24 Gene: 
SLC25A24 (solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24) is a protein-coding gene. Diseases associated with SLC25A24 include night blindness, and blindness. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is SLC25A23.

UniProtKB/Swiss-Prot: SCMC1_HUMAN, Q6NUK1
Function: Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites,
nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that
mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine
nucleotides into or from the mitochondria




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC25A24 gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   oct-B3   oct-B2   FOXL1   POU2F2   POU2F2C   POU2F1   POU2F1a   POU2F2B   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC25A24 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC25A24

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC25A24


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p13.3   Ensembl cytogenetic band:  1p13.3   HGNC cytogenetic band: 1p13.2

SLC25A24 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A24 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M108677:  view genomic region     (about GC identifiers)

Start:
108,676,658 bp from pter      End:
108,743,471 bp from pter
Size:
66,814 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SCMC1_HUMAN, Q6NUK1 (See protein sequence)
Recommended Name: Calcium-binding mitochondrial carrier protein SCaMC-1  
Size: 477 amino acids; 53354 Da
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAF28888.1; Type=Frameshift; Positions=418, 464; Sequence=CAI13622.1; Type=Erroneous
gene model prediction; Sequence=CAI14512.1; Type=Erroneous gene model prediction;
Secondary accessions: B7ZAI9 Q5T331 Q5T485 Q6PJJ9 Q705K4 Q9P129
Alternative splicing: 2 isoforms:  Q6NUK1-1   Q6NUK1-2   

Explore the universe of human proteins at neXtProt for SLC25A24: NX_Q6NUK1

Explore proteomics data for SLC25A24 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6NUK1

  • SLC25A24 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC25A24 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_037518.3  NP_998816.1  

    ENSEMBL proteins: 
     ENSP00000457733   ENSP00000264128   ENSP00000359058   ENSP00000454393  

    Human Recombinant Protein Products for SLC25A24: 
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    Novus Biologicals SLC25A24 Proteins
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SLC25A24 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane IEA--
    GO:0016021integral to membrane IEA--

    SLC25A24 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers
    EFHAND: EF-hand domain containing

    IUPHAR Guide to PHARMACOLOGY protein family classification: Mitochondrial phosphate carrier 1 
    Miscellaneous SLC25 mitochondrial transporters

    5/7 InterPro protein domains (see all 7):
     IPR018247 EF_Hand_1_Ca_BS
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_dom
     IPR002067 Mit_carrier
     IPR023395 Mt_carrier_dom

    Graphical View of Domain Structure for InterPro Entry Q6NUK1

    ProtoNet protein and cluster: Q6NUK1

    1 Blocks protein domain: IPB002067 Mitochondrial carrier protein signature

    UniProtKB/Swiss-Prot: SCMC1_HUMAN, Q6NUK1
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 4 EF-hand domains
    Similarity: Contains 3 Solcar repeats


    SLC25A24 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SCMC1_HUMAN, Q6NUK1
    Function: Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites,
    nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that
    mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine
    nucleotides into or from the mitochondria
    Biophysicochemical properties: Kinetic parameters: KM=0.97 mM for AMP; KM=0.3 mM for ADP; KM=0.33 mM for ATP;
    KM=0.2 mM for ATP-Mg; KM=1.64 mM for Pi; Vmax=337 umol/min/g enzyme with AMP as substrate; Vmax=345 umol/min/g
    enzyme with ADP as substrate; Vmax=320 umol/min/g enzyme with ATP as substrate; Vmax=365 umol/min/g enzyme with
    ATP-Mg as substrate; Vmax=380 umol/min/g enzyme with Pi as substrate;

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
         
    SLC25A24 for ontologies           About GeneDecksing


    Animal Models:
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC25A24 
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    miRNA
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    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC25A24 (see all 18):
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    SwitchGear 3'UTR luciferase reporter plasmidSLC25A24 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC25A24

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5/6 Interacting proteins for SLC25A24 (Q6NUK12 ENSP000002641284) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ANAPC4Q9UJX52MINT-8413231 MINT-8413062
    ANAPC7Q9UJX32MINT-8413231 MINT-8413062
    BUB1BO605662MINT-8413231 MINT-8413062
    NEK2P519552MINT-8413062
    NTNG1ENSP000003590854STRING: ENSP00000359085
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0055085transmembrane transport IEA--

    SLC25A24 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC25A24 (SCMC1)

    1 HMDB Compound for SLC25A24    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about SLC25A24 / SCMC1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC25A24 gene (2 alternative transcripts): 
    NM_013386.4  NM_213651.2  

    Unigene Cluster for SLC25A24:

    Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
    Hs.656870  [show with all ESTs]
    Unigene Representative Sequence: NM_013386
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000565488(uc001dvn.4) ENST00000264128 ENST00000370041(uc001dvm.3)
    ENST00000569674
    miRNA
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    hsa-let-7d hsa-miR-548k hsa-miR-218-1* hsa-miR-4263 hsa-let-7c hsa-let-7g hsa-miR-9 hsa-let-7a
    SwitchGear 3'UTR luciferase reporter plasmidSLC25A24 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AF123303.1 AJ619961.1 AJ619987.1 AK292567.1 AK304165.1 AK316304.1 AK316506.1 AL050209.1 
    BC014519.1 BC029377.1 BC068010.1 BC068561.1 

    7 DOTS entries:

    DT.121377993  DT.113065  DT.86856186  DT.426021  DT.95173708  DT.121378013  DT.95081389 

    24/132 AceView cDNA sequences (see all 132):

    AW673211 CB124548 BX101315 AW069035 BQ959355 AL050209 BC029377 AJ619961 
    BG623074 BI870734 NM_013386 AI061119 H01323 BF445689 BM772274 BQ688961 
    BC068010 BQ962873 AJ619987 AI522316 CA311758 CA393532 BQ637518 BX505986 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC25A24 expression in normal human tissues (normalized intensities)      SLC25A24 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCAGCTCTT
    SLC25A24 Expression
    About this image


    SLC25A24 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/23 selected tissues (see all 23) fully expand
     
     Colon (Gastrointestinal Tract)    fully expand to see all 5 entries
             colon ; peripheral nerve/ganglion   
             colonic mucosal (ibs)   
     
     Intestine (Gastrointestinal Tract)    fully expand to see all 4 entries
             small intestine ; glandular cells   
             small intestine   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Uterus (Reproductive System)    fully expand to see all 3 entries
             uterus, post-menopause ; glandular cells   
     
     Lung (Respiratory System)    fully expand to see all 3 entries
             lung ; pneumocytes   

    See SLC25A24 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC25A24

    SOURCE GeneReport for Unigene cluster: Hs.656870

    UniProtKB/Swiss-Prot: SCMC1_HUMAN, Q6NUK1
    Tissue specificity: Present in various cell lines (at protein level). Expressed in all tissues tested. Highly
    expressed in testis, expressed at intermediate level in small intestine and pancreas, and weakly expressed in
    kidney, spleen, liver, skeletal muscle and heart

        SABiosciences Expression via Pathway-Focused PCR Array including SLC25A24: 
              Mitochondria in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A24

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC25A24 gene from 10/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc25a241 , 5 solute carrier family 25 (mitochondrial carrier, phosphate more1, 5 87.37(n)1
    93.68(a)1
      3 (48.13 cM)5
    2297311  NM_172685.31  NP_766273.11 
     1091231495 
    chicken
    (Gallus gallus)
    Aves SLC25A241 solute carrier family 25 (mitochondrial carrier; phosphate more 75.06(n)
    76.4(a)
      424337  XM_422180.3  XP_422180.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    78(a)
    65(a)
    1 ↔ many
    1 ↔ many
    GL343211.1(2359106-2382986)
    GL345102.1(1155-9901)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3984742 hypothetical protein LOC398474 76.65(n)    BC043993.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:924701 zgc:92470 65.41(n)
    65.76(a)
      447867  NM_001004606.1  NP_001004606.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG321036
    --
    41(a)
    1 → many
    3L(12395395-12407942)
    worm
    (Caenorhabditis elegans)
    Secernentea F17E5.26
    F55A11.46
    Protein F55A11.4, isoform a
    40(a)
    40(a)
    many ↔ many
    many ↔ many
    X(12394265-12399490)
    V(11771246-11773495)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SAL1(YNL083W)4 ADP/ATP transporter; member of the Ca2+-binding subfamily more   --   14(471377-472861) 855641  NP_014316.2 
    soybean
    (Glycine max)
    eudicotyledons 445188332   -- 70.53(n)  
    rice
    (Oryza sativa)
    Liliopsida Os.268812 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 73.7(n)    AK070190.1 


    ENSEMBL Gene Tree for SLC25A24 (if available)
    TreeFam Gene Tree for SLC25A24 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC25A24 gene
    SLC25A232  SLC25A422  SLC25A252  SLC25A162  SLC25A412  SLC25A432  
    15 SIMAP similar genes for SLC25A24 using alignment to 3 protein entries:     SCMC1_HUMAN (see all proteins):
    SLC25A25    SLC25A41    SLC25A23    SLC25A16    CALML5    SLC25A4
    CALM1    CALM2    CALM3    CALML3    SLC25A32    SLC25A6
    CAPS    SLC25A31    SLC25A5

    SLC25A24 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for SLC25A24
    PGOHUM00000244135 PGOHUM00000244833


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1335 SNPs in SLC25A24 are shown (see all 1335)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs30433511,2
    C--106642303(-) GAAGC-/A/AAAA
    A
    /AAAAAA
    AAAAA
    4 -- int1 cds1 trp30--------
    rs1414923681,2
    C--106644186(+) ACTAA-/ACAC  
            
    ACACA
    2 -- int10--------
    rs345862041,2
    C--106646934(+) TAAAG-/A/A   
       A
    /AAA
    AAAAA
    4 -- int1 cds10--------
    rs1393445211,2
    C--106646935(+) TAAAG-/AAAAAAA 2 -- int10--------
    rs1997040031,2
    C--106647693(+) GGGTTG/TTTTTT 2 -- int10--------
    rs1495530001,2
    C--106666401(+) TCAAA-/AACAACAA 2 -- cds10--------
    rs678368191,2
    C--106669386(+) TATGA-/AGAG  
            
    AGAGA
    2 -- int11Minor allele frequency- AGAG:0.00CSA 2
    rs558493701,2
    C--108681168(+) GAGACAG/-TGTCA 2 -- int12Minor allele frequency- -:0.00NA CSA 4
    rs797377751,2
    C--108681168(+) GAGAC-/AG/GG 
            
    CTGTC
    2 -- int10--------
    rs567936801,2
    C--108683442(+) AAAAA-/ATCAAC 2 -- int11Minor allele frequency- A:0.00NA 2

    HapMap Linkage Disequilibrium report for SLC25A24 (108676658 - 108743471 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/35 variations for SLC25A24 (see all 35):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv59e199CNV Deletion23128226
    esv3739CNV Deletion18987735
    esv2122744CNV Deletion18987734
    esv2623047CNV Deletion19546169
    esv2675031CNV Deletion23128226
    esv2421780CNV Deletion20811451
    esv2665550CNV Deletion23128226
    esv2715906CNV Deletion23290073
    nsv820521CNV Deletion20802225
    esv22495CNV Loss19812545

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608744    OMIM disorders: --

    2 diseases for SLC25A24:    About MalaCards
    night blindness    blindness


    SLC25A24 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC25A24
    Human Genome Epidemiology (HuGE) Navigator: SLC25A24 (2 documents)

    Export disorders for SLC25A24 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC25A24 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with SLC25A24)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of the mitochondrial ATP-Mg/Pi transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution. (PubMed id 15123600)1, 2, 3 Fiermonte G....Palmieri F. (2004)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    4. Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains. (PubMed id 15054102)1, 2 del Arco A. and Satrustegui J. (2004)
    5. The mitochondrial transporter family SLC25: identifica tion, properties and physiopathology. (PubMed id 23266187)1 Palmieri F. (2013)
    6. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca(2+) buffer ing. (PubMed id 22015608)1 Traba J....Satrustegui J. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29957 HGNC: 20662 AceView: SLC25A24 Ensembl:ENSG00000085491 euGenes: HUgn29957
    ECgene: SLC25A24 H-InvDB: SLC25A24

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC25A24 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC25A24 gene:
    Search GeneIP for patents involving SLC25A24

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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