Aliases for SLC25A22 Gene
External Ids for SLC25A22 Gene
Previous GeneCards Identifiers for SLC25A22 Gene
This gene encodes a mitochondrial glutamate carrier. Mutations in this gene are associated with early infantile epileptic encephalopathy. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jul 2010]
GeneCards Summary for SLC25A22 Gene
SLC25A22 (Solute Carrier Family 25 Member 22) is a Protein Coding gene. Diseases associated with SLC25A22 include Epileptic Encephalopathy, Early Infantile, 3 and Early Myoclonic Encephalopathy. GO annotations related to this gene include symporter activity and L-glutamate transmembrane transporter activity. An important paralog of this gene is SLC25A18.
UniProtKB/Swiss-Prot for SLC25A22 Gene
Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+).