Aliases for SLC24A4 Gene
External Ids for SLC24A4 Gene
Previous GeneCards Identifiers for SLC24A4 Gene
This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
GeneCards Summary for SLC24A4 Gene
SLC24A4 (Solute Carrier Family 24 (Sodium/Potassium/Calcium Exchanger), Member 4) is a Protein Coding gene. Diseases associated with SLC24A4 include amelogenesis imperfecta, type iia5 and amelogenesis imperfecta hypomaturation type. Among its related pathways are Visual Cycle in Retinal Rods and The phototransduction cascade. GO annotations related to this gene include symporter activity and antiporter activity. An important paralog of this gene is SLC24A2.
UniProtKB/Swiss-Prot for SLC24A4 Gene
Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived. May play a role in calcium transport during amelogenesis (By similarity).