SLC24A4 Gene
protein-coding GIFtS: 53
GCID: GC14P092788
|
|
solute carrier family 24 (sodium/potassium/calcium exchanger),...
| |
Aliases
for SLC24A4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Solute Carrier Family 24 (Sodium/Potassium/Calcium Exchanger), Member 41 2 | | SLC24A22 5 | | NCKX41 2 3 5 | | Sodium/Potassium/Calcium Exchanger 42 | | Na(+)/K(+)/Ca(2+)-Exchange Protein 42 3 | | Solute Carrier Family 24 Member 43 | | SHEP62 5 | | |
Export aliases for SLC24A4 gene to outside databasesPrevious GC identifers: GC14P090403 GC14P086604 GC14P090778 GC14P091858 GC14P072971 |
Summaries
for SLC24A4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SLC24A4:
This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. Alternative splicingresults in multiple transcript variants.(provided by RefSeq, Jul 2010)
UniProtKB/Swiss-Prot: NCKX4_HUMAN, Q8NFF2Function: Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+)
|
Genomic Views
for SLC24A4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SLC24A4 gene promoter:
HSF2 HOXA5 ARP-1 SEF-1 (1)
Other transcription factors
Search SABiosciences Chromatin IP Primers for SLC24A4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC24A4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q32.12 Ensembl cytogenetic band: 14q32.12 HGNC cytogenetic band: 14q32.12SLC24A4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P092788: view genomic region
(about GC identifiers)
Start:
|
92,788,925 bp from pter |
End:
|
92,967,825 bp from pter |
Size:
|
178,901 bases |
Orientation:
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plus strand |
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Proteins
for SLC24A4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NCKX4_HUMAN, Q8NFF2 (See
protein sequence)Recommended Name: Sodium/potassium/calcium exchanger 4 precursor Size: 622 amino acids; 69042 Da
Subcellular location: Membrane; Multi-pass membrane protein
Caution: It is uncertain whether Met-1 or Met-18 is the initiator
Sequence caution: Sequence=AAH69653.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAM76070.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAM76071.1;Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAC04715.1; Type=Miscellaneousdiscrepancy; Note=Probable cloning artifact; Sequence=CAD38903.1; Type=Erroneous initiation; Note=TranslationN-terminally extended;
Secondary accessions: B4DHE7 B9ZVY2 Q8N8U6 Q8NCX1 Q8NFF0 Q8NFF1Alternative splicing: 4 isoforms: Q8NFF2-1 Q8NFF2-2 Q8NFF2-3 Q8NFF2-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SLC24A4: NX_Q8NFF2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NFF2
SLC24A4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_705932.2 NP_705933.2 NP_705934.1
ENSEMBL proteins: ENSP00000376948 ENSP00000433302 ENSP00000431840 ENSP00000452099 ENSP00000432464 ENSP00000298877 ENSP00000337789 Reactome Protein details: Q8NFF2
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
TAS | -- | | GO:0016021 | integral to membrane |
IEA | -- |
SLC24A4 for ontologies About GeneDecksing
SLC24A4 Antibody Products:
Assay Products for SLC24A4: |
Protein
Domains /
Families
for SLC24A4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SLC24A4 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NFF2ProtoNet protein and cluster: Q8NFF2 1 Blocks protein family: IPB004837 Sodium/calcium exchanger membrane region
UniProtKB/Swiss-Prot: NCKX4_HUMAN, Q8NFF2Similarity: Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily |
Function
for SLC24A4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NCKX4_HUMAN, Q8NFF2Function: Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC24A4 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC24A4 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): SLC24A4 (NM_153648) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC24A4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC24A4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC24A4 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0015293 | symporter activity |
IEA | -- | | GO:0015297 | antiporter activity |
IEA | -- |
SLC24A4 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SLC24A4:
Animal Models:
Mouse knock-out Slc24a4tm1.1Hazh for SLC24A4
3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Slc24a4):
SLC24A4 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SLC24A4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Sodium-coupled transporters and pumps | | | 2 | SLC-mediated transmembrane transport | | | 3 | Visual Cycle in Retinal Rods | | | 4 | Amino acid and oligopeptide SLC transporters | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for SLC24A4
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for SLC24A4
4 
Reactome Pathways for SLC24A4
SLC24A4 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC24A4
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
SLC24A4 for ontologies About GeneDecksing
|
Drugs & Compounds
for SLC24A4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SLC24A4
2 HMDB Compounds for SLC24A4 About this table
Search CenterWatch for drugs/clinical trials and news about SLC24A4 / NCKX4
|
Transcripts
for SLC24A4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SLC24A4 gene (3 alternative transcripts): NM_153646.3 NM_153647.3 NM_153648.3 Unigene Cluster for SLC24A4: Solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 Hs.385530 [show with all ESTs]Unigene Representative Sequence: NM_15364710 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000393265(uc001yai.3 uc010twn.2) ENST00000531433(uc010twm.2)
ENST00000532405(uc001yak.3) ENST00000554461 ENST00000525557(uc010auj.3)
ENST00000554925 ENST00000556739 ENST00000526482(uc001yan.3) ENST00000298877
ENST00000351924
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC24A4 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC24A4 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): SLC24A4 (NM_153648) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC24A4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC24A4 |
Additional cDNA sequence: AF520704.1 AF520705.1 AF520706.1 AK093061.1 AK096171.1 AK295059.1 AK295234.1 BC034805.1 BC050357.1 BC069653.1 BX648995.1 8 DOTS entries: DT.100019942 DT.91996294 DT.435079 DT.100019941 DT.99935501 DT.101979936 DT.99932774 DT.100019944 24/28 AceView cDNA sequences (see all 28): AL042630 AF520705 M79260 BM720360 BC069653 AL834225 NM_153646 NM_153648 NM_153647 BX103620 AF520704 AF520706 M79261 BC037863 BX493831 BX648995 BX509825 AW337854 CD000254 AK096171 BI753920 BI461118 W90717 BF990322
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for SLC24A4 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b |
|---|
|
| SP1: | | | - | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | |
ECgene alternative splicing isoforms for SLC24A4
|
Expression
for SLC24A4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SLC24A4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See SLC24A4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC24A4
SOURCE GeneReport for Unigene cluster: Hs.385530
UniProtKB/Swiss-Prot: NCKX4_HUMAN, Q8NFF2Tissue specificity: Expressed abundantly in all regions of the brain, aorta, lung and thymus. Expressed at lower levelsin the stomach and intestine
SABiosciences Custom PCR Arrays for SLC24A4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC24A4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC24A4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC24A4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC24A4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC24A4 |
Orthologs
for SLC24A4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SLC24A4 gene from 4/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SLC24A41 |
solute carrier family 24 (sodium/potassium/calcium more |
76.31(n)
82.09(a) |
|
772279 XM_001235437.2 XP_001235438.1 |
lizard
(Anolis carolinensis) |
Reptilia |
SLC24A46 |
-- |
71(a) |
1 ↔ 1 |
1(11398121-11433810) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.127072 |
Transcribed sequence with moderate similarity to protein more |
78.54(n) |
|
BI878483.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG28933
CG10901 |
calcium, potassium:sodium antiporter3
CG10901 |
48(a)
(best of 3)3
55.35(n)1
47.71(a)1 |
|
405511 NM_141202.31 NP_649459.31 |
ENSEMBL Gene Tree for SLC24A4 (if available)
TreeFam Gene Tree for SLC24A4 (if available) |
Paralogs
for SLC24A4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SLC24A4 gene
- SLC8A32 SLC24A32 SLC24A52 SLC8A12 SLC24A62 SLC8A22 SLC24A12 SLC24A22
4 SIMAP similar genes for SLC24A4 using alignment to 3 protein entries: NCKX4_HUMAN (see all proteins):SLC24A3 SLC24A1 SLC24A2 SLC24A5
SLC24A4 for paralogs About GeneDecksing
|
Genomic Variants
for SLC24A4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: NCKX4_HUMAN, Q8NFF2Polymorphism: Genetic variants in SLC24A4 define the skin/hair/eye pigmentation variation locus 6 (SHEP6) [MIM:210750].Hair, eye and skin pigmentation are among the most visible examples of human phenotypic variation, with a broad normalrange that is subject to substantial geographic stratification. In the case of skin, individuals tend to have lighterpigmentation with increasing distance from the equator. By contrast, the majority of variation in human eye and haircolor is found among individuals of European ancestry, with most other human populations fixed for brown eyes andblack hair
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SLC24A4 (92788925 - 92967825 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for SLC24A4
5 Indels: 45311 40063 11765 11766 25459 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC24A4 |
|
Disorders
/ Diseases
for SLC24A4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SLC24A4 for disorders About GeneDecksing
OMIM gene information: 609840
OMIM disorders: 210750
9  diseases for SLC24A4: About MalaCardsskin/hair/eye pigmentation 6, blond/brown hair skin/hair/eye pigmentation 6, blue/green eyes oculocutaneous albinism cutaneous malignant melanoma
rosacea albinism melanoma hypertension
retinitis
1 disease from the University of Copenhagen DISEASES database for SLC24A4:Oculocutaneous albinism Human Genome Epidemiology (HuGE) Navigator: SLC24A4 (9 documents)
Export disorders for SLC24A4 gene to outside databases
|
Publications
for SLC24A4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SLC24A4 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with SLC24A4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning of a fourth member of the potassium-dependent sodium-calcium exchanger gene family, NCKX4. (PubMed id 12379639)1, 2, 9 Li X.-F.... Lytton J. (2002)
- Genetic determinants of hair, eye and skin pigmentation in Europeans. (PubMed id 17952075)1, 2 Sulem P.... Stefansson K. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes. (PubMed id 21546767)1 Murea M....Freedman B.I. (2011)
- Reverse mode Na+/Ca2+ exchange mediated by STIM1 cont ributes to Ca2+ influx in airway smooth muscle following agonist stimulation. (PubMed id 21126331)1 Liu B....Hall I.P. (2010)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Web-based, participant-driven studies yield novel gen etic associations for common traits. (PubMed id 20585627)1 Eriksson N....Mountain J. (2010)
- Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma. (PubMed id 19710684)1 Duffy D.L....Montgomery G.W. (2010)
- A genome-wide association study of hypertension and b lood pressure in African Americans. (PubMed id 19609347)1 Adeyemo A....Rotimi C. (2009)
|
External Searches for SLC24A4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SLC24A4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SLC24A4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SLC24A4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SLC24A4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SLC24A4 gene:
Search GeneIP for patents involving SLC24A4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SLC24A4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SLC24A4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC24A4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC24A4 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SLC24A4 | | OriGene 3'-UTR Clone for SLC24A4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC24A4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC24A4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SLC24A4 | | OriGene Custom Protein Services for SLC24A4 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC24A4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC24A4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC24A4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC24A4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC24A4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC24A4 |
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| | | | Search Tocris compounds for SLC24A4 |
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 | | | SLC24A4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC24A4 |
|  |  |  | | | | Search ThermoFisher Antibodies for SLC24A4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC24A4 |
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