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Aliases for SLC22A6 Gene

Aliases for SLC22A6 Gene

  • Solute Carrier Family 22 (Organic Anion Transporter), Member 6 2 3
  • OAT1 3 4 6
  • PAHT 3 4 6
  • Renal Organic Anion Transporter 1 3 4
  • Organic Anion Transporter 1 3 4
  • PAH Transporter 3 4
  • HROAT1 3 4
  • HOAT1 3 4
  • HPAHT 3 4
  • Solute Carrier Family 22 Member 6 3
  • Para-Aminohippurate Transporter 3
  • ROAT1 3

External Ids for SLC22A6 Gene

Previous GeneCards Identifiers for SLC22A6 Gene

  • GC11M065256
  • GC11M064319
  • GC11M062519
  • GC11M062500
  • GC11M062744
  • GC11M059073

Summaries for SLC22A6 Gene

Entrez Gene Summary for SLC22A6 Gene

  • The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for SLC22A6 Gene

SLC22A6 (Solute Carrier Family 22 (Organic Anion Transporter), Member 6) is a Protein Coding gene. Diseases associated with SLC22A6 include bipolar i disorder. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include inorganic anion exchanger activity and sodium-independent organic anion transmembrane transporter activity. An important paralog of this gene is SLC22A12.

UniProtKB/Swiss-Prot for SLC22A6 Gene

  • Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3-azido-3-deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP) and edaravone sulfate. PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), sulindac, diclofenac, carprofen, glutarate and okadaic acid (By similarity). PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, furosemide, indomethacin, bumetamide, losartan, probenecid, phenol red, urate, and alpha-ketoglutarate.

Gene Wiki entry for SLC22A6 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC22A6 Gene

Genomics for SLC22A6 Gene

Regulatory Elements for SLC22A6 Gene

Genomic Location for SLC22A6 Gene

Start:
62,936,385 bp from pter
End:
62,985,023 bp from pter
Size:
48,639 bases
Orientation:
Minus strand

Genomic View for SLC22A6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC22A6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC22A6 Gene

Proteins for SLC22A6 Gene

  • Protein details for SLC22A6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4U2R8-S22A6_HUMAN
    Recommended name:
    Solute carrier family 22 member 6
    Protein Accession:
    Q4U2R8
    Secondary Accessions:
    • A8MY93
    • B2D0R6
    • O95187
    • O95742
    • Q7LDA0
    • Q8N192
    • Q9NQA6
    • Q9NQC2
    • Q9UBG6
    • Q9UEQ8

    Protein attributes for SLC22A6 Gene

    Size:
    563 amino acids
    Molecular mass:
    61816 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLC22A6 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC22A6 Gene

Proteomics data for SLC22A6 Gene at MOPED

Post-translational modifications for SLC22A6 Gene

  • Glycosylated. Glycosylation at Asn-113 may occur at a secondary level. Glycosylation is necessary for proper targeting of the transporter to the plasma membrane.
  • Glycosylation at Asn39, Asn56, Asn92, Asn97, and Asn113
  • Modification sites at PhosphoSitePlus

Other Protein References for SLC22A6 Gene

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for SLC22A6

No data available for DME Specific Peptides for SLC22A6 Gene

Domains for SLC22A6 Gene

Gene Families for SLC22A6 Gene

Protein Domains for SLC22A6 Gene

Suggested Antigen Peptide Sequences for SLC22A6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q4U2R8

UniProtKB/Swiss-Prot:

S22A6_HUMAN :
  • Q4U2R8
Domain:
  • Multiple cysteine residues are necessary for proper targeting to the plasma membrane.
Family:
  • Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
genes like me logo Genes that share domains with SLC22A6: view

Function for SLC22A6 Gene

Molecular function for SLC22A6 Gene

GENATLAS Biochemistry:
solute carrier protein family 22,member A6,polyspecific transporter for organic cations,mediating the coupled exchange of alpha-ketoglutarate with multiple organic ions,including p-aminohippurate (PAH),expressed strongly in kidney,weakly in brain
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=9.3 uM for PAH (isoform 1) {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; KM=4 uM for PAH (isoform 2) {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; KM=11 uM for edaravone {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; KM=46 uM for cidofovir {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; KM=30 uM for adefovir {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; KM=5.77 uM for 2,4-D {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; KM=23.5 uM for HA {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; KM=14 uM for IA {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; KM=20.5 uM for IS {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; KM=141 uM for CMPF {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; Vmax=534 pmol/min/mg enzyme for 2,4-D uptake {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; Vmax=430 pmol/min/mg enzyme for HA uptake {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; Vmax=110 pmol/min/mg enzyme for IA uptake {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; Vmax=216 pmol/min/mg enzyme for IS uptake {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473}; Vmax=801 pmol/min/mg enzyme for CMPF uptake {ECO:0000269 PubMed:10462545, ECO:0000269 PubMed:10964714, ECO:0000269 PubMed:12538807, ECO:0000269 PubMed:15846473};
UniProtKB/Swiss-Prot Function:
Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3-azido-3-deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP) and edaravone sulfate. PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), sulindac, diclofenac, carprofen, glutarate and okadaic acid (By similarity). PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, furosemide, indomethacin, bumetamide, losartan, probenecid, phenol red, urate, and alpha-ketoglutarate.

Gene Ontology (GO) - Molecular Function for SLC22A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005452 inorganic anion exchanger activity IDA 15037815
GO:0005515 protein binding IPI 16189514
GO:0008514 organic anion transmembrane transporter activity IMP 22169006
GO:0015075 ion transmembrane transporter activity --
GO:0015301 anion:anion antiporter activity --
genes like me logo Genes that share ontologies with SLC22A6: view
genes like me logo Genes that share phenotypes with SLC22A6: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC22A6

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SLC22A6 Gene

Localization for SLC22A6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC22A6 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC22A6 Gene COMPARTMENTS Subcellular localization image for SLC22A6 gene
Compartment Confidence
plasma membrane 5
endoplasmic reticulum 1
extracellular 1
lysosome 1

Gene Ontology (GO) - Cellular Components for SLC22A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IDA 14749323
GO:0005901 caveola IEA --
GO:0016021 integral component of membrane --
GO:0016323 basolateral plasma membrane IDA 15037815
genes like me logo Genes that share ontologies with SLC22A6: view

Pathways for SLC22A6 Gene

genes like me logo Genes that share pathways with SLC22A6: view

PCR Array Products

Gene Ontology (GO) - Biological Process for SLC22A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006820 anion transport --
GO:0015711 organic anion transport IMP 22169006
GO:0015742 alpha-ketoglutarate transport IDA 9950961
GO:0031427 response to methotrexate IEA --
GO:0034220 ion transmembrane transport --
genes like me logo Genes that share ontologies with SLC22A6: view

Compounds for SLC22A6 Gene

(2) HMDB Compounds for SLC22A6 Gene

Compound Synonyms Cas Number PubMed IDs
Calcium
  • Ca
7440-70-2
Sodium
  • Sodium
7440-23-5

(111) Drugbank Compounds for SLC22A6 Gene

Compound Synonyms Cas Number Type Actions PubMed IDs
Acetaminophen
  • Acetaminofen
103-90-2 transporter inhibitor
Acetazolamide
  • Acetamidothiadiazolesulfonamide
59-66-5 transporter inhibitor
Acetylcysteine
616-91-1 transporter
Acetylsalicylic acid
  • 2-Acetoxybenzenecarboxylic acid
50-78-2 transporter inhibitor
Acyclovir
  • 9-Hyroxyethoxymethylguanine
59277-89-3 transporter substrate inhibitor

(49) Novoseek inferred chemical compound relationships for SLC22A6 Gene

Compound -log(P) Hits PubMed IDs
glutaric acid 90 2
probenecid 86.1 11
estrone sulfate 85.1 5
indoxyl sulfate 77.2 4
steviol 73.5 7

(1) PharmGKB related drug/compound annotations for SLC22A6 Gene

Drug/compound Annotation
dabrafenib
genes like me logo Genes that share compounds with SLC22A6: view

Transcripts for SLC22A6 Gene

Unigene Clusters for SLC22A6 Gene

Solute carrier family 22 (organic anion transporter), member 6:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC22A6

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC22A6 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b
SP1: -
SP2:
SP3: - -
SP4: -

Relevant External Links for SLC22A6 Gene

GeneLoc Exon Structure for
SLC22A6
ECgene alternative splicing isoforms for
SLC22A6

Expression for SLC22A6 Gene

mRNA expression in normal human tissues for SLC22A6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC22A6 Gene

This gene is overexpressed in Kidney - Cortex (47.1).

Protein differential expression in normal tissues for SLC22A6 Gene

This gene is overexpressed in Urine (41.5), Plasma (18.5), and Kidney (9.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SLC22A6 Gene

SOURCE GeneReport for Unigene cluster for SLC22A6 Gene Hs.369252

mRNA Expression by UniProt/SwissProt for SLC22A6 Gene

Q4U2R8-S22A6_HUMAN
Tissue specificity: Strongly expressed in kidney and to a lower extent in liver, skeletal muscle, brain and placenta. Found at the basolateral membrane of the proximal tubule.
genes like me logo Genes that share expressions with SLC22A6: view

Expression partners for SLC22A6 Gene

In Situ Assay Products

Orthologs for SLC22A6 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC22A6 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SLC22A6 35
  • 88.38 (n)
  • 86.13 (a)
SLC22A6 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLC22A6 35
  • 89.8 (n)
  • 91.62 (a)
SLC22A6 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc22a6 35
  • 85.36 (n)
  • 86.21 (a)
Slc22a6 16
Slc22a6 36
  • 86 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SLC22A6 35
  • 99.45 (n)
  • 99.64 (a)
SLC22A6 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Slc22a6 35
  • 86.18 (n)
  • 88 (a)
oppossum
(Monodelphis domestica)
Mammalia SLC22A6 36
  • 58 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 41 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 54 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100490266 35
  • 56.76 (n)
  • 52.66 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.23285 35
zebrafish
(Danio rerio)
Actinopterygii oatx 35
  • 53.81 (n)
  • 48.2 (a)
slc22a6l 36
  • 50 (a)
OneToMany
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9767 35
fruit fly
(Drosophila melanogaster)
Insecta CG13610 37
  • 29 (a)
CG14855 37
  • 23 (a)
CG14857 37
  • 24 (a)
CG16727 37
  • 23 (a)
CG17751 37
  • 23 (a)
CG17752 37
  • 22 (a)
CG3790 37
  • 30 (a)
CG5592 37
  • 26 (a)
CG6126 37
  • 28 (a)
CG6231 37
  • 24 (a)
CG6356 37
  • 29 (a)
CG6600 37
  • 28 (a)
CG8654 37
  • 30 (a)
worm
(Caenorhabditis elegans)
Secernentea F52F12.1a 37
  • 28 (a)
K05F1.6 37
  • 26 (a)
oct-1 37
  • 28 (a)
ZK455.8a 37
  • 28 (a)
ZK455.8b 37
  • 28 (a)
Species with no ortholog for SLC22A6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC22A6 Gene

ENSEMBL:
Gene Tree for SLC22A6 (if available)
TreeFam:
Gene Tree for SLC22A6 (if available)

Paralogs for SLC22A6 Gene

Pseudogenes.org Pseudogenes for SLC22A6 Gene

genes like me logo Genes that share paralogs with SLC22A6: view

Variants for SLC22A6 Gene

Sequence variations from dbSNP and Humsavar for SLC22A6 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs521800 -- 62,978,478(-) cccag(C/G)tactc intron-variant
rs1062973 -- 62,981,329(-) CTCAC(A/C)CTGAG synonymous-codon, reference
rs2097073 -- 62,982,632(-) CAACC(A/C)CAGAA intron-variant
rs2097074 -- 62,982,430(-) CACTC(A/C)TACTT intron-variant
rs2276300 -- 62,981,227(+) CCTGG(A/G)AGGTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC22A6 Gene

Variant ID Type Subtype PubMed ID
esv34011 CNV Loss 18971310

Relevant External Links for SLC22A6 Gene

HapMap Linkage Disequilibrium report
SLC22A6
Human Gene Mutation Database (HGMD)
SLC22A6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC22A6 Gene

Disorders for SLC22A6 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for SLC22A6 Gene in MalaCards »

(1) Diseases for SLC22A6 Gene including...

(1) University of Copenhagen DISEASES for SLC22A6 Gene

(3) Novoseek inferred disease relationships for SLC22A6 Gene

Disease -log(P) Hits PubMed IDs
renal failure acute 13.6 1
immunodeficiency 7.4 2
renal disease 1.61 1

Relevant External Links for SLC22A6

Genetic Association Database (GAD)
SLC22A6
Human Genome Epidemiology (HuGE) Navigator
SLC22A6
genes like me logo Genes that share disorders with SLC22A6: view

No data available for OMIM , UniProtKB/Swiss-Prot and Genatlas for SLC22A6 Gene

Publications for SLC22A6 Gene

  1. Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C. (PMID: 9950961) Lu R. … Schuster V.L. (Am. J. Physiol. 1999) 2 3 4 23 25
  2. Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6). (PMID: 15914676) Bleasby K. … Pritchard J.B. (J. Pharmacol. Exp. Ther. 2005) 3 4 23 48
  3. Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3). (PMID: 10049739) Race J.E. … Holtzman E.J. (Biochem. Biophys. Res. Commun. 1999) 3 4 23 25
  4. The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1. (PMID: 10462545) Cihlar T. … Sweet D.H. (Mol. Pharmacol. 1999) 3 4 23 25
  5. Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney. (PMID: 9887087) Hosoyamada M. … Endou H. (Am. J. Physiol. 1999) 3 4 23 25

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