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Aliases for SLC22A24 Gene

Aliases for SLC22A24 Gene

  • Solute Carrier Family 22 Member 24 2 3 5
  • Solute Carrier Family 22, Member 24 2 3
  • NET46 3

External Ids for SLC22A24 Gene

Previous GeneCards Identifiers for SLC22A24 Gene

  • GC11M062644
  • GC11M062603
  • GC11M062847
  • GC11M059176

Summaries for SLC22A24 Gene

Entrez Gene Summary for SLC22A24 Gene

  • SLC22A24 belongs to a large family of transmembrane proteins that function as uniporters, symporters, and antiporters to transport organic ions across cell membranes (Jacobsson et al., 2007 [PubMed 17714910]).[supplied by OMIM, Mar 2008]

GeneCards Summary for SLC22A24 Gene

SLC22A24 (Solute Carrier Family 22 Member 24) is a Protein Coding gene. GO annotations related to this gene include transmembrane transporter activity. An important paralog of this gene is SLC22A12.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC22A24 Gene

Genomics for SLC22A24 Gene

Regulatory Elements for SLC22A24 Gene

Enhancers for SLC22A24 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SLC22A24 on UCSC Golden Path with GeneCards custom track

Genomic Location for SLC22A24 Gene

63,079,255 bp from pter
63,144,221 bp from pter
64,967 bases
Minus strand

Genomic View for SLC22A24 Gene

Genes around SLC22A24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC22A24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC22A24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC22A24 Gene

Proteins for SLC22A24 Gene

  • Protein details for SLC22A24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Solute carrier family 22 member 24
    Protein Accession:

    Protein attributes for SLC22A24 Gene

    322 amino acids
    Molecular mass:
    35933 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC22A24 Gene

Proteomics data for SLC22A24 Gene at MOPED

Post-translational modifications for SLC22A24 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC22A24 Gene

No data available for DME Specific Peptides for SLC22A24 Gene

Domains & Families for SLC22A24 Gene

Gene Families for SLC22A24 Gene

Protein Domains for SLC22A24 Gene


Suggested Antigen Peptide Sequences for SLC22A24 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
  • Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
genes like me logo Genes that share domains with SLC22A24: view

Function for SLC22A24 Gene

genes like me logo Genes that share phenotypes with SLC22A24: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SLC22A24 Gene

Localization for SLC22A24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC22A24 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SLC22A24 Gene COMPARTMENTS Subcellular localization image for SLC22A24 gene
Compartment Confidence
plasma membrane 5

No data available for Gene Ontology (GO) - Cellular Components for SLC22A24 Gene

Pathways & Interactions for SLC22A24 Gene

SuperPathways for SLC22A24 Gene

No Data Available

Interacting Proteins for SLC22A24 Gene

Gene Ontology (GO) - Biological Process for SLC22A24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043252 sodium-independent organic anion transport IBA --
genes like me logo Genes that share ontologies with SLC22A24: view

No data available for Pathways by source and SIGNOR curated interactions for SLC22A24 Gene

Drugs & Compounds for SLC22A24 Gene

No Compound Related Data Available

Transcripts for SLC22A24 Gene

mRNA/cDNA for SLC22A24 Gene

(6) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC22A24 Gene

Solute carrier family 22, member 24:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC22A24 Gene

No ASD Table

Relevant External Links for SLC22A24 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC22A24 Gene

mRNA expression in normal human tissues for SLC22A24 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC22A24 Gene

This gene is overexpressed in Kidney - Cortex (x34.1) and Liver (x14.1).

SOURCE GeneReport for Unigene cluster for SLC22A24 Gene Hs.375139

genes like me logo Genes that share expression patterns with SLC22A24: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SLC22A24 Gene

Orthologs for SLC22A24 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SLC22A24 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SLC22A9 35
  • 73.67 (n)
  • 60.69 (a)
-- 36
  • 64 (a)
(Canis familiaris)
Mammalia SLC22A9 35
  • 74.52 (n)
  • 64.13 (a)
(Mus musculus)
Mammalia Slc22a19 35
  • 67.15 (n)
  • 53.01 (a)
Slc22a19 16
Slc22a27 36
  • 53 (a)
(Rattus norvegicus)
Mammalia Slc22a24 35
  • 67.51 (n)
  • 54.99 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 42 (a)
-- 36
  • 39 (a)
(Pan troglodytes)
Mammalia SLC22A24 36
  • 98 (a)
Species with no ortholog for SLC22A24:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SLC22A24 Gene

Gene Tree for SLC22A24 (if available)
Gene Tree for SLC22A24 (if available)

Paralogs for SLC22A24 Gene

(15) SIMAP similar genes for SLC22A24 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with SLC22A24: view

Variants for SLC22A24 Gene

Sequence variations from dbSNP and Humsavar for SLC22A24 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs948060 -- 63,118,847(-) AAATT(C/G)TGACA intron-variant, reference, missense
rs1211549 -- 63,113,951(-) aaagg(A/G)agccc intron-variant
rs1939736 -- 63,099,023(+) ATGAA(G/T)AAATT intron-variant
rs1939741 -- 63,101,015(-) TGCTT(C/G)TGCTT intron-variant
rs1939742 -- 63,100,775(-) CCTTT(G/T)TCAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC22A24 Gene

Variant ID Type Subtype PubMed ID
esv34011 CNV Loss 18971310
nsv517447 CNV Loss 19592680
nsv897625 CNV Loss 21882294
nsv897626 CNV Loss 21882294
nsv468587 CNV Loss 19166990
nsv522971 CNV Loss 19592680
esv1629652 CNV Insertion 17803354
esv2744607 CNV Deletion 23290073
esv1159693 CNV Deletion 17803354

Variation tolerance for SLC22A24 Gene

Gene Damage Index Score: 11.00; 92.06% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for SLC22A24 Gene

Disorders for SLC22A24 Gene

Relevant External Links for SLC22A24

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SLC22A24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC22A24 Gene

Publications for SLC22A24 Gene

  1. Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family. (PMID: 17714910) Jacobsson J.A. … Fredriksson R. (Genomics 2007) 2 3 4 67
  2. Genome-wide association study of maternal and inherited loci for conotruncal heart defects. (PMID: 24800985) Agopian A.J. … Goldmuntz E. (PLoS ONE 2014) 3
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SLC22A24 Gene

Sources for SLC22A24 Gene