SLC22A7 Gene
protein-coding GIFtS: 52
GCID: GC06P043263
|
|
solute carrier family 22 (organic anion transporter), member...
| |
Aliases
for SLC22A7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Solute Carrier Family 22 (Organic Anion Transporter), Member 71 2 | | Organic Anion Transporter 22 3 | | OAT21 2 3 5 | | HOAT21 | | NLT1 2 3 | | Liver-Specific Transporter2 | | Novel Liver Transporter2 3 | | Solute Carrier Family 22 Member 72 |
Export aliases for SLC22A7 gene to outside databasesPrevious GC identifers: GC06P043268 GC06P043312 GC06P043373 GC06P042985 |
Summaries
for SLC22A7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SLC22A7:
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, someof which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to thebasolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have beendescribed. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: S22A7_HUMAN, Q9Y694Function: Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2,prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol,5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate
Gene Wiki entry for SLC22A7
|
Genomic Views
for SLC22A7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SLC22A7 gene promoter:
COUP-TF1 COUP-TF COUP HNF-4alpha2 HNF-4alpha1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SLC22A7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC22A7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.1 Ensembl cytogenetic band: 6p21.1 HGNC cytogenetic band: 6p21.1SLC22A7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P043263: view genomic region
(about GC identifiers)
Start:
|
43,263,432 bp from pter |
End:
|
43,273,276 bp from pter |
Size:
|
9,845 bases |
Orientation:
|
plus strand |
|
Proteins
for SLC22A7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: S22A7_HUMAN, Q9Y694 (See
protein sequence)Recommended Name: Solute carrier family 22 member 7 Size: 548 amino acids; 60026 Da
Subcellular location: Basolateral cell membrane; Multi-pass membrane protein. Note=Apical side of the renal tubule
Secondary accessions: B2CZX6 Q5T046 Q5T048 Q5T050 Q9H2W5Alternative splicing: 4 isoforms: Q9Y694-1 Q9Y694-2 Q9Y694-3 Q9Y694-4 Explore the universe of human proteins at neXtProt for SLC22A7: NX_Q9Y694
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y694
SLC22A7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_006663.2 NP_696961.2
ENSEMBL proteins: ENSP00000416052 ENSP00000411818 ENSP00000434707 ENSP00000361670 ENSP00000361666 ENSP00000361655 ENSP00000393836 Reactome Protein details: Q9Y694
Human Recombinant Protein Products for SLC22A7:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
SLC22A7 for ontologies About GeneDecksing
SLC22A7 Antibody Products:
Assay Products for SLC22A7: |
Protein
Domains /
Families
for SLC22A7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SLC22A7 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y694ProtoNet protein and cluster: Q9Y694 UniProtKB/Swiss-Prot: S22A7_HUMAN, Q9Y694Similarity: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family |
Function
for SLC22A7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: S22A7_HUMAN, Q9Y694Function: Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2,prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol,5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarateBiophysicochemical properties: Kinetic parameters: KM=713 nM for prostaglandin E2; KM=440 uM for tetracycline; Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008514 | organic anion transmembrane transporter activity |
-- | -- | | GO:0015347 | sodium-independent organic anion transmembrane transporter activity |
TAS | 9650585 |
SLC22A7 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC22A7 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC22A7 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SLC22A7 (NM_006672) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC22A7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC22A7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC22A7 |
|
Pathways & Interactions
for SLC22A7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | SLC-mediated transmembrane transport | | | 2 | Fluoropyrimidine Activity | | | 3 | Organic cation/anion/zwitterion transport | | | 4 | Zidovudine Pathway, Pharmacokinetics/Pharmacodynamics | | | 5 | Bile secretion | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for SLC22A7
5 
Reactome Pathways for SLC22A7
2  PharmGKB Pathways for SLC22A7
1 
Kegg Pathway (Kegg details for SLC22A7):
SLC22A7 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC22A7
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
SLC22A7 for ontologies About GeneDecksing
|
Drugs & Compounds
for SLC22A7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SLC22A7 for compounds About GeneDecksing
 Browse Tocris compounds for SLC22A7
5 HMDB Compounds for SLC22A7 About this table
10/34 DrugBank Compounds for SLC22A7 (see all 34) About this table
4 Novoseek chemical compound relationships for SLC22A7 gene About this table
Search CenterWatch for drugs/clinical trials and news about SLC22A7 / S22A7
|
Transcripts
for SLC22A7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SLC22A7 gene (2 alternative transcripts): NM_006672.3 NM_153320.2 Unigene Cluster for SLC22A7: Solute carrier family 22 (organic anion transporter), member 7 Hs.485438 [show with all ESTs]Unigene Representative Sequence: NM_1533209 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000480882 ENST00000487175 ENST00000451757 ENST00000449231 ENST00000498232
ENST00000372589(uc010jyl.1 uc003out.3) ENST00000372585(uc021yzt.1)
ENST00000372574(uc003ous.3) ENST00000436107
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC22A7 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC22A7 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): SLC22A7 (NM_006672) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC22A7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC22A7 |
Additional cDNA sequence: AF210455.1 AK290796.1 AK290806.1 AK309570.1 AK314822.1 AY050498.1 BC017963.1 BC033805.1 12 DOTS entries: DT.100019750 DT.100759232 DT.443865 DT.95268336 DT.100759230 DT.121405390 DT.421185 DT.97792715 DT.97834798 DT.121405579 DT.121405719 DT.40273127 24/64 AceView cDNA sequences (see all 64): AW237757 CB161620 BX112596 AA702356 BF196005 NM_006672 NM_153320 R29132 BC017963 AI016020 BM923779 BF197339 N74370 R00498 BX118061 R00599 BC033805 BX496425 BX494457 BG432766 BG430546 BM923554 AA705161 AF210455
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SLC22A7 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | - | | | | - | | | | | | | | - | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | - | | | | - | | | | | | | | | | - | | | | |
| SP3: | | | | | | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | - | | - | | | | - | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SLC22A7
|
Expression
for SLC22A7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SLC22A7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAGCCAACA
About this image
See SLC22A7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC22A7
SOURCE GeneReport for Unigene cluster: Hs.485438
UniProtKB/Swiss-Prot: S22A7_HUMAN, Q9Y694Tissue specificity: Expressed in liver and kidney
SABiosciences Expression via Pathway-Focused PCR Array including SLC22A7:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC22A7
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC22A7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC22A7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC22A7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC22A7 |
Orthologs
for SLC22A7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SLC22A7 gene from 5/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SLC22A71 |
solute carrier family 22 (organic anion transporter), more |
59.88(n)
54.21(a) |
|
416712 NM_001199438.1 NP_001186367.1 |
lizard
(Anolis carolinensis) |
Reptilia |
SLC22A76-- |
-- |
50(a)46(a) |
1 ↔ 1possible ortholog |
2(143562289-143588351) 2(143593295-143613964) |
zebrafish
(Danio rerio) |
Actinopterygii |
slc22a7b6slc22a7a6(see all 6) |
solute carrier family 22 (organic anion transporte...solute carrier family 22 (organic anion transporte...(see all 6) |
45(a)44(a)(see all 6) |
possible ortholog1 ↔ 1(see all 6) |
17(21832872-21840683) 11(31605199-31618420) |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG86543 |
organic cation porter |
32(a)
(best of 11) |
|
56F6 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
ZK455.8a3 |
membrane transporter |
29(a)
(best of 5) |
|
X(11381686-11385364) -- |
ENSEMBL Gene Tree for SLC22A7 (if available)
TreeFam Gene Tree for SLC22A7 (if available) |
Paralogs
for SLC22A7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SLC22A7 gene
- SLC22A112 SLC22A52 SLC22A82 SLC22A12 SLC22A242 SLC22A42 SLC22A92 SLC22A22
- SLC22A102 SLC22A132 SLC22A62 SLC22A152 SLC22A122 SLC22A32 SLC22A252 SLC22A162
18/21 SIMAP similar genes for SLC22A7 using alignment to 4 protein entries: S22A7_HUMAN (see all proteins)
(see all similar genes):SLC22A8 SLC22A16 SVOPL UST6 SLC22A20 SLC22A6
SLC22A10 SLC22A13 SLC22A24 SLC22A25 SLC22A11 SLC22A5
OAT7 SLC22A4 SLC22A9 SLC22A12 SLC22A14 SLC22A15
SLC22A7 for paralogs About GeneDecksing
|
Genomic Variants
for SLC22A7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SLC22A7 (43263432 - 43273276 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SLC22A7: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC22A7 |
|
Disorders
/ Diseases
for SLC22A7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SLC22A7 for disorders About GeneDecksing
OMIM gene information: 604995
OMIM disorders: --
8  diseases for SLC22A7: About MalaCardsnominal aphasia citrin deficiency aphasia citrullinemia
vaginitis obesity thyroiditis hepatitis
2 Novoseek disease relationships for SLC22A7 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| hyperbilirubinemia |
62.2 |
3 |
15965581 (1), 20514852 (1), 15319464 (1) |
| g6pd deficiency |
61.8 |
1 |
15319464 (1) |
Human Genome Epidemiology (HuGE) Navigator: SLC22A7 (1 document)
Export disorders for SLC22A7 gene to outside databases
|
Publications
for SLC22A7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SLC22A7 gene, integrated from 9 sources (see all 66):
(articles sorted by number of sources associating them with SLC22A7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins. (PubMed id 11907186)1, 2, 7 Kimura H.... Endou H. (2002)
- Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors. (PubMed id 12023506)1, 2, 7 Enomoto A.... Endou H. (2002)
- Human organic anion transporters mediate the transport of tetracycline. (PubMed id 11855680)1, 2, 7 Babu E.... Endou H. (2002)
- Isolation of a family of organic anion transporters from human liver and kidney. (PubMed id 11327718)1, 2, 7 Sun W.... Erion M.D. (2001)
- Identification of multispecific organic anion transporter 2 expressed predominantly in the liver. (PubMed id 9650585)1, 3, 7 Sekine T....Endou H. (1998)
- Assignment of liver-specific organic anion transporte r (SLC22A7) to human chromosome 6 bands p21.2-->p21.1 using radiation hybrid s. (PubMed id 10773670)1, 3, 9 Kok L.D....Waye M.M. (2000)
- Identification of genetic polymorphisms of human OAT1 and OAT2 genes and their relationship to hOAT2 expression in human liver. (PubMed id 19854166)1, 9 Shin H.J....Shin J.G. (2010)
- Possible involvement of organic anion transporter 2 on the interaction of theophylline with erythromycin in the human liver. (PubMed id 15708966)7, 9 Kobayashi Y....Yamamoto T. (2005)
- Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]). (PubMed id 15901346)2, 9 Kobayashi Y....Yamamoto T. (2005)
- Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics. (PubMed id 12650826)7, 9 Khamdang S....Endou H. (2003)
|
External Searches for SLC22A7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SLC22A7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SLC22A7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SLC22A7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SLC22A7 | Pharmacogenomics, SNPs, Pathways | | NIEHS-SNPs | http://egp.gs.washington.edu/data/slc22a7/ |
|
| | |
About This Section
| Patent Information for SLC22A7 gene:
Search GeneIP for patents involving SLC22A7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SLC22A7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SLC22A7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC22A7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC22A7 | | | OriGene Protein Over-expression Lysate for SLC22A7 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SLC22A7 | | OriGene 3'-UTR Clone for SLC22A7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC22A7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC22A7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SLC22A7 | | OriGene Custom Protein Services for SLC22A7 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC22A7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC22A7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC22A7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC22A7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC22A7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC22A7 |
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| | | | Search Tocris compounds for SLC22A7 |
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 | | | SLC22A7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC22A7 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for SLC22A7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC22A7 |
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