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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC24A3 Gene

protein-coding   GIFtS: 53
GCID: GC20P019141

Solute Carrier Family 24 (Sodium/Potassium/Calcium Exchanger),...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 24 (Sodium/Potassium/Calcium Exchanger), Member
31 2
NCKX32 3 5
Solute Carrier Family 24 Member 32 3
Na(+)/K(+)/Ca(2+)-Exchange Protein 32 3
Sodium Calcium Exchanger2
Sodium/Potassium/Calcium Exchanger 32

External Ids:    HGNC: 109771   Entrez Gene: 574192   Ensembl: ENSG000001850527   OMIM: 6098395   UniProtKB: Q9HC583   

Export aliases for SLC24A3 gene to outside databases

Previous GC identifers: GC20P019181 GC20P019188


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC24A3 Gene:
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and
electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1
intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 (PubMed
11294880)).(supplied by OMIM, Mar 2008)

GeneCards Summary for SLC24A3 Gene: 
SLC24A3 (solute carrier family 24 (sodium/potassium/calcium exchanger), member 3) is a protein-coding gene. Diseases associated with SLC24A3 include tako-tsubo cardiomyopathy, and brain ischemia, and among its related super-pathways are Transmembrane transport of small molecules and Amino acid and oligopeptide SLC transporters. GO annotations related to this gene include calcium, potassium:sodium antiporter activity and symporter activity. An important paralog of this gene is SLC24A5.

UniProtKB/Swiss-Prot: NCKX3_HUMAN, Q9HC58
Function: Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.2  NT_011387.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC24A3 gene promoter:
         SRF   p53   Nkx2-2   SRF (504 AA)   AP-4   LCR-F1   AREB6   FOXJ2 (long isoform)   Cart-1   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC24A3 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC24A3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC24A3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p13   Ensembl cytogenetic band:  20p11.23   HGNC cytogenetic band: 20p13

SLC24A3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC24A3 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P019141:  view genomic region     (about GC identifiers)

Start:
19,193,290 bp from pter      End:
19,703,581 bp from pter
Size:
510,292 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NCKX3_HUMAN, Q9HC58 (See protein sequence)
Recommended Name: Sodium/potassium/calcium exchanger 3 precursor  
Size: 644 amino acids; 71992 Da
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: B1AKV7 Q9BQJ9 Q9BQL7 Q9BQY3 Q9H519

Explore the universe of human proteins at neXtProt for SLC24A3: NX_Q9HC58

Explore proteomics data for SLC24A3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9HC58

  • SLC24A3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC24A3 Protein Expression
    REFSEQ proteins: NP_065740.2  
    ENSEMBL proteins: 
     ENSP00000333519  
    Reactome Protein details: Q9HC58
    Human Recombinant Protein Products for SLC24A3: 
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for SLC24A3 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IEA--

    SLC24A3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Sodium/potassium/calcium exchanger 3 
    SLC24 family of sodium/potassium/calcium exchangers

    2 InterPro protein domains:
     IPR004481 K/Na/Ca-exchanger
     IPR004837 NaCa_Exmemb

    Graphical View of Domain Structure for InterPro Entry Q9HC58

    ProtoNet protein and cluster: Q9HC58

    1 Blocks protein domain: IPB004837 Sodium/calcium exchanger membrane region

    UniProtKB/Swiss-Prot: NCKX3_HUMAN, Q9HC58
    Similarity: Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily


    SLC24A3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NCKX3_HUMAN, Q9HC58
    Function: Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008273calcium, potassium:sodium antiporter activity IEA--
    GO:0015293symporter activity IEA--
         
    SLC24A3 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for SLC24A3:
     Increased circadian period len  Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC24A3 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC24A3 
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    miRNA
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    8/39 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC24A3 (see all 39):
    hsa-miR-548j hsa-miR-15a hsa-miR-503 hsa-miR-25 hsa-miR-301a hsa-miR-424 hsa-miR-548a-5p hsa-miR-548d-5p
    SwitchGear 3'UTR luciferase reporter plasmidSLC24A3 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC24A3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1SLC-mediated transmembrane transport
    SLC-mediated transmembrane transport0.50
    Transmembrane transport of small molecules0.50
    2Amino acid and oligopeptide SLC transporters
    Transport of inorganic cations/anions and amino acids/oligopeptides0.52
    3Sodium-coupled transporters and pumps
    Sodium/Calcium exchangers0.30
    4Visual Cycle in Retinal Rods
    Visual Cycle in Retinal Rods

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for SLC24A3
        Visual Cycle in Retinal Rods

    4        Reactome Pathways for SLC24A3
        Sodium/Calcium exchangers
    SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of inorganic cations/anions and amino acids/oligopeptides



    SLC24A3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC24A3

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport TAS--
    GO:0055085transmembrane transport TAS--

    SLC24A3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC24A3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC24A3 (NCKX3)

    2 HMDB Compounds for SLC24A3    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    SodiumSodium (see all 2)7440-23-5--

    10/17 Novoseek inferred chemical compound relationships for SLC24A3 gene (see all 17)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    p-mca 80.9 4 17446465 (1), 17668452 (1), 16796818 (1), 17051729 (1)
    3',4'-dichlorobenzamil 78.1 2 15010500 (1)
    sea 0400 72.2 1 11877314 (1)
    calcium 65.1 71 10652193 (3), 9520864 (2), 17419759 (2), 8382966 (2) (see all 42)
    n-methyl-d-glucamine 60.1 1 15060069 (1)
    sodium 59.5 18 8410703 (2), 9212080 (1), 17805013 (1), 18523740 (1) (see all 11)
    ryanodine 47.3 5 16317512 (1), 19525500 (1), 9520864 (1), 19460074 (1) (see all 5)
    ouabain 44.7 3 15554913 (2), 8382966 (1)
    mgatp 33.6 1 11897850 (1)
    amiloride 32.8 3 11600230 (2), 15010500 (1)

    Search CenterWatch for drugs/clinical trials and news about SLC24A3 / NCKX3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC24A3 gene: 
    NM_020689.3  

    Unigene Cluster for SLC24A3:

    Solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
    Hs.654790  [show with all ESTs]
    Unigene Representative Sequence: NM_020689
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000328041(uc002wrl.3)

    miRNA
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    hsa-miR-548j hsa-miR-15a hsa-miR-503 hsa-miR-25 hsa-miR-301a hsa-miR-424 hsa-miR-548a-5p hsa-miR-548d-5p
    SwitchGear 3'UTR luciferase reporter plasmidSLC24A3 3' UTR sequence
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    Additional mRNA sequence: 

    AF169257.2 AF288087.1 

    2 DOTS entries:

    DT.312468  DT.97764313 

    24/68 AceView cDNA sequences (see all 68):

    BU580564 BM090857 AI753456 AW302348 AI655223 BG055727 CD514688 BE671771 
    BM090639 CA389783 T03762 BM711865 BU581020 AI224564 AL603345 BE714260 
    BE714200 F12855 AA827422 AA127240 BU727587 AI091786 AA195627 F10455 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC24A3 expression in normal human tissues (normalized intensities)      SLC24A3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTGTTCACT
    SLC24A3 Expression
    About this image


    SLC24A3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/7 selected tissues (see all 7) fully expand
     
     Fibroblast (Uncategorized)    fully expand to see all 2 entries
             Human Gingival Fibroblasts (HGF)   
     
     Tendon & Ligament
             Human periodontal ligament Fibroblasts (HPLF)   
     
     Neural Tube (Nervous System)
             Mesencephalic Floor Plate
     
     Uncategorized (Uncategorized)
             PureStem Progenitor ES-198
     
     Heart (Cardiovascular System)
             Atrioventricular Canal Cells Atrioventricular Canal

    See SLC24A3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC24A3

    SOURCE GeneReport for Unigene cluster: Hs.654790

    UniProtKB/Swiss-Prot: NCKX3_HUMAN, Q9HC58
    Tissue specificity: Abundant in the brain. Expressed at low levels in the aorta, uterus and intestine

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC24A3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SLC24A3 gene from 5/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc24a31 , 5 solute carrier family 24 (sodium/potassium/calcium more1, 5 89.7(n)1
    97.47(a)1
      2 (71.08 cM)5
    942491  NM_053195.21  NP_444425.11 
     1451677545 
    chicken
    (Gallus gallus)
    Aves SLC24A31 solute carrier family 24 (sodium/potassium/calcium more 81.05(n)
    92.24(a)
      421244  XM_419316.3  XP_419316.3 
    lizard
    (Anolis carolinensis)
    Reptilia SLC24A36
    solute carrier family 24 (sodium/potassium/calcium...
    79(a)
    1 ↔ 1
    4(80134886-80392654)
    zebrafish
    (Danio rerio)
    Actinopterygii slc24a31 solute carrier family 24 (sodium/potassium/calcium more 71.38(n)
    75.92(a)
      557196  XM_680210.4  XP_685302.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG28931 , 3 calcium, potassium:sodium antiporter3
    CG28931
    46(a)
    (best of 3)3
    52.21(n)1
    43.36(a)1
      33549921  NM_001015260.21  NP_001015260.31 


    ENSEMBL Gene Tree for SLC24A3 (if available)
    TreeFam Gene Tree for SLC24A3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC24A3 gene
    SLC24A52  SLC8B12  SLC24A42  SLC24A12  SLC24A22  
    4 SIMAP similar genes for SLC24A3 using alignment to 1 protein entry:     NCKX3_HUMAN:
    SLC24A4    SLC24A2    SLC24A1    SLC24A5

    SLC24A3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/10407 SNPs in SLC24A3 are shown (see all 10407)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0280244
    ----see VAR_0280242 L P mis40--------
    VAR_0280254
    ----see VAR_0280252 V I mis40--------
    rs58408351,2
    C--19173721(+) GGGGG-/AG    
       
    /G/GG
    TGCCC
    1 -- int11CSA 2
    rs61060301,2
    C,F,A--19191319(+) GAGCTA/TGTGTT 1 -- us2k111Minor allele frequency- T:0.40NA WA CSA EA 372
    rs1914331991,2
    --19191379(+) CCCTCG/TTTTTC 1 -- us2k10--------
    rs60459081,2
    C,F,A--19191404(+) TTTGAA/GTGACT 1 -- us2k112Minor allele frequency- G:0.33NA WA CSA EA 374
    rs1152351941,2
    C,F--19191564(+) AAAGCA/GAAGGG 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1817582671,2
    --19191582(+) CTCAGC/GCATTG 1 -- us2k10--------
    rs41419811,2
    C,F--19191679(+) CTCCCG/TGGGTG 1 -- us2k15Minor allele frequency- T:0.39NA CSA EA 127
    rs114783641,2
    C--19191790(+) AGGTC-/GGGGGG 1 -- us2k12Minor allele frequency- G:0.00NA CSA 4

    HapMap Linkage Disequilibrium report for SLC24A3 (19193290 - 19443290 bp, first 250kb of SLC24A3)

    Structural Variations
         Database of Genomic Variants (DGV) 10/12 variations for SLC24A3 (see all 12):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2722274CNV Deletion23290073
    esv2670085CNV Deletion23128226
    nsv3316CNV Insertion18451855
    esv2652551CNV Insertion19546169
    esv267761CNV Insertion20981092
    esv273939CNV Insertion20981092
    nsv3317CNV Insertion18451855
    nsv3315CNV Loss18451855
    nsv527125CNV Loss19592680
    nsv833938CNV Loss17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609839    OMIM disorders: --

    10 diseases for SLC24A3:    About MalaCards
    tako-tsubo cardiomyopathy    brain ischemia    ischemia    congestive heart failure
    malignant glioma    multiple sclerosis    cerebritis    retinitis
    endotheliitis    neuronitis


    SLC24A3 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    4 Novoseek inferred disease relationships for SLC24A3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    arrhythmia 38.6 5 15653340 (1), 9653715 (1), 12555155 (1), 16079546 (1)
    heart failure 38.1 5 15653340 (1), 7864717 (1), 19661061 (1), 16079546 (1)
    myocardial ischemia 13.6 1 15653340 (1)
    ischemia 5.54 3 11257426 (2), 18373324 (1)

    Genetic Association Database (GAD): SLC24A3
    Human Genome Epidemiology (HuGE) Navigator: SLC24A3 (2 documents)

    Export disorders for SLC24A3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC24A3 gene, integrated from 9 sources (see all 108):
    (articles sorted by number of sources associating them with SLC24A3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3. (PubMed id 11294880)1, 2, 9 Kraev A.... Lytton J. (2001)
    2. Genome-wide association study of lung function decline in adults with and without asthma. (PubMed id 22424883)1, 4 Imboden M....Probst-Hensch N.M. (2012)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associate d with serum MMP-1 levels. (PubMed id 20031604)1, 4 Cheng Y.C....Pollin T.I. (2009)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    6. Distinct expression of the calcium exchangers, NCKX3 and NCX1, and their regulation by steroid in the human endometrium during the m enstrual cycle. (PubMed id 21321244)1 Yang H....Jeung E.B. (2011)
    7. Genome-wide association for smoking cessation success: participants in the Patch in Practice trial of nicotine replacement. (PubMed id 20235792)4 Uhl G.R....Munafo M.R. (2010)
    8. Chromosome 6p22 locus associated with clinically aggressive neuroblastoma. (PubMed id 18463370)4 Maris J.M....Hakonarson H. (2008)
    9. Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study. (PubMed id 17903306)4 Newton-Cheh C....Larson M.G. (2007)
    10. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57419 HGNC: 10977 AceView: SLC24A3 Ensembl:ENSG00000185052 euGenes: HUgn57419
    ECgene: SLC24A3 H-InvDB: SLC24A3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC24A3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC24A3 gene:
    Search GeneIP for patents involving SLC24A3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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