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SLC22A18 Gene

protein-coding   GIFtS: 50

GC11P002877
solute carrier family 22, member 18
(Previous names: solute carrier family 22 (organic cation transporter), member 1-like )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: ORCTL2, BWSCR1A, IMPT1, SLC22A1L)
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Aliases &
Descriptions
for SLC22A18

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
BWR1A 1, 2, 3
BWSCR1A 2, 3
DKFZp667A184 2
HET 2, 3
IMPT1 2, 3
ITM 1, 2, 3
ORCTL-2 3
ORCTL2 2, 3
OTTHUMP00000011732 2
OTTHUMP00000011733 2
SLC22A1L 2, 3
TSSC5 1, 2, 3
p45-BWR1A 2, 3
Descriptions
Beckwith-Wiedemann syndrome chromosomal region 1 candidate
gene A protein 3
Beckwith-Wiedemann syndrome chromosome region 1, candidate
A 2
Efflux transporter-like protein 2, 3
Imprinted multi-membrane spanning polyspecific
transporter-related protein 1 3
Organic cation transporter-like protein 2 3
Solute carrier family 22 member 1-like 3
Tumor-suppressing STF cDNA 5 protein 3
Tumor-suppressing subchromosomal transferable fragment
candidate gene 5 protein 3
imprinted multi-membrane spanning polyspecific
transporter-related protein 2
organic cation transporter-like 2 2
p45 Beckwith-Wiedemann region 1A 2
p45-Beckwith-Wiedemann region 1 A 3
solute carrier family 22 (organic cation transporter),
member 1-like 1, 2
solute carrier family 22, member 18 2
tumor suppressing subtransferable candidate 5 2
tumor-suppressing STF cDNA 5 2
External Ids
HGNC: 109641
Entrez Gene: 50022
UniProtKB: Q96BI13
Ensembl: ENSG000001106287
Search outside databases for aliases for SLC22A18 gene

Previous GC identifer: GC11P002885

Summaries
for SLC22A18

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for SLC22A18:
This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted
gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have
been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma,
adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in
malignancies and disease that involve this region as well as the transport of chloroquine- and
quinidine-related compounds in the kidney. Two alternative transcripts encoding the same isoform
have been described. [provided by RefSeq]

UniProtKB/Swiss-Prot: S22AI_HUMAN, Q96BI1
Function: May act as a transporter of organic cations based on a proton efflux antiport mechanism.
May play a role in the transport of chloroquine and quinidine-related compounds in kidney

Genomic Location
for SLC22A18

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the SLC22A18 gene  

Entrez Gene cytogenetic band: 11p15.5   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.5

SLC22A18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P002877:     (about GC identifiers)

Start:
 2,877,527 bp from pter
End:
 2,903,052 bp from pter
Size:
 25,526 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000011.8  NT_009237.17  

Proteins
for SLC22A18

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: S22AI_HUMAN, Q96BI1 (See protein sequence)
Recommended Name: Solute carrier family 22 member 18  
Size: 424 amino acids; 44846 Da
Subunit: Interacts with RNF167
Subcellular location: Apical cell membrane; Multi-pass membrane protein (Potential). Note=Localized
at the apical membrane surface of renal proximal tubules
Caution: It is uncertain whether Met-1 or Met-17 is the initiator
Secondary accessions: O14906 O43562 O60485 O60680 Q7LDS5 Q7LGF7

REFSEQ proteins (2 alternative transcripts): 
NP_002546.3  NP_899056.2  


ENSEMBL proteins: 
ENSP00000369948 ENSP00000307859 ENSP00000311139 


Human Recombinant Proteins 
Browse Drug Discovery Central at Invitrogen for human recombinant proteins
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich  
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Recombinant Proteins from Abcam (Solute carrier family 22 member 18)
Human Recombinant Proteins from Abnova (SLC22A18)
                Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005886 plasma membrane TAS9744804
GO:0016021 integral to membrane TAS9499412
GO:0016324 apical plasma membrane IEA--
About this table

Antibodies for SLC22A18: 
Browse Antibodies Central at Invitrogen
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse Antibodies at Sigma-Aldrich
Browse R&D Systems for Antibodies
Antibodies from Abcam (Solute carrier family 22 member 18), each with their AbpromiseSM
Monoclonal and Polyclonal Antibodies from Abnova (SLC22A18)
Novus Biologicals Antibody for SLC22A18

Assays for SLC22A18: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Browse biochemical assays available from Enzo Life Sciences

Protein Domains/
Families
for SLC22A18

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q96BI1

UniProtKB/Swiss-Prot: S22AI_HUMAN, Q96BI1
Similarity: Belongs to the major facilitator superfamily. Organic cation transporter family

Gene Function
for SLC22A18

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (SLC22A18)
Browse for Gene Knock-down Tools from Millipore
Abnova Chimera RNAi Products for Gene knock-down (SLC22A18)
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_002555

              Applied Biosystems Silencer® siRNAs for SLC22A18

              Sigma-Aldrich siRNA and siRNA Panels for SLC22A18  
                     Sigma-Aldrich shRNA for SLC22A18  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Browse Clone Ranger at Invitrogen for clones
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_002555
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_002555
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_002555 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_183233

UniProtKB/Swiss-Prot: S22AI_HUMAN, Q96BI1
Function: May act as a transporter of organic cations based on a proton efflux antiport mechanism.
May play a role in the transport of chloroquine and quinidine-related compounds in kidney

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005215 transporter activity TAS9499412
GO:0015293 symporter activity IEA--
GO:0015520 tetracycline:hydrogen antiporter activity IEA--
About this table

Pathways & Interactions
for SLC22A18

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section



5/7 Interacting proteins for SLC22A18 (ENSP000003078593) via UniProtKB, MINT, and/or STRING (see all 7 )
InteractantInteraction Details
GeneCardExternal ID(s)
PHLDA2ENSP000003192313STRING (score=.923)
KCNQ1ENSP000003701533STRING (score=.883)
RNF167ENSP000003707543STRING (score=.874)
UBE2E1ENSP000003037093STRING (score=.76)
--ENSP000003700663STRING (score=.886)
--ENSP000003109733STRING (score=.879)
--ENSP000002507073STRING (score=.87)
About this table

5 Gene Ontology (GO) biological process terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0006811 ion transport IEA--
GO:0007588 excretion TAS9744804
GO:0015904 tetracycline transport IEA--
GO:0042493 response to drug TAS9744804
GO:0046677 response to antibiotic IEA--
About this table

Drugs & Compounds
for SLC22A18

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for SLC22A18

Transcripts
for SLC22A18

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (SLC22A18)
Browse for Gene Knock-down Tools from Millipore
Abnova Chimera RNAi Products for Gene knock-down (SLC22A18)
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_002555

              Sigma-Aldrich siRNA and siRNA Panels for SLC22A18  
                     Sigma-Aldrich shRNA for SLC22A18  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_183233  

REFSEQ mRNAs for SLC22A18 gene (2 alternative transcripts): 

NM_002555.5   NM_183233.2   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_183233  

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_002555
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_002555
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_002555 

Additional cDNA sequence: 

AB012083.1 AF028738.1 AF030302.1 AF037064.1 AF059663.1 AF070479.1 BC015571.2 CR611681.1 

13 DOTS entries:

DT.113838  DT.110771  DT.91960671  DT.100775722  DT.100775724  DT.100024765  DT.100775723  DT.40130645 
DT.86853205  DT.95079254  DT.95079257  DT.95079260  DT.99951568 

24/118 AceView cDNA sequences (see all 118 ):

BF062704 BM561526 CR611681 CK823232 BM966890 CA454177 BM893589 AA535955 
CK823231 AF059663 BM893547 BE671759 BM893625 AI760091 BM966814 BM825077 
BI761173 BU194065 BM966767 AW009530 BQ447434 BM893646 BF434354 NM_002555 

highest scoring ESTs for SLC22A18:

AF030302 AA160738 AA406180 AA535955 AA573743 AA737813 AB012083 AF028738 AF037064 AF059663 

Unigene Cluster for SLC22A18:

Solute carrier family 22, member 18
Hs.50868  [show with all ESTs]
Unigene Representative Sequence: AF030302


GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for SLC22A18 (see all 8 )

ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b
SP1:                                      -                       -                       -     -                                 
SP2:                                                              -                       -     -                                 
SP3:                                      -                                                                                       
SP4:                                -     -                       -                                                               
SP5:                                                              -                                                               

About this scheme

ECgene alternative splicing isoforms for SLC22A18

3 Ensembl transcripts including schematic representations:
ENST00000380574  ENST00000347936  ENST00000312221  

Expression
for SLC22A18

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SLC22A18 expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for SLC22A18

1 / 2 / 3

3 probe-sets matching SLC22A18 gene


Affymetrix
probe-set		 Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
39992_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 AF030302 1.00 1.00 1.00 1

204981_at2, 3 U133-A 1 1.00 1.00 -- -- NM_002555 0.60 1.00 0.82 1

204981_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
GeneDecks  SLC22A18 for binary patterns associated with the probe-sets selected above  
About GeneDecksing
About this table    
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: CTGGGCCTCT

SOURCE GeneReport for Unigene cluster: Hs.50868

Expression variation in blood from EXPOLDB for SLC22A18

UniProtKB/Swiss-Prot: S22AI_HUMAN, Q96BI1
Tissue specificity: Expressed at high levels in adult and fetal kidney and liver, and adult colon.
Expressed in fetal renal proximal tubules (at protein level). Expressed at lower levels in heart,
brain and lung

Orthologs
for SLC22A18

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section
Orthologs for SLC22A18 gene from 5/10 species (see all 10 )
Organism Gene Locus Description Human
Similarity		 NCBI accessions
dog
(Canis familiaris)		 SLC22A181   -- solute carrier family 22, member 18 73.17(n)
65.95(a)		 475997  XM_533204.2  XP_533204.2 
chimpanzee
(Pan troglodytes)		 SLC22A181   -- solute carrier family 22, member 18 98.74(n)
98.08(a)		 450959  XM_001155046.1  XP_001155046.1 
cow
(Bos taurus)		 SLC22A181   -- solute carrier family 22, member 18 83.25(n)
79.25(a)		 504885  XM_869936.2  XP_875029.1 
rat
(Rattus norvegicus)		 Slc22a181   -- solute carrier family 22, member 18 78.13(n)
78.05(a)		 309131  NM_001004260.1  NP_001004260.1 
mouse
(Mus musculus)		 Slc22a181, 5 7 (69.50 cM)5
 solute carrier family 22 (organic cation transporter), more1, 5 78.59(n)1
78.92(a)1		 184001  NM_008767.21  NP_032793.21 
 AA0874285  AB0120845  (see all 18)
About this table        Species with no ortholog for SLC22A18

ENSEMBL Gene Tree for SLC22A18

Paralogs
for SLC22A18

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

Paralogs for SLC22A18 gene
MFSD92  MFSD102  

SNPs/Variants
for SLC22A18

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section


10/237 NCBI SNPs in SLC22A18 are shown (see all 237 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 141)
ABGenomic DataTranscription DataAllele Frequencies
SNP IDValidChr 11 posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
------------
rs107417351,2
A,C,F,H2876859(+) GCCCAA/GAGCCA 1 -- ng518Minor allele frequency- G:0.46EU EA WA 834
rs49300271,2
A,C,F,H2879069(+) CCACGG/ATGACT 2 -- ng51 int18Minor allele frequency- A:0.36EU EA WA 838
rs22832321,2
A,C,F,H2875709(+) AGTAAC/TGGTGA 1 -- ng512Minor allele frequency- T:0.32EA EU 1616
rs4184391,2
A,C,F,H2879178(+) CACCCT/AGTCTC 2 -- ng51 int14Minor allele frequency- A:0.37EU EA 1796
rs10480461,2
A,C,F2881167(+) CTCGGG/ACTCCC 2 T/A mis1 ese36Minor allele frequency- A:0.38MN NA EU EA WA 670
rs11297821,2
C,F,H2900247(+) GCCTGG/CATGTC 2 C/W mis16Minor allele frequency- C:0.11MN EU EA WA NA 654
rs4493181,2
C,F,H2876762(+) CCACCG/AGGCGG 1 -- ng514Minor allele frequency- A:0.04EU EA WA 410
rs10480471,2
A,C,F2881186(+) GGGCCA/GGTCCC 2 R/Q mis16Minor allele frequency- G:0.12MN NA EU EA WA 674
rs37648961,2
F,H2903098(+) CCTGCG/ATCCTT 2 -- ng315Minor allele frequency- A:0.12EA EU WA 1340
rs22379021,2
C,F2879281(+) GGGGAG/CGAGGT 2 -- ng51 int1 trp31Minor allele frequency- C:0.47EA 1482
About this table

HapMap Linkage Disequilibrium images for SLC22A18 (up to first 250kb)

Disorders & Mutations
for SLC22A18

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

 OMIM: 602631

UniProtKB/Swiss-Prot: S22AI_HUMAN, Q96BI1
  • Defects in SLC22A18 are associated with breast cancer [MIM:114480]
  • Defects in SLC22A18 are associated with lung cancer [MIM:211980]
  • Defects in SLC22A18 are the cause of rhabdomyosarcoma type 1 (RMS1) [MIM:268210].
    Rhabdomyosarcoma is a malignant tumor (sarcoma) derived from striated muscle

    • 6 Novoseek disease relationships for SLC22A18 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    beckwith-wiedemann syndrome 83.49 2 9520460 (1)
    hepatoblastoma 76.84 1 9570947 (1)
    wilms tumor 72.64 3 9751628 (2), 9570947 (1)
    rhabdomyosarcoma 67.99 1 9520460 (1)
    tumors 8.64 10 15239143 (3), 16314844 (2), 9520460 (2), 9751628 (1) (see all 5)
    breast cancer 6.00 2 16624517 (1), 9520460 (1)
    About this table

    Medical News
    for SLC22A18

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for SLC22A18

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/19 PubMed articles for SLC22A18 gene (see all 19 ):

    Search for SLC22A18

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SLC22A18

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 5002 HGNC: 10964 AceView: SLC22A18 Ensembl:ENSG00000110628 euGenes: HUgn5002
    ECgene: SLC22A18 H-InvDB: SLC22A18

    Other Databases showing SLC22A18

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing SLC22A18

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for SLC22A18 Genetics and Cytogenetics in Oncology and Haematology

    Licensable Technologies
    for SLC22A18

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for SLC22A18

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for SLC22A18:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
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     Predesigned and custom siRNAs for SLC22A18 Browse antibodies at Sigma-Aldrich
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for SLC22A18 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
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    Developed at the Crown Human Genome Center & Weizmann Institute of Science



    The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
    SLC22A18 Gene at Home site.
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