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Aliases for SLC22A18AS Gene

Aliases for SLC22A18AS Gene

  • Solute Carrier Family 22 Member 18 Antisense 2 3
  • Solute Carrier Family 22 (Organic Cation Transporter), Member 18 Antisense 2 3 5
  • Solute Carrier Family 22 (Organic Cation Transporter), Member 1-Like Antisense 2 3
  • Organic Cation Transporter-Like Protein 2 Antisense Protein 3 4
  • Solute Carrier Family 22 Member 1-Like Antisense Protein 3 4
  • Solute Carrier Family 22 Member 18 Antisense Protein 3 4
  • P27-Beckwith-Wiedemann Region 1 B 3 4
  • SLC22A1LS 3 4
  • P27-BWR1B 3 4
  • BWSCR1B 3 4
  • ORCTL2S 3 4
  • BWR1B 3 4
  • Beckwith-Wiedemann Syndrome Chromosome Region 1, Candidate B 3
  • Organic Cation Transporter-Like 2 Antisense 3
  • Beckwith-Wiedemann Region 1B 3

External Ids for SLC22A18AS Gene

Previous HGNC Symbols for SLC22A18AS Gene

  • SLC22A1LS

Previous GeneCards Identifiers for SLC22A18AS Gene

  • GC11M002866
  • GC11M002697
  • GC11M002910
  • GC11M002911
  • GC11M002915

Summaries for SLC22A18AS Gene

GeneCards Summary for SLC22A18AS Gene

SLC22A18AS (Solute Carrier Family 22 Member 18 Antisense) is a Protein Coding gene. Diseases associated with SLC22A18AS include Beckwith-Wiedemann Syndrome.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC22A18AS Gene

Genomics for SLC22A18AS Gene

Regulatory Elements for SLC22A18AS Gene

Enhancers for SLC22A18AS Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SLC22A18AS on UCSC Golden Path with GeneCards custom track

Promoters for SLC22A18AS Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SLC22A18AS on UCSC Golden Path with GeneCards custom track

Genomic Location for SLC22A18AS Gene

2,887,344 bp from pter
2,903,945 bp from pter
16,602 bases
Minus strand

Genomic View for SLC22A18AS Gene

Genes around SLC22A18AS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC22A18AS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC22A18AS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC22A18AS Gene

Proteins for SLC22A18AS Gene

  • Protein details for SLC22A18AS Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein
    Protein Accession:
    Secondary Accessions:
    • E9PLK8
    • O43563

    Protein attributes for SLC22A18AS Gene

    253 amino acids
    Molecular mass:
    27061 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLC22A18AS Gene


neXtProt entry for SLC22A18AS Gene

Proteomics data for SLC22A18AS Gene at MOPED

Post-translational modifications for SLC22A18AS Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC22A18AS Gene

No data available for DME Specific Peptides for SLC22A18AS Gene

Domains & Families for SLC22A18AS Gene

Protein Domains for SLC22A18AS Gene


Suggested Antigen Peptide Sequences for SLC22A18AS Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SLC22A18AS: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SLC22A18AS Gene

Function for SLC22A18AS Gene

genes like me logo Genes that share phenotypes with SLC22A18AS: view

Animal Model Products

CRISPR Products

miRNA for SLC22A18AS Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC22A18AS Gene

Localization for SLC22A18AS Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SLC22A18AS Gene

Pathways & Interactions for SLC22A18AS Gene

SuperPathways for SLC22A18AS Gene

No Data Available

Interacting Proteins for SLC22A18AS Gene

Gene Ontology (GO) - Biological Process for SLC22A18AS Gene


No data available for Pathways by source and SIGNOR curated interactions for SLC22A18AS Gene

Drugs & Compounds for SLC22A18AS Gene

No Compound Related Data Available

Transcripts for SLC22A18AS Gene

mRNA/cDNA for SLC22A18AS Gene

Unigene Clusters for SLC22A18AS Gene

Solute carrier family 22 (organic cation transporter), member 18 antisense:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC22A18AS Gene

No ASD Table

Relevant External Links for SLC22A18AS Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC22A18AS Gene

mRNA expression in normal human tissues for SLC22A18AS Gene

mRNA differential expression in normal tissues according to GTEx for SLC22A18AS Gene

This gene is overexpressed in Colon - Transverse (x11.7), Kidney - Cortex (x6.8), and Liver (x5.7).

Protein differential expression in normal tissues from HIPED for SLC22A18AS Gene

This gene is overexpressed in Urine (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SLC22A18AS Gene

SOURCE GeneReport for Unigene cluster for SLC22A18AS Gene Hs.300076

mRNA Expression by UniProt/SwissProt for SLC22A18AS Gene

Tissue specificity: Most abundantly expressed in gastrointestinal tissues. Expressed at lower levels in kidney and placenta. Expressed in fetal brain, liver, placenta, kidney and lung.
genes like me logo Genes that share expression patterns with SLC22A18AS: view

Protein tissue co-expression partners for SLC22A18AS Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for SLC22A18AS Gene

Orthologs for SLC22A18AS Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for SLC22A18AS Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SLC22A18AS 35
  • 98.81 (n)
  • 98.02 (a)
SLC22A18AS 36
  • 98 (a)
Species with no ortholog for SLC22A18AS:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SLC22A18AS Gene

Gene Tree for SLC22A18AS (if available)
Gene Tree for SLC22A18AS (if available)

Paralogs for SLC22A18AS Gene

No data available for Paralogs for SLC22A18AS Gene

Variants for SLC22A18AS Gene

Sequence variations from dbSNP and Humsavar for SLC22A18AS Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs2237901 -- 2,891,879(+) GGGGT(C/T)CCGCC intron-variant
rs2283230 -- 2,895,229(+) AGGGC(C/T)CCAGG intron-variant
rs2283231 -- 2,895,485(+) ATTGC(A/C/T)TGGGT intron-variant
rs11603948 -- 2,894,528(+) TTCAC(A/G)ATTCT intron-variant
rs7483664 -- 2,897,467(+) AAGCC(A/G)AGGCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC22A18AS Gene

Variant ID Type Subtype PubMed ID
dgv333e1 CNV Complex 17122850
dgv1006n71 CNV Loss 21882294
nsv469930 CNV Loss 18288195
dgv1007n71 CNV Loss 21882294
dgv1008n71 CNV Loss 21882294
nsv825715 CNV Gain 20364138
nsv467655 CNV Loss 19166990
dgv1009n71 CNV Loss 21882294
nsv832050 CNV Loss 17160897
nsv467657 CNV Loss 19166990
nsv896864 CNV Loss 21882294
dgv1010n71 CNV Loss 21882294
dgv1011n71 CNV Loss 21882294
esv2744015 CNV Deletion 23290073
esv2181696 CNV Deletion 18987734
dgv1012n71 CNV Loss 21882294
dgv1013n71 CNV Loss 21882294
nsv467658 CNV Loss 19166990

Variation tolerance for SLC22A18AS Gene

Gene Damage Index Score: 2.41; 42.58% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for SLC22A18AS Gene

Disorders for SLC22A18AS Gene

MalaCards: The human disease database

(1) MalaCards diseases for SLC22A18AS Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
beckwith-wiedemann syndrome
  • wiedemann-beckwith syndrome
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for SLC22A18AS

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with SLC22A18AS: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SLC22A18AS Gene

Publications for SLC22A18AS Gene

  1. Paternal imprinting of the SLC22A1LS gene located in the human chromosome segment 11p15.5. (PMID: 15175115) Bajaj V. … Kumar A. (BMC Genet. 2004) 2 3 4 23 67
  2. Divergently transcribed overlapping genes expressed in liver and kidney and located in the 11p15.5 imprinted domain. (PMID: 9570947) Cooper P.R. … Higgins M.J. (Genomics 1998) 2 3 23
  3. Promoter characterization and regulation of expression of an imprinted gene SLC22A18AS. (PMID: 18721868) Bajaj V. … Kumar A. (Gene 2008) 3 23
  4. Transcriptional map of 170-kb region at chromosome 11p15.5: identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples. (PMID: 9520460) Schwienbacher C. … Negrini M. (Proc. Natl. Acad. Sci. U.S.A. 1998) 2 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for SLC22A18AS Gene

Sources for SLC22A18AS Gene