SLC25A19 Gene
protein-coding GIFtS: 53
GCID: GC17M073266
|
|
solute carrier family 25 (mitochondrial thiamine pyrophosphate...(Previous names: solute carrier family 25 (mitochondrial deoxynucleotide...)
(Previous symbol: MCPHA)
| |
Aliases
for SLC25A19 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Solute Carrier Family 25 (Mitochondrial Thiamine Pyrophosphate Carrier),Member 191 2 | | Solute Carrier Family 25 (Mitochondrial Deoxynucleotide Carrier), Member 191 2 | | DNC1 2 3 5 | | Mitochondrial Uncoupling Protein 12 3 | | MUP11 2 3 5 | | THMD32 | | MCPHA1 2 5 | | THMD42 | | TPC1 2 | | Mitochondrial Thiamine Pyrophosphate Carrier2 | | Microcephaly, Amish1 2 | | Solute Carrier Family 25 Member 193 |
Export aliases for SLC25A19 gene to outside databasesPrevious GC identifers: GC17M076328 GC17M073733 GC17M073866 GC17M070780 GC17M068679 |
Summaries
for SLC25A19 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SLC25A19:
This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein wasinitially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into thematrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrialthiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this genecause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the sameprotein, have been identified for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: TPC_HUMAN, Q9HC21Function: Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria
Gene Wiki entry for SLC25A19
|
Genomic Views
for SLC25A19 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SLC25A19 gene promoter:
ER-alpha STAT1 STAT1beta NF-kappaB STAT1alpha IRF-2 NF-kappaB2 STAT2 STAT3 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SLC25A19
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC25A19 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25.3 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.1SLC25A19 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M073266: view genomic region
(about GC identifiers)
Start:
|
73,269,061 bp from pter |
End:
|
73,285,591 bp from pter |
Size:
|
16,531 bases |
Orientation:
|
minus strand |
|
Proteins
for SLC25A19 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TPC_HUMAN, Q9HC21 (See
protein sequence)Recommended Name: Mitochondrial thiamine pyrophosphate carrier Size: 320 amino acids; 35511 Da
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Miscellaneous: The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane atan angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue(By similarity)Explore the universe of human proteins at neXtProt for SLC25A19: NX_Q9HC21
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9HC21
SLC25A19 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001119593.1 NP_001119594.1 NP_068380.3
ENSEMBL proteins: ENSP00000462401 ENSP00000397818 ENSP00000385312 ENSP00000402202 ENSP00000319574 ENSP00000463795 ENSP00000462214 ENSP00000463039 ENSP00000463720 ENSP00000462299 ENSP00000463428 ENSP00000462504 ENSP00000464457 ENSP00000364410
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SLC25A19 for ontologies About GeneDecksing
SLC25A19 Antibody Products:
Assay Products for SLC25A19: |
Protein
Domains /
Families
for SLC25A19 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SLC25A19 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9HC21ProtoNet protein and cluster: Q9HC21 UniProtKB/Swiss-Prot: TPC_HUMAN, Q9HC21Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) familySimilarity: Contains 3 Solcar repeats |
Function
for SLC25A19 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TPC_HUMAN, Q9HC21Function: Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC25A19 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC25A19 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): SLC25A19 (NM_021734) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC25A19 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC25A19 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A19 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0030233 | deoxynucleotide transmembrane transporter activity |
TAS | 11226231 |
SLC25A19 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for SLC25A19:
Animal Models:
Mouse knock-out Slc25a19tm1Mjl for SLC25A19
9 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Slc25a19):
SLC25A19 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SLC25A19 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC25A19
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
5/7 Interacting proteins for SLC25A19 (Q9HC213 ENSP000003195744) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
SLC25A19 for ontologies About GeneDecksing
|
Drugs & Compounds
for SLC25A19 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SLC25A19 for compounds About GeneDecksing
 Browse Tocris compounds for SLC25A19
5 Novoseek chemical compound relationships for SLC25A19 gene About this table
Search CenterWatch for drugs/clinical trials and news about SLC25A19 / TPC
|
Transcripts
for SLC25A19 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SLC25A19 gene (3 alternative transcripts): NM_001126121.1 NM_001126122.1 NM_021734.4 Unigene Cluster for SLC25A19: Solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 Hs.514470 [show with all ESTs]Unigene Representative Sequence: NR_03652015 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000582822 ENST00000416858(uc010dge.3 uc002jnv.4) ENST00000402418(uc002jns.4)
ENST00000442286 ENST00000320362(uc002jnu.4 uc002jnw.4 uc002jnt.4)
ENST00000580994 ENST00000583332 ENST00000580273 ENST00000579207 ENST00000580151
ENST00000581988 ENST00000582778 ENST00000584438 ENST00000579228 ENST00000375261
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC25A19 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC25A19 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): SLC25A19 (NM_021734) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC25A19 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC25A19 |
Additional cDNA sequence: AF182404.1 AJ251857.1 AK075239.1 AK097882.1 AK225881.1 AL833387.1 AY346372.1 BC001075.2 BC005120.1 BC021162.2 NR_036520.1 12 DOTS entries: DT.416044 DT.100780056 DT.75153976 DT.95224648 DT.100780058 DT.120905341 DT.92432362 DT.95240793 DT.100025021 DT.120905349 DT.100774987 DT.40200324 24/189 AceView cDNA sequences (see all 189): CR590620 AA282854 BX439332 CA430830 AI016017 T31632 CR619889 CR626101 AA814840 BM476254 CR624640 BU634181 CR623625 BI820746 BU177306 BM455504 BM797257 AI589738 AA371302 CA308303 BC001075 N26046 BI462986 BQ653688
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A19 (see all 12) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10a | · | 10b | · | 10c | · | 10d | · | 10e |
|---|
|
| SP1: | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SLC25A19
|
Expression
for SLC25A19 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SLC25A19 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See SLC25A19 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC25A19
SOURCE GeneReport for Unigene cluster: Hs.514470
UniProtKB/Swiss-Prot: TPC_HUMAN, Q9HC21Tissue specificity: Expressed in all tissues examined except for placenta. Highest levels in colon, kidney, lung,testis, spleen, and brain
SABiosciences Expression via Pathway-Focused PCR Array including SLC25A19:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC25A19
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC25A19 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC25A19 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC25A19 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A19 |
Orthologs
for SLC25A19 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SLC25A19 gene from 9/31 species (see all 31) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SLC25A191 |
solute carrier family 25 (mitochondrial thiamine pyrophosphate more |
67.82(n)
66.35(a) |
|
422123 XM_420126.3 XP_420126.2 |
lizard
(Anolis carolinensis) |
Reptilia |
SLC25A196 |
-- |
66(a) |
1 ↔ 1 |
2(114622173-114630505) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.39332 |
Transcribed sequence with weak similarity to protein more |
72.94(n) |
|
AL862936.2 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufj01c082 |
Danio rerio clone RK050A1F10 solute carrier family more |
73.62(n) |
|
AY394951.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG66083
Tpc11 |
carrier3
Thiamine pyrophosphate carrier protein 11 |
37(a)
(best of 2)3
47.16(n)1
39.13(a)1 |
|
86C73
413161 NM_141777.31 NP_650034.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
C42C1.103
hpo-121 |
mitochondrial carrier protein3
Protein HPO-121 |
42(a)3
49.22(n)1
44.63(a)1 |
|
IV(12283366-12285013)3
1834021 NM_069936.31 NP_502337.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
TPC1(YGR096W)4
TPC11 |
Mitochondrial membrane transporter that mediates uptake more4
Tpc1p1 |
42.57(n)1
30.18(a)1 |
|
7(676621-677565)4
8529881, 4 NP_011610.31 NP_011610.14 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G489701 |
Mitochondrial substrate carrier family protein |
49.53(n)
45.07(a) |
|
834956 NM_124274.3 NP_199708.1 |
rice
(Oryza sativa) |
Liliopsida |
Os01g09342001 |
hypothetical protein |
50.17(n)
43.21(a) |
|
4326831 NM_001051844.1 NP_001045309.1 |
ENSEMBL Gene Tree for SLC25A19 (if available)
TreeFam Gene Tree for SLC25A19 (if available) |
Paralogs
for SLC25A19 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SLC25A19 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SLC25A19 (73269061 - 73285591 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SLC25A19: --
Human Gene Mutation Database (HGMD): SLC25A19
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC25A19 |
|
Disorders
/ Diseases
for SLC25A19 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SLC25A19 for disorders About GeneDecksing
OMIM gene information: 606521
OMIM disorders: 607196
UniProtKB/Swiss-Prot: TPC_HUMAN, Q9HC21
Defects in SLC25A19 are the cause of microcephaly Amish type (MCPHA) [MIM:607196]; also known as Amish lethalmicrocephaly. MCPHA is an autosomal recessive metabolic disorder characterized by severe congenital microcephaly,severe 2-ketoglutaric aciduria and death within the first year Defects in SLC25A19 are the cause of thiamine metabolism dysfunction syndrome 4, bilateral striataldegeneration and progressive polyneuropathy type (THMD4) [MIM:613710]. A disease characterized by recurrent episodesof flaccid paralysis and encephalopathy associated with bilateral striatal necrosis and chronic progressivepolyneuropathy
14  diseases for SLC25A19: About MalaCardsmicrocephaly detrusor sphincter dyssynergia amish lethal microcephaly nasal cavity squamous cell carcinoma
squamous cell carcinoma insulin resistance metabolic disorders polyneuropathy
myopathy neuropathy anemia obesity
carcinoma adenocarcinoma
3 diseases from the University of Copenhagen DISEASES database for SLC25A19:Nasal cavity squamous cell carcinoma Detrusor sphincter dyssynergia Microcephaly GeneTests: SLC25A19
Amish Lethal Microcephaly
Human Genome Epidemiology (HuGE) Navigator: SLC25A19 (1 document)
Export disorders for SLC25A19 gene to outside databases
|
Publications
for SLC25A19 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SLC25A19 gene, integrated from 9 sources (see all 38):
(articles sorted by number of sources associating them with SLC25A19) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals. (PubMed id 11226231)1, 2, 3, 9 Dolce V....Walker J.E. (2001)
- SLC25A19 mutation as a cause of neuropathy and bilate ral striatal necrosis. (PubMed id 19798730)1, 2, 3 Spiegel R....Elpeleg O. (2009)
- The evidence that the DNC (SLC25A19) is not the mitochondrial deoxyribonucleotide carrier. (PubMed id 18280798)1, 2, 9 Kang J. and Samuels D.C. (2008)
- Genomic organization and mapping of the gene (SLC25A19) encoding the human mitochondrial deoxynucleotide carrier (DNC). (PubMed id 11474176)1, 3, 9 Iacobazzi V....Palmieri F. (2001)
- Mutant deoxynucleotide carrier is associated with congenital microcephaly. (PubMed id 12185364)1, 2, 9 Rosenberg M.J....Biesecker L.G. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake. (PubMed id 15539640)1, 9 Lam W....Cheng Y.C. (2005)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for SLC25A19 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SLC25A19 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SLC25A19 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SLC25A19 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SLC25A19 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/SLC25A19 |
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About This Section
| Patent Information for SLC25A19 gene:
Search GeneIP for patents involving SLC25A19
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SLC25A19 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SLC25A19 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC25A19 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC25A19 | | | OriGene Protein Over-expression Lysate for SLC25A19 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SLC25A19 | | OriGene 3'-UTR Clone for SLC25A19 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC25A19 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC25A19 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SLC25A19 | | OriGene Custom Protein Services for SLC25A19 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC25A19 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC25A19 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC25A19 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC25A19 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC25A19 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC25A19 |
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 | | | SLC25A19 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A19 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC25A19 |
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