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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC25A18 Gene

protein-coding   GIFtS: 51
GCID: GC22P018043

Solute Carrier Family 25 (Glutamate Carrier), Member 18

(Previous names: solute carrier family 25 (mitochondrial carrier), member...)
  Search for SLC25A18
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 25 (Glutamate Carrier), Member 181 2     Solute Carrier Family 25 Member 182 3
GC22 3 5     GC-22 3
Solute Carrier Family 25 (Mitochondrial Carrier), Member 181 2     Mitochondrial Glutamate Carrier 22
Glutamate/H(+) Symporter 22 3     

External Ids:    HGNC: 109881   Entrez Gene: 837332   Ensembl: ENSG000001829027   OMIM: 6093035   UniProtKB: Q9H1K43   

Export aliases for SLC25A18 gene to outside databases

Previous GC identifers: GC22P014986 GC22P016417 GC22P016423 GC22P001861


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SLC25A18 Gene: 
SLC25A18 (solute carrier family 25 (glutamate carrier), member 18) is a protein-coding gene. GO annotations related to this gene include symporter activity. An important paralog of this gene is SLC25A13.

UniProtKB/Swiss-Prot: GHC2_HUMAN, Q9H1K4
Function: Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is
cotransported with H(+)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NT_011519.10  NC_018933.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC25A18 gene promoter:
         GR   USF1   GR-beta   MIF-1   NF-kappaB   PPAR-gamma1   USF-1   PPAR-gamma2   GR-alpha   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC25A18 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC25A18

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC25A18


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q11.2   Ensembl cytogenetic band:  22q11.21   HGNC cytogenetic band: 22q11.2

SLC25A18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A18 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P018043:  view genomic region     (about GC identifiers)

Start:
18,043,139 bp from pter      End:
18,073,647 bp from pter
Size:
30,509 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GHC2_HUMAN, Q9H1K4 (See protein sequence)
Recommended Name: Mitochondrial glutamate carrier 2  
Size: 315 amino acids; 33849 Da
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein (By similarity)

Explore the universe of human proteins at neXtProt for SLC25A18: NX_Q9H1K4

Explore proteomics data for SLC25A18 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H1K4

  • SLC25A18 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC25A18 Protein Expression
    REFSEQ proteins: NP_113669.1  
    ENSEMBL proteins: 
     ENSP00000329033   ENSP00000382710  

    Human Recombinant Protein Products for SLC25A18: 
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    OriGene Protein Over-expression Lysate for SLC25A18
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    Novus Biologicals SLC25A18 Protein
    Novus Biologicals SLC25A18 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SLC25A18 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005743mitochondrial inner membrane IEA--
    GO:0016021integral to membrane IEA--

    SLC25A18 for ontologies           About GeneDecksing



    SLC25A18 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Mitochondrial glutamate carrier 2 
    Mitochondrial di- and tri-carboxylic acid transporters

    3 InterPro protein domains:
     IPR002067 Mit_carrier
     IPR023395 Mt_carrier_dom
     IPR018108 Mitochondrial_sb/sol_carrier

    Graphical View of Domain Structure for InterPro Entry Q9H1K4

    ProtoNet protein and cluster: Q9H1K4

    UniProtKB/Swiss-Prot: GHC2_HUMAN, Q9H1K4
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 3 Solcar repeats


    SLC25A18 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GHC2_HUMAN, Q9H1K4
    Function: Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is
    cotransported with H(+)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015293symporter activity IEA--
         
    SLC25A18 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC25A18:
     Upregulation of Wnt/beta-caten 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC25A18 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC25A18 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC25A18 

    miRNA
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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A18


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC25A18

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5/245 Interacting proteins for SLC25A18 (Q9H1K42, 3 ENSP000003290334) via UniProtKB, MINT, STRING, and/or I2D (see all 245)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    GRID2O434243I2D: score=1 
    AARS2Q5JTZ92MINT-8079030
    AASSQ9UDR52MINT-8079030
    ABCB7O750272MINT-8079030
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC25A18 (GHC2)

    1 HMDB Compound for SLC25A18    About this table
    CompoundSynonyms CAS #PubMed Ids
    L-Glutamic acid(2S)-2-Aminopentanedioate (see all 49)56-86-0--

    1 DrugBank Compound for SLC25A18    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    L-Glutamic Acid(2S)-2-Aminopentanedioic acid (see all 15)56-86-0target--17139284 17016423

    Search CenterWatch for drugs/clinical trials and news about SLC25A18 / GHC2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC25A18 gene: 
    NM_031481.1  

    Unigene Cluster for SLC25A18:

    Solute carrier family 25 (glutamate carrier), member 18
    Hs.282982  [show with all ESTs]
    Unigene Representative Sequence: AK095706
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000327451(uc002zmp.1) ENST00000399813(uc010gqx.3 uc002zmq.1)
    ENST00000496051 ENST00000467228 ENST00000497401 ENST00000469889
    miRNA
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    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC25A18 (see all 11):
    hsa-miR-98 hsa-let-7d hsa-miR-202 hsa-let-7c hsa-let-7i hsa-let-7e hsa-let-7g hsa-let-7b
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    Inhib. RNA
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC25A18
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC25A18

    Additional mRNA sequence: 

    AJ428203.1 AK095706.1 AK308974.1 AK309110.1 AY008285.1 BC031644.1 CR456578.1 

    8 DOTS entries:

    DT.410644  DT.100741363  DT.91979210  DT.120640396  DT.95367631  DT.100673389  DT.120640395  DT.95077978 

    24/53 AceView cDNA sequences (see all 53):

    AJ428203 H06004 AI936864 CD672841 BM920748 AI076197 BM920764 AY008285 
    BC031644 BM720069 BI756451 CR456578 CB161544 NM_031481 BI753542 Z39813 
    BP346701 BU621395 BX422384 AI206252 BP348020 AV652455 AA728784 Z43755 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A18 (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2 ^ 3a · 3b · 3c · 3d · 3e ^ 4a · 4b · 4c · 4d · 4e ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^
    SP1:                                            -     -           -     -     -           -     -     -     -     -                                             
    SP2:                                            -     -     -     -     -     -           -     -     -     -     -                                             
    SP3:                                      -     -     -           -     -     -           -     -     -     -     -                                             
    SP4:                                                              -     -     -           -     -     -     -     -                                             
    SP5:                                                                                                                                                            

    ExUns: 12a · 12b ^ 13a · 13b
    SP1:  -                     
    SP2:  -                     
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for SLC25A18

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC25A18 expression in normal human tissues (normalized intensities)      SLC25A18 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAGGCGCTG
    SLC25A18 Expression
    About this image


    SLC25A18 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Pancreas (Endocrine System)
             Pancreatic endoderm/endocrine precursor-like cells ( A scalable, suspension protocol...
     
     Gut Tube (Gastrointestinal Tract)
             Endoderm progenitor-like cells ( Generation and expansion of endodermal progenitor...
     
     Liver (Hepatobiliary System)

    See SLC25A18 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC25A18

    SOURCE GeneReport for Unigene cluster: Hs.282982
        SABiosciences Custom PCR Arrays for SLC25A18
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A18

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC25A18 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc25a181 , 5 solute carrier family 25 (mitochondrial carrier), member more1, 5 85.19(n)1
    87.94(a)1
      6 (57.00 cM)5
    718031  NM_001081048.21  NP_001074517.11 
     1207737685 
    lizard
    (Anolis carolinensis)
    Reptilia SLC25A186
    --
    Uncharacterized protein
    73(a)
    61(a)
    1 ↔ 1
    possible ortholog
    5(14001110-14008065)
    4(130662131-130678633)
    zebrafish
    (Danio rerio)
    Actinopterygii slc25a221 solute carrier family 25 (mitochondrial carrier: glutamate), more 65.37(n)
    69.48(a)
      406717  NM_213408.1  NP_998573.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG183473 carrier 51(a)
    (best of 2)
        --
    worm
    (Caenorhabditis elegans)
    Secernentea F20D1.93 Mitochondrial carrier proteins 48(a)
    (best of 2)
      X(15037393-15038468)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes AGC16
    Mitochondrial amino acid transporter, acts both as...
    12(a)
    1 → many
    XVI(600649-603357)


    ENSEMBL Gene Tree for SLC25A18 (if available)
    TreeFam Gene Tree for SLC25A18 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC25A18 gene
    SLC25A132  SLC25A122  SLC25A442  SLC25A222  
    3 SIMAP similar genes for SLC25A18 using alignment to 1 protein entry:     GHC2_HUMAN:
    SLC25A22    SLC25A12    SLC25A13

    SLC25A18 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SLC25A18
    PGOHUM00000238935


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/894 SNPs in SLC25A18 are shown (see all 894)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1827192081,2
    --1989600(+) TGGAAA/TAGAAA 1 -- us2k10--------
    rs1138959711,2
    C,F--1990222(+) TTGCCC/TAGGCT 1 -- us2k12Minor allele frequency- T:0.02NA 122
    rs59920671,2
    C,F--1990273(+) tcccgG/Agctca 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1743571,2
    C,F,A,H--1990409(+) gcctcT/Agcctc 1 -- us2k15Minor allele frequency- A:0.29NA CSA WA EA 362
    rs1481365961,2
    --1990470(+) TTTATA/GAGGAA 1 -- us2k10--------
    rs117047801,2
    C,F,H--1990532(+) AACAAA/CTATAT 1 -- us2k19Minor allele frequency- C:0.02NS EA NA 956
    rs1149620131,2
    F--1990533(+) ACAAAT/CATATG 1 -- us2k11Minor allele frequency- C:0.05WA 118
    rs563943851,2
    C,F--1990549(+) AAAGTT/AAGCAT 1 -- us2k11Minor allele frequency- A:0.04NA 120
    rs1461234011,2
    --1990617(+) TTTTGA/GAACTG 1 -- us2k10--------
    rs1169258621,2
    C,F--1990634(+) TTTAAC/TGCTTG 1 -- us2k11Minor allele frequency- T:0.01NA 120

    HapMap Linkage Disequilibrium report for SLC25A18 (18043139 - 18073647 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/30 variations for SLC25A18 (see all 30):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2533793CNV Deletion19546169
    esv2029533CNV Deletion18987734
    esv1116778CNV Deletion17803354
    esv2670900CNV Deletion23128226
    esv2657458CNV Deletion23128226
    esv2170081CNV Deletion18987734
    esv2672971CNV Deletion23128226
    esv2723950CNV Deletion23290073
    esv4931CNV Deletion18987735
    esv1371480CNV Deletion17803354

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SLC25A18 for disorders           About MalaCards
    OMIM gene information: 609303    OMIM disorders: --


    SLC25A18 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC25A18
    Human Genome Epidemiology (HuGE) Navigator: SLC25A18 (1 document)

    Export disorders for SLC25A18 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC25A18 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with SLC25A18)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of the mitochondrial glutamate transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms. (PubMed id 11897791)1, 2, 3 Fiermonte G....Walker J.E. (2002)
    2. Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere. (PubMed id 11381032)1, 2, 3 Footz T.K....McDermid H.E. (2001)
    3. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
    6. The mitochondrial transporter family SLC25: identifica tion, properties and physiopathology. (PubMed id 23266187)1 Palmieri F. (2013)
    7. A 600 kb triplication in the cat eye syndrome critical region causes anorectal, renal and preauricular anomalies in a three-generation family. (PubMed id 22395867)1 Knijnenburg J....van Zutven L.J. (2012)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome. (PubMed id 20186120)1 Richter R....Chrzanowska-Lightowlers Z.M. (2010)
    10. Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)7 Imming P....Meyer A. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83733 HGNC: 10988 AceView: SLC25A18 Ensembl:ENSG00000182902 euGenes: HUgn83733
    ECgene: SLC25A18 H-InvDB: SLC25A18

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC25A18 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC25A18 gene:
    Search GeneIP for patents involving SLC25A18

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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