Aliases for SLC24A3 Gene
External Ids for SLC24A3 Gene
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008]
GeneCards Summary for SLC24A3 Gene
SLC24A3 (Solute Carrier Family 24 (Sodium/Potassium/Calcium Exchanger), Member 3) is a Protein Coding gene. Among its related pathways are Visual Cycle in Retinal Rods and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include symporter activity and calcium, potassium:sodium antiporter activity. An important paralog of this gene is SLC24A4.
UniProtKB/Swiss-Prot for SLC24A3 Gene
Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).