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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC25A24 Gene

protein-coding   GIFtS: 51
GCID: GC01M108677

solute carrier family 25 (mitochondrial carrier; phosphate...
 Explore 3 diseases affiliated with
SLC25A24 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC25A24    

Aliases
for SLC25A24 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member
241 2
     Calcium-Binding Mitochondrial Carrier Protein SCaMC-12
APC11 2 3     Calcium-Binding Transporter2
Mitochondrial ATP-Mg/Pi Carrier Protein 12 3     Short Calcium-Binding Mitochondrial Carrier 12
Mitochondrial Ca(2+)-Dependent Solute Carrier Protein 12 3     MCSC13
Small Calcium-Binding Mitochondrial Carrier Protein 12 3     SCAMC13
DKFZp586G01231     Solute Carrier Family 25 Member 243
SCAMC-12     

External Ids:    HGNC: 206621   Entrez Gene: 299572   Ensembl: ENSG000000854917   OMIM: 6087445   UniProtKB: Q6NUK13   

Export aliases for SLC25A24 gene to outside databases

Previous GC identifers: GC01M108033 GC01M108389 GC01M106625


Summaries
for SLC25A24 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SLC25A24:
This gene encodes a carrier protein that transports ATP-Mg exchanging it for phosphate. Multiple transcript variants
encoding different isoforms have been found for this gene. (provided by RefSeq, May 2012)

UniProtKB/Swiss-Prot: SCMC1_HUMAN, Q6NUK1
Function: Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites,
nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates
the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or
from the mitochondria




Genomic Views
for SLC25A24 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC25A24 gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   oct-B3   oct-B2   FOXL1   POU2F2   POU2F2C   POU2F1   POU2F1a   POU2F2B   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC25A24 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC25A24

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC25A24


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p13.3   Ensembl cytogenetic band:  1p13.3   HGNC cytogenetic band: 1p13.2

SLC25A24 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A24 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M108677:  view genomic region     (about GC identifiers)

Start:
 108,676,658 bp from pter      End:
 108,743,471 bp from pter
Size:
 66,814 bases      Orientation:
 minus strand

Proteins
for SLC25A24 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SCMC1_HUMAN, Q6NUK1 (See protein sequence)
Recommended Name: Calcium-binding mitochondrial carrier protein SCaMC-1  
Size: 477 amino acids; 53354 Da
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAF28888.1; Type=Frameshift; Positions=418, 464; Sequence=CAI13622.1; Type=Erroneous gene
model prediction; Sequence=CAI14512.1; Type=Erroneous gene model prediction;
Secondary accessions: B7ZAI9 Q5T331 Q5T485 Q6PJJ9 Q705K4 Q9P129
Alternative splicing: 2 isoforms:  Q6NUK1-1   Q6NUK1-2   

Explore the universe of human proteins at neXtProt for SLC25A24: NX_Q6NUK1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6NUK1

    • SLC25A24 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_037518.3  NP_998816.1  

    ENSEMBL proteins: 
     ENSP00000457733   ENSP00000264128   ENSP00000359058   ENSP00000454393  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: SLC25A24
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    Novus Biologicals SLC25A24 Proteins
    Novus Biologicals SLC25A24 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SLC25A24

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane IEA--
    GO:0016021integral to membrane IEA--


    SLC25A24 for ontologies           About GeneDecksing



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    Uscn Antibodies for SLC25A24
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    Uscn ELISAs and CLIAs for SLC25A24

    Protein Domains /
    Families
    for SLC25A24 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC25A24 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR018247 EF_Hand_1_Ca_BS
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_Ca-bd
     IPR002067 Mit_carrier
     IPR023395 Mt_carrier_dom

    Graphical View of Domain Structure for InterPro Entry Q6NUK1

    ProtoNet protein and cluster: Q6NUK1

    1 Blocks protein family: IPB002067 Mitochondrial carrier protein signature

    UniProtKB/Swiss-Prot: SCMC1_HUMAN, Q6NUK1
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 4 EF-hand domains
    Similarity: Contains 3 Solcar repeats


    Function
    for SLC25A24 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SCMC1_HUMAN, Q6NUK1
    Function: Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites,
    nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates
    the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or
    from the mitochondria
    Biophysicochemical properties: Kinetic parameters: KM=0.97 mM for AMP; KM=0.3 mM for ADP; KM=0.33 mM for ATP; KM=0.2 mM
    for ATP-Mg; KM=1.64 mM for Pi; Vmax=337 umol/min/g enzyme with AMP as substrate; Vmax=345 umol/min/g enzyme with ADP
    as substrate; Vmax=320 umol/min/g enzyme with ATP as substrate; Vmax=365 umol/min/g enzyme with ATP-Mg as substrate;
    Vmax=380 umol/min/g enzyme with Pi as substrate;

    miRNA
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    hsa-let-7b (MIRT001592)

    OriGene 3'-UTR Clone (see all 2): SLC25A24
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC25A24
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC25A24 (see all 18):
    hsa-let-7d hsa-miR-548k hsa-miR-218-1* hsa-miR-4263 hsa-let-7c hsa-let-7g hsa-miR-9 hsa-let-7a
    SwitchGear 3'UTR luciferase reporter plasmid: SLC25A24 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC25A24 (see all 7)
    OriGene shRNA RFP: SLC25A24
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC25A24

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): SLC25A24 (NM_013386)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC25A24 

    Cell Line
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    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A24

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--


    SLC25A24 for ontologies           About GeneDecksing



    Pathways & Interactions
    for SLC25A24 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC25A24

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5/6 Interacting proteins for SLC25A24 (Q6NUK12 ENSP000002641284) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ANAPC4Q9UJX52MINT-8413231 MINT-8413062
    ANAPC7Q9UJX32MINT-8413231 MINT-8413062
    BUB1BO605662MINT-8413231 MINT-8413062
    NEK2P519552MINT-8413062
    NTNG1ENSP000003590854STRING: ENSP00000359085
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0055085transmembrane transport IEA--


    SLC25A24 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC25A24 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC25A24

    1 HMDB Compound for SLC25A24    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Search CenterWatch for drugs/clinical trials and news about SLC25A24 / SCMC1 

    Transcripts
    for SLC25A24 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC25A24 gene (2 alternative transcripts): 
    NM_013386.4  NM_213651.2  

    Unigene Cluster for SLC25A24:

    Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
    Hs.656870  [show with all ESTs]
    Unigene Representative Sequence: NM_013386
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000565488(uc001dvn.4) ENST00000264128 ENST00000370041(uc001dvm.3)
    ENST00000569674

    miRNA
    Products:             		 OriGene 3'-UTR Clone (see all 2): SLC25A24
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC25A24
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC25A24 (see all 18):
    hsa-let-7d hsa-miR-548k hsa-miR-218-1* hsa-miR-4263 hsa-let-7c hsa-let-7g hsa-miR-9 hsa-let-7a
    SwitchGear 3'UTR luciferase reporter plasmid: SLC25A24 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC25A24 (see all 7)
    OriGene shRNA RFP: SLC25A24
    OriGene siRNA: SLC25A24
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC25A24
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC25A24 (see all 3)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): SLC25A24 (NM_013386)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC25A24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC25A24 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC25A24
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC25A24

    Additional cDNA sequence: 

    AF123303.1 AJ619961.1 AJ619987.1 AK292567.1 AK304165.1 AK316304.1 AK316506.1 AL050209.1 
    BC014519.1 BC029377.1 BC068010.1 BC068561.1 

    7 DOTS entries:

    DT.121377993  DT.113065  DT.86856186  DT.426021  DT.95173708  DT.121378013  DT.95081389 

    24/132 AceView cDNA sequences (see all 132):

    AA181615 BQ637518 BQ685792 BM984763 H01323 AI061119 BF447395 CA311758 
    AJ619961 NM_213651 BG623074 BX101315 AL050209 BF445689 NM_013386 BX105317 
    BQ688961 CA393532 BG779437 AW673211 BX505986 BQ962873 AW057833 CD251819 

    GeneLoc Exon Structure


    Expression
    for SLC25A24 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC25A24 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATCAGCTCTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See SLC25A24 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC25A24

    SOURCE GeneReport for Unigene cluster: Hs.656870

    UniProtKB/Swiss-Prot: SCMC1_HUMAN, Q6NUK1
    Tissue specificity: Present in various cell lines (at protein level). Expressed in all tissues tested. Highly expressed
    in testis, expressed at intermediate level in small intestine and pancreas, and weakly expressed in kidney, spleen,
    liver, skeletal muscle and heart

        SABiosciences Expression via Pathway-Focused PCR Array including SLC25A24: 
              Mitochondria in human mouse rat

    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A24

    Orthologs
    for SLC25A24 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC25A24 gene from 8/29 species (see all 29)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SLC25A241 solute carrier family 25 (mitochondrial carrier; phosphate more 75.06(n)
    76.4(a)    		   424337  XM_422180.3  XP_422180.3 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    		 --
    		 78(a)
    65(a)
    		 1 ↔ many
    1 ↔ many
    		 GL343211.1(2359272-2379699)
    GL345102.1(1155-9834)
    African clawed frog
    (Xenopus laevis)    		 Amphibia LOC3984742 hypothetical protein LOC398474 76.65(n)    BC043993.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc:924701 zgc:92470 65.41(n)
    65.76(a)    		   447867  NM_001004606.1  NP_001004606.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG321036
    		 --
    		 41(a)
    		 1 → many
    		 3L(12395395-12407942)
    worm
    (Caenorhabditis elegans)    		 Secernentea F17E5.26
    F55A11.46
    		 Probable calcium-binding mitochondrial carrier F17...
    Putative calcium-binding mitochondrial carrier F55...
    		 40(a)
    39(a)
    		 many ↔ many
    many ↔ many
    		 X(12394197-12399422)
    V(11771228-11773477)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT5G510506
    AT5G618106
    (see all 3)    		 Mitochondrial substrate carrier family protein
    (see all 3)    		 39(a)
    38(a)
    (see all 3)    		 many ↔ many
    many ↔ many
    (see all 3)    		 5(20753381-20755714)
    5(24831619-24833902)
    rice
    (Oryza sativa)    		 Liliopsida Os.268812 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 73.7(n)    AK070190.1 


    ENSEMBL Gene Tree for SLC25A24 (if available)
    TreeFam Gene Tree for SLC25A24 (if available) 

    Paralogs
    for SLC25A24 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC25A24 gene
    SLC25A232  SLC25A422  SLC25A252  SLC25A162  SLC25A412  
    15 SIMAP similar genes for SLC25A24 using alignment to 3 protein entries:     SCMC1_HUMAN (see all proteins):
    SLC25A25    SLC25A23    SLC25A41    SLC25A16    CALML5    SLC25A4
    CALM1    CALM2    CALM3    CALML3    SLC25A32    SLC25A6
    CAPS    SLC25A31    SLC25A5

    SLC25A24 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for SLC25A24
    PGOHUM00000244135 PGOHUM00000244833


    Genomic Variants
    for SLC25A24 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1067 NCBI SNPs in SLC25A24 are shown (see all 1067)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs741120291,2
    		C,--106623110(+) CAACTG/CTCGGC 2 -- ut311Minor allele frequency- C:0.50WA 2
    rs5696721,2
    		C,A,--106623276(+) TTTCCA/GTAATT 2 -- ut31 ese34Minor allele frequency- G:0.03NA WA 260
    rs5753711,2
    		C,F,A,H,--106623948(+) CATCAT/CTTGCT 2 -- ut3122Minor allele frequency- C:0.24NA NS EA WA CSA 2110
    rs561959541,2
    		C,--106624091(+) TCTGCC/AGAAGC 2 -- ut311Minor allele frequency- A:0.50WA 2
    rs412784641,2
    		C,F,--106624337(+) AGCTGA/GAAGAA 2 -- ut311Minor allele frequency- G:0.04NA 120
    rs412784661,2
    		--106624379(+) ATGCTT/CTTGCT 2 -- ut311Minor allele frequency- C:0.01NA 120
    rs124048101,2
    		C,F,H,--106624594(+) ATTTCG/AGATTC 2 -- ut315Minor allele frequency- A:0.00NS EA NA 414
    rs170210961,2
    		C,F,H,--106624738(+) TTACCA/GTCTTC 2 -- ut3110Minor allele frequency- G:0.03NA NS EA CSA WA 801
    rs760089631,2
    		--106625639(+) GCACAA/GCCAAG 2 -- int10--------
    rs5227051,2
    		C,F,A,H,--106625649(+) GACAAC/TGGGAG 2 -- int15Minor allele frequency- T:0.03NS EA WA 536

    HapMap Linkage Disequilibrium report for SLC25A24 (108676658 - 108743471 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 28 variations for SLC25A24
         15/23 CNVs (see all 23): 37397 84443 69528 74621 43731 39004 84447 97466 34673 30395 3305 31644 34672 74623 60867
         5 Indels: 74619 84446 74624 84444 74622

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    Disorders / Diseases
    for SLC25A24 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC25A24 for disorders           About GeneDecksing

    OMIM gene information: 608744    OMIM disorders: --

    3 diseases for SLC25A24:    About MalaCards
    night blindness    blindness    malaria

    Human Genome Epidemiology (HuGE) Navigator: SLC25A24 (2 documents)

    Export disorders for SLC25A24 gene to outside databases

    Publications
    for SLC25A24 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC25A24 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with SLC25A24)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of the mitochondrial ATP-Mg/Pi transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution. (PubMed id 15123600)1, 2, 3 Fiermonte G....Palmieri F. (2004)
    2. Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains. (PubMed id 15054102)1, 2 del Arco A. and Satrustegui J. (2004)
    3. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    5. SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca(2+) buffer ing. (PubMed id 22015608)1 Traba J....Satrustegui J. (2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    10. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)

    External Searches for SLC25A24 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SLC25A24 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29957 HGNC: 20662 AceView: SLC25A24 Ensembl:ENSG00000085491 euGenes: HUgn29957
    ECgene: SLC25A24 H-InvDB: SLC25A24

    Other Databases showing SLC25A24 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC25A24 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC25A24 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC25A24 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC25A24 gene:
    Search GeneIP for patents involving SLC25A24

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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