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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC25A10 Gene

protein-coding   GIFtS: 61
GCID: GC17P079674

solute carrier family 25 (mitochondrial carrier; dicarboxylate...


(Previous symbol: DIC)
 Explore 11 diseases affiliated with
SLC25A10 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC25A10    

Aliases
for SLC25A10 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 25 (Mitochondrial Carrier; Dicarboxylate Transporter),
Member 101 2
DIC1 2 3 5
Dicarboxylate Ion Carrier2
Mitochondrial Dicarboxylate Carrier2
Solute Carrier Family 25 Member 103

External Ids:    HGNC: 109801   Entrez Gene: 14682   Ensembl: ENSG000001830487   OMIM: 6067945   UniProtKB: Q9UBX33   

Export aliases for SLC25A10 gene to outside databases

Previous GC identifers: GC17U990019 GC17P080239 GC17P080375 GC17P077289 GC17P079679 GC17P075125


Summaries
for SLC25A10 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SLC25A10:
This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial
membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and
other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid
synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
(provided by RefSeq, Aug 2012)

UniProtKB/Swiss-Prot: DIC_HUMAN, Q9UBX3
Function: Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or
thiosulfate across mitochondrial inner membrane

Gene Wiki entry for SLC25A10


Genomic Views
for SLC25A10 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC25A10 gene promoter:
         NRSF form 1   AP-4   Nkx2-5   LCR-F1   NRSF form 2   Roaz   HEN1   RORalpha1   HSF2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC25A10 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC25A10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC25A10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.3   Ensembl cytogenetic band:  17q25.3   HGNC cytogenetic band: 17q25.3

SLC25A10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A10 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P079674:  view genomic region     (about GC identifiers)

Start:
 79,670,404 bp from pter      End:
 79,688,042 bp from pter
Size:
 17,639 bases      Orientation:
 plus strand

Proteins
for SLC25A10 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DIC_HUMAN, Q9UBX3 (See protein sequence)
Recommended Name: Mitochondrial dicarboxylate carrier  
Size: 287 amino acids; 31282 Da
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Secondary accessions: Q542Z3 Q96BA1 Q96IP1
Alternative splicing: 2 isoforms:  Q9UBX3-1   Q9UBX3-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC25A10: NX_Q9UBX3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UBX3

    • SLC25A10 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001257817.1  NP_001257882.1  NP_036272.2  

    ENSEMBL proteins: 
     ENSP00000460597   ENSP00000328403   ENSP00000345580   ENSP00000458785   ENSP00000439565  
     ENSP00000446242  
    Reactome Protein details: Q9UBX3
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    Uscn Proteins for SLC25A10

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005739mitochondrion IDA--
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005840ribosome ----


    SLC25A10 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for SLC25A10 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC25A10 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR023395 Mt_carrier_dom
     IPR002030 Mit_uncoupling
     IPR018108 Mitochondrial_sb/sol_carrier

    Graphical View of Domain Structure for InterPro Entry Q9UBX3

    ProtoNet protein and cluster: Q9UBX3

    UniProtKB/Swiss-Prot: DIC_HUMAN, Q9UBX3
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 3 Solcar repeats


    Function
    for SLC25A10 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: DIC_HUMAN, Q9UBX3
    Function: Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or
    thiosulfate across mitochondrial inner membrane

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    Gene Ontology (GO): 5/9 molecular function terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome ----
    GO:0005310dicarboxylic acid transmembrane transporter activity TAS9733776
    GO:0005515protein binding IPI19447967
    GO:0015114phosphate ion transmembrane transporter activity ----
    GO:0015116sulfate transmembrane transporter activity ----


    SLC25A10 for ontologies           About GeneDecksing



    Pathways & Interactions
    for SLC25A10 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/10 super-pathways (see all 10) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Amino acid and oligopeptide SLC transporters
    		Amino acid and oligopeptide SLC transporters1.00
    		Transport of inorganic cations/anions and amino acids/oligopeptides0.52
    2SLC-mediated transmembrane transport
    		SLC-mediated transmembrane transport1.00
    		Transmembrane transport of small molecules0.50
    3Glucose metabolism
    		Glucose metabolism1.00
    		Gluconeogenesis0.50
    4Degradation of cysteine and homocysteine
    		Degradation of cysteine and homocysteine1.00
    		Sulfide oxidation to sulfate0.62
    5Organic anion transporters
    		Organic anion transporters1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/13        Reactome Pathways for SLC25A10 (see all 13)
        Sulfide oxidation to sulfate
    Metabolism of carbohydrates
    Metabolism
    Sulfur amino acid metabolism
    Gluconeogenesis


    1         Kegg Pathway  (Kegg details for SLC25A10):
        Proximal tubule bicarbonate reclamation


    SLC25A10 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC25A10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    5/256 Interacting proteins for SLC25A10 (Q9UBX31, 2, 3 ENSP000003455804) via UniProtKB, MINT, STRING, and/or I2D (see all 256)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KRTAP4-12Q9BQ662, 3, ENSP000003775824MINT-67782 I2D: score=5 STRING: ENSP00000377582
    ATP5A1P257052, 3MINT-8079030 I2D: score=1 
    UQCRFS1P479852, 3MINT-8079030 I2D: score=1 
    MDFIQ997501, 3, ENSP000002303214EBI-750394,EBI-724076 I2D: score=3 STRING: ENSP00000230321
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000096sulfur amino acid metabolic process TAS--
    GO:0000098sulfur amino acid catabolic process TAS--
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006006glucose metabolic process TAS--
    GO:0006094gluconeogenesis TAS--


    SLC25A10 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC25A10 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for SLC25A10

    1 HMDB Compound for SLC25A10    About this table
    CompoundSynonyms CAS #PubMed Ids
    Succinic acid1,2-Ethanedicarboxylate (see all 11)110-15-6--

    1 DrugBank Compound for SLC25A10    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Succinic acid1,2-Ethanedicarboxylic acid (see all 8)110-15-6target--16176879 16027120

    Search CenterWatch for drugs/clinical trials and news about SLC25A10 / DIC 

    Transcripts
    for SLC25A10 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
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    About This Section
    REFSEQ mRNAs for SLC25A10 gene (3 alternative transcripts): 
    NM_001270888.1  NM_001270953.1  NM_012140.4  

    Unigene Cluster for SLC25A10:

    Solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
    Hs.548187  [show with all ESTs]
    Unigene Representative Sequence: NM_001270888
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000574129 ENST00000331531(uc010dif.3) ENST00000350690(uc002kbi.3 uc010wuu.2)
    ENST00000574884 ENST00000571876 ENST00000570310 ENST00000573246 ENST00000541223
    ENST00000545862

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    Inhib. RNA
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    Additional cDNA sequence: 

    AJ131613.1 AK075249.1 AK303808.1 BC007355.2 BC015797.1 

    7 DOTS entries:

    DT.208213  DT.100760785  DT.92435440  DT.92059979  DT.95239687  DT.100747064  DT.97845473 

    24/185 AceView cDNA sequences (see all 185):

    BE272036 BM129729 AI373475 BF058424 BQ920816 AI972040 AW246762 CB111910 
    BQ943394 AW513012 BM470204 BF476113 CK431149 BI226141 NM_012140 BQ065993 
    BC007355 BU521866 BM851347 AI469842 AL582334 AI669894 BQ054381 BC015797 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A10 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b · 10c · 10d ^ 11 ^ 12a · 12b · 12c
    SP1:                    -     -                             -     -           -                             -                                             
    SP2:                    -     -                             -     -           -                             -     -                                       
    SP3:                    -     -                             -     -           -                                                                           
    SP4:                                                        -     -           -                             -     -                                       
    SP5:                    -     -                             -     -           -                       -     -     -                                       


    ECgene alternative splicing isoforms for SLC25A10

    Expression
    for SLC25A10 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC25A10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCCTCGGGCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SLC25A10 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    AdiposeBody Subcutaneous White AdiposeAdipose
    AdiposeVisceral White AdiposeAdipose
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SLC25A10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC25A10

    SOURCE GeneReport for Unigene cluster: Hs.548187

    UniProtKB/Swiss-Prot: DIC_HUMAN, Q9UBX3
    Tissue specificity: Present in high amounts in liver and kidney, and at lower levels in all the other tissues analyzed

        SABiosciences Expression via Pathway-Focused PCR Arrays including SLC25A10: 
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    In Situ
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    Orthologs
    for SLC25A10 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC25A10 gene from 9/28 species (see all 28)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SLC25A101 solute carrier family 25 (mitochondrial carrier; dicarboxylate more 81.63(n)
    86.57(a)    		   769048  XM_001232237.2  XP_001232238.2 
    lizard
    (Anolis carolinensis)    		 Reptilia SLC25A106
    		 --
    		 75(a)
    		 1 → many
    		 2(118760589-118770471)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.117392 Xenopus laevis transcribed sequence with weak similarity more 77(n)    BX846152.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc566142 similar to solute carrier family 25 (mitochondrial more 76.56(n)   394147  BC049505.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta BcDNA:GH024313
    Dic11    		 carrier3
    Dicarboxylate carrier 11    		 58(a)
    (best of 4)3
    58.33(n)1
    59.78(a)1    		   87E83
    416401  NM_142022.31  NP_650279.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea K11G12.51 , 3 mitochondrial 2-oxoglutartae3
    Protein K11G12.51    		 59(a)3
    57.95(n)1
    59.86(a)1    		   X(6759255-6760923)3
    1809401  NM_076732.41  NP_509133.11 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes DIC1(YLR348C)4
    DIC11    		 Mitochondrial dicarboxylate carrier, integral membrane more4
    Dic1p1    		 47.71(n)1
    41.26(a)1    		   12(827873-826977)4
    8510631, 4  NP_013452.11, 4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons DIC26
    UCP56
    (see all 3)    		 uncoupling protein 5
    (see all 3)    		 38(a)
    35(a)
    (see all 3)    		 many ↔ many
    many ↔ many
    (see all 3)    		 4(12686459-12687650)
    2(9563224-9564751)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 mitochondrial carrier protein, putative
    mitochondrial carrier protein, putative, expressed...
    		 35(a)
    35(a)
    		 many ↔ many
    many ↔ many
    		 9(17641594-17642559)
    8(23610377-23611993)


    ENSEMBL Gene Tree for SLC25A10 (if available)
    TreeFam Gene Tree for SLC25A10 (if available) 

    Paralogs
    for SLC25A10 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC25A10 gene
    ENSG000002626602  SLC25A112  UCP32  UCP12  UCP22  SLC25A272  SLC25A142  SLC25A302  
    10 SIMAP similar genes for SLC25A10 using alignment to 5 protein entries:     DIC_HUMAN (see all proteins):
    MRPL12    MRPL7/L12    SLC25A11    UCP2    UCP1    SLC25A14
    SLC25A30    SLC25A27    UCP3    SLC25A34

    SLC25A10 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC25A10 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/228 NCBI SNPs in SLC25A10 are shown (see all 228)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 17 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1895232811,2
    		--79677327(+) TGTGGG/TTTGGG 3 -- us2k10--------
    rs1495607401,2
    		--79677359(+) TTCAGC/TCCTGT 3 -- us2k10--------
    rs1148458061,2
    		F,--79677370(+) CTTGCA/GGGTGG 3 -- us2k11Minor allele frequency- G:0.03WA 118
    rs794693561,2
    		F,--79677536(+) CATCTC/TGGTTT 3 -- us2k11Minor allele frequency- T:0.04WA 118
    rs353876851,2
    		C,F,--79677583(+) TCTGCG/AGGACT 3 -- us2k16Minor allele frequency- A:0.11NA CSA WA EA 364
    rs754942581,2
    		F,--79677638(+) CTCTTG/TCTGGG 3 -- us2k11Minor allele frequency- T:0.07WA 118
    rs1832730481,2
    		--79677670(+) CACTTC/TCCCTG 3 -- us2k10--------
    rs65656241,2
    		C,F,A,H,--79677750(+) TGCATT/CTGCGC 3 -- us2k122Minor allele frequency- C:0.31NS EA NA WA CSA 2353
    rs791939691,2
    		--79677792(+) AGGCTC/TGGTGC 3 -- us2k10--------
    rs72174521,2
    		C,--79677797(+) TGGTGC/TGGGCA 3 -- us2k14Minor allele frequency- T:0.21NA WA 124

    HapMap Linkage Disequilibrium report for SLC25A10 (79670404 - 79688042 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for SLC25A10
         3 CNVs: 30036 73071 30034

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for SLC25A10

    Disorders / Diseases
    for SLC25A10 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC25A10 for disorders           About GeneDecksing

    OMIM gene information: 606794    OMIM disorders: --

    11 diseases for SLC25A10:    About MalaCards
    clivus chordoma    breast malignant phyllodes tumor    turner syndrome    patau syndrome
    edwards syndrome    gonadoblastoma    retinitis pigmentosa    herpes simplex
    amenorrhea    down syndrome    retinitis

    4 diseases from the University of Copenhagen DISEASES database for SLC25A10:
    Turner syndrome     Clivus chordoma     Leukemia     Gonadoblastoma
    Human Genome Epidemiology (HuGE) Navigator: SLC25A10 (1 document)

    Export disorders for SLC25A10 gene to outside databases

    Publications
    for SLC25A10 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC25A10 gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with SLC25A10)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier family. (PubMed id 10585886)1, 2, 9 Fiermonte G....Palmieri F. (1999)
    2. Identification of dicarboxylate carrier Slc25a10 as malate transporter in de novo fatty acid synthesis. (PubMed id 16027120)1, 7 Mizuarai S....Kotani H. (2005)
    3. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Assignment of the human dicarboxylate carrier gene (DIC) to chromosome 17 band 17q25.3. (PubMed id 10072589)1, 3 Pannone E....Palmieri F. (1998)
    6. The sequence, bacterial expression, and functional reconstitution of the rat mitochondrial dicarboxylate transporter cloned via distant homologs in yeast and Caenorhabditis elegans. (PubMed id 9733776)1, 3 Fiermonte G....Walker J.E. (1998)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    9. Biochemical and phosphoproteomic analysis of the helix -loop-helix protein E47. (PubMed id 22354994)1 Teachenor R....Murre C. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    External Searches for SLC25A10 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
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    NCBI Bookshelf
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    Genome Databases showing SLC25A10 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1468 HGNC: 10980 AceView: SLC25A10 Ensembl:ENSG00000183048 euGenes: HUgn1468
    ECgene: SLC25A10 Kegg: 1468 H-InvDB: SLC25A10

    Other Databases showing SLC25A10 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC25A10 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC25A10 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC25A10 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC25A10 gene:
    Search GeneIP for patents involving SLC25A10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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